Molecular Cloning of the Human ATP-Binding Cassette Transporter 1 (hABC1): Evidence for Sterol-Dependent Regulation in Macrophages

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

Bodzioch, M., Orsó, E., Klucken, J., Langmann, T., Böttcher, A., Diederich, W., Drobnik, W., Barlage, S., Büchler, C., Porsch-Özcürümez, M., et al. (1999) · Nature Genetics · doi:10.1038/11914 · Cited by 1,512

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

Rust, S., Rosier, M., Funke, H., Real, J., Amoura, Z., Piette, J.-C., Deleuze, J.-F., Brewer, H. B., Duverger, N., Denèfle, P., et al. (1999) · Nature Genetics · doi:10.1038/11921 · Cited by 1,433

A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis

Chawla, A., Boisvert, W. A., Lee, C.-H., Laffitte, B. A., Barak, Y., Joseph, S. B., Liao, D., Nagy, L., Edwards, P. A., Curtiss, L. K., et al. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00164-2 · Cited by 1,347

The human ATP-binding cassette (ABC) transporter superfamily

Dean, M., Hamon, Y., & Chimini, G. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31588-1 · Cited by 1,302

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα

Venkateswaran, A., Laffitte, B. A., Joseph, S. B., Mak, P. A., Wilpitz, D. C., Edwards, P. A., & Tontonoz, P. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.200367697 · Cited by 1,005

The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

Lawn, R. M., Wade, D. P., Garvin, M. R., Wang, X., Schwartz, K., Porter, J. G., Seilhamer, J. J., Vaughan, A. M., & Oram, J. F. (1999) · Journal of Clinical Investigation · doi:10.1172/jci8119 · Cited by 724

Functionally Defective High-Density Lipoprotein: A New Therapeutic Target at the Crossroads of Dyslipidemia, Inflammation, and Atherosclerosis

Kontush, A., & Chapman, M. J. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.3.1 · Cited by 647

Intestinal ABCA1 directly contributes to HDL biogenesis in vivo

Brunham, L. R. (2006) · Journal of Clinical Investigation · doi:10.1172/jci27352 · Cited by 519

ATP-Binding Cassette Cholesterol Transporters and Cardiovascular Disease

Oram, J. F., & Vaughan, A. M. (2006) · Circulation Research · doi:10.1161/01.res.0000250171.54048.5c · Cited by 411

Increased Atherosclerosis in Hyperlipidemic Mice With Inactivation of ABCA1 in Macrophages

Aiello, R. J., Brees, D., Bourassa, P.-A., Royer, L., Lindsey, S., Coskran, T., Haghpassand, M., & Francone, O. L. (2002) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000014804.35824.da · Cited by 390

Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues

Van Eck, M., Bos, I. S. T., Kaminski, W. E., Orsó, E., Rothe, G., Twisk, J., Böttcher, A., Van Amersfoort, E. S., Christiansen-Weber, T. A., Fung-Leung, W.-P., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092327399 · Cited by 348

Human ABCA1 BAC Transgenic Mice Show Increased High Density Lipoprotein Cholesterol and ApoAI-dependent Efflux Stimulated by an Internal Promoter Containing Liver X Receptor Response Elements in Intron 1

Singaraja, R. R., Bocher, V., James, E. R., Clee, S. M., Zhang, L.-H., Leavitt, B. R., Tan, B., Brooks-Wilson, A., Kwok, A., Bissada, N., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102503200 · Cited by 194

Sources of eicosanoid precursor fatty acid pools in tissues

Zhou, L., & Nilsson, Å. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32206-9 · Cited by 184

Cholesterol in islet dysfunction and type 2 diabetes

Brunham, L. R., Kruit, J. K., Verchere, C. B., & Hayden, M. R. (2008) · Journal of Clinical Investigation · doi:10.1172/jci33296 · Cited by 158

Expression of ABCG1, but not ABCA1, correlates with cholesterol release by cerebellar astroglia

Karten, B., Campenot, R. B., Vance, D. E., & Vance, J. E. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m508915200 · Cited by 124

Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast–like Cells Is Driven by an Unfolded Protein Response

Chattopadhyay, A., Kwartler, C. S., Kaw, K., Li, Y., Kaw, A., Chen, J., LeMaire, S. A., Shen, Y. H., & Milewicz, D. M. (2021) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.120.315164 · Cited by 123

