Gastrointestinal dysfunction in Parkinson's disease

An Essay on the Shaking Palsy

Parkinson, J. (2002) · Journal of Neuropsychiatry · doi:10.1176/jnp.14.2.223 · Cited by 2,684 · see citing works

Gastric α-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology

Braak, H., de Vos, R. A. I., Bohl, J., & Del Tredici, K. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2005.11.012 · Cited by 1,354 · see citing works

Gastrointestinal dysfunction in Parkinson's disease

Pfeiffer, R. F. (2003) · The Lancet Neurology · doi:10.1016/s1474-4422(03)00307-7 · Cited by 925 · see citing works

Frequency of Bowel Movements and the Future Risk of Parkinson’s Disease

Abbott, R. D., Petrovitch, H., White, L. R., Masaki, K. H., Tanner, C. M., Curb, J. D., Grandinetti, A., Blanchette, P. L., Popper, J. S., & Ross, G. W. (2001) · Neurology · doi:10.1212/wnl.57.3.456 · Cited by 839 · see citing works

Consensus Recommendations for Gastric Emptying Scintigraphy: A Joint Report of the American Neurogastroenterology and Motility Society and the Society of Nuclear Medicine

Abell, T. L., Camilleri, M., Donohoe, K., Hasler, W. L., Lin, H. C., Maurer, A. H., McCallum, R. W., Nowak, T., Nusynowitz, M. L., Parkman, H. P., et al. (2008) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01636.x · Cited by 786 · see citing works

Where Does Parkinson Disease Pathology Begin in the Brain?

Del Tredici, K., Rüb, U., de Vos, R. A. I., Bohl, J. R. E., & Braak, H. (2002) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/61.5.413 · Cited by 773 · see citing works

Parkinson's disease: the presence of Lewy bodies in Auerbach's and Meissner's plexuses

Wakabayashi, K., Takahashi, H., Takeda, S., Ohama, E., & Ikuta, F. (1988) · Acta Neuropathologica · doi:10.1007/bf00687767 · Cited by 528 · see citing works

Progression of Dysarthria and Dysphagia in Postmortem-Confirmed Parkinsonian Disorders

Müller, J., Wenning, G. K., Verny, M., McKee, A. C., Chaudhuri, К. R., Jellinger, K. A., Poewe, W. H., & Litvan, I. (2001) · Archives of Neurology · doi:10.1001/archneur.58.2.259 · Cited by 414 · see citing works

Neuropathology of immunohistochemically identified brainstem neurons in Parkinson's disease

Halliday, G. M., Li, Y. W., Blumbergs, P. C., JOH, T. H., Cotton, R. G. H., Howe, P. R. C., Blessing, W. W., & Geffen, L. B. (1990) · Annals of Neurology · doi:10.1002/ana.410270405 · Cited by 409 · see citing works

Gastrointestinal symptoms in Parkinson's disease

Edwards, L. L., Pfeiffer, R. F., Quigley, E. M. M., Hofman, R., & Balluff, M. (1991) · Movement Disorders · doi:10.1002/mds.870060211 · Cited by 373 · see citing works

Dopaminergic defect of enteric nervous system in Parkinson's disease patients with chronic constipation.

Singaram, C., Gaumnitz, E., Torbey, C., Ashraf, W., Quigley, E. M., Sengupta, A., & Pfeiffer, R. F. (1995) · The Lancet · doi:10.1016/s0140-6736(95)92707-7 · Cited by 364 · see citing works

Questionnaire-based assessment of pelvic organ dysfunction in Parkinson's disease

Sakakibara, R., Shinotoh, H., Uchiyama, T., Sakuma, M., Kashiwado, M., Yoshiyama, M., & Hattori, T. (2001) · Autonomic Neuroscience · doi:10.1016/s1566-0702(01)00295-8 · Cited by 348 · see citing works

Parkinson's disease: an immunohistochemical study of Lewy body-containing neurons in the enteric nervous system

Wakabayashi, K., Takahashi, H., Ohama, E., & Ikuta, F. (1990) · Acta Neuropathologica · doi:10.1007/bf00294234 · Cited by 319 · see citing works

Management of faecal incontinence and constipation in adults with central neurological diseases

Coggrave, M., Norton, C. S., & Cody, J. D. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002115.pub5 · Cited by 318 · see citing works

Swallowing abnormalities and their response to treatment in Parkinson's disease

Bushmann, M., Dobmeyer, S. M., Leeker, L., & Perlmutter, J. S. (1989) · Neurology · doi:10.1212/wnl.39.10.1309 · Cited by 318 · see citing works

Esophageal Lewy bodies associated with ganglion cell loss in achalasia

Qualman, S. J., Haupt, H. M., Yang, P. H., & Hamilton, S. R. (1984) · Gastroenterology · doi:10.1016/0016-5085(84)90079-9 · Cited by 305 · see citing works

Esophageal Lewy bodies associated with ganglion cell loss in achalasia. Similarity to Parkinson's disease.

