NAD + /NADH and NADP + /NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences

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Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor

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Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

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Reactive Oxygen Radicals in Signaling and Damage in the Ischemic Brain

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The Sir2 Family of Protein Deacetylases

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The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

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The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors

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Mammalian SIRT1 Represses Forkhead Transcription Factors

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Mechanisms of Cell Death in Oxidative Stress

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Nitric Oxide Activation of Poly(ADP-Ribose) Synthetase in Neurotoxicity

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S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

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Increased Nuclear NAD Biosynthesis and SIRT1 Activation Prevent Axonal Degeneration

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Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors

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Role of Oxidants in Ischemic Brain Damage

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Cloning and Characterization of the cDNA Encoding a Novel Human pre-B-Cell Colony-enhancing Factor

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Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

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The NAD Biosynthesis Pathway Mediated by Nicotinamide Phosphoribosyltransferase Regulates Sir2 Activity in Mammalian Cells

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NAD+ metabolism in health and disease

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Necrotic death as a cell fatePreprint

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NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells

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A Topoisomerase IIß-Mediated dsDNA Break Required for Regulated Transcription

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Axon degeneration mechanisms: Commonality amid diversity

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Poly(ADP-ribosyl)ation by PARP-1: `PAR-laying' NAD + into a nuclear signalPreprint

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Regulation of Telomerase by Telomeric Proteins

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Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

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Mitochondrio‐nuclear translocation of AIF in apoptosis and necrosis

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The biochemistry of sirtuins

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Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

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The power to reduce: pyridine nucleotides—small molecules with a multitude of functions

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Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

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Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

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NADPH oxidase

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Mitochondrial α-Ketoglutarate Dehydrogenase Complex Generates Reactive Oxygen Species

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Three Distinct Mechanisms Generate Oxygen Free Radicals in Neurons and Contribute to Cell Death during Anoxia and Reoxygenation

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Role of poly(ADP-ribose) synthetase in inflammation and ischaemia–reperfusion

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Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart

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Tumor Suppressor HIC1 Directly Regulates SIRT1 to Modulate p53-Dependent DNA-Damage Responses

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Poly(ADP-ribose) (PAR) polymer is a death signal

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Ischemic Brain Injury is Mediated by the Activation of Poly(ADP-Ribose)Polymerase

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AIF deficiency compromises oxidative phosphorylation

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Regulation of Corepressor Function by Nuclear NADH

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Novel Competitive Inhibitor of NAD(P)H Oxidase Assembly Attenuates Vascular O2−and Systolic Blood Pressure in Mice

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The thioredoxin system in cancer

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β-Amyloid Peptides Induce Mitochondrial Dysfunction and Oxidative Stress in Astrocytes and Death of Neurons through Activation of NADPH Oxidase

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NAD+-Dependent Modulation of Chromatin Structure and Transcription by Nucleosome Binding Properties of PARP-1

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Targeted disruption of the housekeeping gene encoding glucose 6‐phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress.

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Control of mitochondrial redox balance and cellular defense against oxidative damage by mitochondrial NADP+-dependent isocitrate dehydrogenase

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Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

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Redox signaling in angiogenesis: Role of NADPH oxidase

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Mechanism of Sirtuin Inhibition by Nicotinamide: Altering the NAD+ Cosubstrate Specificity of a Sir2 Enzyme

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NADPH Oxidases in the Kidney

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Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo

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A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice

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PHOSPHORYLATION COUPLED TO OXIDATION OF DIHYDRODIPHOSPHOPYRIDINE NUCLEOTIDE

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Nucleotide receptors

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Poly(ADP-ribose) Polymerase-1-dependent Cardiac Myocyte Cell Death during Heart Failure Is Mediated by NAD+ Depletion and Reduced Sir2α Deacetylase Activity

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Oxidative stress signalling in Alzheimer's disease

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Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

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Peroxynitrite generated by inducible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytes

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