Anhedonia in eating disorders: A meta-analysis and systematic review
Abstract
OBJECTIVE: Anhedonia, or loss of pleasure, is related to deficits in reward processing across a variety of psychiatric disorders. In light of research suggesting abnormal reward processing in eating disorders (EDs), the study of anhedonia in EDs may yield important insights into the role of reward in eating pathology. This meta-analysis and review aimed to provide both a quantitative and qualitative synthesis of the existing literature on this topic. METHOD: We conducted this research (or these meta-analyses) according to PRISMA guidelines. We searched four databases for both peer-reviewed and unpublished literature, and included studies only if a self-report or clinical interview measure of anhedonia was administered to a sample with an ED diagnosis. RESULTS: We included 21 studies in the systematic review, and 10 studies in two meta-analyses that compared anhedonia between ED and control samples (n = 9 studies) and within different ED diagnoses (n = 5 studies). Meta-analyses revealed that anhedonia was significantly higher in ED groups compared to healthy controls, but there was no significant difference in anhedonia between ED diagnostic groups. A qualitative review of the literature also suggested that anhedonia may be correlated with increased ED symptom severity. DISCUSSION: Findings indicated that anhedonia is elevated in EDs and may be a relevant treatment target. Future research should examine how self-reported anhedonia may correlate with components of reward processing in EDs in order to improve theoretical models as well as targeted interventions.
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Research has documented extensive cognitive impairments associated with malnutrition in anorexia nervosa, including brain atrophy, cognitive distortions, reduced executive functioning, and emotional processing issues.
“This raises profound concerns, given that research has documented extensive cognitive impairments associated with malnutrition in anorexia nervosa, including brain atrophy, cognitive distortions, reduced executive functioning, and emotional processing issues (151–155).”
From Assisted death in eating disorders: a systematic review of cases and clinical rationales (2024) · cites this paper as [153]
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Noninvasive transcranial brain stimulation to treat cognitive aspects of other psychiatric diseases
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- Authors
- Dolan, S. C., Khindri, R., Franko, D. L., Thomas, J. J., Reilly, E. E., & Eddy, K. T.
- Affiliations
- Hofstra University (US)
- Northeastern University (US)
- Harvard University (US)
- Corresponding author
- Dolan, Sarah C.
- Venue
- International Journal of Eating Disorders
- Publisher
- Wiley
- Published
- 2021-11-22
- Volume
- 55
- Issue
- 2
- Pages
- 161-175
- ISSN
- 0276-3478 (ISSN-L)
- 1098-108X
- OpenAlex
- W3214990766
- Cited by
- 47
- References
- 61
- Citations by year
- 2026: 8 · 2025: 11 · 2024: 12 · 2023: 7 · 2022: 9
- FWCI
- 0.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Eating Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- anhedonia, eating disorders, reward processing, loss of pleasure, eating pathology, symptom severity, treatment goals
- MeSH terms
- Anorexia Nervosa, Feeding and Eating Disorders, Humans, Reward, Self Report, Anhedonia
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