Qualman, S. J., Haupt, H. M., Yang, P. H., & Hamilton, S. R. (1984) · PubMed · Cited by 295 · see citing works

Swallowing and speech production in Parkinson's disease

Robbins, J. A., Logemann, J. A., & Kirshner, H. S. (1986) · Annals of Neurology · doi:10.1002/ana.410190310 · Cited by 277 · see citing works

Mechanisms of oral-pharyngeal dysphagia in patients with Parkinson's disease

Ali, G. N., Wallace, K., Schwartz, R., deCarle, D. J., Zagami, A. S., & Cook, I. (1996) · Gastroenterology · doi:10.1053/gast.1996.v110.pm8566584 · Cited by 274 · see citing works

Overview of morphological changes in Parkinson's disease.

Jellinger, K. A. (1987) · PubMed · Cited by 271 · see citing works

Compulsive eating and weight gain related to dopamine agonist use

Nirenberg, M. J., & Waters, C. (2005) · Movement Disorders · doi:10.1002/mds.20757 · Cited by 261 · see citing works

Gastric emptying time and gastric motility in patients with Parkinson's disease

Hardoff, R., Sula, M., Tamir, A., Soil, A., Front, A., Badarna, S., Honigman, S., & Giladi, N. (2001) · Movement Disorders · doi:10.1002/mds.1203 · Cited by 248 · see citing works

Swallowing disorders in Parkinson's disease

Potulska‐Chromik, A., Friedman, A., Królicki, L., & Spychała, A. (2003) · Parkinsonism & Related Disorders · doi:10.1016/s1353-8020(03)00045-2 · Cited by 236 · see citing works

Parkinson's disease and megacolon

Kupsky, W. J., Grimes, M. M., Sweeting, J. C., Bertsch, R., & Cote, L. J. (1987) · Neurology · doi:10.1212/wnl.37.7.1253 · Cited by 232 · see citing works

Dyssynergic Defecation and Biofeedback Therapy

Rao, S. S. C. (2008) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2008.06.011 · Cited by 231 · see citing works

Pharyngo-Esophageal Dysphagia in Parkinson's Disease

Leopold, N. A., & Kagel, M. C. (1997) · Dysphagia · doi:10.1007/pl00009512 · Cited by 213 · see citing works

Bowel movement frequency in late‐life and incidental Lewy bodies

Abbott, R. D., Ross, G. W., Petrovitch, H., Tanner, C. M., Davis, D. G., Masaki, K., Launer, L. J., Curb, J. D., & White, L. R. (2007) · Movement Disorders · doi:10.1002/mds.21560 · Cited by 203 · see citing works

Constipation in parkinson's disease: Objective assessment and response to psyllium

Ashraf, W., Pfeiffer, R. F., Park, F. L., Lof, J., & Quigley, E. (1997) · Movement Disorders · doi:10.1002/mds.870120617 · Cited by 200 · see citing works

Autonomic dysfunction in Parkinson's disease: a comprehensive symptom survey

Siddiqui, M. F., Rast, S. A., Lynn, M., Auchus, A. P., & Pfeiffer, R. F. (2002) · Parkinsonism & Related Disorders · doi:10.1016/s1353-8020(01)00052-9 · Cited by 195 · see citing works

Prepharyngeal dysphagia in Parkinson's disease

Leopold, N. A., & Kagel, M. C. (1996) · Dysphagia · doi:10.1007/bf00385794 · Cited by 192 · see citing works

Gastric emptying in Parkinson's disease

Djaldetti, R., Baron, J., Ziv, I., & Melamed, E. (1996) · Neurology · doi:10.1212/wnl.46.4.1051 · Cited by 189 · see citing works

Characterization of swallowing and defecation in Parkinson's disease.

Edwards, L. L., Quigley, E. M. M., Harned, R. K., Hofman, R., & Pfeiffer, R. F. (1994) · PubMed · Cited by 187 · see citing works

Oral Erythromycin and Symptomatic Relief of Gastroparesis: A Systematic Review

Maganti, K., Onyemere, K., & Jones, M. P. (2003) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07167.x · Cited by 182 · see citing works

Salivary production in Parkinson's disease

Proulx, M., Courval, F. P. D., Wiseman, M. A., & Panisset, M. (2004) · Movement Disorders · doi:10.1002/mds.20189 · Cited by 182 · see citing works

Swallowing difficulty in Parkinson's disease

Fuh, J., Lee, R., Wang, S., Lin, C.-H., Wang, P.-N., Chiang, J., & Liu, H.-C. (1997) · Clinical Neurology and Neurosurgery · doi:10.1016/s0303-8467(97)80006-6 · Cited by 179 · see citing works

Videofluorographic Study of Swallowing in Parkinson's Disease

Nagaya, M., Kachi, T., Yamada, T., & Igata, A. (1998) · Dysphagia · doi:10.1007/pl00009562 · Cited by 178 · see citing works

Gastrointestinal Motility Problems in Patients with Parkinsonʼs Disease

Jost, W. H. (1997) · Drugs & Aging · doi:10.2165/00002512-199710040-00002 · Cited by 178 · see citing works

Macrogol for the treatment of constipation in Parkinson’s disease. A randomized placebo-controlled study

