Rapid Surface Display of mRNA Antigens by Bacteria‐Derived Outer Membrane Vesicles for a Personalized Tumor Vaccine

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

Kawai, T., & Akira, S. (2010) · Nature Immunology · doi:10.1038/ni.1863 · Cited by 9,304 · see citing works

mRNA vaccines — a new era in vaccinology

Pardi, N., Hogan, M. J., Porter, F. W., & Weissman, D. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2017.243 · Cited by 4,667 · see citing works

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

Sahin, U., Derhovanessian, E., Miller, M., Kloke, B.-P., Simon, P., Löwer, M., Bukur, V., Tadmor, A. D., Luxemburger, U., Schrörs, B., et al. (2017) · Nature · doi:10.1038/nature23003 · Cited by 2,488 · see citing works

mRNA-based therapeutics--developing a new class of drugs

Sahin, U., Karikó, K., & Türeci, Ö. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4278 · Cited by 2,474 · see citing works

Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions

Schwechheimer, C., & Kuehn, M. J. (2015) · Nature Reviews Microbiology · doi:10.1038/nrmicro3525 · Cited by 1,932 · see citing works

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

Kranz, L. M., Diken, M., Haas, H., Kreiter, S., Loquai, C., Reuter, K. C., Meng, M., Fritz, D., Vascotto, F., Hefesha, H., et al. (2016) · Nature · doi:10.1038/nature18300 · Cited by 1,771 · see citing works

Role of RNA modifications in cancer

Barbieri, I., & Kouzarides, T. (2020) · Nature reviews. Cancer · doi:10.1038/s41568-020-0253-2 · Cited by 1,322 · see citing works

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

Yadav, M., Jhunjhunwala, S., Phung, Q. T., Lupardus, P., Tanguay, J., Bumbaca, S., Franci, C., Cheung, T. K., Fritsche, J., Weinschenk, T., et al. (2014) · Nature · doi:10.1038/nature14001 · Cited by 1,186 · see citing works

Advances in the development of personalized neoantigen-based therapeutic cancer vaccines

Blass, E., & Ott, P. A. (2021) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-020-00460-2 · Cited by 1,042 · see citing works

Immune modulation by bacterial outer membrane vesicles

Kaparakis‐Liaskos, M., & Ferrero, R. L. (2015) · Nature reviews. Immunology · doi:10.1038/nri3837 · Cited by 1,028 · see citing works

A STING-activating nanovaccine for cancer immunotherapy

Luo, M., Wang, H., Wang, Z., Cai, H., Lu, Z., Li, Y., Du, M., Huang, G., Wang, C., Chen, X., et al. (2017) · Nature Nanotechnology · doi:10.1038/nnano.2017.52 · Cited by 904 · see citing works

Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson’s disease treatment

Kojima, R., Bojar, D., Rizzi, G., Hamri, G. C.-E., El-Baba, M. D., Saxena, P., Ausländer, S., Tan, K. R., & Fussenegger, M. (2018) · Nature Communications · doi:10.1038/s41467-018-03733-8 · Cited by 748 · see citing works

Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation

Miao, L., Li, L., Huang, Y., Delcassian, D., Chahal, J., Han, J., Shi, Y., Sadtler, K., Gao, W., Lin, J., et al. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0247-3 · Cited by 723 · see citing works

Bacterial outer membrane vesicles suppress tumor by interferon-γ-mediated antitumor response

Kim, O. Y., Park, H. T., Dinh, N. T. H., Choi, S. J., Lee, J., Kim, J. H., Lee, S.-W., & Gho, Y. S. (2017) · Nature Communications · doi:10.1038/s41467-017-00729-8 · Cited by 616 · see citing works

Bioengineered Bacterial Outer Membrane Vesicles as Cell-Specific Drug-Delivery Vehicles for Cancer Therapy

Gujrati, V., Kim, S.-H., Kim, S., Min, J. J., Choy, H. E., Kim, S. C., & Jon, S. (2014) · ACS Nano · doi:10.1021/nn405724x · Cited by 543 · see citing works

Multifunctional biomolecule nanostructures for cancer therapy

Wang, J., Li, Y., & Nie, G. (2021) · Nature Reviews Materials · doi:10.1038/s41578-021-00315-x · Cited by 505 · see citing works

The promise of mRNA vaccines: a biotech and industrial perspective

Jackson, N. A. C., Kester, K. E., Casimiro, D., Gurunathan, S., & DeRosa, F. (2020) · npj Vaccines · doi:10.1038/s41541-020-0159-8 · Cited by 498 · see citing works

Bioengineered bacteria-derived outer membrane vesicles as a versatile antigen display platform for tumor vaccination via Plug-and-Display technology

Cheng, K., Zhao, R., Li, Y., Qi, Y., Wang, Y., Zhang, Y., Qin, H., Qin, Y., Chen, L., Li, C., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22308-8 · Cited by 480 · see citing works

The structure of a cytolytic α-helical toxin pore reveals its assembly mechanism

Mueller, M., Grauschopf, U., Maier, T., Glockshuber, R., & Ban, N. (2009) · Nature · doi:10.1038/nature08026 · Cited by 331 · see citing works

Delivery of foreign antigens by engineered outer membrane vesicle vaccines

Chen, D. J., Osterrieder, N., Metzger, S. M., Buckles, E. L., Doody, A. M., DeLisa, M. P., & Putnam, D. A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0805532107 · Cited by 303 · see citing works

Listeriolysin O: the Swiss army knife of Listeria

Hamon, M. A., Ribet, D., Stavru, F., & Cossart, P. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.04.006 · Cited by 295 · see citing works

Charge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animals

McKinlay, C. J., Vargas, J. R., Blake, T. R., Hardy, J. W., Kanada, M., Contag, C. H., Wender, P. A., & Waymouth, R. M. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1614193114 · Cited by 288 · see citing works

Bacterial Outer Membrane Vesicles Presenting Programmed Death 1 for Improved Cancer Immunotherapy via Immune Activation and Checkpoint Inhibition

