pH ‐sensitive polymers: Classification and some fine potential applications
Open accessAbstract
Stimuli‐responsive materials in general and pH‐responsive polymers in particular have gained increasing interest during the last two decades. Their unique properties, which arise from their ability to exhibit sharp and reversible changes in response to environmental pH conditions, have made them suitable for various applications such as drug delivery and specific body‐site targeting, sensing and actuation, membrane functionalization, separation techniques, as well as in agriculture and food industry and even chemical industries. In the present review, the focus is on the general characteristics of pH‐responsive polymers in terms of their origin, chemical composition, and preparation. Moreover, some of the important and recent applications are reported and discussed.
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Nanoparticles, nanoaggregates, nanogels, nanocapsules, core-shell particles, micelles, liposomes, polymersomes, hydrogels, layer-by-layer films, and bioconjugates have been developed as pH-sensitive polymer-based drug delivery devices.
“Nanoparticles, nanoaggregates, nanogels, nanocapsules, core-shell particles, micelles, liposomes, polymersomes, hydrogels, layer-by-layer films, and bioconjugates have been developed as pH-sensitive polymer-based drug delivery devices (Hendi et al., 2020; Li et al., 2021; Ofridam et al., 2021).”
From pH stimuli-responsive hydrogels from non-cellulosic biopolymers for drug delivery. (2023) · cites this paper as Ofridam et al., 2021
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1 retracted
Shah, S. A., Sohail, M. F., Minhas, M. U., Nisar-ur-Rehman, Khan, S., Hussain, Z., Mudassir, Mahmood, A., Kousar, M., & Mahmood, A. (2018) · Drug Delivery and Translational Research · doi:10.1007/s13346-018-0486-8 · Cited by 52 · see citing works
RetractedChitin and chitosan: Properties and applications
Rinaudo, M. (2006) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2006.06.001 · Cited by 8,378 · see citing works
Emerging applications of stimuli-responsive polymer materials
Stuart, M. A. C., Huck, W. T. S., Genzer, J., Müller, M., Ober, C. K., Stamm, M., Sukhorukov, G. B., Szleifer, I. G., Tsukruk, V. V., Urban, M. W., et al. (2010) · Nature Materials · doi:10.1038/nmat2614 · Cited by 5,720 · see citing works
Environment-sensitive hydrogels for drug delivery
Qiu, Y., & Park, K. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00203-4 · Cited by 3,917 · see citing works
Hydrogels for biomedical applications
Hoffman, A. S. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.010 · Cited by 3,396 · see citing works
Kamaly, N., Yameen, B., Wu, J., & Farokhzad, O. C. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00346 · Cited by 3,070 · see citing works
Thermo- and pH-responsive polymers in drug delivery☆
SCHMALJOHANN, D. (2006) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2006.09.020 · Cited by 3,023 · see citing works
Stimuli-reponsive polymers and their bioconjugates
Gil, E. S., & Hudson, S. M. (2004) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2004.08.003 · Cited by 2,385 · see citing works
Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan—a review
George, M., & Abraham, T. E. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.04.017 · Cited by 2,012 · see citing works
Polymer conjugates as anticancer nanomedicines
Duncan, R. (2006) · Nature reviews. Cancer · doi:10.1038/nrc1958 · Cited by 1,956 · see citing works
Hydrogels: From controlled release to pH-responsive drug delivery
Gupta, P., Vermani, K., & Garg, S. (2002) · Drug Discovery Today · doi:10.1016/s1359-6446(02)02255-9 · Cited by 1,825 · see citing works
Stimuli-responsive polymers and their applications
Wei, M., Gao, Y., Li, X., & Serpe, M. J. (2016) · Polymer Chemistry · doi:10.1039/c6py01585a · Cited by 1,305 · see citing works
Poly(ethylenimine) and its role in gene delivery
Godbey, W. T., Wu, K. K., & Mikos, A. G. (1999) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00090-5 · Cited by 1,200 · see citing works
Stimulus-responsive hydrogels: theory, modern advances, and applications
Koetting, M. C., Peters, J. T., Steichen, S. D., & Peppas, N. A. (2015) · Materials Science and Engineering: R: Reports · doi:10.1016/j.mser.2015.04.001 · Cited by 1,191 · cited 2× · see citing works
“66 They are defined as hydrophilic polymer networks and may absorb from 10% to 20% up to thousands of times their dry weight in water.”