Zangaglia, R., Martignoni, E., Glorioso, M., Ossola, M., Riboldazzi, G., Calandrella, D., Brunetti, G., & Pacchetti, C. (2007) · Movement Disorders · doi:10.1002/mds.21243 · Cited by 177 · see citing works

Gastroparesis: Current diagnostic challenges and management considerations

Waseem, S., Moshiree, B., & Draganov, P. V. (2008) · World Journal of Gastroenterology · doi:10.3748/wjg.15.25 · Cited by 177 · see citing works

Weight Change and Body Composition in Patients With Parkinson's Disease

BEYER, P. L., PALARINO, M. Y., Michalek, D. K., Busenbark, K. L., & Koller, W. C. (1995) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(95)00269-3 · Cited by 173 · see citing works

Erratic gastric emptying of levodopa may cause “random” fluctuations of parkinsonian mobility

Kurlan, R., Rothfield, K. P., Woodward, W. R., Nutt, J. G., Miller, C., Lichter, D. G., & Shoulson, I. (1988) · Neurology · doi:10.1212/wnl.38.3.419 · Cited by 168 · see citing works

Measurement of Gastrointestinal Transit

Lin, H. C., Prather, C., Fisher, R., Meyer, J. H., Summers, R., Pimentel, M., McCallum, R., Akkermans, L., Loening-Baucke, V., & Ams Task Force Committee on Gastrointestinal Transit (2005) · Digestive Diseases and Sciences · doi:10.1007/s10620-005-2694-6 · Cited by 168 · see citing works

Asymptomatic Swallowing Disorders in Elderly Patients with Parkinson's Disease: A Description of Findings on Clinical Examination and Videofluoroscopy in Sixteen Patients

Bird, M., Woodward, M. C., Gibson, E. M., et al. (1994) · Age and Ageing · doi:10.1093/ageing/23.3.251 · Cited by 165 · see citing works

Colonic transit time and rectoanal videomanometry in Parkinson's disease

Sakakibara, R., Odaka, T., Uchiyama, T., Asahina, M., Yamaguchi, K., Yamaguchi, T., Yamanishi, T., & Hattori, T. (2003) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.74.2.268 · Cited by 164 · see citing works

Effect of chronic oral domperidone therapy on gastrointestinal symptoms and gastric emptying in patients with parkinson's disease

Soykan, İ., Sarosiek, I., Shifflett, J., Wooten, G. F., & McCallum, R. W. (1997) · Movement Disorders · doi:10.1002/mds.870120618 · Cited by 163 · see citing works

Sublingual Atropine for sialorrhea secondary to parkinsonism: A pilot study

Hyson, H. C., Johnson, A. M., & Jog, M. (2002) · Movement Disorders · doi:10.1002/mds.10276 · Cited by 163 · see citing works

Anal Sphincter Dysfunction in Parkinson's Disease

Mathers, S. E., Kempster, P. A., Law, P. J., Frankel, J. P., Bartram, C. I., Lees, A. J., Stern, G. M., & Swash, M. (1989) · Archives of Neurology · doi:10.1001/archneur.1989.00520460037010 · Cited by 158 · see citing works

Constipation and paradoxical puborectalis contraction in anismus and Parkinson's disease: a dystonic phenomenon?

Mathers, S., Kempster, P. A., Swash, M., & Lees, A. J. (1988) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.51.12.1503 · Cited by 158 · see citing works

Sialorrhea in Parkinson's disease: A review

Chou, K. L., Evatt, M. L., Hinson, V. K., & Kompoliti, K. (2007) · Movement Disorders · doi:10.1002/mds.21646 · Cited by 149 · see citing works

A study of salivary secretion in Parkinson's disease.

Bagheri, H., Damase‐Michel, C., Lapeyre‐Mestre, M., Cismondo, S., O'Connell, D., Sénard, J., Rascol, O., & Montastruc, J. (1999) · PubMed · Cited by 148 · see citing works

Predictors of gastric emptying in Parkinson's disease

Goetze, O., Nikodem, A., Wiezcorek, J., Banasch, M., Przuntek, H., Mueller, T. J., Schmidt, W. E., & Woitalla, D. (2006) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2006.00780.x · Cited by 146 · see citing works

Diet, body size and micronutrient status in Parkinson's disease.

Abbott, R. A., Cox, M., Markus, H. S., & Tomkins, A. M. (1992) · PubMed · Cited by 139 · see citing works

ALIMENTARY DISORDER IN PARKINSONISM

Eadie, M. J., & Tyrer, J. H. (1965) · Australasian Annals of Medicine · doi:10.1111/imj.1965.14.1.13 · Cited by 138 · see citing works

Impact of Gastric Emptying on Levodopa Pharmacokinetics in Parkinson Disease Patients

M�ller, T., Erdmann, C., Bremen, D., Schmidt, W. E., Muhlack, S., Woitalla, D., & Goetze, O. (2006) · Clinical Neuropharmacology · doi:10.1097/00002826-200603000-00001 · Cited by 131 · see citing works

Erythromycin: a motilin agonist and gastrointestinal prokinetic agent.