Li, Y., Zhao, R., Cheng, K., Zhang, K., Wang, Y., Zhang, Y., Li, Y., Liu, G., Xu, J., Xu, J., et al. (2020) · ACS Nano · doi:10.1021/acsnano.0c03776 · Cited by 281 · see citing works

A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer

Ni, Q., Zhang, F., Liu, Y., Wang, Z., Yu, G., Liang, B., Niu, G., Su, T., Zhu, G., Lu, G., et al. (2020) · Science Advances · doi:10.1126/sciadv.aaw6071 · Cited by 279 · see citing works

Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines

Chen, L., Qin, H., Zhao, R., Zhao, X., Lin, L., Chen, Y., Lin, Y., Li, Y., Qin, Y., Li, Y., et al. (2021) · Science Translational Medicine · doi:10.1126/scitranslmed.abc2816 · Cited by 240 · see citing works

A Hybrid Eukaryotic–Prokaryotic Nanoplatform with Photothermal Modality for Enhanced Antitumor Vaccination

Chen, Q., Huang, G., Wu, W., Wang, J., Hu, J., Mao, J., Chu, P. K.-H., Bai, H., & Tang, G. (2020) · Advanced Materials · doi:10.1002/adma.201908185 · Cited by 237 · see citing works

The three-dimensional structures of two complexes between recombinant MS2 capsids and RNA operator fragments reveal sequence-specific protein-RNA interactions

Valegard, K., Murray, J. B., Stonehouse, N. J., van den Worm, S., Stockley, P. G., & Liljas, L. (1997) · Journal of Molecular Biology · doi:10.1006/jmbi.1997.1144 · Cited by 230 · see citing works

An RNA toolbox for cancer immunotherapy

Pastor, F., Berraondo, P., Etxeberria, I., Frederick, J., Sahin, U., Gilboa, E., & Melero, I. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2018.132 · Cited by 229 · see citing works

Rapidly produced SAM ^® vaccine against H7N9 influenza is immunogenic in mice

Hekele, A., Bertholet, S., Archer, J., Gibson, D. G., Palladino, G., Brito, L. A., Otten, G. R., Brazzoli, M., Buccato, S., Bonci, A., et al. (2013) · Emerging Microbes & Infections · doi:10.1038/emi.2013.54 · Cited by 226 · see citing works

Increased Antigen Presentation Efficiency by Coupling Antigens to MHC Class I Trafficking Signals

Kreiter, S., Selmi, A., Diken, M., Sebastian, M., Osterloh, P., Schild, H., Huber, C., Türeci, Ö., & Şahin, U. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.1.309 · Cited by 221 · see citing works

Binding of L7Ae protein to the K-turn of archaeal snoRNAs: a shared RNA binding motif for C/D and H/ACA box snoRNAs in Archaea

Rozhdestvensky, T. S. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg175 · Cited by 214 · see citing works

The structure of trp RNA-binding attenuation protein

Antson, A. A., Otridge, J., Brzozowski, A. M., Dodson, E. J., Dodson, G. G., Wilson, K. S., Smith, T. M., Yang, M., Kurecki, T., & Gollnick, P. D. (1995) · Nature · doi:10.1038/374693a0 · Cited by 201 · see citing works

Targeting herpes simplex virus with CRISPR–Cas9 cures herpetic stromal keratitis in mice

Yin, D., Ling, S., Wang, D., Dai, Y., Jiang, H., Zhou, X., Paludan, S. R., Hong, J., & Cai, Y. (2021) · Nature Biotechnology · doi:10.1038/s41587-020-00781-8 · Cited by 188 · see citing works

Engineered Bacterial Outer Membrane Vesicles with Enhanced Functionality

Kim, J., Doody, A. M., Chen, D. J., Cremona, G. H., Shuler, M. L., Putnam, D. A., & DeLisa, M. P. (2008) · Journal of Molecular Biology · doi:10.1016/j.jmb.2008.03.076 · Cited by 184 · see citing works

Lentiviral delivery of co-packaged Cas9 mRNA and a Vegfa-targeting guide RNA prevents wet age-related macular degeneration in mice

Ling, S., Yang, S., Hu, X., Yin, D., Dai, Y., Qian, X., Wang, D., Pan, X., Hong, J., Sun, X., et al. (2021) · Nature Biomedical Engineering · doi:10.1038/s41551-020-00656-y · Cited by 182 · see citing works

Molecular Basis of Box C/D RNA-Protein Interactions

Moore, T., Zhang, Y., Fenley, M. O., & Li, H. (2004) · Structure · doi:10.1016/j.str.2004.02.033 · Cited by 168 · see citing works

RNA–protein interaction mapping via MS2- or Cas13-based APEX targeting

Han, S., Zhao, B. S., Myers, S. A., Carr, S. A., He, C., & Ting, A. Y. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2006617117 · Cited by 166 · see citing works

Recombinant M2e outer membrane vesicle vaccines protect against lethal influenza A challenge in BALB/c mice

Rappazzo, C. G., Watkins, H. C., Guarino, C., Chau, A., Lopez, J. L., DeLisa, M. P., Leifer, C. A., Whittaker, G. R., & Putnam, D. A. (2016) · Vaccine · doi:10.1016/j.vaccine.2016.01.028 · Cited by 141 · see citing works

Development of a Cancer Vaccine Using In Vivo Click‐Chemistry‐Mediated Active Lymph Node Accumulation for Improved Immunotherapy

Qin, H., Zhao, R., Qin, Y., Zhu, J., Chen, L., Di, C., Han, X., Cheng, K., Zhang, Y., Zhao, Y., et al. (2021) · Advanced Materials · doi:10.1002/adma.202006007 · Cited by 140 · see citing works

Evaluation of novel cationic gene based liposomes with cyclodextrin prepared by thin film hydration and microfluidic systems

