Risk Assessment of Per- and Polyfluoroalkyl Substance Mixtures: A Relative Potency Factor Approach

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Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) during pregnancy in the Sprague-Dawley rat

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Grouping of PFAS for human health risk assessment: Findings from an independent panel of experts

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Dietary exposure to per- and polyfluoroalkyl substances: Potential health impacts on human liver

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Risks of per- and polyfluoroalkyl substance exposure through marine fish consumption

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Combined Exposure to Multiple Mycotoxins: An Example of Using a Tiered Approach in a Mixture Risk Assessment

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New approach methodologies: A quantitative in vitro to in vivo extrapolation case study with PFASs

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Four Decades of Spatiotemporal Variability of Per- and Polyfluoroalkyl Substances (PFASs) in the Baltic Sea

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Dioxins vs. PFAS: Science and Policy Challenges

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Critical review on PFOA, kidney cancer, and testicular cancer

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Analysis of per- and polyfluoroalkyl substances in plastic food storage bags by different analytical approaches

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Survival, Growth, and Reproduction Responses in a Three-Generation Exposure of the Zebrafish (Danio rerio) to Perfluorooctane Sulfonate

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Persistent organic pollutants associate with liver disease in a Finnish general population sample

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Determination of in vitro immunotoxic potencies of a series of perfluoralkylsubstances (PFASs) in human Namalwa B lymphocyte and human Jurkat T lymphocyte cells

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Current and emerging issues in chemical food safety

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Legacy and Novel Per- and Polyfluoroalkyl Substances in Tap Water from East China: Impact from Water Sources and Risk Mitigation by Household Purifiers

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Exposure to Per- and Polyfluoroalkyl Substances and Liver Cancer: A Systematic Review of Animal and Epidemiological Studies

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Target determination and suspect screening of legacy and emerging per- and poly-fluoro poly-ethers in wild boar liver, in Italy

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Unregulated and Regulated PFASs in Bottled and Tap Water: Occurrence, Co-Occurrence Patterns, and Implications for Human Health and Regulatory Frameworks

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Association between mixed exposure to per- and polyfluoroalkyl substances and metabolic syndrome in Korean adults: Data from the Korean National environmental health survey cycle 4

Chung, S. M., Kim, K. H., Moon, J. S., & Won, K. C. (2024) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2024.114427 · Cited by 12 · see citing works

The use of canonical dose–response models for benchmark dose analysis of continuous toxicological data

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Cumulative Exposure and Health Risk Assessment of PFAS in Animal-Derived Foods Using the Relative Potency Factor Approach

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Emerging organophosphate ester resorcinol bis(diphenyl phosphate) exerts estrogenic effects via estrogen receptor pathways

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Identification of new PFAS for severe interference with thyroid hormone transport: A combined in vitro/silico approach

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Non-linear associations between exposure to a mixture of per- and polyfluoroalkyl substances and thyroid hormone levels in Korean adults

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Large scale study on PFASs levels in fruits, vegetables and soil from allotments and gardens contaminated by atmospheric deposition from a Dutch fluorochemical production plant

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A multi-tiered hierarchical Bayesian approach to derive toxic equivalency factors for dioxin-like compounds

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Letter to the Editor on Bil et al. 2021 “Risk Assessment of Per- and Polyfluoroalkyl Substance Mixtures: A Relative Potency Factor Approach”

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Commentary: Cumulative Risk Assessment of Perfluoroalkyl Carboxylic Acids and Perfluoralkyl Sulfonic Acids: What Is the Scientific Support for Deriving Tolerable Exposures by Assembling 27 PFAS into 1 Common Assessment Group?

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Oxide-Perovskites for Automotive Catalysts Biotransform and Induce Multicomponent Clearance and Hazard

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Surface soil per- and polyfluoroalkyl substance mixtures dominated by perfluorooctane sulfonate: prioritization for ecotoxicity testing and ecological risk assessment at current and former U.S. Air Force bases

East, A., Anderson, R. H., Duncan, C. M., & Salice, C. J. (2025) · Environmental Toxicology and Chemistry · doi:10.1093/etojnl/vgaf001 · Cited by 9 · see citing works

Structure-specific variation in per- and polyfluoroalkyl substances toxicity among genetically diverse Caenorhabditis elegans strains

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Decorative cosmetics and skin care products contribute significantly to short-chain perfluoroalkyl carboxylates exposure

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Efficient removal of PFAS in groundwater and landfill leachate using iron-modified peat residues and electrochemical oxidation

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Per- and polyfluoroalkyl mixtures toxicity assessment “Proof-of-Concept” illustration for the hazard index approach

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Response to Letter to the Editor on Bil et al. 2021 “Risk Assessment of Per- and Polyfluoroalkyl Substance Mixtures: A Relative Potency Factor Approach”

Bil, W., Zeilmaker, M. J., Fragki, S., Lijzen, J. P. A., Verbruggen, E. M. J., & Bokkers, B. G. H. (2021) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5236 · Cited by 9 · see citing works

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Exposure to a GenX Homologue Results in Sexually Dimorphic Bile Acid Metabolism Disorders Mediated by Hepatic PPARα in Mice

Ren, W., Dong, F., Wang, Z., Guo, Y., Sheng, N., & Dai, J. (2025) · Environmental Science & Technology · doi:10.1021/acs.est.5c08503 · Cited by 9 · see citing works

A harmonized Danube basin-wide multi-compartment concentration database to support inventories of micropollutant emissions to surface waters

