Clinicopathological correlates of depression in early Alzheimer's disease in the NACC
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Objective: Depression may be a prodrome to Alzheimer's disease (AD). We assessed whether AD neuropathology is associated with depression in mild cognitive impairment (MCI) and mild dementia (dAD). Methods: All clinical and neuropathological data for this study came from the National Alzheimer's Coordinating Center (NACC). Healthy control (HC, n = 120), MCI (n = 77), and mild dAD (n = 93) patients who underwent brain autopsy were included. In regression models with Geriatric Depression Scale (GDS) as the outcome, neuritic plaque (NP) score or Braak Stages of neurofibrillary (NF) pathology were covariates. Results: GDS was not associated with cognitive status, NP score, Braak Stages, or their interaction. In both models, a history of TIAs, depression within the last 2 years, current benzodiazepine use, and greater severity of neuropsychiatric symptoms were associated with greater depression. In the Braak Stages model, less education was another significant predictor. Conclusions: Depression in early AD appears to be independent of NP and NF pathology. Studies are needed to investigate other mechanisms that may be responsible for depression in MCI and dAD.
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Another neuropathology study found no significant association between depressive symptoms cognitive status, neuritic plaque, and neurofibrillary tangle scores or their interactions.
“Another neuropathology study found no significant association between depressive symptoms cognitive status, neuritic plaque, and neurofibrillary tangle scores or their interactions124.”
From Mechanisms and treatment of late-life depression (2019) · cites this paper as [124]
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Cites
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282 · see citing works
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915 · see citing works
Hirono, N., Mori, E., Ikejiri, Y., Imamura, T., Shimomura, T., Hashimoto, M., Yamashita, H., & Ikeda, M. (1997) · PubMed · Cited by 21,010 · see citing works
Kok, J. S., Berg, I. J., & Scherder, E. J. A. (2013) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000353441 · Cited by 20,589 · see citing works
Older Adults' Reasons for Using Technology while Aging in Place
Peek, S. T. M., Luijkx, K. G., Rijnaard, M. D., Nieboer, M. E., van der Voort, C. S., Aarts, S., van Hoof, J., Vrijhoef, H. J., & Wouters, E. (2015) · Gerontology · doi:10.1159/000430949 · Cited by 19,803 · see citing works
Sensitivity and False Alarm Rate of a Fall Sensor in Long-Term Fall Detection in the Elderly
Kangas, M., Korpelainen, R., Vikman, I., Nyberg, L., & Jämsä, T. J. (2014) · Gerontology · doi:10.1159/000362720 · Cited by 19,003 · see citing works
Neuropathological stageing of Alzheimer-related changes.
Braak, H., & Braak, E. (1991) · Acta Neuropathologica · doi:10.1007/bf00308809 · Cited by 16,123 · cited 4× · see citing works
“…to Consortium to Establish A Registry for Alzheimer’s Disease (CERAD) standards (Mirra et al., 1991); Braak and Braak Neurofibrillary Stages (Braak and Braak, 1991); the presence of non-AD neuropathologies such as Lewy body pathology, hippocampal sclerosis, frontotemporal dementia, prion…”
BackgroundInfluentialMild cognitive impairment as a diagnostic entity
Petersen, R. C. (2004) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01388.x · Cited by 7,864 · see citing works
The Neuropsychiatric Inventory: Comprehensive assessment of psychopathology in dementia