Elsana, H., Olusanya, T. O. B., Carr‐Wilkinson, J., Darby, S., Faheem, A., & Elkordy, A. (2019) · Scientific Reports · doi:10.1038/s41598-019-51065-4 · Cited by 137 · see citing works

pH dependence of listeriolysin O aggregation and pore‐forming ability

Bavdek, A., Kostanjšek, R., Antonini, V., Lakey, J. H., Serra, M. D., Gilbert, R. J. C., & Anderluh, G. (2011) · FEBS Journal · doi:10.1111/j.1742-4658.2011.08405.x · Cited by 110 · see citing works

Lipid Nanovesicles by Microfluidics: Manipulation, Synthesis, and Drug Delivery

Liu, C., Feng, Q., & Sun, J. (2018) · Advanced Materials · doi:10.1002/adma.201804788 · Cited by 107 · see citing works

Lymph node conduits transport virions for rapid T cell activation

Reynoso, G. V., Weisberg, A. S., Shannon, J. P., McManus, D. T., Shores, L. S., Americo, J. L., Stan, R. V., Yewdell, J. W., & Hickman, H. D. (2019) · Nature Immunology · doi:10.1038/s41590-019-0342-0 · Cited by 90 · see citing works

How COVID unlocked the power of RNA vaccines

Dolgin, E. (2021) · Nature · doi:10.1038/d41586-021-00019-w · Cited by 90 · see citing works

Adjuvant effect of bacterial outer membrane vesicles with penta-acylated lipopolysaccharide on antigen-specific T cell priming

Lee, D. H., Kim, S., Kang, W., Choi, Y. S., Lee, S. H., Lee, S., You, S., Lee, H. K., Chang, K.-T., & Shin, E. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.08.102 · Cited by 74 · see citing works

MHC class II distribution in dendritic cells and B cells is determined by ubiquitin chain length

Jessica, K., Platt, M. Y., Eastham‐Anderson, J., Shin, J., & Mellman, I. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1202977109 · Cited by 69 · see citing works

Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET

Huynh, N., Ou, Q., Cox, P., Lill, R., & King‐Jones, K. (2019) · Nature Communications · doi:10.1038/s41467-019-13237-8 · Cited by 67 · see citing works

Bundling mRNA Strands to Prepare Nano‐Assemblies with Enhanced Stability Towards RNase for In Vivo Delivery

Yoshinaga, N., Cho, E., Koji, K., Mochida, Y., Naito, M., Osada, K., Kataoka, K., Cabral, H., & Uchida, S. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201905203 · Cited by 57 · see citing works

RNAIII activates map expression by forming an RNA-RNA complex in Staphylococcus aureus

Liu, Y., Mu, C., Ying, X., Li, W., Wu, N., Dong, J., Gao, Y., Shao, N., Fan, M., & Yang, G. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.02.021 · Cited by 55 · see citing works

Essential role of Toll-like receptor 2 in macrophage activation by glycogen

Kakutani, R., Adachi, Y., Takata, H., Kuriki, T., & Ohno, N. (2011) · Glycobiology · doi:10.1093/glycob/cwr122 · Cited by 47 · see citing works

High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers

Peng, W., Santos, M. D. S., Li, Y., Tomchick, D. R., & Orth, K. (2019) · PLoS ONE · doi:10.1371/journal.pone.0213423 · Cited by 47 · see citing works

Efficient expression of stabilized mRNA PEG-peptide polyplexes in liver

Crowley, S. T., Poliskey, J. A., Baumhover, N. J., & Rice, K. G. (2015) · Gene Therapy · doi:10.1038/gt.2015.68 · Cited by 35 · see citing works

Long-Range RNA Structural Information via a Paramagnetically Tagged Reporter Protein

Strickland, M., Catazaro, J., Rajasekaran, R., Strub, M., O’Hern, C., Bermejo, G. A., Summers, M. F., Marchant, J., & Tjandra, N. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.8b11384 · Cited by 21 · see citing works

Structure of a rare non-standard sequence k-turn bound by L7Ae protein

Huang, L., & Lilley, D. M. J. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku087 · Cited by 19 · see citing works

The role of RNA structure in translational regulation by L7Ae protein in archaea

Huang, L., Ashraf, S., & Lilley, D. M. J. (2018) · RNA · doi:10.1261/rna.068510.118 · Cited by 16 · see citing works

‘Just beautiful’: Another COVID-19 vaccine, from newcomer Moderna, succeeds in large-scale trial

Cohen, J. D. (2020) · Science · doi:10.1126/science.abf6962 · Cited by 4 · see citing works

Neoantigens: promising targets for cancer therapy

Xie, N., Shen, G., Gao, W., Huang, Z., Huang, C., & Fu, L. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01270-x · Cited by 1,020 · see citing works

The landscape of mRNA nanomedicine

Huang, X., Kong, N., Zhang, X., Cao, Y., Langer, R., & Tao, W. (2022) · Nature Medicine · doi:10.1038/s41591-022-02061-1 · Cited by 511 · see citing works

Lipid Nanoparticle (LNP) Enables mRNA Delivery for Cancer Therapy

Zong, Y., Lin, Y., Wei, T., & Cheng, Q. (2023) · Advanced Materials · doi:10.1002/adma.202303261 · Cited by 495 · see citing works

Circular RNA cancer vaccines drive immunity in hard-to-treat malignancies

Li, H., Peng, K., Yang, K., Ma, W., Qi, S., Yu, X., He, J., Lin, X., & Yu, G. (2022) · Theranostics · doi:10.7150/thno.77350 · Cited by 245 · see citing works

Engineered Bacterial Outer Membrane Vesicles as Controllable Two‐Way Adaptors to Activate Macrophage Phagocytosis for Improved Tumor Immunotherapy

Feng, Q., Ma, X., Cheng, K., Liu, G., Li, Y., Yue, Y., Liang, J., Zhang, L., Zhang, T., Wang, X., et al. (2022) · Advanced Materials · doi:10.1002/adma.202206200 · Cited by 211 · see citing works

Nanoparticle‐Based Photothermal Therapy for Breast Cancer Noninvasive Treatment

Xiong, Y., Rao, Y., Hu, J., Luo, Z., & Chen, C. (2023) · Advanced Materials · doi:10.1002/adma.202305140 · Cited by 188 · see citing works