BackgroundKocak, G., Tuncer, C., & Bütün, V. (2017) · Polymer Chemistry · doi:10.1039/c6py01872f · Cited by 1,189 · see citing works
Fujishige, S., Kubota, K., & Ando, I. (1989) · The Journal of Physical Chemistry · doi:10.1021/j100345a085 · Cited by 1,143 · see citing works
pH-Sensitive nano-systems for drug delivery in cancer therapy
Liu, J., Huang, Y., Kumar, A., Tan, A., Jin, S., Mozhi, A., & Liang, X.-J. (2014) · Biotechnology Advances · doi:10.1016/j.biotechadv.2013.11.009 · Cited by 1,121 · see citing works
Fleige, E., Quadir, M., & Haag, R. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.01.020 · Cited by 1,114 · see citing works
Recent advances and challenges in designing stimuli-responsive polymers
Liu, F., & Urban, M. W. (2009) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2009.10.002 · Cited by 1,006 · see citing works
Mechanisms and biomaterials in pH-responsive tumour targeted drug delivery: A review
Kanamala, M., Wilson, W. R., Yang, M., Palmer, B. D., & Wu, Z. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.01.061 · Cited by 1,004 · see citing works
Hybrid threshold adaptable quantum secret sharing scheme with reverse Huffman-Fibonacci-tree coding
Lai, H., Zhang, J., Luo, M., Pan, L., Pieprzyk, J., Xiao, F., & Orgun, M. A. (2016) · Scientific Reports · doi:10.1038/srep31350 · Cited by 814 · see citing works
Toward ‘smart’ nano-objects by self-assembly of block copolymers in solution
Rodríguez‐Hernández, J., Chécot, F., Gnanou, Y., & Lecommandoux, S. (2005) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2005.04.002 · Cited by 795 · see citing works
Wang, Y., Zhou, K., Huang, G., Hensley, C. T., Huang, X., Ma, X., Zhao, T., Sumer, B. D., DeBerardinis, R. J., & Gao, J. (2013) · Nature Materials · doi:10.1038/nmat3819 · Cited by 776 · see citing works
Smart polymers: Physical forms and bioengineering applications
Kumar, A., Srivastava, A., Galaev, I. Y., et al. (2007) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2007.05.003 · Cited by 743 · see citing works
Pillai, O., & Panchagnula, R. (2001) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(00)00227-1 · Cited by 711 · see citing works
pH-Responsive polymers: synthesis, properties and applications
Dai, S., Ravi, P., & Tam, K. C. (2008) · Soft Matter · doi:10.1039/b714741d · Cited by 705 · see citing works
Rodríguez‐Hernández, J., & Lecommandoux, S. (2005) · Journal of the American Chemical Society · doi:10.1021/ja043920g · Cited by 678 · see citing works
Zhang, J., Zou, X., Zhai, X., Huang, X., Caiping, J., & Holmes, M. J. (2018) · Food Chemistry · doi:10.1016/j.foodchem.2018.08.041 · Cited by 667 · see citing works
Magnetic responsive polymer composite materials
Thévenot, J., Oliveira, H., Sandre, O., & Lecommandoux, S. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60058k · Cited by 638 · see citing works
Zhang, X., Liu, Y., Yong, H., Qin, Y., Liu, J., & Liu, J. (2019) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2019.03.009 · Cited by 602 · see citing works
Amini, A., & Cheng, C. (2013) · Scientific Reports · doi:10.1038/srep03316 · Cited by 594 · see citing works
Hamaguchi, T., Matsumura, Y., Suzuki, M., Shimizu, K., Goda, R., Nakamura, I., Nakatomi, I., Yokoyama, M., Kataoka, K., & Kakizoe, T. (2005) · British Journal of Cancer · doi:10.1038/sj.bjc.6602479 · Cited by 565 · see citing works
pH-responsive polymer nanoparticles for drug delivery
Deirram, N., Zhang, C., Kermaniyan, S. S., Johnston, A. P. R., & Such, G. K. (2019) · Macromolecular Rapid Communications · doi:10.1002/marc.201800917 · Cited by 531 · see citing works
Functional nanomaterials based on block copolymer self-assembly
Kim, J. K., Yang, S. Y., Lee, Y., & Kim, Y. (2010) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2010.06.002 · Cited by 512 · see citing works
Novel pH-sensitive films containing curcumin and anthocyanins to monitor fish freshness
Chen, H., Zhang, M., Bhandari, B., et al. (2019) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2019.105438 · Cited by 496 · see citing works
pH-responsive chitosan-based film incorporated with alizarin for intelligent packaging applications
Ezati, P., & Rhim, J. (2019) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2019.105629 · Cited by 484 · see citing works
Design and development of polymeric micelles with cleavable links for intracellular drug delivery
Wei, H., Zhuo, R., & Zhang, X. (2012) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2012.07.002 · Cited by 475 · see citing works
Equilibrium swelling and kinetics of pH-responsive hydrogels: models, experiments, and simulations
De, S. K., Aluru, N. R., Johnson, B. P., et al. (2002) · Journal of Microelectromechanical Systems · doi:10.1109/jmems.2002.803281 · Cited by 463 · see citing works
Lee, E. S., Oh, K. T., Kim, D., Youn, Y. S., & Bae, Y. H. (2007) · Journal of Controlled Release · doi:10.1016/j.jconrel.2007.08.006 · Cited by 446 · see citing works
Zhu, C., Jung, S., Luo, S., Meng, F., Zhu, X., Park, T. G., & Zhong, Z. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.11.077 · Cited by 438 · see citing works
Marine Derived Polysaccharides for Biomedical Applications: Chemical Modification Approaches
d'Ayala, G. G., Malinconico, M., & Laurienzo, P. (2008) · Molecules · doi:10.3390/molecules13092069 · Cited by 434 · see citing works