Cummings, J. L., Mega, M., Gray, K., Rosenberg-Thompson, S., Carusi, D. A., & Gornbein, J. (1994) · Neurology · doi:10.1212/wnl.44.12.2308 · Cited by 7,568 · see citing works
A New Clinical Scale for the Staging of Dementia
Hughes, C. P., Berg, L., Danziger, W., Coben, L. A., & Martin, R. L. (1982) · British Journal of Psychiatry · doi:10.1192/bjp.140.6.566 · Cited by 7,056 · see citing works
Mirra, S. S., Heyman, A., McKeel, D., Sumi, S. M., Crain, B. J., Brownlee, L. M., Vogel, F. S., Hughes, J. P., Belle, G. V., Berg, L., et al. (1991) · Neurology · doi:10.1212/wnl.41.4.479 · Cited by 4,961 · see citing works
Hyman, B. T., Phelps, C. H., Beach, T. G., Bigio, E. H., Cairns, N. J., Carrillo, M. C., Dickson, D. W., Duyckaerts, C., Frosch, M. P., Masliah, E., et al. (2012) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.10.007 · Cited by 3,092 · see citing works
Diniz, B. S., Butters, M. A., Albert, S. M., Dew, M. A., & Reynolds, C. F. (2013) · British Journal of Psychiatry · doi:10.1192/bjp.bp.112.118307 · Cited by 1,290 · see citing works
Pathological verification of ischemic score in differentiation of dementias
Rosen, W. G., Terry, R. D., Fuld, P. A., Katzman, R., & Peck, A. (1980) · Annals of Neurology · doi:10.1002/ana.410070516 · Cited by 1,273 · see citing works
Morris, J. C., Weintraub, S., Chui, H. C., Cummings, J., DeCarli, C., Ferris, S., Foster, N. L., Galasko, D., Graff-Radford, N., Peskind, E. R., et al. (2006) · Alzheimer Disease & Associated Disorders · doi:10.1097/01.wad.0000213865.09806.92 · Cited by 950 · see citing works
The vascular depression hypothesis: mechanisms linking vascular disease with depression
Taylor, W. D., Aizenstein, H. J., & Alexopoulos, G. S. (2013) · Molecular Psychiatry · doi:10.1038/mp.2013.20 · Cited by 923 · see citing works
Staging Dementia Using Clinical Dementia Rating Scale Sum of Boxes Scores
O’Bryant, S. E. (2008) · Archives of Neurology · doi:10.1001/archneur.65.8.1091 · Cited by 885 · see citing works
Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease
(1990) · American Journal of Psychiatry · doi:10.1176/ajp.147.8.1049 · Cited by 744 · see citing works
Modrego, P. J., & Ferrández, J. (2004) · Archives of Neurology · doi:10.1001/archneur.61.8.1290 · Cited by 539 · see citing works
Banerjee, S., Hellier, J., Dewey, M., Romeo, R., Ballard, C., Baldwin, R., Bentham, P., Fox, C., Holmes, C., Katona, C., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60830-1 · Cited by 532 · see citing works
Barnes, D. E., Alexopoulos, G. S., Lopez, O. L., Williamson, J. D., & Yaffe, K. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.3.273 · Cited by 465 · see citing works
Midlife vs Late-Life Depressive Symptoms and Risk of Dementia
Yaffe, K. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.1481 · Cited by 449 · see citing works
Depression in Alzheimer’s disease: overview and treatment
Lyketsos, C. G., & Olin, J. T. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01348-3 · Cited by 393 · see citing works
Self-citationIntroduction to multivariate regression analysis.
Alexopoulos, E. C. (2010) · Europe PMC (PubMed Central) · Cited by 366 · see citing works
The association of neuropsychiatric symptoms in MCI with incident dementia and Alzheimer disease
Rosenberg, P. B., Mielke, M. M., Appleby, B. S., Oh, E. S., Geda, Y. E., & Lyketsos, C. G. (2013) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2013.01.006 · Cited by 366 · see citing works
Self-citationThe National Alzheimer's Coordinating Center (NACC) Database: an Alzheimer disease database.