Bacteria-derived nanovesicles enhance tumour vaccination by trained immunity

Liu, G., Ma, N., Cheng, K., Feng, Q., Ma, X., Yue, Y., Li, Y., Zhang, T., Gao, X., Liang, J., et al. (2023) · Nature Nanotechnology · doi:10.1038/s41565-023-01553-6 · Cited by 190 · see citing works

mRNA-based vaccines and therapeutics: an in-depth survey of current and upcoming clinical applications

Wang, Y., Kumari, M., Chen, G., Hong, M.-H., Yuan, J. P., Tsai, J.-L., & Wu, H. (2023) · Journal of Biomedical Science · doi:10.1186/s12929-023-00977-5 · Cited by 183 · see citing works

Extracellular Vesicles‐Derived Hybrid Nanoplatforms for Amplified CD47 Blockade‐Based Cancer Immunotherapy

Tang, L., Yin, Y., Cao, Y., Fu, C., Liu, H., Feng, J., Wang, W., & Liang, X. (2023) · Advanced Materials · doi:10.1002/adma.202303835 · Cited by 171 · see citing works

Exosome for mRNA delivery: Strategies and therapeutic applications

Iqbal, Z., Rehman, K., Mahmood, A., Shabbir, M., Liang, Y., Duan, L., & Zeng, H. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02634-x · Cited by 144 · see citing works

mRNA nanomedicine: Design and recent applications

Kubiatowicz, L. J., Mohapatra, A., Krishnan, N., Fang, R. H., & Zhang, L. (2022) · Exploration · doi:10.1002/exp.20210217 · Cited by 130 · see citing works

Topical drug delivery strategies for enhancing drug effectiveness by skin barriers, drug delivery systems and individualized dosing

Zhao, L., Chen, J., Bai, B., Song, G.-L., Zhang, J.-W., Yu, H., Huang, S.-W., Wang, Z., & Lu, G.-H. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1333986 · Cited by 143 · see citing works

From structural design to delivery: mRNA therapeutics for cancer immunotherapy

Zhou, F., Huang, L., Li, S., Yang, W., Chen, F., Cai, Z., Liu, X., Xu, W., Lehto, V., Lächelt, U., et al. (2023) · Exploration · doi:10.1002/exp.20210146 · Cited by 115 · see citing works

Lipid Nanoparticle (LNP) Delivery Carrier-Assisted Targeted Controlled Release mRNA Vaccines in Tumor Immunity

Wu, L., Li, X., Qian, X., Wang, S., Liu, J., & Yan, J. (2024) · Vaccines · doi:10.3390/vaccines12020186 · Cited by 125 · see citing works

Bacterial extracellular vesicles-based therapeutic strategies for bone and soft tissue tumors therapy

Liu, H., Zhang, H., Han, Y., Hu, Y., Geng, Z., & Su, J. (2022) · Theranostics · doi:10.7150/thno.78034 · Cited by 101 · see citing works

An Integrated Polymeric mRNA Vaccine without Inflammation Side Effects for Cellular Immunity Mediated Cancer Therapy

Huang, P., Jiang, L., Pan, H., Ding, L., Zhou, B., Zhao, M., Zou, J., Li, B., Qi, M., Deng, H., et al. (2022) · Advanced Materials · doi:10.1002/adma.202207471 · Cited by 95 · see citing works

Promising dawn in tumor microenvironment therapy: engineering oral bacteria

Wang, Z., Sun, W., Hua, R., Wang, Y., Li, Y., & Zhang, H. (2024) · International Journal of Oral Science · doi:10.1038/s41368-024-00282-3 · Cited by 97 · see citing works

Engineered Living Materials for Advanced Diseases Therapy

Xue, D. Q., Wu, W. H., Pan, P., & Zhang, X. (2023) · Advanced Materials · doi:10.1002/adma.202304963 · Cited by 93 · see citing works

Engineering nanoparticle toolkits for mRNA delivery

Sun, B. F., Wu, W., Narasipura, E. A., Ma, Y., Yu, C., Fenton, O. S., & Song, H. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.115042 · Cited by 93 · see citing works

Adjuvant physiochemistry and advanced nanotechnology for vaccine development

Ren, H., Jia, W., Xie, Y., Yu, M., & Chen, Y. (2023) · Chemical Society Reviews · doi:10.1039/d2cs00848c · Cited by 88 · see citing works

Engineered bacterial outer membrane vesicles: a versatile bacteria-based weapon against gastrointestinal tumors

Zheng, K., Feng, Y., Li, L., Kong, F., Gao, J., & Kong, X. (2024) · Theranostics · doi:10.7150/thno.85917 · Cited by 88 · see citing works

Living Leukocyte‐Based Drug Delivery Systems

Chen, Y., Qin, D., Zou, J., Li, X., Guo, X. D., Tang, Y., Chuang, L. I. U., Chen, W., Kong, N., Zhang, C. Y., et al. (2022) · Advanced Materials · doi:10.1002/adma.202207787 · Cited by 85 · see citing works

Bacterial Membrane Vesicles: Physiological Roles, Infection Immunology, and Applications

Gan, Y., Zhao, G., Wang, Z., Zhang, X., Wu, M. X., & Lu, M. (2023) · Advanced Science · doi:10.1002/advs.202301357 · Cited by 81 · see citing works

Engineered bacterial extracellular vesicles for osteoporosis therapy

Liu, H., Li, M., Zhang, T., Liu, X., Zhang, H., Geng, Z., & Su, J. (2022) · Chemical Engineering Journal · doi:10.1016/j.cej.2022.138309 · Cited by 79 · see citing works

Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor

Su, L., Tian, Y., Zheng, Q., Cao, Y., Yao, M., Wang, S., Xu, W., Xi, C., Clocchiatti, A., Nie, G., et al. (2024) · Cell chemical biology · doi:10.1016/j.chembiol.2024.01.002 · Cited by 78 · see citing works

Bacterial extracellular vesicles: A position paper by the microbial vesicles task force of the Chinese society for extracellular vesicles

