Isoprenoid drugs, biofuels, and Chemicals–Artemisinin, farnesene, and beyond

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

Ro, D.-K., Paradise, E. M., Ouellet, M., Fisher, K. J., Newman, K. L., Ndungu, J. M., Ho, K. A., Eachus, R. A., Ham, T. S., Kirby, J., et al. (2006) · Nature · doi:10.1038/nature04640 · Cited by 2,805 · see citing works

High-level semi-synthetic production of the potent antimalarial artemisinin

Paddon, C. J., Westfall, P. J., Pitera, D. J., Benjamin, K., Fisher, K., McPhee, D., Leavell, M. D., Tai, A., Main, A., Eng, D., et al. (2013) · Nature · doi:10.1038/nature12051 · Cited by 2,060 · see citing works

Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels

Atsumi, S., Hanai, T., & Liao, J. C. (2008) · Nature · doi:10.1038/nature06450 · Cited by 1,945 · see citing works

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

Martin, V. J. J., Pitera, D. J., Withers, S. T., Newman, J. D., & Keasling, J. D. (2003) · Nature Biotechnology · doi:10.1038/nbt833 · Cited by 1,720 · see citing works

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli

Ajikumar, P. K., Xiao, W., Tyo, K. E. J., Wang, Y., Simeon, F., Leonard, E., Mucha, O., Too, H., Pfeifer, B. A., & Stephanopoulos, G. N. (2010) · Science · doi:10.1126/science.1191652 · Cited by 1,681 · see citing works

Programming cells by multiplex genome engineering and accelerated evolution

Wang, H. H., Isaacs, F. J., Carr, P. A., Sun, Z. Z., Xu, G., Forest, C. R., & Church, G. M. (2009) · Nature · doi:10.1038/nature08187 · Cited by 1,529 · see citing works

Synthetic protein scaffolds provide modular control over metabolic flux

Dueber, J. E., Wu, G. C., Malmirchegini, G. R., Moon, T. S., Petzold, C. J., Ullal, A. V., Prather, K. L. J., & Keasling, J. D. (2009) · Nature Biotechnology · doi:10.1038/nbt.1557 · Cited by 1,242 · see citing works

Microbial engineering for the production of advanced biofuels

Peralta‐Yahya, P., Zhang, F., del Cardayré, S. B., & Keasling, J. D. (2012) · Nature · doi:10.1038/nature11478 · Cited by 1,100 · see citing works

Qinghaosu (Artemisinin): The Price of Success

White, N. J. (2008) · Science · doi:10.1126/science.1155165 · Cited by 954 · see citing works

Manufacturing Molecules Through Metabolic Engineering

Keasling, J. D. (2010) · Science · doi:10.1126/science.1193990 · Cited by 829 · see citing works

Molecular Properties of Bacterial Multidrug Transporters

Putman, M., van Veen, H. W., & Konings, W. N. (2000) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.64.4.672-693.2000 · Cited by 792 · see citing works

Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin

Westfall, P. J., Pitera, D. J., Lenihan, J. R., Eng, D., Woolard, F. X., Regentin, R., Horning, T., Tsuruta, H., Melis, D. J., Owens, A. E., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1110740109 · Cited by 726 · see citing works

Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development

Paddon, C. J., & Keasling, J. D. (2014) · Nature Reviews Microbiology · doi:10.1038/nrmicro3240 · Cited by 675 · see citing works

Terpenes

Breitmaier, E. (2006) · Wiley eBooks · doi:10.1002/9783527609949 · Cited by 653 · see citing works

Identification and microbial production of a terpene-based advanced biofuel

Peralta‐Yahya, P., Ouellet, M., Chan, R., Mukhopadhyay, A., Keasling, J. D., & Lee, T. S. (2011) · Nature Communications · doi:10.1038/ncomms1494 · Cited by 638 · see citing works

The Nudix hydrolase superfamily

McLennan, A. G. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-5386-7 · Cited by 636 · see citing works

Dictionary of Terpenoids

Connolly, J. D., & Hill, R. A. (1991) · Springer eBooks · doi:10.1007/978-1-4899-4513-6 · Cited by 633 · see citing works

