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Psychometric perspectives on diagnostic systems
Open accessAbstract
The author identifies four conceptualizations of the relation between symptoms and disorders as utilized in diagnostic systems such as the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM‐IV; American Psychiatric Association, 1994): A constructivist perspective, which holds that disorders are conveniently grouped sets of symptoms; a diagnostic perspective, which holds that disorders are latent classes underlying the symptoms; a dimensional perspective, which holds that symptoms measure latent continua; and a causal systems perspective, which holds that disorders are causal networks consisting of symptoms and direct causal relations between them. Advantages and disadvantages of these conceptualizations are discussed. The author concludes that the psychometric analysis of diagnostic systems is not settled, and that these systems require deeper psychometric analysis than they currently receive. © 2008 Wiley Periodicals, Inc. J Clin Psychol 64: 1089–1108, 2008.
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“This diversity is not adequately captured by diagnostic disorder categories or the associated disease model, which holds that a given pathology can be explained by a single underlying cause [9].”
From Using person-specific networks in psychotherapy: challenges, limitations, and how we could use them anyway (2020) · cites this paper as [9]
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BackgroundInfluentialMental disorders as networks of problems: a review of recent insights
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van Borkulo, C. D., Borsboom, D., Epskamp, S., Blanken, T. F., Boschloo, L., Schoevers, R. A., & Waldorp, L. (2014) · Scientific Reports · doi:10.1038/srep05918 · Cited by 813
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“Psychiatric diagnoses do not have explanatory power and do not capture the complex causal relationships within and between the genetic, neurophysiological, and behavioral features that characterize mental illness.(13) The overlap in symptoms between diagnoses and the cooccurrence of disorders suggest that there are “n…”
Generalized Network Psychometrics: Combining Network and Latent Variable Models
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InfluentialSelf-citationWhat kinds of things are psychiatric disorders?
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“Whereas the philosophy of biology is the source of the MPC concept, Borsboom (2008) advocates a similar approach to psychiatric disorders from a psychometric perspective.”
BackgroundMental Disorders as Causal Systems: A Network Approach to Posttraumatic Stress Disorder
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“Third, the symptoms of mental disorders frequently violate the axiom of local independence integral to latent variable approaches (Borsboom, 2008; Borsboom et al., 2009).”
BackgroundInfluentialSelf-citationThe Small World of Psychopathology
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“The cause of comorbidity is a puzzle, which may have its roots in the very conceptualization of what a mental disorder is [9,16].”
BackgroundSelf-citationMajor Depression as a Complex Dynamic System
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“In fact, symptoms such as these continue to demonstrate robust associations with one another in adults even in the absence of a major depressive episode (Borsboom, 2008; Santos, Fried, Asafu-Adjei, & Ruiz, 2017).”
BackgroundBrain disorders? Not really: Why network structures block reductionism in psychopathology research
Borsboom, D., Cramer, A. O. J., & Kalis, A. (2019) · Behavioral and Brain Sciences · doi:10.1017/s0140525x17002266 · Cited by 468
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“…but we do object to a latent variable ‘theory’ in which the measurement model with a common cause structure is interpreted as evidence for latent causal entities that operate in the minds of individuals, causing all sorts of cognitive, affective and behavioural patterns (see also Borsboom, 2008b).”
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“According to this model, symptoms of a given disorder are assumed to share an essential property; namely, their causal dependence on a latent variable, from which all symptoms arise (Borsboom, 2008; Kendler et al. 2011).”
BackgroundMethodSelf-citationToward a formalized account of attitudes: The Causal Attitude Network (CAN) model.
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Self-citationA complex network perspective on clinical science
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“That is, the covariance among symptoms must disappear if one conditionalizes on the presence of the disorder (Borsboom, 2008).”
BackgroundA critical evaluation of the complex PTSD literature: Implications for DSM‐5
Resick, P. A., Bovin, M. J., Calloway, A. L., Dick, A. M., King, M. W., Mitchell, K. S., Suvak, M. K., Wells, S. Y., Stirman, S. W., & Wolf, E. J. (2012) · Journal of Traumatic Stress · doi:10.1002/jts.21699 · Cited by 365
“Psychiatric diagnoses are theoretical constructs developed to help understand the co-occurrence of psychiatric symptoms and other psychopathological processes (Borsboom, 2008).”