Wen, M., Wang, J., Ou, Z., Nie, G., Chen, Y., Li, M., Wu, Z., Xiong, S., Zhou, H., Yang, Z., et al. (2023) · Interdisciplinary medicine · doi:10.1002/inmd.20230017 · Cited by 70 · see citing works

Bacteria-based immunotherapy for cancer: a systematic review of preclinical studies

Zhou, M., Tang, Y., Xu, W., Hao, X., Li, Y., Huang, S. Q., Xiang, D., & Wu, J. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1140463 · Cited by 71 · see citing works

In vivo production of CAR-T cells using virus-mimetic fusogenic nanovesicles

Zhao, G., Zhang, Y., Xu, C., & Wang, J. (2023) · 中国科学通报：英文版 · doi:10.1016/j.scib.2023.11.055 · Cited by 68 · see citing works

pH‐Responsive β‐Glucans‐Complexed mRNA in LNPs as an Oral Vaccine for Enhancing Cancer Immunotherapy

Luo, P.-K., Ho, H., Chiang, M., Chu, L., Chuang, Y., Lyu, P. C., Hu, I., Chang, W.-A., Peng, S., Jayakumar, J., et al. (2024) · Advanced Materials · doi:10.1002/adma.202404830 · Cited by 64 · see citing works

Bioengineered nanotechnology for nucleic acid delivery

Zhang, Y., Luo, J., Gui, X., Zheng, Y., Schaar, E., Liu, G., & Shi, J. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.10.034 · Cited by 61 · see citing works

mRNA therapies: Pioneering a new era in rare genetic disease treatment

Shen, G., Liu, J., Yang, H., Xie, N., & Yang, Y. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.03.056 · Cited by 61 · see citing works

Advances in Engineered Macrophages: A New Frontier in Cancer Immunotherapy

Yang, S., Wang, Y., Jia, J., Fang, Y., Yang, Y., Yuan, W., & Hu, J. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06616-7 · Cited by 60 · see citing works

Bacteria extracellular vesicle as nanopharmaceuticals for versatile biomedical potential

Ho, M. Y., Liu, S., & Xing, B. (2024) · Nano Convergence · doi:10.1186/s40580-024-00434-5 · Cited by 60 · see citing works

Vaccines’ New Era-RNA Vaccine

Zhou, W., Jiang, L., Liao, S., Wu, F., Yang, G., Hou, L., Liu, L., Pan, X., Jia, W. W.-G., & Zhang, Y. (2023) · Viruses · doi:10.3390/v15081760 · Cited by 62 · see citing works

Bacterial outer membrane vesicle-based cancer nanovaccines

Gao, X., Feng, Q., Wang, J., & Zhao, X. (2022) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2022.0452 · Cited by 56 · see citing works

Components, Formulations, Deliveries, and Combinations of Tumor Vaccines

Liu, T., Yao, W., Sun, W., Yuan, Y., Liu, C., Liu, X., Wang, X., & Jiang, H. (2024) · ACS Nano · doi:10.1021/acsnano.4c05065 · Cited by 56 · see citing works

Innovative Applications of Bacteria and Their Derivatives in Targeted Tumor Therapy

Zhu, D., Pan, W. X., Li, H., Hua, J., Zhang, C., & Zhao, K. (2025) · ACS Nano · doi:10.1021/acsnano.4c15237 · Cited by 56 · see citing works

Engineering Versatile Bacteria‐Derived Outer Membrane Vesicles: An Adaptable Platform for Advancing Cancer Immunotherapy

Luo, Z., Cheng, X., Feng, B., Fan, D., Liu, X., Xie, R., Luo, T., Wegner, S. V., Ma, D., Chen, F., et al. (2024) · Advanced Science · doi:10.1002/advs.202400049 · Cited by 55 · see citing works

Redox‐Responsive Polymeric Nanoparticle for Nucleic Acid Delivery and Cancer Therapy: Progress, Opportunities, and Challenges

Xu, L., Cao, Y., Ya, X., Li, R., & Xu, X. (2023) · Macromolecular Bioscience · doi:10.1002/mabi.202300238 · Cited by 53 · see citing works

Metal-polyphenol “prison” attenuated bacterial outer membrane vesicle for chemodynamics promoted in situ tumor vaccines

Nie, W., Jiang, A., Ou, X., Zhou, J., Li, Z., Liang, C., Huang, L.-L., Wu, G., & Xie, H. (2023) · Biomaterials · doi:10.1016/j.biomaterials.2023.122396 · Cited by 53 · see citing works

Oral delivery of therapeutic proteins by engineered bacterial type zero secretion system

Xu, G., Liu, S., Xia, B., Wan, Y., Zhang, S., Zhang, B., Wang, Z., Chen, J., Xiao, F., Liang, X., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-57153-6 · Cited by 53 · see citing works

Harnessing Engineered Immune Cells and Bacteria as Drug Carriers for Cancer Immunotherapy

Jiang, J., Huang, Y., Zeng, Z., & Zhao, C. (2023) · ACS Nano · doi:10.1021/acsnano.2c07607 · Cited by 52 · see citing works

Engineered bacterial extracellular vesicles for central nervous system diseases

Ji, N., Wang, F., Wang, M., Zhang, W. C., Liu, H., & Su, J. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.10.027 · Cited by 52 · see citing works

Targeting the Gut: A Systematic Review of Specific Drug Nanocarriers

Garbati, P., Picco, C., Magrassi, R., Signorello, P., Cacopardo, L., Serra, M. D., Faticato, M. G., Luca, M. D., Balestra, F., Scavo, M. P., et al. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16030431 · Cited by 50 · see citing works

Extracellular vesicles as carriers of mRNA: Opportunities and challenges in diagnosis and treatment

Kirian, R. D., Steinman, D., Jewell, C. M., & Zierden, H. C. (2024) · Theranostics · doi:10.7150/thno.93115 · Cited by 46 · see citing works

Cellular Trafficking of Nanotechnology‐Mediated mRNA Delivery

Huang, P., Deng, H., Wang, C., Zhou, Y., & Chen, X. S. (2023) · Advanced Materials · doi:10.1002/adma.202307822 · Cited by 49 · see citing works