The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration

Koldamova, R., Fitz, N. F., & Lefterov, I. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2010.02.010 · Cited by 102

Acidification of the intimal fluid: the perfect storm for atherogenesis

Öörni, K., Rajamäki, K., Nguyen, S. D., Lähdesmäki, K., Plihtari, R., Lee-Rueckert, M., & Kovanen, P. T. (2015) · Journal of Lipid Research · doi:10.1194/jlr.r050252 · Cited by 101

ATP binding cassette transporter ABCA1 modulates the secretion of apolipoprotein E from human monocyte‐derived macrophages

Von Eckardstein, A., Langer, C., Engel, T., Schaukal, I., Cignarella, A., Reinhardt, J., Lorkowski, S., Li, Z., Zhou, X., Cullen, P., et al. (2001) · The FASEB Journal · doi:10.1096/fj.00-0798com · Cited by 95

Treadmill exercise enhances ABCA1 expression in rat liver

Ghanbari-Niaki, A., Khabazian, B. M., Hossaini-Kakhak, S. A., Rahbarizadeh, F., & Hedayati, M. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.07.100 · Cited by 94

Phospholipid transfer protein is present in human atherosclerotic lesions and is expressed by macrophages and foam cells

Desrumaux, C. M., Mak, P. A., Boisvert, W. A., Masson, D., Stupack, D., Jauhiainen, M., Ehnholm, C., & Curtiss, L. K. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m200281-jlr200 · Cited by 75

Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer’s disease

Reiss, A. B., Siller, K. A., Rahman, M. M., Chan, E. S. L., Ghiso, J., & de Leon, M. J. (2004) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2003.11.009 · Cited by 73

The ABCs of Sterol Transport

Plummer, A. M., Culbertson, A. T., & Liao, M. (2021) · Annual Review of Physiology · doi:10.1146/annurev-physiol-031620-094944 · Cited by 60

Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus

Akram, A., Schmeidler, J., Katsel, P., Hof, P. R., & Haroutunian, V. (2010) · Brain Research · doi:10.1016/j.brainres.2010.01.006 · Cited by 50

Apolipoprotein A-I-stimulated Apolipoprotein E Secretion from Human Macrophages Is Independent of Cholesterol Efflux

Kockx, M., Rye, K.-A., Gaus, K., Quinn, C. M., Wright, J., Sloane, T., Sviridov, D., Fu, Y., Sullivan, D., Burnett, J. R., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m401177200 · Cited by 47

Hepatic ATP-Binding Cassette Transporter A1 Is a Key Molecule in High-Density Lipoprotein Cholesteryl Ester Metabolism in Mice

Singaraja, R. R., Stahmer, B., Brundert, M., Merkel, M., Heeren, J., Bissada, N., Kang, M., Timmins, J. M., Ramakrishnan, R., Parks, J. S., et al. (2006) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000229219.13757.a2 · Cited by 33

Human cerebrospinal fluid contains diverse lipoprotein subspecies enriched in proteins implicated in central nervous system health

Merrill, N. J., Davidson, W. S., He, Y., Díaz Ludovico, I., Sarkar, S., Berger, M. R., McDermott, J. E., Van Eldik, L. J., Wilcock, D. M., Monroe, M. E., et al. (2023) · Science Advances · doi:10.1126/sciadv.adi5571 · Cited by 27

An inhibitor of acylCoA: cholesterol acyltransferase increases expression of ATP-binding cassette transporter A1 and thereby enhances the ApoA-I-mediated release of cholesterol from macrophages

Sugimoto, K., Tsujita, M., Wu, C.-A., Suzuki, K., & Yokoyama, S. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2003.12.005 · Cited by 24

The Effect of Regular Aerobic Exercise on Reverse Cholesterol Transport A1 and Apo Lipoprotein A-I Gene Expression in Inactive Women

Tofighi, A., Rahmani, F., Jamali Qarakhanlou, B., & Babaei, S. (2015) · Iranian Red Crescent Medical Journal · doi:10.5812/ircmj.17(4)2015.26321 · Cited by 22

Impaired ATP‐binding cassette transporter A1‐mediated sterol efflux from oxidized LDL‐loaded macrophages

Favari, E., Zimetti, F., Bortnick, A. E., Adorni, M. P., Zanotti, I., Canavesi, M., & Bernini, F. (2005) · FEBS Letters · doi:10.1016/j.febslet.2005.10.042 · Cited by 22