Excess burden of constipation in Parkinson's disease: a pilot study
Abstract
An analysis was undertaken of clinic-based questionnaires that asked people with Parkinson's disease and a control group of older people without a known neurological condition about their experiences of constipation. People with Parkinson's disease report higher constipation on a validated objective measure, the Rome criterion (59% vs. 20.9%); a behavioral indicator, laxative-taking (38.4% vs. 14.2%); and subjective self-report of being always or often concerned by it (33.4% vs. 6.1%). Many people with Parkinson's disease experience constipation problems but they may not bring these to the attention of their healthcare providers. More research is required to understand the causes and management options.
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Constipation is associated with an increased risk of developing Parkinson's disease.
“In addition, constipation is assumed to be a harbinger and is associated with an increased risk of developing PD (Kaye et al., 2006;Sakakibara et al., 2003).”
From The Gut-Brain Axis in Parkinson’s Disease: Possibilities for Food-Based Therapies (2017) · cites this paper as Kaye et al., 2006
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- Authors
- Kaye, J., Gage, H., Kimber, A., Storey, L., & Trend, P.
- Affiliations
- University of Surrey (GB)
- University of Reading (GB)
- Royal Surrey County Hospital (GB)
- Corresponding author
- Gage, Heather
- Venue
- Movement Disorders
- Publisher
- Wiley
- Published
- 2006-05-12
- Volume
- 21
- Issue
- 8
- Pages
- 1270-1273
- ISSN
- 0885-3185 (ISSN-L)
- 1531-8257
- OpenAlex
- W2027350208
- Cited by
- 128
- References
- 16
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 6 · 2023: 5 · 2022: 5 · 2021: 15 · 2020: 4 · 2019: 6 · 2018: 6 · 2017: 12 · 2016: 6 · 2015: 8 · 2014: 6 · 2013: 4 · 2012: 7
- FWCI
- 4.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Movement Disorders (publishedVersion)
- PubMed (publishedVersion)
- Open Research (University of Surrey) (submittedVersion)
- CentAUR (University of Reading) (submittedVersion)
- ePrints Soton (University of Southampton) (submittedVersion)
- Surrey Research Insight Open Access (The University of Surrey) (submittedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
- Keywords
- Parkinson's disease, constipation, deadweight loss, Rome criteria, laxative use, self-reported symptoms, symptom underreporting, older adults, symptom burden
- MeSH terms
- Aged, Cathartics, Constipation, Humans, Parkinson Disease, Pilot Projects, Surveys and Questionnaires
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