The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Atherosclerosis and risk for dementia
Abstract
Objective: Atherosclerosis has been implicated in the development of dementia and its major subtypes, Alzheimer's disease and vascular dementia. However, support for this association mainly comes from cross‐sectional studies. We investigated the association of atherosclerosis with dementia and subtypes of dementia during long follow‐up, with various noninvasive measures of atherosclerosis. Methods: This study was based on 6,647 participants in the Rotterdam Study, a population‐based prospective cohort study among 7,983 elderly subjects. At baseline (1990–1993) and at the third survey (1997–1999), common carotid intima media thickness, carotid plaques, and peripheral arterial disease (measured as ankle–brachial index) were measured. During follow‐up (mean, 9.0 years), 678 subjects developed dementia. We estimated the associations of different measures of atherosclerosis with risk for dementia and subtypes of dementia by means of Cox proportional hazard models. Analyses were repeated and stratified on duration of follow‐up. To evaluate competing risk for mortality, we examined the association between measures of atherosclerosis and risk for dementia or mortality by combining the two in a single outcome measure. Results: We found that atherosclerosis, predominantly carotid atherosclerosis, was associated with an increased risk for dementia during short follow‐up. This association attenuated with longer follow‐up, likely because of the strong association between atherosclerosis and mortality. The associations did not differ across apolipoprotein E genotypes. Interpretation: Our findings suggest that atherosclerosis is associated with an increased risk for dementia. Stronger associations between atherosclerosis and mortality may attenuate the association between atherosclerosis and dementia in prospective cohort studies with long follow‐up periods. Ann Neurol 2007
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Silent Brain Infarcts and the Risk of Dementia and Cognitive Decline
Vermeer, S. E., Prins, N. D., den Heijer, T., Hofman, A., Koudstaal, P. J., & Breteler, M. M. B. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022066 · Cited by 2,313
Self-citationRoth, M., Tym, E., Mountjoy, C. Q., Huppert, F. A., Hendrie, H., Verma, S., & Goddard, R. (1986) · British Journal of Psychiatry · doi:10.1192/bjp.149.6.698 · Cited by 2,090
Cardiovascular risk factors and cognitive decline in middle-aged adults
Knopman, D., Boland, L. L., Mosley, T., Howard, G., Liao, D., Szklo, M., McGovern, P., & Folsom, A. R. (2001) · Neurology · doi:10.1212/wnl.56.1.42 · Cited by 883
Incidence and Risk Factors of Silent Brain Infarcts in the Population-Based Rotterdam Scan Study
Vermeer, S. E., den Heijer, T., Koudstaal, P. J., Oudkerk, M., Hofman, A., & Breteler, M. M. B. (2003) · Stroke · doi:10.1161/01.str.0000052631.98405.15 · Cited by 680
Self-citationIncidence and Risk of Dementia: The Rotterdam study
Ott, A., Breteler, M. M. B., Harskamp, F. V., Stijnen, T., & Hofman, A. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009489 · Cited by 455 · cited 3×
“In addition, the total cohort was continuously monitored for incident dementia through computerized linkage between the study database and digitalized medical records from general practitioners and the Regional Institute for Outpatient Mental Health Care.(8) The diagnosis of dementia and subtype of dementia was made i…”
MethodSelf-citation
Cited by
mice: Multivariate Imputation by Chained Equations in R
Buuren, S. V., & Groothuis-Oudshoorn, K. (2011) · Journal of Statistical Software · doi:10.18637/jss.v045.i03 · Cited by 13,870
Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention
Qiu, C., Kivipelto, M., & von Strauss, E. (2009) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2009.11.2/cqiu · Cited by 1,261