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“This ‘reflective odel’ is the prevailing perspective with which psychopathology s currently viewed and understood (Borsboom & Cramer, 2013; orsboom, 2008; Cramer, Waldorp, van der Maas, & Borsboom, 010).”
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“This, in turn, implies that symptoms are unlikely to be measurements of one underlying disorder (Borsboom, 2008; Fried, 2015), which is consistent with research documenting that individual depression symptoms differ in important dimensions such as their risk factors (Fried, Nesse, Zivin, Guille, & Sen, 2014; Lux & Ken…”
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“In contrast to both the traditional latent categorical (e.g. Guze, 1992) and latent dimensional (e.g. Helzer et al. 2008) modelsofmentaldisorder, the network perspective does not view symptoms as reflective of an underlying disease entity (Borsboom, 2008; Borsboom & Cramer, 2013).”
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“symptoms to disorder is not one of cause and effect; it is mereological – part(s) to whole (Borsboom, 2008).”
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Frances, A. J., & Widiger, T. (2012) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032511-143102 · Cited by 271
“Our mental disorders are no more than fallible (if undeniably very useful) social constructs (Borsboom 2008, Borsboom et al. 2003, Maddux et al. 2008).”
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“…at Greensboro, Greensboro, NC 27402, USA 2 University of Virginia, Charlottesville, VA, USA attributes proposing that observable variables co-occur because they reciprocally and dynamically reinforce one another, forming a causally connected system (Borsboom, 2008; van der Maas et al., 2006).”
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“Contrary to the diagnostic classification system [44], the goal of this model is to use a data-driven approach to determine constructs that aid in the understanding and classification of mental disorders.”
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“It was originally motivated by work on the theory of psychological measurement (77) and diagnostic systems (78), which described problems with a view of psychiatric disorders (78) or personality dimensions (41) that sees them as arising from a single hidden factor.”
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“Unfortunately, these latent models have serious theoretical and psychometric limitations (Borsboom, 2008).”
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“The classification manuals advanced the field tremendously, but they have also been criticised for their lack of reliability, validity, and clinical utility (e.g., Borsboom, 2008; Lilienfeld, 2014).”
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“Traditional conceptualizations of psychopathology hold that psychiatric disorders are reflected by the assumption that patients’ and cooccurring symptoms have related underlying common causes (Borsboom, 2008; Schmittmann et al., 2013).”
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“Traditional perspectives on psychopathology presumed that some co-occurring symptoms originate from an underlying common cause [60,61].”
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“Also, the proximity of the nodes in the network indicates the closeness of constructs with multiple reciprocal relationships (Epskamp et al., 2012; Borsboom, 2008).”
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“An NM conceptualizes HRQoL as a network of mutually interacting characteristics [28].”
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Self-citationComputational Psychiatry Needs Time and Context
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The Two Disciplines of Scientific Psychology, or: The Disunity of Psychology as a Working Hypothesis
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“According to network theory, a mental disorder is the presentation of interactions between symptoms (Borsboom, 2008; Borsboom & Cramer, 2013).”
BackgroundWhat is the p -factor of psychopathology? Some risks of general factor modeling
van Bork, R., Epskamp, S., Rhemtulla, M., Borsboom, D., & van der Maas, H. L. J. (2017) · Theory & Psychology · doi:10.1177/0959354317737185 · Cited by 131
“The analogy to cognitive systems can be extended to systems of psychopathology as well (Borsboom, 2008; Cramer, Waldorp, van der Maas, & Borsboom, 2010; Schmittmann et al., 2013).”
Self-citationSilvia, P. J., & Christensen, A. P. (2020) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2020.05.013 · Cited by 120
“From this view, the relationship between items and Openness to Experience is mereological: items do not measure Openness to Experience but are part of it [22].”