Weber, F. H., Richards, R. D., & McCallum, R. W. (1993) · PubMed · Cited by 130 · see citing works

Excess burden of constipation in Parkinson's disease: a pilot study

Kaye, J., Gage, H., Kimber, A., Storey, L., & Trend, P. (2006) · Movement Disorders · doi:10.1002/mds.20942 · Cited by 128 · see citing works

Quantitative study of salivary secretion in Parkinson's disease

Tumilasci, O. R., Cersosimo, M. G., Belforte, J. E., Micheli, F. E., Benarroch, E. E., & Pazo, J. H. (2006) · Movement Disorders · doi:10.1002/mds.20784 · Cited by 128 · see citing works

Factors Associated with Symptom Response to Pyloric Injection of Botulinum Toxin in a Large Series of Gastroparesis Patients

Coleski, R., Anderson, M., & Hasler, W. (2009) · Digestive Diseases and Sciences · doi:10.1007/s10620-008-0660-9 · Cited by 119 · see citing works

Impaired gastric emptying of a solid test meal in patients with Parkinson's disease using 13C-sodium octanoate breath test

Goetze, O., Wieczorek, J., Mueller, T. J., Przuntek, H., Schmidt, W. E., & Woitalla, D. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.11.007 · Cited by 116 · see citing works

Irregular gastrointestinal drug absorption in Parkinson's disease

Nyholm, D., & Lennernäs, H. (2008) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1517/17425255.4.2.193 · Cited by 115 · see citing works

Defecatory function in Parkinson's disease: Response to apomorphine

Edwards, L. L., Quigley, E. M. M., Harned, R. K., Hofman, R., & Pfeiffer, R. F. (1993) · Annals of Neurology · doi:10.1002/ana.410330512 · Cited by 114 · see citing works

Botulinum toxin: Clinical use

Truong, D. D., & Jost, W. H. (2006) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2006.06.002 · Cited by 112 · see citing works

Radiological assessment of dysphagia in Parkinson's disease

Stroudley, J., & Walsh, M. (1991) · British Journal of Radiology · doi:10.1259/0007-1285-64-766-890 · Cited by 109 · see citing works

Botulinum Toxin for Cricopharyngeal Dysfunction in Parkinson's Disease

Restivo, D. A., Palmeri, A., & Marchese‐Ragona, R. (2002) · New England Journal of Medicine · doi:10.1056/nejm200204113461517 · Cited by 107 · see citing works

Oral Health Conditions in Patients with Parkinson's Disease

Nakayama, Y., Washio, M., & Mori, M. (2004) · Journal of Epidemiology · doi:10.2188/jea.14.143 · Cited by 105 · see citing works

Macrogol 3350/electrolyte improves constipation in Parkinson's disease and multiple system atrophy

Eichhorn, T. E., & Oertel, W. H. (2001) · Movement Disorders · doi:10.1002/mds.1211 · Cited by 103 · see citing works

Manometric investigation of anorectal function in early and late stage Parkinson's disease

Bassotti, G. (2000) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.68.6.768 · Cited by 103 · see citing works

Bilateral subthalamic nucleus stimulation in a parkinsonian patient with preoperative deficits in speech and cognition: Persistent improvement in mobility but increased dependency: A case study

Hariz, M. I., Johansson, F., Shamsgovara, P., Johansson, E., Hariz, G., & Fagerlund, M. (2000) · Movement Disorders · doi:10.1002/1531-8257(200001)15:1 · Cited by 102 · see citing works

Is drooling secondary to a swallowing disorder in patients with Parkinson's disease?

Nóbrega, A. C., Rodrigues, B., Torres, A. C. M., Scarpel, R. D., Neves, C. A., & Melo, A. D. S. (2007) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2007.08.003 · Cited by 100 · see citing works

Effects of central dopaminergic stimulation by apomorphine on swallowing disorders in Parkinson's disease

Tison, F., Wiart, L., Guatterie, M., Fouillet, N., Lozano, V., Henry, P., & Barat, M. (1996) · Movement Disorders · doi:10.1002/mds.870110622 · Cited by 95 · see citing works

Burning mouth in Parkinson's Disease sufferers

Clifford, T. J., Warsi, M., Burnett, C., et al. (1998) · Gerodontology · doi:10.1111/j.1741-2358.1998.00073.x · Cited by 94 · see citing works

Constipation in Parkinson's disease

Jost, W. H., & Schimrigk, К. (1991) · Journal of Molecular Medicine · doi:10.1007/bf01798536 · Cited by 94 · see citing works

Outlet type constipation in Parkinson's disease: results of botulinum toxin treatment

Cadeddu, F., Bentivoglio, A. R., Brandara, F., Marniga, G., Brisinda, G., & Maria, G. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02669.x · Cited by 91 · see citing works

Referral criteria for speech and language therapy assessment of dysphagia caused by idiopathic Parkinson's disease

Clarke, C. E., Gullaksen, E., Macdonald, S., & Lowe, F. (2009) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1998.tb00605.x · Cited by 90 · see citing works

Mirtazapine for Severe Gastroparesis Unresponsive to Conventional Prokinetic Treatment

Kim, S.-W., Shin, I., Kim, J.-M., Kang, H., Mun, J.-U., Yang, S., & Yoon, J. (2006) · Psychosomatics · doi:10.1176/appi.psy.47.5.440 · Cited by 90 · see citing works