Yong, H., Wang, X., Zhang, X., et al. (2019) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2019.03.012 · Cited by 397 · see citing works
Magnetic actuated pH-responsive hydrogel-based soft micro-robot for targeted drug delivery
Li, H., Go, G., Ko, S.-Y., et al. (2016) · Smart Materials and Structures · doi:10.1088/0964-1726/25/2/027001 · Cited by 396 · see citing works
Stimulus-responsive polymer brushes on surfaces: Transduction mechanisms and applications
Chen, T., Ferris, R. L., Zhang, J., et al. (2009) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2009.11.004 · Cited by 393 · see citing works
Stimuli-responsive polymers and nanomaterials for gene delivery and imaging applications
Shim, M. S., & Kwon, Y. J. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.01.018 · Cited by 384 · see citing works
Photo-responsive polymers: synthesis and applications
Bertrand, O., & Gohy, J. (2016) · Polymer Chemistry · doi:10.1039/c6py01082b · Cited by 371 · see citing works
Micro- and nanogels with labile crosslinks – from synthesis to biomedical applications
Zhang, X., Malhotra, S., Molina, M. A., & Haag, R. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00341a · Cited by 369 · see citing works
pH- and ion-sensitive polymers for drug delivery
Yoshida, T., Lai, T. C., Kwon, G. S., & Sako, K. (2013) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2013.821978 · Cited by 367 · see citing works
Synthesis and characterization of noble metal colloids in block copolymer micelles
Antonietti, M., Wenz, E., Bronstein, L. M., & Seregina, M. (1995) · Advanced Materials · doi:10.1002/adma.19950071205 · Cited by 358 · see citing works
Revisiting structure-property relationship of pH-responsive polymers for drug delivery applications
Bazban‐Shotorbani, S., Hasani‐Sadrabadi, M. M., Karkhaneh, A., Serpooshan, V., Jacob, K. I., Moshaverinia, A., & Mahmoudi, M. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.02.021 · Cited by 346 · see citing works
Matsumoto, A., Yoshida, R., & Kataoka, K. (2004) · Biomacromolecules · doi:10.1021/bm0345413 · Cited by 338 · see citing works
Ünsoy, G., Khodadust, R., Yalçın, S., Mutlu, P., & Gündüz, U. (2014) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2014.05.021 · Cited by 332 · see citing works
Polyethylenimine with acid-labile linkages as a biodegradable gene carrier
Kim, Y. H., Park, J. H., Lee, M., Kim, Y., Park, T. G., & Kim, S. W. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.11.008 · Cited by 328 · see citing works
Ph-responsive polymer–drug conjugates: design and progress
Pang, X., Jiang, Y., Xiao, Q., Leung, A. W., Hua, H., & Xu, C. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.12.024 · Cited by 317 · see citing works
Novel pH-sensitive citrate cross-linked chitosan film for drug controlled release
Shu, X. (2001) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(00)00582-2 · Cited by 314 · see citing works
Kim, D., Lee, E. S., Oh, K. T., Gao, Z. G., & Bae, Y. H. (2008) · Small · doi:10.1002/smll.200701275 · Cited by 313 · see citing works
Wu, W., Mitra, N. K., Yan, E. C. Y., & Zhou, S. (2010) · ACS Nano · doi:10.1021/nn1008319 · Cited by 309 · see citing works
Ko, J.-Y., Park, K., Kim, Y.-S., Kim, M.-S., Han, J. K., Kim, K., Park, R., Kim, I.-S., Song, H. K., Lee, D. S., et al. (2007) · Journal of Controlled Release · doi:10.1016/j.jconrel.2007.07.012 · Cited by 303 · see citing works
Swelling Behaviors of pH- and Salt-Responsive Cellulose-Based Hydrogels
Chang, C., He, M., Zhou, J., & Zhang, L. (2011) · Macromolecules · doi:10.1021/ma102801f · Cited by 301 · see citing works
Nanoprecipitation of Polymethylmethacrylate by Solvent Shifting:1. Boundaries
Aubry, J., Ganachaud, F., Addad, J. C., et al. (2009) · Langmuir · doi:10.1021/la803000e · Cited by 292 · see citing works
Min, K. H., Kim, J.-H., Bae, S. M., Shin, H., Kim, M.-S., Park, S.-J., Lee, H., Park, R., Kim, I.-S., Kim, K., et al. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.02.024 · Cited by 287 · see citing works
Ju, H. K., Kim, S. Y., & Lee, Y. M. (2001) · Polymer · doi:10.1016/s0032-3861(01)00143-4 · Cited by 285 · see citing works
Polyethylenimine-based nanocarriers in co-delivery of drug and gene: a developing horizon
Zakeri, A., Kouhbanani, M. A. J., Beheshtkhoo, N., et al. (2018) · Nano Reviews & Experiments · doi:10.1080/20022727.2018.1488497 · Cited by 282 · see citing works
Glutathione responsive polymers and their application in drug delivery systems
Quinn, J. F., Whittaker, M. R., & Davis, T. P. (2016) · Polymer Chemistry · doi:10.1039/c6py01365a · Cited by 281 · see citing works
Design and evaluation of novel pH-sensitive chitosan nanoparticles for oral insulin delivery
Makhlof, A., Tozuka, Y., & Takeuchi, H. (2010) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2010.12.007 · Cited by 277 · see citing works
Zhang, Y., Yang, C., Wang, W., Liu, J., Liu, Q., Huang, F., Chu, L., Gao, H., Liu, Q., Kong, D., et al. (2016) · Scientific Reports · doi:10.1038/srep21225 · Cited by 273 · see citing works
Chen, S., Wu, M., Lü, P., Gao, L., Yan, S., & Wang, S. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.01.231 · Cited by 273 · see citing works
Feng, C., Wang, Z., Jiang, C., Kong, M., Zhou, X., Li, Y., Cheng, X., & Chen, X. (2013) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2013.07.079 · Cited by 266 · see citing works
Roy, D., Cambre, J. N., & Sumerlin, B. S. (2009) · Chemical Communications · doi:10.1039/b900374f · Cited by 265 · see citing works