BackgroundSpiller, T. R., Levi, O., Neria, Y., Suarez‐Jimenez, B., Bar‐Haim, Y., & Lazarov, A. (2020) · BMC Medicine · doi:10.1186/s12916-020-01740-5 · Cited by 127
“In this regard, high hopes were especially put in the concept of node centrality [11], an indicator of the importance of different nodes within a specific network [16].”
BackgroundJunior, H. P. D. O. S., Fried, E. I., Asafu-Adjei, J. K., & Ruiz, R. J. (2017) · Research in Nursing & Health · doi:10.1002/nur.21784 · Cited by 124
“In other words, depressive symptoms co-occur without the need of a latent variable, and can reinforce each other, leading to a depressive state (Borsboom, 2008; Borsboom & Cramer, 2013).”
BackgroundToward an Integrative Psychometric Model of Emotions
Lange, J., Dalege, J., Borsboom, D., Kleef, G. A. V., & Fischer, A. H. (2020) · Perspectives on Psychological Science · doi:10.1177/1745691619895057 · Cited by 124
“They are called the principle of local independence (Borsboom, 2005, 2008; Borsboom et al., 2003) and the assumption of exchangeability (Bollen & Lennox, 1991; Borsboom, 2008; Borsboom et al., 2003).”
InfluentialSelf-citationFrewen, P., Schmittmann, V. D., Bringmann, L. F., & Borsboom, D. (2013) · European Journal of Psychotraumatology · doi:10.3402/ejpt.v4i0.20656 · Cited by 120
“…including all symptoms, utilizing analytic methods associated with Borsboom et al.’s network approach to psychometric theory and comorbidity studies (Borsboom, 2008; Borsboom & Cramer, 2013; Borsboom, Cramer, Schmittmann, Epskamp, & Waldorp, 2011; Cramer, Waldrop, Van der Maas, & Borsboom, 2010;…”
BackgroundMethodInfluentialSelf-citationYoungstrom, E. A. (2012) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2012.736358 · Cited by 115
“…variables, measurement models, or differential item functioning (Guyatt & Rennie, 2002; Straus et al., 2011), despite the fact that these methods are clearly relevant to situations where the ‘‘gold standard’’ criterion diagnosis is missing or flawed (Borsboom, 2008; Kraemer, 1992; Pepe, 2003).”
BackgroundMethodDeconstructing trait anxiety: a network perspective
Heeren, A., Bernstein, E. E., & McNally, R. J. (2018) · Anxiety Stress & Coping · doi:10.1080/10615806.2018.1439263 · Cited by 107
“As Borsboom and colleagues observed (e.g., Borsboom, 2008; Borsboom & Cramer, 2013; Schmittmann et al., 2013), this constitutes a reflective model of the relation between a latent dimension and its indicators (Bollen & Lennox, 1991; Edwards & Bagozzi, 2000) such that trait anxiety presumably causes…”
BackgroundMethodInfluentialMaertens, R., Götz, F. M., Golino, H. F., Roozenbeek, J., Schneider, C. R., Kyrychenko, Y., Kerr, J. R., Stieger, S., McClanahan, W. P., III, Drabot, K., et al. (2023) · Behavior Research Methods · doi:10.3758/s13428-023-02124-2 · Cited by 161
“…gained momentum with the publication of the mutualism model of intelligence (Van Der Maas et al., 2006) and network perspective on psychopathology (Borsboom, 2008; Borsboom et al., 2011; Cramer et al., 2010), giving rise to a new subfield of quantitative psychology called network psychometrics…”
BackgroundHeeren, A., & McNally, R. J. (2017) · Cognitive Therapy and Research · doi:10.1007/s10608-017-9876-3 · Cited by 102
“The network approach to psychopathology (Borsboom 2008, 2017; Borsboom and Cramer 2013) offers a radically new way of understanding SAD.”
BackgroundExtending psychometric network analysis: Empirical evidence against g in favor of mutualism?