Erythromycin in the Short- and Long-term Control of Dyspepsia Symptoms in Patients with Gastroparesis

Dhir, R., & Richter, J. (2004) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-200403000-00008 · Cited by 88 · see citing works

Impact of drooling in Parkinson’s disease

Kalf, J. G., Smit, A. M., Bloem, B. R., Zwarts, M. J., & Munneke, M. (2007) · Journal of Neurology · doi:10.1007/s00415-007-0508-9 · Cited by 87 · see citing works

Biomechanics of failed deglutitive upper esophageal sphincter relaxation in neurogenic dysphagia

Williams, R. B. H., Wallace, K. L., Ali, G. N., & Cook, I. J. (2002) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00189.2001 · Cited by 83 · see citing works

Management of faecal incontinence and constipation in adults with central neurological diseases

Coggrave, M., Wiesel, P. H., & Norton, C. C. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002115.pub3 · Cited by 82 · see citing works

Cricopharyngeal dysfunction in Parkinson's disease: Role in dysphagia and response to myotomy

Born, L. J., Harned, R. H., Rikkers, L. F., Pfeiffer, R. F., & Quigley, E. M. M. (1996) · Movement Disorders · doi:10.1002/mds.870110110 · Cited by 81 · see citing works

Comparative study between biofeedback retraining and botulinum neurotoxin in the treatment of anismus patients

Farid, M. I., Monem, H. A. E., Omar, W., Nakeeb, A. E., Fikry, A. A., Youssef, T., Yousef, M., Ghazy, H., Fouda, E., Metwally, T. E., et al. (2008) · International Journal of Colorectal Disease · doi:10.1007/s00384-008-0567-0 · Cited by 81 · see citing works

Parkinson's disease and weight loss: A study with anthropometric and nutritional assessment

Durrieu, G., Llau, M. E., Rascol, O., Sénard, J., Rascol, A., & Montastruc, J. (1992) · Clinical Autonomic Research · doi:10.1007/bf01818955 · Cited by 78 · see citing works

Ipratropium bromide spray as treatment for sialorrhea in Parkinson's disease

Thomsen, T. R., Galpern, W. R., Asante, A., Arenovich, T., & Fox, S. H. (2007) · Movement Disorders · doi:10.1002/mds.21730 · Cited by 78 · see citing works

Severe constipation in parkinson's disease relieved by botulinum toxin

Albanese, A., Maria, G., Bentivoglio, A. R., Brisinda, G., Cassetta, E., & Tonali, P. A. (1997) · Movement Disorders · doi:10.1002/mds.870120524 · Cited by 76 · see citing works

Gastrointestinal Dysfunction in Parkinson's Disease

Quigley, E. M. M. (1996) · Seminars in Neurology · doi:10.1055/s-2008-1040981 · Cited by 74 · see citing works

Anorectal function in fluctuating (on‐off) Parkinson's disease: Evaluation by combined anorectal manometry and electromyography

Ashraf, W., Wszołek, Z. K., Pfeiffer, R. F., Normand, M. M., Maurer, K. B., Srb, F., Edwards, L. L., & Quigley, E. M. M. (1995) · Movement Disorders · doi:10.1002/mds.870100519 · Cited by 74 · see citing works

Treatment of Outlet Obstruction Constipation in Parkinson'S Disease With Botulinum Neurotoxin A

Albanese, A., Brisinda, G., Bentivoglio, A. R., & Maria, G. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07514.x · Cited by 73 · see citing works

Manometric abnormalities of the oesophagus in patients with Parkinson’s disease

Castell, J. A., Johnston, B. T., Colcher, A., et al. (2001) · Neurogastroenterology & Motility · doi:10.1046/j.1365-2982.2001.00275.x · Cited by 72 · see citing works

Increased periodontal pathology in Parkinson's disease

Schwarz, J., Heimhilger, E., & Storch, A. (2006) · Journal of Neurology · doi:10.1007/s00415-006-0068-4 · Cited by 71 · see citing works

Gastric emptying rate and the systemic availability of levodopa in the elderly parkinsonian patient

Evans, M. A., Broe, G. A., TRIGGS, E. J., Cheung, M., Creasey, H. M., & Paull, P. (1981) · Neurology · doi:10.1212/wnl.31.10.1288 · Cited by 71 · see citing works

Increased gastric motility during 5-HT4 agonist therapy reduces response fluctuations in Parkinson's disease

Asai, H., Udaka, F., Hirano, M., Minami, T., Oda, M., Kubori, T., Nishinaka, K., Kameyama, M., & Ueno, S. (2005) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2005.06.007 · Cited by 71 · see citing works

Gastrointestinal Dysfunction in Parkinson???s Disease

Byrne, K. G., Pfeiffer, R. F., & Quigley, E. M. M. (1994) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-199407000-00004 · Cited by 70 · see citing works

Influence of Parkinson's disease on oral health

Persson, M., Sterberg, T. Ö., Granérus, A., et al. (1992) · Acta Odontologica Scandinavica · doi:10.3109/00016359209012744 · Cited by 69 · see citing works

Weight and body mass index in Parkinson's disease patients after deep brain stimulation surgery

Tuite, P. J., Maxwell, R. E., Ikramuddin, S., et al. (2005) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2005.01.006 · Cited by 68 · see citing works

Gastric Electrical Stimulation for Gastroparesis

Brody, F. J., Vaziri, K., Saddler, A., Ali, A. M., Drenon, E., Hanna, B., Akin, E. A., Gonzalez, F., & Soffer, E. (2008) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2008.04.032 · Cited by 68 · see citing works

Domperidone and levodopa in Parkinson's disease.