Plamper, F. A., Ballauff, M., & Müller, A. H. E. (2007) · Journal of the American Chemical Society · doi:10.1021/ja074720i · Cited by 260 · see citing works
Polymer micelles with cross-linked polyanion core for delivery of a cationic drug doxorubicin
Kim, J. O., Kabanov, A. V., & Bronich, T. K. (2009) · Journal of Controlled Release · doi:10.1016/j.jconrel.2009.04.019 · Cited by 255 · see citing works
Characterization of glucose-sensitive insulin release systems in simulated in vivo conditions
Traitel, T., Cohen, Y., & Kost, J. (2000) · Biomaterials · doi:10.1016/s0142-9612(00)00050-8 · Cited by 253 · see citing works
pH- and Temperature-Sensitive Hydrogel Nanoparticles with Dual Photoluminescence for Bioprobes
Zhao, Y., Shi, C., Yang, X., Shen, B., Sun, Y., Chen, Y., Xu, X., Sun, H., Yu, K., Yang, B., et al. (2016) · ACS Nano · doi:10.1021/acsnano.6b00770 · Cited by 245 · see citing works
Recent Development of pH-Responsive Polymers for Cancer Nanomedicine
Tang, H., Zhao, W., Yu, J., Li, Y., & Zhao, C. (2018) · Molecules · doi:10.3390/molecules24010004 · Cited by 244 · see citing works
Multi‐Stimuli‐Responsive Polymeric Materials
Guragain, S., Bastakoti, B. P., Malgras, V., et al. (2015) · Chemistry - A European Journal · doi:10.1002/chem.201501101 · Cited by 242 · see citing works
Sung, H., Sonaje, K., Liao, Z., Hsu, L., & Chuang, E. (2012) · Accounts of Chemical Research · doi:10.1021/ar200234q · Cited by 233 · see citing works
Photoresponsive Nanogels Based on Photocontrollable Cross-Links
He, J., Tong, X., & Zhao, Y. (2009) · Macromolecules · doi:10.1021/ma900665v · Cited by 220 · see citing works
Responsive hydrophobically associating polymers: a review of structure and properties
Tonge, S. R., & Tighe, B. J. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00223-x · Cited by 214 · see citing works
A transistor-like pH nanoprobe for tumour detection and image-guided surgery
Zhao, T., Huang, G., Li, Y., Yang, S.-C., Ramezani, S. M., Lin, Z., Wang, Y., Ma, X., Zeng, Z., Luo, M., et al. (2016) · Nature Biomedical Engineering · doi:10.1038/s41551-016-0006 · Cited by 207 · see citing works
Novel Amphiphilic Multi-Arm, Star-Like Block Copolymers as Unimolecular Micelles
Pang, X., Zhao, L., Akinç, M., Kim, J. K., & Lin, Z. (2011) · Macromolecules · doi:10.1021/ma200594j · Cited by 205 · see citing works
Tang, R., Ji, W., Panus, D., Palumbo, R. N., & Wang, C. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.12.005 · Cited by 202 · see citing works
Polymer-Grafted Cellulose Nanocrystals as pH-Responsive Reversible Flocculants
Kan, K. H. M., Li, J., Wijesekera, K. N., & Cranston, E. D. (2013) · Biomacromolecules · doi:10.1021/bm400752k · Cited by 202 · see citing works
Kang, S. I., & Bae, Y. H. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00409-1 · Cited by 198 · see citing works
A pH responsive complexation-based drug delivery system for oxaliplatin
Li, B., Meng, Z., Li, Q., Huang, X., Kang, Z., Dong, H., Chen, J., Sun, J., Dong, Y., Li, J., et al. (2017) · Chemical Science · doi:10.1039/c7sc01438d · Cited by 198 · see citing works
Vivek, R., Babu, V. N., Thangam, R., et al. (2013) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2013.05.018 · Cited by 194 · see citing works
Environmental pH-sensitive polymeric micelles for cancer diagnosis and targeted therapy
Gao, G., Li, Y., & Lee, D. S. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.11.012 · Cited by 190 · see citing works
Zarzar, L. D., Kim, P., & Aizenberg, J. (2011) · Advanced Materials · doi:10.1002/adma.201004231 · Cited by 188 · see citing works
Sonaje, K., Lin, K., Wey, S., Lin, C.-K., Yeh, T.-H., Nguyen, H.-N., Hsu, C., Yen, T., Juang, J., & Sung, H. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.05.042 · Cited by 187 · see citing works
Smart Actuators and Adhesives for Reconfigurable Matter
Ko, H., & Javey, A. (2017) · Accounts of Chemical Research · doi:10.1021/acs.accounts.6b00612 · Cited by 184 · see citing works
Ultrasound and pH Dually Responsive Polymer Vesicles for Anticancer Drug Delivery
Chen, W., & Du, J. (2013) · Scientific Reports · doi:10.1038/srep02162 · Cited by 182 · see citing works
Efficient Colorimetric pH Sensor Based on Responsive Polymer–Quantum Dot Integrated Graphene Oxide
Paek, K., Yang, H.-S., Lee, J., et al. (2014) · ACS Nano · doi:10.1021/nn406657b · Cited by 181 · see citing works
Binh, T., Fernandes, S., Balakrishnan, P. B., & Pellegrino, T. (2018) · Accounts of Chemical Research · doi:10.1021/acs.accounts.7b00549 · Cited by 176 · see citing works
Polymer Nanoparticles for Smart Drug Delivery
Bennet, D., & Kim, S. (2014) · InTech eBooks · doi:10.5772/58422 · Cited by 175 · see citing works
A cancer-recognizable MRI contrast agents using pH-responsive polymeric micelle
Kim, K. S., Park, W., Hu, J., Bae, Y. H., & Na, K. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.10.004 · Cited by 173 · see citing works
An overview of natural polymers for oral insulin delivery
Sonia, T. A., & Sharma, C. P. (2012) · Drug Discovery Today · doi:10.1016/j.drudis.2012.03.019 · Cited by 170 · see citing works
Sumaru, K., Kameda, M., Kanamori, T., et al. (2004) · Macromolecules · doi:10.1021/ma049661x · Cited by 168 · see citing works
Akar, E., Tağaç, A. A., & Seki, Y. (2012) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2012.07.043 · Cited by 168 · see citing works