Kittlaus, S., Kardos, M. K., Dudás, K. M., Weber, N., Clement, A., Petkova, S., Šuković, D., Grgić, D. K., Kovács, Á., Kocman, D., et al. (2024) · Environmental Sciences Europe · doi:10.1186/s12302-024-00862-4 · Cited by 8 · see citing works

A novel approach to assess the health risk of aryl hydrocarbon receptor-bound contaminants via inhalation exposure using CYP1A1 expression as a biomarker

Zhong, H., Yu, L., Lv, X., Yu, Y., & Hu, J. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116466 · Cited by 8 · see citing works

PFAS drinking water treatment trade-offs: comparing the health burden of GAC treatment to the health benefits of reduced PFAS exposure

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Methodological Approaches for Risk Assessment of Tobacco and Related Products

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Leaching profile of per- and polyfluoroalkyl substances from selected e-waste components and potential exposure pathways from discarded components

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Per- and polyfluoroalkyl substances (PFAS) in drinking water systems in the lower Yangtze River: source, fate, and health risk assessment

Yuan, H., Ding, Q., Yang, T., Li, X., Song, N., & Zhang, J. (2025) · Environmental Geochemistry and Health · doi:10.1007/s10653-025-02506-9 · Cited by 7 · see citing works

Comparison of four PFAS mixtures assessment approaches based on extensive tap water and groundwater data

Scaggiante, G., Zingaretti, D., & Verginelli, I. (2025) · Environmental Pollution · doi:10.1016/j.envpol.2025.127177 · Cited by 8 · see citing works

Issues in the hazard and risk assessment of perfluoroalkyl substance mixtures

Colnot, T., & Dekant, W. (2021) · Toxicology Letters · doi:10.1016/j.toxlet.2021.10.005 · Cited by 7 · see citing works

PFAS and One Health: integrating human, animal, and environmental perspectives

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Target and non-target screening of per- and polyfluoroalkyl substances (PFAS) in drinking water: Focus on alternatives and health risks

Shao, G., Jiang, N., Liu, T., You, X., Liu, R., Zhang, P., & Wang, Y. (2025) · Environmental Research · doi:10.1016/j.envres.2025.122581 · Cited by 6 · see citing works

Dose Addition Models Accurately Predict the Subacute Effects of a Mixture of Perfluorooctane Sulfonate and Perfluorooctanoic Acid on Japanese Quail (Coturnix japonica) Chick Mortality

Gray, L. E., Conley, J. M., & Bursian, S. J. (2023) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5758 · Cited by 6 · see citing works

High-Resolution Mass Spectrometry for Identification, Quantification, and Risk Assessment of 40 PFAS Migrating from Microwave Popcorn Bags

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Characterisation of the risk associated with chronic lifetime exposure to mixture of chemical hazards: case study of trace elements

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Implications of grouping per‐ and polyfluoroalkyl substances for contaminated site regulation

Bowles, K. C., Anderson, J. K., Anderson, R. H., Bani, B., Barnes, C. M., Brusseau, M. L., Cousins, I. T., Cushing, P., DiGuiseppi, B., Gray, B., et al. (2024) · Remediation Journal · doi:10.1002/rem.21783 · Cited by 5 · see citing works

First Report on the Tissue Distributions and Habitat Differences of PFMOAA and Other PFAS in Veined Rapa Whelk ( Rapana venosa )

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Receptor-specific inhibition of pro-inflammatory cytokine secretion induced by PFAS in THP1-derived macrophages: a structure-activity relationship study

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Quantifying the Trophic Transfer Process and Dietary Source of Legacy and Emerging Per- and Polyfluoroalkyl Substances in the Food Web in Bohai Sea

Li, F., Zhou, S., Han, D., Guo, H., Huang, K. J., Yang, T., Yang, L., Yao, L., Ren, Z., Chen, L., et al. (2026) · Environmental Science & Technology · doi:10.1021/acs.est.6c00335 · Cited by 3 · see citing works

PFAS contaminants in surface waters, effluents, sediments and coastal food webs off the Solent coastline UK

Obanya, H. E., Ginley, F., Payne, M. R., & Ford, A. T. (2026) · Marine Environmental Research · doi:10.1016/j.marenvres.2026.108094 · Cited by 3 · see citing works

Effects of Perfluorohexane Sulfonate Exposure on Immune Cell Populations in Naive Mice

Pierpont, T. M., Elmore, J. P., Redko, A., Anannya, O., Imbiakha, B., O’Hare, K., Villanueva, A., Anronikov, S., Bondah, N., Chang, S., et al. (2024) · ImmunoHorizons · doi:10.4049/immunohorizons.2300049 · Cited by 3 · see citing works

Internal Relative Potency Factors for the Risk Assessment of Mixtures of Per- and Polyfluoroalkyl Substances (PFAS) in Human Biomonitoring

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Mixture exposure to PFAS: A Relative Potency Factor approach

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Nationwide Monitoring and Hepatic Mixture Risk Assessment of PFASs in Korean Drinking Water Using Relative Potency Factors

Kim, Y. H., Hashemi, S., Pyo, H., Lim, Y. W., Kim, C., Choi, I., & 양지연 (2026) · Toxics · doi:10.3390/toxics14070577

S16-03 Recent advances in the risk assessment methodology for PFAS mixtures: Derivation of relative potency factors (RPFs) for PFAS

Bil, W., Zeilmaker, M. J., Verbruggen, E. M. J., & Bokkers, B. G. H. (2024) · Toxicology Letters · doi:10.1016/j.toxlet.2024.07.101

Risk Assessment of Per- and Polyfluoroalkyl Substances (PFASs) Mixtures: A Relative Potency Factor Approach.

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