Shindler, J. S., Finnerty, G. T., Towlson, K. E., et al. (1984) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1984.tb02571.x · Cited by 62 · see citing works

Megacolon and Volvulus in Parkinson's Disease

Caplan, L. H., Jacobson, H. G., Rubinstein, B. M., & Rotman, M. Z. (1965) · Radiology · doi:10.1148/85.1.73 · Cited by 61 · see citing works

Anorectal manometry in the assessment of anorectal function in Parkinson's disease: A comparison with chronic idiopathic constipation

Ashraf, W., Pfeiffer, R. F., & Quigley, E. M. M. (1994) · Movement Disorders · doi:10.1002/mds.870090612 · Cited by 61 · see citing works

Gastric emptying after semi–solid food in multiple system atrophy and Parkinson disease

Thomaides, T., Karapanayiotides, T., Zoukos, Y., Haeropoulos, C., Kerezoudi, E., Demacopoulos, N., Floodas, G., Papageorgiou, E., Armakola, F., Thomopoulos, Y., et al. (2005) · Journal of Neurology · doi:10.1007/s00415-005-0815-y · Cited by 60 · see citing works

Effect of cisapride on response fluctuations in Parkinson's disease

Djaldetti, R., Koren‐Michowitz, M., Ziv, I., Achiron, A., & Melamed, E. (1995) · Movement Disorders · doi:10.1002/mds.870100113 · Cited by 58 · see citing works

Salivary Symptoms in Parkinson Disease

Bateson, M. C., Gibberd, F. B., & Wilson, R. S. (1973) · Archives of Neurology · doi:10.1001/archneur.1973.00490280086013 · Cited by 57 · see citing works

Esophageal Manometric Abnormalities in Parkinson's Disease

Bassotti, G., Germani, U., Pagliaricci, S., et al. (1998) · Dysphagia · doi:10.1007/pl00009546 · Cited by 51 · see citing works

Anorectal and pelvic floor function. Relevance of continence, incontinence, and constipation.

Sagar, P., & Pemberton, J. (1996) · Gastroenterology Clinics of North America · doi:10.1016/s0889-8553(05)70370-8 · Cited by 51 · see citing works

Sigmoid Volvulus in Association With Parkinsonism Report of Four Cases

Rosenthal, M. J., & Marshall, C. E. (1987) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1987.tb04346.x · Cited by 50 · see citing works

Defecatory disorders in de novo Parkinsonians--colonic transit and electromyogram of the external anal sphincter.

Jost, W. H., & Schrank, B. (1998) · PubMed · Cited by 50 · see citing works

Long‐Term Follow‐Up of Tympanic Neurectomy for Sialorrhea

Mullins, W. M., Gross, C. W., & Moore, J. M. (1979) · The Laryngoscope · doi:10.1002/lary.1979.89.8.1219 · Cited by 49 · see citing works

Clinical and pharmacokinetic comparison of oral and duodenal delivery of levodopa/carbidopa in patients with Parkinson's disease with a fluctuating response to levodopa

Deleu, D., Ebinger, G., & Michotte, Y. M. (1991) · European Journal of Clinical Pharmacology · doi:10.1007/bf00626368 · Cited by 45 · see citing works

Oral Health of Patients with Parkinson's Disease: Factors Related to Their Better Dental Status

Fukayo, S., Nonaka, K., Shimizu, T., et al. (2003) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.201.171 · Cited by 42 · see citing works

Sialorrhoea and Drooling in Patients with Parkinson’s Disease

Merello, M. (2008) · Drugs & Aging · doi:10.2165/0002512-200825120-00003 · Cited by 39 · see citing works

Impaired absorption of oral levodopa: a major cause for response fluctuations in Parkinson's disease.

Djaldetti, R., Ziv, I., & Melamed, E. (1996) · PubMed · Cited by 29 · see citing works

The effect of cisapride on delayed colonic transit time in patients with idiopathic Parkinson's disease.

Jost, W. H., & Schimrigk, К. (1994) · PubMed · Cited by 27 · see citing works

Treatment of Gastroparesis: An Update

Gumaste, V. V., & Baum, J. (2008) · Digestion · doi:10.1159/000185690 · Cited by 26 · see citing works

Current management of motor fluctuations in patients with advanced Parkinson’s disease treated chronically with levodopa

Melamed, E., Zoldan, J., Galili-Mosberg, R., Ziv, I., & Djaldetti, R. (1999) · Journal of neural transmission. Supplementum · doi:10.1007/978-3-7091-6360-3_11 · Cited by 24 · see citing works

The Role of Biofeedback Therapy in Functional Proctologic Disorders

Kairaluoma, M. V., Raivio, P., Kupila, J., Aarnio, M., & Kellokumpu, I. (2004) · Scandinavian Journal of Surgery · doi:10.1177/145749690409300303 · Cited by 23 · see citing works

Dysphagia, a reversible cause not to be forgotten

Thomas, M. C., & Haigh, R. A. (1995) · Postgraduate Medical Journal · doi:10.1136/pgmj.71.832.94 · Cited by 16 · see citing works

Pathogenesis of slow transit and pelvic floor dysfunction: from bench to bedside.

