Cited by 180Obsessive-Compulsive Spectrum DisordersNeurotransmitter Receptor Influence on BehaviorSchizophrenia research and treatment

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Dopaminergic dysfunction in tourette syndrome

Singer, Harvey S., Butler, Ian J., Tune, Larry E., Seifert, William E., Coyle, Joseph T.·1982·Annals of Neurology

DOI 10.1002/ana.410120408

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Abstract

A prospective clinical and biochemical study on the effects of treatment with haloperidol has been performed in seven patients with Tourette syndrome. Pretteatment cerebrospinal fluid levels of homovanillic acid (CSF HV A) were significantly reduced in all patients, whereas 5‐hydroxyindoleacetic acid was reduced in only two. With haloperidol treatment, symptoms decreased in all cases (21 to 88%) and clinical improvement was associated withan increased level of CSF HV A, often returning to the normal range. Optimal therapeutic response was found with serum levels of haloperidol between 1 and 4 ng/ml; however, disturbing side effects also occurred within this range. These results support the hypothesis that Tourette syndrome may result form a supersensitivity of dopaminergic receptors.

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Antischizophrenic Drugs and Brain Cholinergic Receptors
Snyder, S. H. (1974) · Archives of General Psychiatry · doi:10.1001/archpsyc.1974.01760130040006 · Cited by 475
A simple and sensitive radioreceptor assay for antischizophrenic drugs in blood
Creese, I., & Snyder, S. H. (1977) · Nature · doi:10.1038/270180a0 · Cited by 239
Simultaneous determination of the three major monoamine metabolites in brain tissue and body fluids by a mass fragmentographic method
Swahn, C., Sandg�rde, B., Wiesel, F., & Sedvall, G. (1976) · Psychopharmacology · doi:10.1007/bf00423253 · Cited by 229
CLONIDINE IN TOURETTE'S SYNDROME
Cohen, D. J., Nathanson, J. A., Young, J. G., & Shaywitz, B. A. (1979) · The Lancet · doi:10.1016/s0140-6736(79)91614-3 · Cited by 191
Biogenic amine metabolism in tourette syndrome
Butler, I. J., Koslow, S. H., Seifert, W. E., Caprioli, R. M., & Singer, H. S. (1979) · Annals of Neurology · doi:10.1002/ana.410060109 · Cited by 185
Self-citation
Gilles de la Tourette syndrome after long‐term chlorpromazine therapy
Klawans, H. L., Falk, D. K., Nausieda, P. A., & Weiner, W. J. (1978) · Neurology · doi:10.1212/wnl.28.10.1064 · Cited by 167
Gilles de la Tourette's Syndrome following Methylphenidate Administration
Golden, G. S. (1974) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1974.tb02715.x · Cited by 148
Central Biogenic Amine Metabolism in Children with the Syndrome of Chronic Multiple Tics of Gilles de la Tourette: Norepinephrine, Serotonin, and Dopamine
Cohen, D. J., Shaywitz, B. A., Young, J. G., Carbonari, C. M., Nathanson, J. A., Lieberman, D., Bowers, M. B., & Maas, J. W. (1979) · Journal of the American Academy of Child Psychiatry · doi:10.1016/s0002-7138(09)61046-3 · Cited by 148
Chronic, Multiple Tics of Gilles de la Tourette's Disease
Cohen, D. J. (1978) · Archives of General Psychiatry · doi:10.1001/archpsyc.1978.01770260123015 · Cited by 146
Dopamine and mania: Behavioral and biochemical effects of the dopamine receptor blocker pimozide
Post, R. M., Jimerson, D. C., Bunney, W. E., & Goodwin, F. K. (1980) · Psychopharmacology · doi:10.1007/bf00431272 · Cited by 136

Show all 28 references

Research works printed but not linked: 3

Meyerhoff JL, 1973, Catecholamine in Gilles de la Tourette's disease: a clinical study with amphetamine isomers, Adv Neurol, 1, 123
Tune LE, 1980, Determination of biogenic amine metabolites in himan lumbar cerebrospinal fluid by HPLC with EC detection, Soc Neurosci Abstr, 6, 108
Van Woert MH, 1976, The Basal Ganglia, 459

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Self-citation
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Self-citation
Nicotine potentiates haloperidol-induced catalepsy and locomotor hypoactivity
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Authors: Singer, H. S., Butler, I. J., Tune, L. E., Seifert, W. E., & Coyle, J. T.
Affiliations: Johns Hopkins University (US)
United States Public Health Service (US)
Corresponding author: Singer, Harvey S.
ORCID: Singer, Harvey S.
Coyle, Joseph T.
Venue: Annals of Neurology
Publisher: Wiley
Published: 1982-10
Volume: 12
Issue: 4
Pages: 361-366
ISSN: 0364-5134 (ISSN-L)
1531-8249
DOI: 10.1002/ana.410120408
OpenAlex: W2011897114
Cited by: 180
References: 28
Citations by year: 2026: 1 · 2025: 2 · 2024: 4 · 2023: 1 · 2022: 3 · 2021: 6 · 2020: 4 · 2019: 6 · 2018: 4 · 2017: 3 · 2016: 6 · 2015: 4 · 2013: 3 · 2012: 7
FWCI: 8.36
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 8042 d)
Locations: Annals of Neurology (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Keywords: Tourette syndrome, haloperidol, dopaminergic dysfunction, homovanillic acid, cerebrospinal fluid, 5-hydroxyindoleacetic acid, antipsychotic treatment response, adverse drug reactions
MeSH terms: Adolescent, Dopamine, Female, Tourette Syndrome, Haloperidol, Homovanillic Acid, Humans, Hydroxyindoleacetic Acid, Male, Methoxyhydroxyphenylglycol, Nervous System Diseases

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