The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides
Open accessAbstract
We have developed an in situ hybridization procedure for the detection of microRNAs (miRNAs) in tissue sections from mouse embryos and adult organs. The method uses highly specific washing conditions for RNA oligonucleotide probes conjugated to a fluorescein hapten. We show that this method detects predominantly mature miRNAs rather than the miRNA precursors or primary transcripts. We have determined expression patterns for several miRNAs expressed in the developing and adult nervous system, including miR‐124a, miR‐9, miR‐92, and miR‐204. Whereas miR‐124a is expressed in neurons, miR‐9 is expressed in neural progenitors and some neurons, and miR‐204 is expressed in the choroid plexus, retinal pigment epithelium, and ciliary body. miR‐204 is located in an intron of the TRPM3 gene, and the TRPM3 mRNA is coexpressed with miR‐204 in the choroid plexus. We also find that primary transcripts for miR‐124a and miR‐9 genes are expressed in patterns similar to their respective mature miRNAs. The ability to visualize expression of specific miRNAs in embryos and tissues should aid studies on miRNA function. Developemental Dynamics 235:2538–2548, 2006. © 2006 Wiley‐Liss, Inc.
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Identification of Novel Genes Coding for Small Expressed RNAs
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miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs
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Regulation of miRNA expression during neural cell specification
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Temporal dynamics and genetic control of transcription in the human prefrontal cortex
Colantuoni, C., Lipska, B. K., Ye, T., Hyde, T. M., Tao, R., Leek, J. T., Colantuoni, E. A., Elkahloun, A. G., Herman, M. M., Weinberger, D. R., et al. (2011) · Nature · doi:10.1038/nature10524 · Cited by 685
The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development
Visvanathan, J., Lee, S., Lee, B., Lee, J. W., & Lee, S.-K. (2007) · Genes & Development · doi:10.1101/gad.1519107 · Cited by 683
The biphasic function of microglia in ischemic stroke
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Metadata
- Authors
- Deo, M., Yu, J., Chung, K., Tippens, M., & Turner, D. L.
- Venue
- Developmental Dynamics
- Publisher
- Wiley
- Published
- 2006-05-30
- Volume
- 235
- Issue
- 9
- Pages
- 2538-2548
- ISSN
- 1058-8388 (ISSN-L)
- 1097-0177
- OpenAlex
- W2154909423
- Cited by
- 282
- References
- 12
- FWCI
- 5.49
- Type
- journal article
- Language
- en
- Open access
- bronze
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