Crowell, M. D. (2004) · PubMed · Cited by 13 · see citing works

Bruxism as presenting feature of Parkinson's disease.

Srivastava, T., Ahuja, M., Srivastava, M., et al. (2002) · PubMed · Cited by 12 · see citing works

Botulinum toxin type A for treatment of refractory gastroparesis

DeSantis, E. R. H., & Huang, S. (2007) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp060394 · Cited by 9 · see citing works

[Habitual mandibular dislocation in two patients with Parkinson's disease].

Sayama, S., Fujimoto, K., Shizuma, N., et al. (1999) · PubMed · Cited by 8 · see citing works

An Appliance for Management of TMJ Pain as a Complication of Parkinson's Disease

Minagi, S., Matsunaga, T., Shibata, T., et al. (1998) · CRANIO® · doi:10.1080/08869634.1998.11746039 · Cited by 8 · see citing works

Neuro-Gastroenterology

Floch, M. H. (2004) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-200408000-00022 · Cited by 6 · see citing works

Simultaneous electromyography and manometry of the anal sphincters in parkinsonian patients: technical considerations.

Normand, M. M., Ashraf, W., Quigley, E. M., et al. (1996) · PubMed · Cited by 5 · see citing works

Gut microbiota are related to Parkinson's disease and clinical phenotype

Scheperjans, F., Aho, V., Pereira, P. A. B., Koskinen, K., Paulin, L., Pekkonen, E., Haapaniemi, E., Kaakkola, S., Eerola‐Rautio, J., Pohja, M., et al. (2015) · Movement Disorders · doi:10.1002/mds.26069 · Cited by 1,968 · see citing works

Gastrointestinal Dysfunction in Parkinson’s Disease

Fasano, A., Visanji, N. P., Liu, L. W. C., Lang, A. E., & Pfeiffer, R. F. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)00007-1 · Cited by 1,016 · see citing works

Brain-Gut-Microbiota Axis in Parkinson’s Disease

Mulak, A. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i37.10609 · Cited by 583 · see citing works

Structural changes of gut microbiota in Parkinson's disease and its correlation with clinical features

Li, W., Wu, X., Hu, X., Wang, T., Liang, S., Duan, Y., Jin, F., & Qin, B. (2017) · Science China Life Sciences · doi:10.1007/s11427-016-9001-4 · Cited by 406 · see citing works

Exploring Braak’s hypothesis of Parkinson’s disease

Rietdijk, C. D., Perez-Pardo, P., Garssen, J., van Wezel, R. J. A., & Kraneveld, A. D. (2017) · Frontiers in Neurology · doi:10.3389/fneur.2017.00037 · Cited by 395 · see citing works

Gastrointestinal manifestations in Parkinson's disease: Prevalence and occurrence before motor symptoms

Cersosimo, M. G., Raina, G. B., Pecci, C., Pellene, A., Calandra, C. R., Gutiérrez, C., Micheli, F. E., & Benarroch, E. E. (2013) · Journal of Neurology · doi:10.1007/s00415-012-6801-2 · Cited by 314 · see citing works

Small intestinal bacterial overgrowth in Parkinson's disease

Tan, A. H., Mahadeva, S., Thalha, A. M., Gibson, P. R., Kiew, C. K., Yeat, C. M., Ng, S. W., Ang, S. P., Chow, S. K., Tan, C. T., et al. (2014) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2014.02.019 · Cited by 274 · see citing works

The Microbiome as a Modifier of Neurodegenerative Disease Risk

Fang, P., Kazmi, S. A., Jameson, K. G., & Hsiao, E. Y. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.06.008 · Cited by 226 · see citing works

Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology

Manfredsson, F. P., Luk, K. C., Benskey, M. J., Gezer, A., Garcia, J., Kuhn, N. C., Sandoval, I. M., Patterson, J. R., O'Mara, A., Yonkers, R., et al. (2018) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.01.008 · Cited by 199 · see citing works

The Gut-Brain Axis in Parkinson’s Disease: Possibilities for Food-Based Therapies

Perez-Pardo, P., Kliest, T., Dodiya, H. B., Broersen, L. M., Garssen, J., Keshavarzian, A., & Kraneveld, A. D. (2017) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2017.05.042 · Cited by 203 · see citing works

Systematic Analysis of Gut Microbiome Reveals the Role of Bacterial Folate and Homocysteine Metabolism in Parkinson’s Disease

Rosario, D., Bidkhori, G., Lee, S., Bedarf, J., Hildebrand, F., Le Chatelier, E., Uhlen, M., Ehrlich, S. D., Proctor, G., Wüllner, U., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108807 · Cited by 167 · see citing works