Redox/pH dual-stimuli responsive camptothecin prodrug nanogels for “on-demand” drug delivery
Qu, Y., Chu, B., Wei, X., Lei, M., Hu, D., Zha, R., Zhong, L. X., Wang, M., Wang, F., & Qian, Z. (2019) · Journal of Controlled Release · doi:10.1016/j.jconrel.2019.01.016 · Cited by 166 · see citing works
Bütün, V., Armes, S. P., & Billingham, N. Ć. (2001) · Macromolecules · doi:10.1021/ma001550k · Cited by 162 · see citing works
Kwon, S. S., Kong, B. J., & Park, S. N. (2015) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2015.02.025 · Cited by 160 · see citing works
A naked-eye detection polyvinyl alcohol/cellulose-based pH sensor for intelligent packaging
Ding, L., Li, X., Hu, L., Zhang, Y., Jiang, Y., Mao, Z., Xu, H. Y., Wang, B., Feng, X., & Sui, X. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.115859 · Cited by 159 · see citing works
Yao, K. D., Peng, T., Feng, H. B., et al. (1994) · Journal of Polymer Science Part A Polymer Chemistry · doi:10.1002/pola.1994.080320702 · Cited by 153 · see citing works
Zhu, J., Tang, A., Law, L. P., et al. (2004) · Bioconjugate Chemistry · doi:10.1021/bc049895l · Cited by 147 · see citing works
Reversible bidirectional bending of hydrogel-based bilayer actuators
Li, X., Cai, X., Gao, Y., & Serpe, M. J. (2017) · Journal of Materials Chemistry B · doi:10.1039/c7tb00426e · Cited by 147 · see citing works
Ata, S., Rasool, A., Islam, A., Bibi, I., Rizwan, M., Azeem, M. K., Qureshi, M. A. U. R., & Iqbal, M. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.11.091 · Cited by 146 · see citing works
Time and pH dependent colon specific, pulsatile delivery of theophylline for nocturnal asthma
Mastiholimath, V. S., Dandagi, P. M., Jain, S. S., et al. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2006.07.045 · Cited by 145 · see citing works
Preparation of pH-responsive polymer membranes by self-organization
Hester, J. F., Olugebefola, S. C., & Mayes, A. M. (2002) · Journal of Membrane Science · doi:10.1016/s0376-7388(02)00317-4 · Cited by 143 · see citing works
Introduction to smart polymers and their applications
Aguilar, M. R., & Román, J. S. (2014) · Elsevier eBooks · doi:10.1533/9780857097026.1 · Cited by 142 · see citing works
Çetin, M., Atila, A., & Kadıoğlu, Y. (2010) · AAPS PharmSciTech · doi:10.1208/s12249-010-9489-6 · Cited by 142 · see citing works
Zeeshan, M., Ali, H., Khan, S., Khan, S. A., & Weigmann, B. (2019) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.12.074 · Cited by 140 · see citing works
pH-sensitive polymers for drug delivery
Huh, K. M., Kang, H. C., Lee, Y. J., & Bae, Y. H. (2012) · Macromolecular Research · doi:10.1007/s13233-012-0059-5 · Cited by 139 · see citing works
Recent progress and advances in redox-responsive polymers as controlled delivery nanoplatforms
Zhang, X., Han, L., Liu, M., Wang, K., Tao, L., Wan, Q., & Wei, Y. (2016) · Materials Chemistry Frontiers · doi:10.1039/c6qm00135a · Cited by 139 · see citing works
Jiang, J., Zhu, L.-P., Zhang, H., Zhu, B., & Xu, Y. (2014) · Journal of Membrane Science · doi:10.1016/j.memsci.2014.01.043 · Cited by 138 · see citing works
Cho, H. Y., Srinivasan, A., Hong, J., Hsu, E., Liu, S., Shrivats, A. R., Kwak, D. H., Bohaty, A. K., Paik, H., Hollinger, J. O., et al. (2011) · Biomacromolecules · doi:10.1021/bm2006455 · Cited by 135 · see citing works
Chitosan-Based Nanocarriers with pH and Light Dual Response for Anticancer Drug Delivery
Meng, L., Huang, W., Wang, D., Huang, X., Zhu, X., & Yan, D. (2013) · Biomacromolecules · doi:10.1021/bm400451v · Cited by 135 · see citing works
Connal, L. A., Li, Q., Quinn, J. F., et al. (2008) · Macromolecules · doi:10.1021/ma7019557 · Cited by 134 · see citing works
Temperature, pH and redox responsive cellulose based hydrogels for protein delivery
Dutta, S., Samanta, P., & Dhara, D. (2016) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2016.02.042 · Cited by 133 · see citing works
Sun, G., Chi, W., Zhang, C., et al. (2019) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2019.03.039 · Cited by 132 · see citing works
Shi, J., Liu, Y., Wang, L., Gao, J., Zhang, J., Yu, X., Ma, R., Liu, R., & Zhang, Z. (2013) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.10.037 · Cited by 131 · see citing works
Biodegradable pH-responsive hydrogels for controlled dual-drug release
Xu, L., Qiu, L., Sheng, Y., Sun, Y., Deng, L., Li, X., Bradley, M., & Zhang, R. (2018) · Journal of Materials Chemistry B · doi:10.1039/c7tb01851g · Cited by 128 · see citing works
Semisynthesis of a Controlled Stimuli-Responsive Alginate Hydrogel
(2009) · doi:10.1021/bm801316z · Cited by 124 · see citing works
pH-responsive polymers: properties, synthesis and applications
Reyes‐Ortega, F. (2014) · Elsevier eBooks · doi:10.1533/9780857097026.1.45 · Cited by 123 · see citing works
Bae, Y. M., Park, Y. I., Nam, S. H., Kim, J. H., Lee, K., Kim, H. M., Yoo, B., Choi, J. S., Lee, K. T., Hyeon, T., et al. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.08.039 · Cited by 123 · see citing works
Woraphatphadung, T., Sajomsang, W., Rojanarata, T., Ngawhirunpat, T., Tonglairoum, P., & Opanasopit, P. (2017) · AAPS PharmSciTech · doi:10.1208/s12249-017-0906-y · Cited by 123 · see citing works
Diblock copolymers with tunable pH transitions for gene delivery
Manganiello, M. J., Cheng, C., Convertine, A. J., Bryers, J. D., & Stayton, P. S. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.11.019 · Cited by 122 · see citing works