Kan, K., van der Maas, H. L. J., & Levine, S. Z. (2019) · Intelligence · doi:10.1016/j.intell.2018.12.004 · Cited by 116
“…(van der Maas et al., 2017), mutualism – the idea of dynamic coupling between cognitive abilities – aligns neatly with some of the latest and most rapid developments in psychometrics, namely psychometric network modeling (Borsboom, 2008; Epskamp, Cramer, Waldorp, Schmittmann, & Borsboom, 2012).”
BackgroundResultInfluentialRouquette, A., Pingault, J., Fried, E. I., Orri, M., Falissard, B., Kossakowski, J. J., Vitaro, F., Tremblay, R. E., Côté, S. M., & Borsboom, D. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.2119 · Cited by 96
Self-citationOn the Control of Psychological Networks
Henry, T. R., Robinaugh, D. J., & Fried, E. I. (2021) · Psychometrika · doi:10.1007/s11336-021-09796-9 · Cited by 105
“Although this common cause model is clearly appropriate for some diseases such as those caused by pathogens, the utility of this perspective for psychopathology has been increasingly questioned (Borsboom 2008; Kendler et al. 2011).”
BackgroundThe Complex Interplay of Pain, Depression, and Anxiety Symptoms in Patients With Chronic Pain
Penedo, J. M. G., Rubel, J. A., Blättler, L. T., Schmidt, S. J., Stewart, J. A., Egloff, N., & Holtforth, M. G. (2019) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000797 · Cited by 103
Network analysis of depressive symptoms in Hong Kong residents during the COVID-19 pandemic
Cheung, T. C. C., Jin, Y., Lam, S. C., Su, Z., Hall, B. J., Xiang, Y., Suen, L. K. P., Chan, S., Ho, H., Lam, H. K. B., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01543-z · Cited by 100
The ontology of posttraumatic stress disorder: Natural kind, social construction, or causal system?
McNally, R. J. (2012) · Clinical Psychology Science and Practice · doi:10.1111/cpsp.12001 · Cited by 94
“The latent variable approach to psychological attributes rests on the axiom of local independence (Borsboom, 2008).”
BackgroundInfluentialSuicide Risk and Protective Factors: A Network Approach
Holman, M., & Williams, M. N. (2020) · Archives of Suicide Research · doi:10.1080/13811118.2020.1774454 · Cited by 113
“While there are numerous measures of centrality, the measurement utilized in this study is strength centrality, which sums the strength of all the edges connected to a node (Epskamp, Maris, Waldorp, & Borsboom, 2018). Bringmann et al. (2019) review the suitability of centrality indices in psychological networks and ar…”
BackgroundMethodInfluentialCoping and resilience in adults: a cross-sectional network analysis
der Hallen, R. V., Jongerling, J., & Godor, B. P. (2020) · Anxiety Stress & Coping · doi:10.1080/10615806.2020.1772969 · Cited by 117
“First, network analysis allows one to unravel complex psychological phenomena through a bottom-up analysis of the different symptoms or behaviors and their associations with each other (Borsboom, 2008; Cramer et al., 2010).”
BackgroundThree representations of the Ising model
Kruis, J., & Maris, G. (2016) · Scientific Reports · doi:10.1038/srep34175 · Cited by 108
“It can quickly be verified that the resulting expression in equation (12) is identical to the distribution for the Curie-Weiss model introduced in equation (3), with the same normalising constant as given in equation (4).”
MethodClassification and psychopathology research.
Berenbaum, H. (2013) · Journal of Abnormal Psychology · doi:10.1037/a0033096 · Cited by 92
Cai, Y., Dong, S., Yuan, S., & Chuan-Peng, H. (2019) · Advances in Psychological Science · doi:10.3724/sp.j.1042.2020.00178 · Cited by 88
“…10 年 来, 网络分析的方法已在人格心理学、社会心理学和临床心理学等领域得到一定的应用。未来研究应继续发 展和完善网络分析模型的理论和方法, 使之运用到更多的数据类型和更广的研究领域中。 关键词 网络分析; 潜变量模型; 心理测量; 临床心理学; 人格特质 分类号 B841 1 引言 准确地描述和解释人类心理与行为是科学心 理学的主要目标之一。在过去几十年中, 研究者 采用潜变量模型(latent variables model) 1来描述和 测量人类心理与行为并取得了丰硕的成果。例如, 人 格 心 理 学 中 的 大 五 人 格 模 型…”
Autism Biomarkers: Challenges, Pitfalls and Possibilities
Anderson, G. M. (2014) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-014-2225-4 · Cited by 86
“fundamentally categorical approaches, seeing the categories merely to represent groups of individuals who are relatively similar phenotypically (Borsboom 2008; Volkmar et al. 2014).”