Beekly, D. L., Ramos, E. M., van Belle, G., Deitrich, W. D., Clark, A. D., Jacka, M. E., & Kukull, W. A. (2004) · PubMed · Cited by 345 · see citing works
Sertraline for the treatment of depression in Alzheimer disease
Rosenberg, P. B., Martin, B. K., Frangakis, C., Mintzer, J. E., Weintraub, D., Porsteinsson, A. P., Schneider, L. S., Rabins, P. V., Munro, C. A., Meinert, C. L., et al. (2010) · The American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3181c796eb · Cited by 250 · see citing works
Self-citationNeuron loss in key cholinergic and aminergic nuclei in Alzheimer disease: a meta-analysis
Lyness, S. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00057-x · Cited by 240 · see citing works
Liu, Y., Yoo, M.-J., Savonenko, A., Stirling, W., Price, D. L., Borchelt, D. R., Mamounas, L., Lyons, W. E., Blue, M. E., & Lee, M. K. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4218-08.2008 · Cited by 206 · see citing works
Frontal lobe hypometabolism and depression in Alzheimer's disease
Hirono, N., Mori, E., Ishii, K., Ikejiri, Y., Imamura, T., Shimomura, T., Hashimoto, M., Yamashita, H., & Sasaki, M. (1998) · Neurology · doi:10.1212/wnl.50.2.380 · Cited by 189 · see citing works
Steenland, K., Karnes, C., Seals, R. M., Carnevale, C. V., Hermida, A. P., & Levey, A. I. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-111922 · Cited by 188 · see citing works
Increased Neurofibrillary Tangles in Patients With Alzheimer Disease With Comorbid Depression
Rapp, M. A., Beeri, M. S., Purohit, D. P., Perl, D. P., Haroutunian, V. H., & Sano, M. C. (2008) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31816029ec · Cited by 178 · see citing works
Lee, G. J., Lu, P. H., Hua, X., Lee, S., Wu, S., Nguyen, K., Teng, E., Leow, A., Jack, C. R., Toga, A. W., et al. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.12.024 · Cited by 172 · see citing works
Overlap between neurodegenerative disorders
Armstrong, R. A., Lantos, P. L., & Cairns, N. J. (2005) · Neuropathology · doi:10.1111/j.1440-1789.2005.00605.x · Cited by 146 · see citing works
Imaging Alzheimer Pathology in Late-Life Depression With PET and Pittsburgh Compound-B
Butters, M. A., Klunk, W. E., Mathis, C. A., Price, J. C., Ziolko, S. K., Hoge, J. A., Tsopelas, N. D., Lopresti, B. J., Reynolds, C. F., DeKosky, S. T., et al. (2008) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0b013e31816c92bf · Cited by 139 · see citing works
Iulio, F. D., Palmer, K., Blundo, C., Casini, A. R., Gianni, W., Caltagirone, C., & Spalletta, G. (2010) · International Psychogeriatrics · doi:10.1017/s1041610210000281 · Cited by 136 · see citing works
Rosenberg, P. B., Mielke, M. M., Han, D., Leoutsakos, J., Lyketsos, C. G., Rabins, P. V., Zandi, P. P., Breitner, J. C. S., Norton, M. C., Welsh-Bohmer, K. A., et al. (2012) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.3769 · Cited by 117 · see citing works
Self-citationDepressive symptoms, clinical AD, and cortical plaques and tangles in older persons
Wilson, R. S., Schneider, J. A., Bienias, J. L., Arnold, S. E., Evans, D. A., & Bennett, D. A. (2003) · Neurology · doi:10.1212/01.wnl.0000092914.04345.97 · Cited by 109 · see citing works
Neuropathologic Correlates of Late-Onset Major Depression
Sweet, R. A., Hamilton, R. L., Butters, M. A., Mulsant, B. H., Pollock, B. G., Lewis, D. A., López, O. L., DeKosky, S. T., & Reynolds, C. F. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300554 · Cited by 105 · see citing works
Tighe, S. K., Oishi, K., Mori, S., Smith, G. S., Albert, M., Lyketsos, C. G., & Mielke, M. M. (2012) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/appi.neuropsych.11120375 · Cited by 77 · see citing works
Self-citationZahodne, L. B., Gongvatana, A., Cohen, R. A., Ott, B. R., & Tremont, G. (2013) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2013.01.043 · Cited by 72 · see citing works
Anterior cingulate dysfunction in geriatric depression