Johnson, R. P., Jeong, Y., Choi, E., Chung, C., Kang, D. H., Oh, S., Suh, H., & Kim, I. (2011) · Advanced Functional Materials · doi:10.1002/adfm.201102756 · Cited by 122 · see citing works
Wei, X., Luo, Q., Sun, L., Li, X., Zhu, H., Guan, P., Wu, M. C., Luo, K., & Gong, Q. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b02006 · Cited by 119 · see citing works
Cong, Y., Chen, K., Zhou, S., et al. (2015) · Journal of Materials Chemistry A · doi:10.1039/c5ta04986e · Cited by 118 · see citing works
Sadighian, S., Rostamizadeh, K., Hosseini‐Monfared, H., & Hamidi, M. (2014) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2014.03.001 · Cited by 118 · see citing works
HP55-coated capsule containing PLGA/RS nanoparticles for oral delivery of insulin
Wu, Z. M., Zhou, L., Guo, X. D., Jiang, W., Li, L., Qian, Y., Luo, K. Q., & Zhang, L. (2012) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2011.12.055 · Cited by 118 · see citing works
Development of enteric-coated calcium pectinate microspheres intended for colonic drug delivery
Maestrelli, F., Cirri, M., Corti, G., et al. (2008) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2007.12.004 · Cited by 118 · see citing works
Temperature, pH, and Glucose Responsive Gels via Simple Mixing of Boroxole- and Glyco-Based Polymers
Kotsuchibashi, Y., Agustin, R. V. C., Lu, J., et al. (2013) · ACS Macro Letters · doi:10.1021/mz400076p · Cited by 118 · see citing works
Miyazaki, M., Yuba, E., Hayashi, H., Harada, A., & Kono, K. (2017) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.7b00551 · Cited by 118 · see citing works
Aycan, D., & Alemdar, N. (2017) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2017.12.023 · Cited by 118 · see citing works
Quadruple-Stimuli-Sensitive Polymeric Nanocarriers for Controlled Release under Combined Stimulation
Cao, Z., Wu, H., Dong, J. N., & Wang, G. (2014) · Macromolecules · doi:10.1021/ma502003v · Cited by 116 · see citing works
Facile fabrication of redox/pH dual stimuli responsive cellulose hydrogel
Liu, H., Rong, L., Wang, B., et al. (2017) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2017.08.085 · Cited by 116 · see citing works
Almeida, H., Amaral, M. H., & Lobão, P. (2012) · Cited by 115 · see citing works
Smart composite hydrogel with pH-, ionic strength- and temperature-induced actuation
Shang, J., & Théato, P. (2018) · Soft Matter · doi:10.1039/c8sm01728j · Cited by 115 · see citing works
Photo, pH and redox multi-responsive nanogels for drug delivery and fluorescence cell imaging
Chen, S., Bian, Q., Wang, P., Zheng, X., Lv, L., Dang, Z., & Wang, G. (2017) · Polymer Chemistry · doi:10.1039/c7py01424d · Cited by 114 · see citing works
Review: doxorubicin delivery systems based on chitosan for cancer therapy
Tan, M. L., Choong, P., & Dass, C. R. (2009) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp.61.02.0001 · Cited by 112 · see citing works
Stability of responsive polymer–protein bioconjugates
Shakya, A. K., Sami, H., Srivastava, A., & Kumar, A. (2010) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2010.01.003 · Cited by 110 · see citing works
Insulin-Loaded pH-Sensitive Hyaluronic Acid Nanoparticles Enhance Transcellular Delivery
Han, L., Zhao, Y., Yin, L., et al. (2012) · AAPS PharmSciTech · doi:10.1208/s12249-012-9807-2 · Cited by 110 · see citing works
Absorbable and Biodegradable Polymers
Shalaby, S. W., & Burg, K. J. L. (2003) · CRC Press eBooks · doi:10.1201/9780203493014 · Cited by 110 · see citing works
Jiang, F., Chen, S., Cao, Z., & Wang, G. (2015) · Polymer · doi:10.1016/j.polymer.2015.12.027 · Cited by 109 · see citing works
A pH-, thermo-, and glucose-, triple-responsive hydrogels: Synthesis and controlled drug delivery
Wang, L., Liu, M., Gao, C., et al. (2009) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2009.11.007 · Cited by 107 · see citing works
Gao, G., Im, G. H., Kim, M.-S., et al. (2010) · Small · doi:10.1002/smll.200902317 · Cited by 107 · see citing works
Orally disintegrating dosage forms and taste-masking technologies; 2010
Douroumis, D. (2011) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2011.566553 · Cited by 107 · see citing works
Review: doxorubicin delivery systems based on chitosan for cancer therapy
Tan, M. L., Choong, P., & Dass, C. R. (2009) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp/61.02.0001 · Cited by 106 · see citing works
Supramolecular control over thermoresponsive polymers
de la Rosa, V. R., Woisel, P., & Hoogenboom, R. (2015) · Materials Today · doi:10.1016/j.mattod.2015.06.013 · Cited by 105 · see citing works
Shalviri, A., Raval, G., Prasad, P., Chan, C., Liu, Q., Heerklotz, H. H., Rauth, A. M., & Wu, X. Y. (2012) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2012.09.001 · Cited by 101 · see citing works
Edible Polymers for Essential Oils Encapsulation: Application in Food Preservation
Froiio, F., Mosaddik, A., Morshed, M. T., Paolino, D., Fessi, H., & Elaı̈ssari, A. (2019) · Industrial & Engineering Chemistry Research · doi:10.1021/acs.iecr.9b02418 · Cited by 101 · see citing works
Li, P., Tan, A., Prestidge, C. A., Nielsen, H. M., & Müllertz, A. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2014.10.039 · Cited by 100 · see citing works
Anticancer nanoparticulate polymer‐drug conjugate
Feng, Q., & Tong, R. (2016) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10033 · Cited by 99 · see citing works