BackgroundA Call for, and Beginner’s Guide to, Measurement Invariance Testing in Evolutionary Psychology
Wang, S., Chen, C., Dai, C., & Richardson, G. B. (2017) · Evolutionary Psychological Science · doi:10.1007/s40806-017-0125-5 · Cited by 89
Liu, R., Xu, C., Qi, H., Feng, Y., Su, Z., Cheung, T. C. C., Jackson, T., Lei, H., Zhang, L., & Xiang, Y. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.12.137 · Cited by 90
“In traditional approaches to understanding the psychopathology of depression and anxiety, symptoms are secondary to an underlying common cause (Borsboom, 2008; Schmittmann et al., 2013).”
Clarifying the Consensus Definition of Validity
Newton, P. E. (2012) · Measurement Interdisciplinary Research and Perspectives · doi:10.1080/15366367.2012.669666 · Cited by 82
“Borsboom (2008) faced exactly this challenge when discussing the relation between symptoms and mental disorders in clinical settings, concluding that the relationship between certain disorders and their symptoms was not one of measurement but of mereology.”
BackgroundReanalysing the factor structure of the moral foundations questionnaire
Harper, C. A., & Rhodes, D. (2021) · British Journal of Social Psychology · doi:10.1111/bjso.12452 · Cited by 87
“…have recently gained popularity in survey design as an alternative to confirmatory and exploratory factor analyses (e.g., van Borkulo et al., 2015; Borsboom, 2008; Boschloo, van Borkulo, Borsboom, & Schoevers, 2016; Cramer, Waldorp, van der Maas, & Borsboom, 2010; van der Maas et al., 2006;…”
MethodBlasco‐Belled, A., & Alsinet, C. (2022) · Scandinavian Journal of Psychology · doi:10.1111/sjop.12795 · Cited by 95
A decennial review of psychotraumatology: what did we learn and where are we going?
Olff, M., Amstadter, A. B., Armour, C., Birkeland, M. S., Bui, É., Cloître, M., Ehlers, A., Ford, J. D., Greene, T., Hansen, M., et al. (2019) · European Journal of Psychotraumatology · doi:10.1080/20008198.2019.1672948 · Cited by 89
“(Borsboom, 2008; Borsboom, Cramer, Schmittmann, Epskamp, & Waldorp, 2011), in part, reflecting a general rise in complex systems research across many disciplines.”
BackgroundAlves, C. L., Pineda, A. M., Roster, K. I. O., Thielemann, C., & Rodrigues, F. A. (2022) · Journal of Physics Complexity · doi:10.1088/2632-072x/ac5f8d · Cited by 82
“RF -max_depth: the maximum depth of the tree [1, 2, 5, 10, 20, 80] -max_features: the number of features to consider when looking for the best split [2, 3, 5, 10] -min_samples_leaf: the minimum number of samples required to be at a leaf node [1, 2, 3, 4, 5] -min_samples_split: the minimum number of samples required to…”
BackgroundMethodThe Complex Interplay of Pain, Depression, and Anxiety Symptoms in Patients with Chronic Pain
Gomez Penedo, J. M., Rubel, J. A., Blättler, L. T., Schmidt, S. J., Stewart, J. A., Egloff, N., & Holtforth, M. G. (2020) · Bern Open Repository and Information System (University of Bern) · doi:10.7892/boris.138276 · Cited by 75
Network analysis of PTSD and depressive symptoms in 158,139 treatment‐seeking veterans with PTSD
Duek, O., Spiller, T. R., Pietrzak, R. H., Fried, E. I., & Harpaz‐Rotem, I. (2021) · Depression and Anxiety · doi:10.1002/da.23112 · Cited by 71
“In recent years, a new framework for analyzing and understanding psychopathology was introduced; the network approach (Armour et al., 2017; Borsboom, 2008; Fried et al., 2016; McNally, 2016).”
