The DOI matches its Crossref record; 265 of the 265 references it cites were found in a registry or an index.
Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
Open accessAbstract
Urine is commonly used for clinical diagnosis and biomedical research. The discovery of extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last decade urinary extracellular vesicles (uEVs) were shown to mirror molecular processes as well as physiological and pathological conditions in kidney, urothelial and prostate tissue. Therefore, several methods to isolate and characterize uEVs have been developed. However, methodological aspects of EV separation and analysis, including normalization of results, need further optimization and standardization to foster scientific advances in uEV research and a subsequent successful translation into clinical practice. This position paper is written by the Urine Task Force of the Rigor and Standardization Subcommittee of ISEV consisting of nephrologists, urologists, cardiologists and biologists with active experience in uEV research. Our aim is to present the state of the art and identify challenges and gaps in current uEV‐based analyses for clinical applications. Finally, recommendations for improved rigor, reproducibility and interoperability in uEV research are provided in order to facilitate advances in the field.
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Self-citationThe biology , function , and biomedical applications of exosomes
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Shedding light on the cell biology of extracellular vesicles
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Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
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Self-citationIdentification and proteomic profiling of exosomes in human urine
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Cited by
Welsh, J. A., Goberdhan, D. C. I., O'Driscoll, L., Buzas, E. I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T. A. P., Erdbrügger, U., et al. (2024) · Journal of Extracellular Vesicles · doi:10.1002/jev2.12404 · Cited by 4,663
Self-citationRamirez-Garrastacho, M., Bajo-Santos, C., Line, A., Martens-Uzunova, E. S., de la Fuente, J. M., Moros, M., Soekmadji, C., Tasken, K. A., & Llorente, A. (2022) · British Journal of Cancer · doi:10.1038/s41416-021-01610-8 · Cited by 130
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Metadata
- Authors
- Erdbrügger, U., Blijdorp, C. J., Bijnsdorp, I. V., Borràs, F. E., Burger, D., Bussolati, B., Byrd, J. B., Clayton, A., Dear, J. W., Falcón‐Pérez, J. M., Grange, C., Hill, A. F., Holthöfer, H., Hoorn, E. J., Jenster, G., Jimenez, C. R., Junker, K., Klein, J., Knepper, M. A., Koritzinsky, E. H., Luther, J. M., Lenassi, M., Leivo, J., Mertens, I., Musante, L., Oeyen, E., Puhka, M., van Royen, M. E., Sánchez, C., Soekmadji, C., Thongboonkerd, V., van Steijn, V., Verhaegh, G., Webber, J. P., Witwer, K., Yuen, P. S. T., Zheng, L., Llorente, A., & Martens‐Uzunova, E. S.
- Venue
- Journal of Extracellular Vesicles
- Publisher
- Wiley
- Published
- 2021-05
- Volume
- 10
- Issue
- 7
- Pages
- e12093-e12093
- ISSN
- 2001-3078 (ISSN-L)
- OpenAlex
- W3164272096
- Cited by
- 404
- References
- 265
- FWCI
- 18.11
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles. https://app.cochat.ai/papers/10.1002/jev2.12093
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- Erdbrügger, U., Blijdorp, C. J., Bijnsdorp, I. V., Borràs, F. E., Burger, D., Bussolati, B., Byrd, J. B., Clayton, A., Dear, J. W., Falcón‐Pérez, J. M., Grange, C., Hill, A. F., Holthöfer, H., Hoorn, E. J., Jenster, G., Jimenez, C. R., Junker, K., Klein, J., Knepper, M. A., . . . Martens‐Uzunova, E. S. (2021). Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles. Journal of Extracellular Vesicles. https://doi.org/10.1002/jev2.12093
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