Synthetic Biology‐Based Engineering Cells for Drug Delivery

Yi, W., Hu, S., Qian, X., Yan, W., & Li, Y. (2025) · Exploration · doi:10.1002/exp.20240095 · Cited by 47 · see citing works

Recent Advances in Bacteria-Based Cancer Treatment

Wei, X., Du, M., Chen, Z., & Yuan, Z. (2022) · Cancers · doi:10.3390/cancers14194945 · Cited by 46 · see citing works

Extracellular Vesicles as Delivery Vehicles for Therapeutic Nucleic Acids in Cancer Gene Therapy: Progress and Challenges

Du, R., Wang, C., Zhu, L., & Yang, Y. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14102236 · Cited by 44 · see citing works

Current Landscape and Future Directions in Cancer Immunotherapy: Therapies, Trials, and Challenges

Bandara, S., & Raveendran, S. (2025) · Cancers · doi:10.3390/cancers17050821 · Cited by 46 · see citing works

Bacteria and Bacterial Components as Natural Bio-Nanocarriers for Drug and Gene Delivery Systems in Cancer Therapy

Zong, R. L., Ruan, H., Liu, C., Fan, S., & Li, J. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15102490 · Cited by 45 · see citing works

Lipid Nanoparticle-Based Delivery SystemA Competing Place for mRNA Vaccines

Zhang, X., Li, Y., & Zhou, Z. (2024) · ACS Omega · doi:10.1021/acsomega.3c08353 · Cited by 43 · see citing works

Advances and applications of RNA vaccines in tumor treatment

Yang, R., & Cui, J. (2024) · Molecular Cancer · doi:10.1186/s12943-024-02141-5 · Cited by 48 · see citing works

Advanced nano-based strategies for mRNA tumor vaccine

Qu, Y., Xu, J., Zhang, T., Chen, Q., Sun, T., & Jiang, C. (2023) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2023.07.025 · Cited by 42 · see citing works

Antigen Self-Presented Personalized Nanovaccines Boost the Immunotherapy of Highly Invasive and Metastatic Tumors

Wang, T., Han, M., Han, Y., Jiang, Z., Zheng, Q. Y., Zhang, H., & Li, Z. (2024) · ACS Nano · doi:10.1021/acsnano.3c11189 · Cited by 42 · see citing works

Bioinspired cellular membrane-derived vesicles for mRNA delivery

Xu, X., Xu, L., Wang, J., Wen, C., Xia, J., Zhang, Y., & Liang, Y. (2024) · Theranostics · doi:10.7150/thno.93755 · Cited by 41 · see citing works

Engineered extracellular vesicles as a next-generation vaccine platform

Lu, M., Xing, H., Zhao, X., Huang, Y., Zheng, A., & Liang, X. (2024) · Matter · doi:10.1016/j.matt.2024.09.012 · Cited by 41 · see citing works

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

Li, Q., Xing, H., Naeem, A., Zhang, K., Zheng, A., Huang, Y., & Lu, M. (2025) · Exploration · doi:10.1002/exp.20240109 · Cited by 42 · see citing works

Bacteria-Driven Tumor Microenvironment-Sensitive Nanoparticles Targeting Hypoxic Regions Enhances the Chemotherapy Outcome of Lung Cancer

Shi, H., Chen, L., Liu, Y., Wen, Q., Lin, S., Wen, Q., Lu, Y., Dai, J., Li, J., Xiao, S., et al. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s396863 · Cited by 39 · see citing works

Interleukin-12 Delivery Strategies and Advances in Tumor Immunotherapy

He, Q., Dong, C., Tan, D., Sun, H., Li, Z., Zheng, Y., Zhang, L., Liu, S., & Zhang, Y. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46100686 · Cited by 38 · see citing works

Outer Membrane Vesicles as a Versatile Platform for Vaccine Development: Engineering Strategies, Applications and Challenges

Garling, A., Auvray, F., Epardaud, M., Oswald, É., & Branchu, P. (2025) · Journal of Extracellular Vesicles · doi:10.1002/jev2.70150 · Cited by 39 · see citing works

Ultrasound Responsive Nanovaccine Armed with Engineered Cancer Cell Membrane and RNA to Prevent Foreseeable Metastasis

Sun, W., Ji, P., Zhou, T., Li, Z., Xing, C., Zhang, L., Wei, M., Yang, G., & Yuan, L. (2023) · Advanced Science · doi:10.1002/advs.202301107 · Cited by 37 · see citing works

Recent progress in cancer vaccines and nanovaccines

Poudel, K., Vithiananthan, T., Kim, J. O., & Tsao, H. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122856 · Cited by 40 · see citing works

Endotoxin-Free Outer Membrane Vesicles for Safe and Modular Anticancer Immunotherapy

Chen, M.-Y., Cheng, T.-W., Pan, Y., Mou, C., Chiang, Y., Lin, W., Hu, C. J., & Mou, K. Y. (2025) · ACS Synthetic Biology · doi:10.1021/acssynbio.4c00483 · Cited by 37 · see citing works

Cell‐Based Drug Delivery Systems Participate in the Cancer Immunity Cycle for Improved Cancer Immunotherapy

Fan, X., Wang, K., Qi, L., Lu, Y., & Sun, J. (2022) · Small · doi:10.1002/smll.202205166 · Cited by 37 · see citing works

A Potent Micron Neoantigen Tumor Vaccine GP‐Neoantigen Induces Robust Antitumor Activity in Multiple Tumor Models

Jing, Z., Wang, S., Xu, K., Tang, Q., Li, W., Zheng, W., Shi, H., Su, K., Liu, Y., & Hong, Z. (2022) · Advanced Science · doi:10.1002/advs.202201496 · Cited by 36 · see citing works

Nanoformulations targeting immune cells for cancer therapy: mRNA therapeutics

Yang, W., Cao, J., Cheng, H., Chen, L., Yu, M., Chen, Y., & Cui, X. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.11.014 · Cited by 36 · see citing works