BackgroundInfluentialvan Rentergem, J. A. A., de Vent, N. R., Schmand, B. A., Murre, J. M. J., Staaks, J. P. C., & Huizenga, H. M. (2020) · Neuropsychology Review · doi:10.1007/s11065-019-09423-6 · Cited by 79
“Therefore, there is some-thing to be said for calculating such a composite score, from a constructivist perspective (Borsboom, 2008).”
BackgroundHebbrecht, K., Stuivenga, M., Birkenhäger, T., Morrens, M., Fried, E. I., Sabbe, B., & Giltay, E. J. (2020) · BMC Medicine · doi:10.1186/s12916-020-01867-5 · Cited by 72
“The dominant explanation in the field has been that these relations stem from a shared causal origin, a perspective termed the common cause framework [1, 2].”
BackgroundNetwork analysis of multivariate data in psychological science
(2021) · Nature Reviews Methods Primers · doi:10.1038/s43586-021-00060-z · Cited by 84
Network of depression and anxiety symptoms in patients with epilepsy
Wei, Z., Ren, L., Wang, X., Liu, C., Cao, M., Mengmeng, H., Jiang, Z., Hui, B., Feng, X., Yang, Q., et al. (2021) · Epilepsy Research · doi:10.1016/j.eplepsyres.2021.106696 · Cited by 69
von Klipstein, L., Riese, H., van der Veen, D. C., Servaas, M. N., & Schoevers, R. A. (2020) · BMC Medicine · doi:10.1186/s12916-020-01818-0 · Cited by 63
“sity is not adequately captured by diagnostic disorder categories or the associated disease model, which holds that a given pathology can be explained by a single underlying cause [9].”
BackgroundGolino, H. F., Christensen, A. P., Moulder, R. G., Jr., Kim, S., & Boker, S. M. (2021) · Psychometrika · doi:10.1007/s11336-021-09820-y · Cited by 70
“…of the mutualism model of intelligence (Van Der Maas et al., 2006) and the proposition of the network perspective of psychopathological constructs (Borsboom, 2008; Borsboom & Cramer, 2013; Cramer, Waldorp, Van Der Maas, & Borsboom, 2010; Fried et al., 2017) as well as being employed in clinical…”
BackgroundNetworks and Nosology in Posttraumatic Stress Disorder
McNally, R. J. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.3344 · Cited by 65
Metadata
- Authors
- Borsboom, D.
- Affiliations
- University of Amsterdam (NL)
- Corresponding author
- Borsboom, Denny
- ORCID
- Borsboom, Denny
- Venue
- Journal of Clinical Psychology
- Publisher
- Wiley
- Published
- 2008-08-06
- Volume
- 64
- Issue
- 9
- Pages
- 1089-1108
- ISSN
- 0021-9762 (ISSN-L)
- 1097-4679
- OpenAlex
- W2064794182
- Cited by
- 691
- References
- 48
- Citations by year
- 2026: 53 · 2025: 72 · 2024: 82 · 2023: 82 · 2022: 62 · 2021: 73 · 2020: 67 · 2019: 40 · 2018: 33 · 2017: 27 · 2016: 27 · 2015: 14 · 2014: 11 · 2013: 14 · 2012: 15
- FWCI
- 8.06
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Psychology (publishedVersion)
- PubMed (publishedVersion)
- UvA-DARE (University of Amsterdam) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek (451-03-068)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- diagnostic systems, DSM-IV, constructivist approach, latent class models, dimensional models, causal systems, psychiatric classification
- MeSH terms
- Mental Disorders, Humans, Psychological Theory, Psychometrics, Psychopathology
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