Cited by 1,104Advanced Sensor and Energy Harvesting MaterialsNanomaterials and Printing TechnologiesNeuroscience and Neural Engineering

Recent Advances in Flexible and Stretchable Bio‐Electronic Devices Integrated with Nanomaterials

Choi, Suji, Lee, Hyunjae, Ghaffari, Roozbeh, Hyeon, Taeghwan, Kim, Dae‐Hyeong·2016·Advanced Materials

Abstract

Flexible and stretchable electronics and optoelectronics configured in soft, water resistant formats uniquely address seminal challenges in biomedicine. Over the past decade, there has been enormous progress in the materials, designs, and manufacturing processes for flexible/stretchable system subcomponents, including transistors, amplifiers, bio‐sensors, actuators, light emitting diodes, photodetector arrays, photovoltaics, energy storage elements, and bare die integrated circuits. Nanomaterials prepared using top‐down processing approaches and synthesis‐based bottom‐up methods have helped resolve the intrinsic mechanical mismatch between rigid/planar devices and soft/curvilinear biological structures, thereby enabling a broad range of non‐invasive, minimally invasive, and implantable systems to address challenges in biomedicine. Integration of therapeutic functional nanomaterials with soft bioelectronics demonstrates therapeutics in combination with unconventional diagnostics capabilities. Recent advances in soft materials, devices, and integrated systems are reviewes, with representative examples that highlight the utility of soft bioelectronics for advanced medical diagnostics and therapies.

Integrity signals

Registry

Crossref · 10.1002/adma.201504150

Cites

113 of 113 references verified0 citation errors · 0 not checkable

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  • The personality of the patient influences the efficacy and perceived performance of the wearable device.

    “Additionally, the personality of the patient influences the efficacy and perceived performance of the wearable device.255”

    From Wearables in Medicine (2018) · cites this paper as [255]

  • Both degradation time and rate of degradation can be adjusted by modulating thickness between active and encapsulation layers, allowing devices to remain in vivo from days, weeks, to months depending on applications.

    “Both the degradation time and rate of degradation can be adjusted by modulating the thickness between the active and encapsulation layers, allowing the devices to remain in vivo from days, weeks, to months depending on the applications (Choi et al., 2016).”
  • Recently one research trend of the neural interface is to combine with neural tissue or biodegradable materials for long-term use or removing additional surgery.

    “Novel approaches were demonstrated previously, and recently one of the research trends of the neural interface is to combine with neural tissue or biodegradable materials for long-term use or removing additional surgery.21,111,112”
  • The emergence of IC fabrication strategies, flexible electronics, device design, and e-garments has revolutionized the development of soft electronics and biological and chemical sensor technologies toward advancing sports medicine.

    “The emergence of IC fabrication strategies, flexible electronics, device design, and e-garments has revolutionized the development of soft electronics and biological and chemical sensor technologies toward advancing sports medicine.123–127”

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Authors
Choi, S., Lee, H., Ghaffari, R., Hyeon, T., & Kim, D.
Affiliations
  • Seoul National University (KR)
  • MC10 (United States) (US)
Corresponding author
Kim, Dae‐Hyeong
Venue
Advanced Materials
Publisher
Wiley
Published
2016-01-18
Volume
28
Issue
22
Pages
4203-4218
ISSN
  • 0935-9648 (ISSN-L)
  • 1521-4095
OpenAlex
W2276037417
Cited by
1,104
References
114
Citations by year
2026: 42 · 2025: 76 · 2024: 91 · 2023: 82 · 2022: 112 · 2021: 145 · 2020: 154 · 2019: 159 · 2018: 129 · 2017: 87 · 2016: 27
FWCI
64.48
Type
journal article
Language
en
Open access
closed
Locations
  • Advanced Materials (publishedVersion)
  • PubMed (publishedVersion)
  • Seoul National University Open Repository (Seoul National University) (submittedVersion)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
  • Physical Sciences › Engineering › Electrical and Electronic Engineering › Nanomaterials and Printing Technologies
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
Keywords
flexible electronics, stretchable electronics, bioelectronics, nanomaterials, soft materials, biomedical implants, non-invasive diagnosis, medical therapeutics, biosensors, photodetectors, photovoltaics, energy storage, actuators, light-emitting diodes, integrated circuits
MeSH terms
Prostheses and Implants, Nanostructures, Electrical Equipment and Supplies

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