Advancing cancer gene therapy: the emerging role of nanoparticle delivery systems

Wang, M., Liu, H., Huang, J., Cai, T., Xu, Z. P., & Zhang, L. L. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03433-8 · Cited by 36 · see citing works

Bacterial extracellular vesicles for gut microbiome–host communication and drug development

Qian, D., Xu, P., Wang, X., Du, C., Zhao, X., & Xu, J. (2025) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2025.03.008 · Cited by 36 · see citing works

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

Wang, H., Zhan, H., Pan, B., Zeng, L., Chen, Z., Liu, S., Zhang, Q., Hong, X., Lu, J., Lin, X., et al. (2025) · Advanced Materials · doi:10.1002/adma.202501565 · Cited by 33 · see citing works

Targeted miR-34a delivery with PD1 displayed bacterial outer membrane vesicles-coated zeolitic imidazolate framework nanoparticles for enhanced tumor therapy

Cui, C., He, Q., Wang, J., Kang, J., Ma, W., Nian, Y., Sun, Z., & Weng, H. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125692 · Cited by 33 · see citing works

Emerging prospects of mRNA cancer vaccines: mechanisms, formulations, and challenges in cancer immunotherapy

Laila, U. E., An, W., & Xu, Z.-X. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1448489 · Cited by 34 · see citing works

Advances in bacteria‐based drug delivery systems for anti‐tumor therapy

Han, S., Yifei, S., Wu, X., Zhanbo, Q., Xiang, Y., & Yang, X. (2024) · Clinical & Translational Immunology · doi:10.1002/cti2.1518 · Cited by 33 · see citing works

Path towards mRNA delivery for cancer immunotherapy from bench to bedside

Chen, W., Zhu, Y., He, J., & Sun, X. (2023) · Theranostics · doi:10.7150/thno.89247 · Cited by 31 · see citing works

RNA Nanomedicine: Delivery Strategies and Applications

Byun, J., Wu, Y., Park, J.-W., Kim, J. S., Li, Q., Choi, J., Shin, N., Lan, M., Cai, Y., Lee, J., et al. (2023) · The AAPS Journal · doi:10.1208/s12248-023-00860-z · Cited by 30 · see citing works

Self‐Oxygenated Biomimetic Nanozyme for Tumor Catalytic Immunotherapy

Zhang, B., Yuan, Y., Qi, X., Wang, S., Feng, Y., Yan, X., Fan, T., Jiang, B., & Yue, Y. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202411103 · Cited by 30 · see citing works

Engineering nanoplatforms of bacterial outer membrane vesicles to overcome cancer therapy resistance

Chai, Q., Li, D., Zhang, M., Gu, Y., Li, A., Wu, X., Liu, X., & Liu, J. (2025) · Drug Resistance Updates · doi:10.1016/j.drup.2025.101277 · Cited by 30 · see citing works

Glioblastoma Cell Derived Exosomes as a Potent Vaccine Platform Targeting Primary Brain Cancers and Brain Metastases

Zou, Y., Li, S., Li, Y., Zhang, D., Zheng, M., & Shi, B. (2025) · ACS Nano · doi:10.1021/acsnano.4c14573 · Cited by 30 · see citing works

Bioengineering Outer-Membrane Vesicles for Vaccine Development: Strategies, Advances, and Perspectives

Zahid, A., Ismail, H., Wilson, J. C., & Grice, I. D. (2025) · Vaccines · doi:10.3390/vaccines13070767 · Cited by 29 · see citing works

Research progress of nanovaccine in anti-tumor immunotherapy

Yao, M., Liu, X., Qian, Z., Fan, D., Sun, X., Zhong, L., & Wu, P. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1211262 · Cited by 29 · see citing works

Utilizing Engineered Bacteria as “Cell Factories” In Vivo for Intracellular RNA-Loaded Outer Membrane Vesicles’ Self-Assembly in Tumor Treatment

Sun, D., Li, Y., Yin, X., Fan, Y., Liu, J., Wang, Y., Liu, X., Bai, G., Li, K., Shi, Y., et al. (2024) · ACS Nano · doi:10.1021/acsnano.4c11412 · Cited by 28 · see citing works

Bioengineered bacterial outer membrane vesicles encapsulated Polybia–mastoparan I fusion peptide as a promising nanoplatform for bladder cancer immune-modulatory chemotherapy

Ren, C., Li, Y., Cong, Z., Li, Z., Xie, L., & Wu, S. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1129771 · Cited by 28 · see citing works

Application of stimuli responsive nanocomposites in drug delivery and theranostics to counter cancer proliferation and drug resistance

Khanna, N., Chatterji, T., Singh, S., & Pandey, S. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104958 · Cited by 28 · see citing works

Cancer‐Associated Fibroblasts: Heterogeneity, Cancer Pathogenesis, and Therapeutic Targets

Li, Y., Liu, Q., Jing, X., Wang, Y., Jia, X., Yang, X., & Chen, K. (2025) · MedComm · doi:10.1002/mco2.70292 · Cited by 29 · see citing works

A coordinative dendrimer-based nanovaccine for cancer treatment

Cao, Z., Ren, L., Niu, L., Zhao, R., Liu, N., Zhuang, Q., Pan, F., Liu, Z., Cheng, Y., Yang, Y., et al. (2023) · Matter · doi:10.1016/j.matt.2023.08.001 · Cited by 27 · see citing works

Harnessing enucleated cancer cells as Trojan horse cell vaccines

Fang, W., Jing, Z., Li, Y., Zhang, Z., Lin, Z., Yang, Z., Tian, Y., Zhang, C., Ma, Y., Hou, L., et al. (2023) · Cell Reports Physical Science · doi:10.1016/j.xcrp.2023.101752 · Cited by 27 · see citing works

Diverse drug delivery systems for the enhancement of cancer immunotherapy: an overview

Liu, X., Cheng, Y., Mu, Y., Zhang, Z., Tian, D., Liu, Y., Hu, X., & Wen, T. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1328145 · Cited by 27 · see citing works

Unlocking the power of nanomedicine: Cell membrane-derived biomimetic cancer nanovaccines for cancer treatment