Alexopoulos, G. S., Gunning‐Dixon, F. M., Latoussakis, V., Kanellopoulos, D., & Murphy, C. F. (2007) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1939 · Cited by 71 · see citing works
Age, Alzheimer's disease and dementia in the Baltimore Longitudinal Study of Ageing
Dolan, D., Troncoso, J., Resnick, S. M., Crain, B. J., Zonderman, A. B., & O'Brien, R. J. (2010) · Brain · doi:10.1093/brain/awq141 · Cited by 70 · see citing works
Self-citationKoliatsos, V. E., Martin, L. J., Walker, L. C., Richardson, R. T., DeLong, M. R., & Price, D. L. (1988) · Brain Research · doi:10.1016/0006-8993(88)90535-5 · Cited by 67 · see citing works
Self-citationHoogendijk, W. J. G., Sommer, I. E., Pool, C. W., Kamphorst, W., Hofman, M. A., Eikelenboom, P., & Swaab, D. F. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.1.45 · Cited by 62 · see citing works
Evolution of Depressive Symptoms in Alzheimer Disease
Garre‐Olmo, J., Pousa, S. L., Franch, J. V., Estrada, A. T., Hernández-Ferràndiz, M., Gallego, M. L., Tibau, C. F., Puig-Vidal, O., Muñoz, V. M., & Cruz-Reina, M. M. (2003) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-200304000-00005 · Cited by 55 · see citing works
Khundakar, A. A., & Thomas, A. J. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-148003 · Cited by 53 · see citing works
O’Brien, J., Thomas, A., Ballard, C., Brown, A., Ferrier, N., Jaros, E., & Perry, R. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00944-6 · Cited by 46 · see citing works
Lewy bodies in the amygdala increase risk for major depression in subjects with Alzheimer disease
López, O. L., Becker, J. T., Sweet, R. A., Martín‐Sánchez, F. J., & Hamilton, R. L. (2006) · Neurology · doi:10.1212/01.wnl.0000230161.28299.3c · Cited by 46 · see citing works
Qiu, W. Q., Zhu, H., Dean, M., Liu, Z., Vu, L., Fan, G., Li, H., Mwamburi, M., Steffens, D. C., & Au, R. (2015) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4339 · Cited by 41 · see citing works
Medial temporal lobe atrophy in Alzheimer's disease/mild cognitive impairment with depression
Dhikav, V., Sethi, M., & Anand, K. S. (2014) · British Journal of Radiology · doi:10.1259/bjr.20140150 · Cited by 40 · see citing works
Quality of life (QoL) in community-dwelling and institutionalized Alzheimer's disease (AD) patients
León‐Salas, B., Olazarán, J., Cruz, I., Agüera-Ortíz, L., Dobato, J. L., Valentí, M., Múñiz, R., González-Salvador, T., & Martínez‐Martín, P. (2013) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2013.04.013 · Cited by 39 · see citing works
Serotoninergic neurites in senile plaques in cingulate cortex of aged nonhuman primate
Kitt, C. A., Walker, L. C., Molliver, M. E., & Price, D. L. (1989) · Synapse · doi:10.1002/syn.890030103 · Cited by 10 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Sheikh JI Yesavage JA Geriatric Depression Scale (GDS): recent evidence and development of a shorter version. Clinical Gerontology: A Guide to Assessment and Intervention 165-173 1986 The Haworth Press NY
Cited by
Sorted by citations
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Alexopoulos, G. S. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0514-6 · Cited by 592 · see citing works
Vascular depression consensus report – a critical update
Aizenstein, H. J., Baskys, A., Boldrini, M., Butters, M. A., Diniz, B. S., Jaiswal, M. K., Jellinger, K. A., Kruglov, L. S., Meshandin, I. A., Mijajlovic, M. D., et al. (2016) · BMC Medicine · doi:10.1186/s12916-016-0720-5 · Cited by 261 · see citing works
Ismail, Z., Gatchel, J., Bateman, D. R., Barcelos-Ferreira, R., Cantillon, M., Jaeger, J., Donovan, N. J., Mortby, M. E., & Mortby, M. E. (2018) · International Psychogeriatrics · doi:10.1017/s1041610217001880 · Cited by 221 · see citing works
Siafarikas, N., Selbæk, G., Fladby, T., Benth, J. Š., Auning, E., & Aarsland, D. (2017) · International Psychogeriatrics · doi:10.1017/s1041610217001879 · Cited by 146 · see citing works