Enzyme/pH dual sensitive polymeric nanoparticles for targeted drug delivery to the inflamed colon
Naeem, M., Kim, W., Cao, J., Jung, Y., & Yoo, J. (2014) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2014.09.026 · Cited by 98 · see citing works
Longhi, A., Ferrari, S. M., Bacci, G., et al. (2007) · Anti-Cancer Drugs · doi:10.1097/cad.0b013e32803d36fe · Cited by 97 · see citing works
Shen, Y., Zhan, Y., Tang, J., Xu, P., Johnson, P. A., Radosz, M., Kirk, E. A. V., & Murdoch, W. J. (2008) · AIChE Journal · doi:10.1002/aic.11600 · Cited by 97 · see citing works
Photo-triggered polymer nanomedicines: From molecular mechanisms to therapeutic applications
Beauté, L., McClenaghan, N. D., & Lecommandoux, S. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.12.010 · Cited by 96 · see citing works
Chim, Y. T. A., Lam, J. K. W., Ma, Y., Armes, S. P., Lewis, A. L., Roberts, C. J., Stolnik, S., Tendler, S. J. B., & Davies, M. C. (2005) · Langmuir · doi:10.1021/la047480i · Cited by 94 · see citing works
The removal of heavy metal ions from aqueous solutions by novel pH-sensitive hydrogels
Yıldız, U., Kemik, Ö. F., & Hazer, B. (2010) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2010.07.055 · Cited by 93 · see citing works
Kim, Y. K., Kim, E.-J., Lim, J. H., Cho, H. K., Hong, W. J., Jeon, H. H., & Chung, B. G. (2019) · Nanoscale Research Letters · doi:10.1186/s11671-019-2909-y · Cited by 93 · see citing works
Thermo- and pH dual responsive polymeric micelles and nanoparticles
Kalhapure, R. S., & Renukuntla, J. (2018) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2018.07.016 · Cited by 91 · see citing works
Essential Oils-Loaded Polymer Particles: Preparation, Characterization and Antimicrobial Property
Froiio, F., Ginot, L., Paolino, D., Lebaz, N., Bentaher, A., Fessi, H., & Elaı̈ssari, A. (2019) · Polymers · doi:10.3390/polym11061017 · Cited by 91 · see citing works
Self-citationJelvehgari, M., Zakeri‐Milani, P., Siahi-Shadbad, M. R., et al. (2010) · AAPS PharmSciTech · doi:10.1208/s12249-010-9488-7 · Cited by 90 · see citing works
Hyper/highly-branched polymers by radical polymerisations
England, R., & Rimmer, S. (2010) · Polymer Chemistry · doi:10.1039/c0py00154f · Cited by 89 · see citing works
Redox and pH Dual Responsive Polymer Based Nanoparticles for In Vivo Drug Delivery
Ang, C. Y., Tan, S. Y., Teh, C., Lee, J. M., Wong, M. F. E., Qu, Q., Qing, P. L., Li, M., Zhang, Y., Korzh, V. P., et al. (2016) · Small · doi:10.1002/smll.201602379 · Cited by 88 · see citing works
Zhou, Z., Li, L., Yang, Y., Xu, X., & Huang, Y. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.04.059 · Cited by 86 · see citing works
pH-Sensitive Polymers for Drug Delivery
(2005) · CRC Press eBooks · doi:10.1201/9780849348129-6 · Cited by 86 · see citing works
pH-Responsive Nanostructures Assembled from Amphiphilic Block Copolymers
Chen, X., Wayland, B. B., Fryd, M. M., et al. (2006) · Macromolecules · doi:10.1021/ma060881f · Cited by 85 · see citing works
Ekici, S. (2010) · Journal of Materials Science · doi:10.1007/s10853-010-5158-0 · Cited by 84 · see citing works
Glucose- and pH-Responsive Nanogated Ensemble Based on Polymeric Network Capped Mesoporous Silica
Tan, L., Yang, M., Wu, H., et al. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b00631 · Cited by 84 · see citing works
Hyaluronic-Acid-Based pH-Sensitive Nanogels for Tumor-Targeted Drug Delivery
Luan, S., Zhu, Y., Wu, X., Wang, Y., Liang, F., & Song, S. (2017) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.7b00444 · Cited by 84 · see citing works
Jiang, X., Lu, G., Feng, C., et al. (2013) · Polymer Chemistry · doi:10.1039/c3py00415e · Cited by 82 · see citing works
Thambi, T., Deepagan, V. G., Yoo, C., & Park, J. H. (2011) · Polymer · doi:10.1016/j.polymer.2011.08.024 · Cited by 79 · see citing works
Smart Materials for Tissue Engineering
(2016) · RSC smart materials · doi:10.1039/9781782626756 · Cited by 79 · see citing works
Yu, F., Yang, L., Liu, C. S., et al. (2015) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2015.02.055 · Cited by 77 · see citing works
Glucose and pH dual-responsive concanavalin A based microhydrogels for insulin delivery
Yin, R., Tong, Z., Yang, D., et al. (2011) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2011.09.014 · Cited by 76 · see citing works
Sakamoto, C., Okada, Y., Kanazawa, H., et al. (2003) · Journal of Chromatography A · doi:10.1016/j.chroma.2003.09.010 · Cited by 75 · see citing works
Liu, H., Yang, S., Liu, Y., et al. (2019) · Journal of Membrane Science · doi:10.1016/j.memsci.2019.03.010 · Cited by 75 · see citing works
Vamvakaki, M., Papoutsakis, L., Katsamanis, V., et al. (2004) · Faraday Discussions · doi:10.1039/b403414g · Cited by 73 · see citing works
Bioinspired Actuators Based on Stimuli‐Responsive Polymers
Cui, H., Zhao, Q., Wang, Y., & Du, X. (2019) · Chemistry - An Asian Journal · doi:10.1002/asia.201900292 · Cited by 73 · see citing works
Stimuli-Responsive Interfaces Using Random Polyampholyte Brushes
Sanjuan, S., & Tran, Y. (2008) · Macromolecules · doi:10.1021/ma8018798 · Cited by 72 · see citing works
Stimuli-Responsive Membranes through Sustainable Aqueous Phase Separation
Willott, J. D., Nielen, W. M., & de Vos, W. M. (2019) · ACS Applied Polymer Materials · doi:10.1021/acsapm.9b01006 · Cited by 70 · see citing works