Lactobacillus Plantarum PS128 Alleviates Neurodegenerative Progression in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Mouse Models of Parkinson’s Disease

Liao, J.-F., Cheng, Y.-F., You, S.-T., Kuo, W.-C., Huang, C.-W., Chiou, J.-J., Hsu, C.-C., Hsieh-Li, H.-M., Wang, S., & Tsai, Y.-C. (2020) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2020.07.036 · Cited by 159 · see citing works

Diet in Parkinson’s Disease: Critical Role for the Microbiome

Jackson, A., Forsyth, C. B., Shaikh, M., Voigt, R. M., Engen, P. A., Ramirez, V., & Keshavarzian, A. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.01245 · Cited by 145 · see citing works

Effect of Parkinson’s Disease and Related Medications on the Composition of the Fecal Bacterial Microbiota

Weis, S., Schwiertz, A., Unger, M. M., Becker, A., Faßbender, K., Ratering, S., Kohl, M., Schnell, S., Schäfer, K.-H., & Egert, M. (2019) · npj Parkinson s Disease · doi:10.1038/s41531-019-0100-x · Cited by 145 · see citing works

Gut-brain and brain-gut axis in Parkinson’s disease models: effects of a uridine and fish oil diet

Perez-Pardo, P., Dodiya, H. B., Broersen, L. M., Douna, H., van Wijk, N., Lopes da Silva, S., Garssen, J., Keshavarzian, A., & Kraneveld, A. D. (2018) · Nutritional Neuroscience · doi:10.1080/1028415x.2017.1294555 · Cited by 111 · see citing works

Fecal microbiota transplant as a potential treatment for Parkinson's disease – A case series

Segal, A., Zlotnik, Y., Moyal-Atias, K., Abuhasira, R., & Ifergane, G. (2021) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2021.106791 · Cited by 124 · see citing works

Gut bacterial composition in a mouse model of Parkinson’s disease

Perez-Pardo, P., Dodiya, H. B., Engen, P. A., Naqib, A., Forsyth, C. B., Green, S. J., Garssen, J., Keshavarzian, A., & Kraneveld, A. D. (2018) · Beneficial Microbes · doi:10.3920/bm2017.0202 · Cited by 102 · see citing works

Gastrointestinal Dysfunction in Parkinson’s Disease

Pfeiffer, R. F. (2018) · Current Treatment Options in Neurology · doi:10.1007/s11940-018-0539-9 · Cited by 94 · see citing works

Promising effects of neurorestorative diets on motor, cognitive, and gastrointestinal dysfunction after symptom development in a mouse model of Parkinson's disease

Perez-Pardo, P., de Jong, E. M., Broersen, L. M., van Wijk, N., Attali, A., Garssen, J., & Kraneveld, A. D. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00057 · Cited by 74 · see citing works

Gastrointestinal autonomic dysfunction in patients with Parkinson’s disease

Kim, J.-S., & Sung, H.-Y. (2015) · Journal of Movement Disorders · doi:10.14802/jmd.15008 · Cited by 76 · see citing works

Assessments of plasma ghrelin levels in the early stages of Parkinson's disease

Song, N., Wang, W., Jia, F., Du, X., Xie, A., He, Q., Shen, X., Zhang, J., Rogers, J. T., Xie, J., et al. (2017) · Movement Disorders · doi:10.1002/mds.27095 · Cited by 67 · see citing works

Gastrointestinal features of Parkinson’s disease

Cloud, L. J., & Greene, J. G. (2011) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-011-0204-0 · Cited by 67 · see citing works

Effect of acupuncture on the motor and nonmotor symptoms in Parkinson’s disease-a review of clinical studies

Zeng, B., & Zhao, K. (2016) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12507 · Cited by 64 · see citing works

Dopamine transporter availability reflects gastrointestinal dysautonomia in early Parkinson disease

Hinkle, J. T., Perepezko, K., Mills, K. A., Mari, Z., Butala, A., Dawson, T. M., Pantelyat, A., Rosenthal, L. S., & Pontone, G. M. (2018) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2018.08.010 · Cited by 49 · see citing works

Analysis of Diagnosis and Treatment of Gastroparesis After Gastrointestinal Operation

Jian-we, Z. (2014) · Guide of China Medicine

Quiet but powerful: the role of the enteric nervous system in the pathophysiology of gastrointestinal disease (214.1)

Gershon, M. D. (2014) · The FASEB Journal · doi:10.1096/fasebj.28.1_supplement.214.1 · Cited by 2 · see citing works

Clinical nutrition in gastrointestinal diseases

Hamvas, J. (2014) · Orvosi Hetilap · doi:10.1556/oh.2014.29983

CLINICAL OBSERVATION OF GLUTAMINE TREATMENT IN 60 PATIENTS WITH SEVERE GASTROINTESTINAL DYSFUNCTION

Yong-fu, Y. (2011) · Xiandai yufang yixue

Gastrointestinal failure in the ICU

Blaser, A. R., Jakob, S. M., & Starkopf, J. (2016) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000000286 · Cited by 64 · see citing works