Devanand, D. P., Lee, S., Huey, E. D., & Goldberg, T. E. (2022) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2021.4363 · Cited by 105 · see citing works
Oral function as an indexing parameter for mild cognitive impairment in older adults
Watanabe, Y., Arai, H., Hirano, H., Morishita, S., Ohara, Y., Edahiro, A., Murakami, M., Shimada, H., Kikutani, T., & Suzuki, T. (2018) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.13259 · Cited by 74 · see citing works
The heterogeneity of late-life depression and its pathobiology: a brain network dysfunction disorder
Jellinger, K. A. (2023) · Journal of Neural Transmission · doi:10.1007/s00702-023-02648-z · Cited by 59 · see citing works
Neuropathological correlates of neuropsychiatric symptoms in dementia
Gibson, L. L., Grinberg, L. T., Ffytche, D. H., Leite, R. E. P., Rodriguez, R. D., Ferretti‐Rebustini, R. E. D. L., Pasqualucci, C. A., Nitríni, R., Filho, W. J., Aarsland, D., et al. (2022) · Alzheimer s & Dementia · doi:10.1002/alz.12765 · Cited by 49 · see citing works
Antidepressant-like effect of pramipexole in an inflammatory model of depression
Lieberknecht, V., Cunha, M. P., Junqueira, S. C., Coelho, I. D. S., de Souza, L. F., Santos, A. R. S., Rodrigues, A. L. S., Dutra, R. C., & Dafré, A. L. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.11.007 · Cited by 45 · see citing works
Ebrahim, I., Ghahremani, M., Camicioli, R. M., Smith, E. E., & Ismail, Z. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.03.074 · Cited by 44 · see citing works
Weight Rich-Club Analysis in the White Matter Network of Late-Life Depression with Memory Deficits
Mai, N., Zhong, X., Chen, B., Peng, Q., Wu, Z., Zhang, W., Ouyang, C., & Ning, Y. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00279 · Cited by 40 · see citing works
Schipke, C. G., Vos, A. D., Fuentes, M., Jacobs, D., Vanmechelen, E., & Peters, O. (2018) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000489847 · Cited by 27 · see citing works
The enigma of vascular depression in old age: a critical update
Jellinger, K. A. (2022) · Journal of Neural Transmission · doi:10.1007/s00702-022-02521-5 · Cited by 27 · see citing works
Vinutha, N., Pattar, S., Sharma, S., Shenoy, P. D., & Venugopal, K. R. (2020) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2020.7 · Cited by 25 · see citing works
Wang, S., Kim, N.-Y., Um, Y. H., Kang, D. W., Na, H.-R., Lee, C. U., & Lim, H. K. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01072-9 · Cited by 23 · see citing works
Mechanisms and treatment of late-life depression
Alexopoulos, G. S. (2021) · Focus · doi:10.1176/appi.focus.19304 · Cited by 22 · see citing works
Sinclair, L. I., Mohr, A., Morisaki, M., Edmondson, M., Chan, S., Bone‐Connaughton, A., Turecki, G., & Love, S. (2023) · Alzheimer s Research & Therapy · doi:10.1186/s13195-023-01299-2 · Cited by 23 · see citing works
Leeuwis, A. E., Weaver, N. A., Biesbroek, J. M., Exalto, L. G., Kuijf, H. J., Hooghiemstra, A. M., Prins, N. D., Scheltens, P., Barkhof, F., van der Flier, W. M., et al. (2019) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.180136 · Cited by 18 · see citing works
Brain pathology and cognitive scores prior to onset of late‐life depression
Almdahl, I. S., Agartz, I., Hugdahl, K., Korsnes, M. S., & Initiative, A. D. N. (2022) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5686 · Cited by 16 · see citing works
β-amyloid pathology is not associated with depression in a large community sample autopsy study
Saldanha, N. M., Suemoto, C. K., Rodriguez, R. D., Leite, R. E. P., Nascimento, C. F., Ferretti‐Rebustini, R. E. D. L., da Silva, M. M., Pasqualucci, C. A., Nitríni, R., Filho, W. J., et al. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.09.062 · Cited by 16 · see citing works
Pathological Correlations of Neuropsychiatric Symptoms in Institutionalized People with Dementia