Sun, S., Yamamoto, H., Kawashimà, Y., et al. (2015) · International Journal of Nanomedicine · doi:10.2147/ijn.s81715 · Cited by 68 · see citing works
Li, Z., Wang, Y., Wu, N., Qichun, C., & Wu, K. M. (2012) · Environmental Science and Pollution Research · doi:10.1007/s11356-012-0973-2 · Cited by 67 · see citing works
Coated pellets for oral colon delivery
Palugan, L., Cerea, M., Zema, L., et al. (2015) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2014.12.003 · Cited by 66 · see citing works
Montha, W., Maneeprakorn, W., Buatong, N., Tang, I., & Pon‐On, W. (2015) · Materials Science and Engineering C · doi:10.1016/j.msec.2015.09.098 · Cited by 66 · see citing works
Ma, Z., Jia, X., Zhang, G., Hu, J., Zhang, X., Liu, Z., Wang, H.-Y., & Zhou, F. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf401102a · Cited by 65 · see citing works
pH responsive fluorescence nanoprobe imaging of tumors by sensing the acidic microenvironment
Wang, L., & Li, C. (2011) · Journal of Materials Chemistry · doi:10.1039/c1jm12072g · Cited by 64 · see citing works
Liu, J., Detrembleur, C., Debuigne, A., et al. (2013) · Journal of Materials Chemistry B · doi:10.1039/c3tb21272f · Cited by 64 · see citing works
Ayano, E., Nambu, K., Sakamoto, C., et al. (2006) · Journal of Chromatography A · doi:10.1016/j.chroma.2006.01.068 · Cited by 62 · see citing works
Liu, L., Zhang, Y., Yu, S., Zhang, Z., He, C., & Chen, X. (2018) · Biomacromolecules · doi:10.1021/acs.biomac.8b00215 · Cited by 62 · see citing works
Stimuli-responsive materials in analytical separation
Lorenzo, R. A., Carro, A. M., Concheiro, Á., et al. (2015) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-015-8679-1 · Cited by 61 · see citing works
Obeidat, W. M., & Price, J. C. (2006) · Journal of Microencapsulation · doi:10.1080/02652040500435337 · Cited by 60 · see citing works
Eldin, M. S. M., El-Sherif, H. M., Soliman, E. A., et al. (2011) · Journal of Applied Polymer Science · doi:10.1002/app.33283 · Cited by 60 · see citing works
Curcio, A., Marotta, R., Riedinger, A., et al. (2012) · Chemical Communications · doi:10.1039/c2cc17223b · Cited by 59 · see citing works
Light and pH Dual‐Degradable Triblock Copolymer Micelles for Controlled Intracellular Drug Release
Jin, Q., Cai, T., Han, H., Wang, H., Wang, Y., & Ji, J. (2014) · Macromolecular Rapid Communications · doi:10.1002/marc.201400171 · Cited by 59 · see citing works
Cheng, Y., Huang, C., Yang, D., et al. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb02242a · Cited by 59 · see citing works
Hyaluronated nanoparticles with pH- and enzyme-responsive drug release properties
Kim, S. W., Oh, K. T., Youn, Y. S., & Lee, E. S. (2014) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2014.01.017 · Cited by 57 · see citing works
Li, C., Zhou, K., Chen, D., et al. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s183479 · Cited by 57 · see citing works
Zhou, Y., Zhang, Q., & Luo, Z. (2014) · Langmuir · doi:10.1021/la402948s · Cited by 56 · see citing works
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<scp>pH</scp> ‐responsive polymers for drug delivery: Trends and opportunities
Singh, J., & Nayak, P. (2023) · Journal of Polymer Science · doi:10.1002/pol.20230403 · Cited by 327 · see citing works
Bami, M. S., Raeisi Estabragh, M. A., Khazaeli, P., Ohadi, M., & Dehghannoudeh, G. (2022) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2021.102987 · Cited by 101 · see citing works
pH stimuli-responsive hydrogels from non-cellulosic biopolymers for drug delivery.
Vegad, U., Patel, M., Khunt, D., Zupančič, O., Chauhan, S., & Paudel, A. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1270364 · Cited by 85 · see citing works
“In addition, the incorporation of these hydrogels into state-of-the-art imaging and monitoring technologies, such as pH monitoring in real-time or drug administration guided by imaging, has the potential to enhance the accuracy and efficacy of therapies, therefore addressing significant deficiencies in existing medica…”
Background
- Authors
- Ofridam, F., Tarhini, M., Lebaz, N., Gagnière, É., Mangin, D., & Elaissari, A.
- Affiliations
- Lyon 1 Université (FR)
- Univ Lyon, University Claude Bernard Lyon 1, CNRS, ISA UMR 5280 Villeurbanne France
- Corresponding author
- Lebaz, Noureddine
- Venue
- Polymers for Advanced Technologies
- Publisher
- Wiley
- Published
- 2021-02-03
- Volume
- 32
- Issue
- 4
- Pages
- 1455-1484
- ISSN
- 1042-7147 (ISSN-L)
- 1099-1581
- OpenAlex
- W3126331913
- Cited by
- 286
- References
- 288
- Citations by year
- 2026: 37 · 2025: 68 · 2024: 62 · 2023: 52 · 2022: 56 · 2021: 10 · 2020: 1
- FWCI
- 14.29
- Type
- journal article
- Language
- en
- Open access
- green
- hal.science
- Licence
- Locations
- Polymers for Advanced Technologies (publishedVersion)
- HAL (submittedVersion, other-oa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Physical Sciences › Chemistry › Organic Chemistry › Advanced Polymer Synthesis and Characterization
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
- Keywords
- pH-responsive polymers, stimuli-responsive materials, polymer classification, drug delivery, targeted drug delivery, sensing and actuation, membrane functionalization, separation processes, agricultural applications, food industry applications, chemical industry applications, polymer synthesis
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