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Cited by 404

The DOI matches its Crossref record; 265 of the 265 references it cites were found in a registry or an index.

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

Open access
Erdbrügger, Uta, Blijdorp, Charles J., Bijnsdorp, Irene V., Borràs, Francesc E., Burger, Dylan, Bussolati, Benedetta, Byrd, James Brian, Clayton, Aled, Dear, James W., Falcón‐Pérez, Juan M., Grange, Cristina, Hill, Andrew F., Holthöfer, Harry, Hoorn, Ewout J., Jenster, Guido, Jimenez, Connie R., Junker, Kerstin, Klein, John, Knepper, Mark A., Koritzinsky, Erik H., Luther, James M., Lenassi, Metka, Leivo, Janne, Mertens, Inge, Musante, Luca, Oeyen, Eline, Puhka, Maija, van Royen, Martin E., Sánchez, Catherine, Soekmadji, Carolina, Thongboonkerd, Visith, van Steijn, Volkert, Verhaegh, Gerald, Webber, Jason P., Witwer, Kenneth, Yuen, Peter S.T., Zheng, Lei, Llorente, Alicia, Martens‐Uzunova, Elena S.·2021·Journal of Extracellular Vesicles
DOI 10.1002/jev2.12093
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Abstract

Urine is commonly used for clinical diagnosis and biomedical research. The discovery of extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last decade urinary extracellular vesicles (uEVs) were shown to mirror molecular processes as well as physiological and pathological conditions in kidney, urothelial and prostate tissue. Therefore, several methods to isolate and characterize uEVs have been developed. However, methodological aspects of EV separation and analysis, including normalization of results, need further optimization and standardization to foster scientific advances in uEV research and a subsequent successful translation into clinical practice. This position paper is written by the Urine Task Force of the Rigor and Standardization Subcommittee of ISEV consisting of nephrologists, urologists, cardiologists and biologists with active experience in uEV research. Our aim is to present the state of the art and identify challenges and gaps in current uEV‐based analyses for clinical applications. Finally, recommendations for improved rigor, reproducibility and interoperability in uEV research are provided in order to facilitate advances in the field.

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Metadata

Authors
Erdbrügger, U., Blijdorp, C. J., Bijnsdorp, I. V., Borràs, F. E., Burger, D., Bussolati, B., Byrd, J. B., Clayton, A., Dear, J. W., Falcón‐Pérez, J. M., Grange, C., Hill, A. F., Holthöfer, H., Hoorn, E. J., Jenster, G., Jimenez, C. R., Junker, K., Klein, J., Knepper, M. A., Koritzinsky, E. H., Luther, J. M., Lenassi, M., Leivo, J., Mertens, I., Musante, L., Oeyen, E., Puhka, M., van Royen, M. E., Sánchez, C., Soekmadji, C., Thongboonkerd, V., van Steijn, V., Verhaegh, G., Webber, J. P., Witwer, K., Yuen, P. S. T., Zheng, L., Llorente, A., & Martens‐Uzunova, E. S.
Venue
Journal of Extracellular Vesicles
Publisher
Wiley
Published
2021-05
Volume
10
Issue
7
Pages
e12093-e12093
ISSN
2001-3078 (ISSN-L)
DOI
10.1002/jev2.12093
OpenAlex
W3164272096
Cited by
404
References
265
FWCI
18.11
Type
journal article
Language
en
Open access
gold

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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