Antonio, E. E., López‐Álvarez, J., Rábano, A., Agüera-Ortíz, L., Sánchez‐Soblechero, A., Amaya, L. J. D., Portela, S., Caramé, C. C., & Olazarán, J. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200600 · Cited by 16 · see citing works
Sinclair, L. I., Ballard, C. G., & Initiative, A. D. N. (2022) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5858 · Cited by 13 · see citing works
The Interface between Depression and Alzheimer’s Disease. A Comprehensive Approach
Modrego, P. J., de Cerio, L. D., & Lobo, A. (2023) · Annals of Indian Academy of Neurology · doi:10.4103/aian.aian_326_23 · Cited by 8 · see citing works
The role of sex differences in depression in pathologically defined Alzheimer’s disease
Tremblay, C., Choudhury, P., Belden, C. M., Goldfarb, D., Lorenzini, I., Beach, T. G., & Serrano, G. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1156764 · Cited by 8 · see citing works
Lin, R., Wei, B., Huang, C., Chen, D., Zhu, Z., Shi, Y., Yan, Y., & Li, H. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.119825 · Cited by 4 · see citing works
Depression and somatic symptoms in dementia: A narrative review
Mukku, S. S. R., Desai, G., & Chaturvedi, S. K. (2020) · Journal of Geriatric Mental Health · doi:10.4103/jgmh.jgmh_4_20 · Cited by 2 · see citing works
Evaluation of Neuropsychological Tests in Classification of Alzheimer’s Disease
Vinutha, N., Jayasudha, R., Inchara, K. S., Khan, H., Sharma, S., Shenoy, P. D., & Venugopal, K. R. (2018) · Advances in intelligent systems and computing · doi:10.1007/978-981-13-0224-4_14 · Cited by 2 · see citing works
Efficient Data Mining Techniques for Handling Neurodegenerative Disorder
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Sinclair, L. I., Morisaki, M., Henley, P. P., Dempster, E. L., Ballard, C. G., Lin, J. T., MacLachlan, R., & Love, S. (2026) · Journal of Alzheimer s Disease Reports · doi:10.1177/25424823261472076
- Authors
- McCutcheon, S. T., Han, D., Troncoso, J., Koliatsos, V. E., Albert, M., Lyketsos, C. G., & Leoutsakos, J. S.
- Affiliations
- University of Iowa (US)
- Johns Hopkins University (US)
- Corresponding author
- McCutcheon, Sarah T.
- Venue
- International Journal of Geriatric Psychiatry
- Publisher
- Wiley
- Published
- 2016-02-14
- Volume
- 31
- Issue
- 12
- Pages
- 1301-1311
- ISSN
- 0885-6230 (ISSN-L)
- 1099-1166
- PMC
- PMC4983531
- OpenAlex
- W2260677129
- Cited by
- 29
- References
- 53
- Citations by year
- 2026: 1 · 2025: 1 · 2023: 5 · 2022: 5 · 2021: 3 · 2020: 4 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 2
- FWCI
- 2.96
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- International Journal of Geriatric Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIA/NIH (U01 AG016976)
- NIA-funded ADCs (P30 AG019610, P30 AG013846, P50 AG008702, P50 AG025688, P30 AG010133, P50 AG005146, P50 AG005134, P50 AG016574, P50 AG005138, P30 AG008051, P30 AG013854, P30 AG008017, P30 AG010161, P30 AG010129, P50 AG016573, P50 AG016570, P50 AG005131, P50 AG023501, P30 AG035982, P30 AG028383, P30 AG010124, P50 AG005133, P50 AG005142, P30 AG012300, P50 AG005136, P50 AG033514, P50 AG005681)
- NIH/NIA (T32 AG027668)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- depression, Alzheimer's disease, mild cognitive impairment, mild dementia, Alzheimer's disease pathology, neuritic plaques, neurofibrillary tangles, Braak stages, Geriatric Depression Scale, neuropsychiatric symptoms, benzodiazepine use, transient ischemic attack, educational attainment, prodromal Alzheimer's disease
- MeSH terms
- Aged, Aged, 80 and over, Alzheimer Disease, Autopsy, Brain, Dementia, Depressive Disorder, Female, Humans, Male, Neuropsychological Tests, Psychiatric Status Rating Scales, Regression Analysis, Case-Control Studies, Plaque, Amyloid, Cognitive Dysfunction
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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