Internet-based guided self-help for parents of children on cancer treatment: a randomized controlled trial
Open accessAbstract
OBJECTIVE: The aim of the study was to investigate the feasibility and preliminary efficacy of an Internet-based guided self-help intervention for posttraumatic stress symptoms (PTSS) and related symptoms in parents of children on cancer treatment. METHODS: Parents of children on cancer treatment, who fulfilled the modified symptom criteria on the PTSD Checklist, were randomly allocated to the intervention or to a wait-list control condition. The intervention group accessed a 10-week guided self-help program via the Internet based on principles from cognitve behavior therapy. The primary outcome PTSS and the secondary outcomes depression and anxiety were assessed by self-report preintervention and postintervention. RESULTS: Seven hundred forty-seven parents were approached and informed about the study, 92 were assessed for eligibility, and 58 were included and randomized to the intervention (n = 31) or wait list (n = 27). Eightteen participants completed the intervention. Intention-to-treat analyses indicated a significant effect of the intervention on PTSS with a large between-group effect size at postassessment (Cohen's d = 0.88). The intervention group reported reductions in PTSS with a large within-group effect size (d = 1.62) compared with a minimal reduction in the wait-list group (d = 0.09). There was a significant intervention effect on depression and anxiety and reductions in the intervention group with large within-group effect sizes (d = 0.85-1.09). CONCLUSIONS: Findings indicate a low enrollment rate and considerable attrition but also that Internet-based guided self-help shows promise for parents of children on cancer treatment who report a high level of PTSS and would like to take part in an Internet-based intervention.
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An internet-administered psychological, self-help intervention is effective in reducing symptoms of anxiety, depression and post-traumatic stress (PTSS) among parents of children recently diagnosed with cancer, with improvements maintained at 1-year follow-up.
“We have shown an internet-administered psychological, self-help intervention to be effective in reducing symptoms of anxiety, depression and post-traumatic stress (PTSS) among parents of children recently diagnosed with cancer,11 with improvements maintained at 1-year follow-up.12”
From Study protocol for a feasibility study of an internet-administered, guided, CBT-based, self-help intervention (ENGAGE) for parents of children previously treated for cancer (2018) · cites this paper as [11]
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Experimental — accuracy not yet measuredApproximately 30% of parents with a need for psychological support are expected to potentially consent to participate.
“Approximately 30% of these (216/720) are expected to potentially consent.11 12 18”
From Study protocol for a feasibility study of an internet-administered, guided, CBT-based, self-help intervention (ENGAGE) for parents of children previously treated for cancer (2018) · cites this paper as [11]
The Discussion (page unavailable) reports that 26% of approached parents expressed interest, close to the cited estimate of approximately 30%. But they consented to be contacted again, not to participate in the trial, and their need for psychological support was not established; the Results report that only 58 of 747 approached parents were randomized. (LLM, conf=0.86)
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Qin, Z., Lan, J., Zou, Q., He, H., Guo, Y., Yin, J. F., & Wang, J. (2026) · Journal of Family Theory & Review · doi:10.1111/jftr.70085
- Authors
- Cernvall, M., Carlbring, P., Ljungman, L., Ljungman, G., & Essen, L.
- Affiliations
- Uppsala University (SE)
- Stockholm University (SE)
- Clinical Psychology in Healthcare, Department of Public Health and Caring Sciences Uppsala University Uppsala Sweden
- Corresponding author
- Cernvall, Martin
- Venue
- Psycho-Oncology
- Publisher
- Wiley
- Published
- 2015-03
- Volume
- 24
- Issue
- 9
- Pages
- 1152-1158
- ISSN
- 1057-9249 (ISSN-L)
- 1099-1611
- PMC
- PMC5024013
- OpenAlex
- W1801224765
- Cited by
- 61
- References
- 38
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 3 · 2023: 3 · 2022: 4 · 2021: 8 · 2020: 5 · 2019: 9 · 2018: 8 · 2017: 5 · 2016: 3 · 2015: 4 · 2012: 1
- FWCI
- 10.81
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Psycho-Oncology (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Uppsala University Publications (Uppsala University) (submittedVersion, other-oa)
- Funders
- Swedish Research Council (K2008-70X-20836-01-3, K2011-70X-20836-04-4)
- Swedish Cancer Society (2010/276)
- Swedish Childhood Cancer Foundation (PROJ08/010, PRO12/028)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Keywords
- posttraumatic stress symptoms, parents of children with cancer, childhood cancer, cognitive behavioral therapy, depression, anxiety, feasibility, attrition, enrollment rates
- MeSH terms
- Adolescent, Adult, Child, Child, Preschool, Feasibility Studies, Female, Humans, Male, Middle Aged, Neoplasms, Parents, Stress Disorders, Post-Traumatic, Therapy, Computer-Assisted, Internet, Self Report
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