Arvanitakis, Z., Capuano, A. W., Leurgans, S. E., Bennett, D. A., & Schneider, J. A. (2016) · The Lancet Neurology · doi:10.1016/s1474-4422(16)30029-1 · Cited by 581
Deckers, K., van Boxtel, M. P. J., Schiepers, O. J. G., de Vugt, M., Muñoz Sánchez, J. L., Anstey, K. J., Brayne, C., Dartigues, J.-F., Engedal, K., Kivipelto, M., et al. (2015) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4245 · Cited by 534
Grammas, P. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-26 · Cited by 432
Brain in Congenital Heart Disease Across the Lifespan: The Cumulative Burden of Injury
Marelli, A., Miller, S. P., Marino, B. S., Jefferson, A. L., & Newburger, J. W. (2016) · Circulation · doi:10.1161/circulationaha.115.019881 · Cited by 359
Periodontitis is associated with cognitive impairment among older adults: Analysis of NHANES-III
Noble, J. M., Borrell, L. N., Papapanou, P. N., Elkind, M. S. V., Scarmeas, N., & Wright, C. B. (2009) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2009.174029 · Cited by 324
The Impact of Disease Comorbidities in Alzheimer’s Disease
Santiago, J. A., & Potashkin, J. A. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.631770 · Cited by 259
Effect of infarcts on dementia in the Baltimore longitudinal study of aging
Troncoso, J. C., Zonderman, A. B., Resnick, S. M., Crain, B., Pletnikova, O., & O'Brien, R. J. (2008) · Annals of Neurology · doi:10.1002/ana.21413 · Cited by 219
Atherosclerotic calcification is related to a higher risk of dementia and cognitive decline
Bos, D., Vernooij, M. W., de Bruijn, R. F. A. G., Koudstaal, P. J., Hofman, A., Franco, O. H., van der Lugt, A., & Ikram, M. A. (2015) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2014.05.1758 · Cited by 142
Self-citationHomocysteine and holotranscobalamin and the risk of Alzheimer disease: A longitudinal study
Hooshmand, B., Solomon, A., Kåreholt, I., Leiviskä, J., Rusanen, M., Ahtiluoto, S., Winblad, B., Laatikainen, T., Soininen, H., & Kivipelto, M. (2010) · Neurology · doi:10.1212/wnl.0b013e3181f88162 · Cited by 122
Altered cerebral hemodynamics in early Alzheimer disease: a pilot study using transcranial Doppler
Claassen, J. A. H. R., Diaz-Arrastia, R., Martin-Cook, K., Levine, B. D., & Zhang, R. (2009) · Journal of Alzheimer's Disease · doi:10.3233/jad-2009-1079 · Cited by 95
Shared genetic contribution to ischemic stroke and Alzheimer's disease
Traylor, M., Adib‐Samii, P., Harold, D., the Alzheimer's Disease Neuroimaging Initiative, T. I. S. G. C. (., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., & and the METASTROKE and International Genomics of Alzheimer's Project (IGAP) investigators (2016) · Annals of Neurology · doi:10.1002/ana.24621 · Cited by 71
Babiloni, C., Pievani, M., Vecchio, F., Geroldi, C., Eusebi, F., Fracassi, C., Fletcher, E., De Carli, C., Boccardi, M., Rossini, P. M., et al. (2009) · Human Brain Mapping · doi:10.1002/hbm.20612 · Cited by 75
Brain microvasculature and hypoxia-related proteins in Alzheimer's disease.
(2011) · PubMed Central · Cited by 65
Homocysteine and inflammation: Predictors of cognitive decline in older persons?
van den Kommer, T. N., Dik, M. G., Comijs, H. C., Jonker, C., & Deeg, D. J. H. (2010) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.09.009 · Cited by 53
Gao, H., Song, R., Li, Y., Zhang, W., Wan, Z., Wang, Y., Zhang, H., & Han, S. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c05677 · Cited by 38
Metadata
- Authors
- van Oijen, M., Jan de Jong, F., Witteman, J. C. M., Hofman, A., Koudstaal, P. J., & Breteler, M. M. B.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 2007-02-27
- Volume
- 61
- Issue
- 5
- Pages
- 403-410
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2040291320
- Cited by
- 312
- References
- 5
- FWCI
- 11.10
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