Zhao, G., Wang, S., Nie, G., & Li, N. (2024) · Med · doi:10.1016/j.medj.2024.03.012 · Cited by 26 · see citing works

Screening Natural Cholesterol Analogs to Assemble Self‐Adjuvant Lipid Nanoparticles for Antigens Tagging Guided Therapeutic Tumor Vaccine

Liang, S., Gao, S., Fu, S., Yuan, S., Liu, J., Liang, M., Han, L., Zhang, Z., Liu, Y., & Zhang, N. (2025) · Advanced Materials · doi:10.1002/adma.202419182 · Cited by 26 · see citing works

Harnessing Bacterial Membrane Components for Tumor Vaccines: Strategies and Perspectives

Bai, Z., Wang, X., Liang, T., Xu, G., Cai, J., Xu, W., Yang, K., Hu, L. T., & Pei, P. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202401615 · Cited by 25 · see citing works

Hybrid mRNA Nano Vaccine Potentiates Antigenic Peptide Presentation and Dendritic Cell Maturation for Effective Cancer Vaccine Therapy and Enhances Response to Immune Checkpoint Blockade

Shi, L. D., Yang, J., Nie, Y., Huang, Y., & Gu, H. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202301261 · Cited by 25 · see citing works

Micro‐to‐Nano Oncolytic Microbial System Shifts from Tumor Killing to Tumor Draining Lymph Nodes Remolding for Enhanced Immunotherapy

Chen, Z., Liu, Y., Yu, Y., Yang, S., Feng, J. Q., Zhu, Y., Huang, W., Qin, B. Y., Guan, X., He, Z., et al. (2023) · Advanced Materials · doi:10.1002/adma.202306488 · Cited by 25 · see citing works

Recent Progress in Extracellular Vesicle-Based Carriers for Targeted Drug Delivery in Cancer Therapy

Tang, Y., Liu, X., Sun, M., Xiong, S., Xiao, N., Li, J., He, X., & Xie, J. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15071902 · Cited by 24 · see citing works

Adjuvants for cancer mRNA vaccines in the era of nanotechnology: strategies, applications, and future directions

Cao, L., Yu, Y.-F., Li, Z., Zhong, N., Wang, G.-R., Xiao, Y., Liu, B., Wu, Q., Feng, C., & Bu, L. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02590-6 · Cited by 23 · see citing works

Lysosome‐Targeting Bacterial Outer Membrane Vesicles for Tumor Specific Degradation of PD‐L1

Ji, P., Wu, P., Wang, L., Wang, Y., Guo, X., Gao, R., Guo, Z., Zhou, H., Liu, Z., Liang, Y., et al. (2024) · Small · doi:10.1002/smll.202400770 · Cited by 21 · see citing works

Advances in nanotechnology-based approaches for the treatment of head and neck squamous cell carcinoma

Tang, B., Huang, R., & Wen-juan, M. (2024) · RSC Advances · doi:10.1039/d4ra07193j · Cited by 21 · see citing works

Harnessing Bacterial Extracellular Vesicle Immune Effects for Cancer Therapy

Karaman, İ., Pathak, A., Bayık, D., & Watson, D. C. (2024) · Pathogens and Immunity · doi:10.20411/pai.v9i1.657 · Cited by 19 · see citing works

Lipid nanoparticle-mediated targeted mRNA delivery and its application in cancer therapy

Sui, Y., Hou, X., Zhang, J., Hong, X., Wang, H., Xiao, Y., & Zeng, X. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb01556a · Cited by 23 · see citing works

Hyperbaric oxygen augments chemodynamic effect induced by probiotic-derived selenium nanoparticles to enhance cancer immune checkpoint blockade therapy

Li, P., Yao, Y., Chen, X., Song, C. Q., Wu, M., Huang, J., Wang, D., Li, X., Luo, B., Yang, X., et al. (2023) · Chemical Engineering Journal · doi:10.1016/j.cej.2023.145738 · Cited by 20 · see citing works

Nanoscale synthetic biology with innovative medicinal applications

Ji, J., Li, L., Guo, W., Zhang, J., Yao, Y., Chen, H., Liao, F., Jin, Z., Liu, L., Ouyang, J., et al. (2024) · Fundamental Research · doi:10.1016/j.fmre.2024.11.006 · Cited by 19 · see citing works

mRNA Delivery Platform Based on Bacterial Outer Membrane Vesicles for Tumor Vaccine

Gao, X., Li, Y., Nie, G., & Zhao, X. (2023) · BIO-PROTOCOL · doi:10.21769/bioprotoc.4774 · Cited by 12 · see citing works

Bacterial Membrane Coating Potentiates Lipid Nanoparticles for mRNA Delivery

Wang, R., Bao, L., Yu, Y., Zhang, R., Guo, Z., Kubiatowicz, L. J., Krishnan, N., Noh, I., Wang, E., Fang, R. H., et al. (2025) · Nano Letters · doi:10.1021/acs.nanolett.5c04371 · Cited by 6 · see citing works

Bioengineered bacteria-derived outer membrane vesicles as a versatile antigen display platform for tumor vaccination via Plug-and-Display technology

Cheng, K., Zhao, R., Li, Y., Qi, Y., Wang, Y., Zhang, Y., Qin, H., Qin, Y., Chen, L., Li, C., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22308-8 · Cited by 480 · see citing works

Antigen-bearing outer membrane vesicles as tumour vaccines produced in situ by ingested genetically engineered bacteria

Yue, Y., Xu, J., Li, Y., Cheng, K., Feng, Q., Ma, X., Ma, N., Zhang, T., Wang, X., Zhao, X., et al. (2022) · Nature Biomedical Engineering · doi:10.1038/s41551-022-00886-2 · Cited by 269 · see citing works

Amplifying STING activation by biomimetic manganese mRNA nanovaccines for local and systemic cancer immunotherapy

He, C., Shi, C., Fang, M., Chang, P., Hou, P., Zhang, Y., & Li, J. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.113788 · Cited by 5 · see citing works