Anti-inflammatory effects of compounds alpha-humulene and (-)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea

Fernandes, E. S., Passos, G. F., Medeiros, R., da Cunha, F. M., Ferreira, J., Campos, M. M., Pianowski, L. F., & Calixto, J. B. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.04.059 · Cited by 593 · see citing works

Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes

Pfleger, B. F., Pitera, D. J., Smolke, C. D., & Keasling, J. D. (2006) · Nature Biotechnology · doi:10.1038/nbt1226 · Cited by 535 · see citing works

Engineering microbial biofuel tolerance and export using efflux pumps

Dunlop, M. J., Dossani, Z. Y., Szmidt, H. L., Chu, H. C., Lee, T. S., Keasling, J. D., Hadi, M. Z., & Mukhopadhyay, A. (2011) · Molecular Systems Biology · doi:10.1038/msb.2011.21 · Cited by 512 · see citing works

Biosynthesis of Plant Isoprenoids: Perspectives for Microbial Engineering

Kirby, J., & Keasling, J. D. (2009) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.043008.091955 · Cited by 478 · see citing works

Engineering dynamic pathway regulation using stress-response promoters

Dahl, R. H., Zhang, F., Alonso-Gutiérrez, J., Baidoo, E. E. K., Batth, T. S., Redding‐Johanson, A. M., Petzold, C. J., Mukhopadhyay, A., Lee, T. S., Adams, P. D., et al. (2013) · Nature Biotechnology · doi:10.1038/nbt.2689 · Cited by 477 · see citing works

(E)-β-Ocimene and Myrcene Synthase Genes of Floral Scent Biosynthesis in Snapdragon: Function and Expression of Three Terpene Synthase Genes of a New Terpene Synthase Subfamily

Dudareva, N., Martin, D., Kish, C. M., Kolosova, N. P., Gorenstein, N., Fäldt, J., Miller, B., & Bohlmann, J. (2003) · The Plant Cell · doi:10.1105/tpc.011015 · Cited by 467 · see citing works

Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli

Pitera, D. J., Paddon, C. J., Newman, J. D., & Keasling, J. D. (2006) · Metabolic Engineering · doi:10.1016/j.ymben.2006.11.002 · Cited by 440 · see citing works

Meroterpenoids produced by fungi

Geris, R., & Simpson, T. J. (2009) · Natural Product Reports · doi:10.1039/b820413f · Cited by 420 · see citing works

Metabolic engineering of Escherichia coli for limonene and perillyl alcohol production

Alonso-Gutiérrez, J., Chan, R., Batth, T. S., Adams, P. D., Keasling, J. D., Petzold, C. J., & Lee, T. S. (2013) · Metabolic Engineering · doi:10.1016/j.ymben.2013.05.004 · Cited by 415 · see citing works

Functional Characterization of Nine Norway Spruce TPS Genes and Evolution of Gymnosperm Terpene Synthases of the TPS-d Subfamily

Martin, D. M., Fäldt, J., & Bohlmann, J. (2004) · PLANT PHYSIOLOGY · doi:10.1104/pp.104.042028 · Cited by 414 · see citing works

Myrcene as a Natural Base Chemical in Sustainable Chemistry: A Critical Review

Behr, A., & Johnen, L. (2009) · ChemSusChem · doi:10.1002/cssc.200900186 · Cited by 392 · see citing works

Advanced biofuel production in microbes

Peralta‐Yahya, P., & Keasling, J. D. (2010) · Biotechnology Journal · doi:10.1002/biot.200900220 · Cited by 389 · see citing works

Consequences of Membrane Protein Overexpression in Escherichia coli

Wagner, S., Baars, L., Ytterberg, A. J., Klußmeier, A., Wagner, C., Nord, O., Nygren, P., van Wijk, K. J., & Gier, J. D. (2007) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m600431-mcp200 · Cited by 384 · see citing works

Genome shuffling of Lactobacillus for improved acid tolerance

Patnaik, R., Louie, S., Gavrilovic, V., Perry, K., Stemmer, W. P. C., Ryan, C. M., & del Cardayré, S. B. (2002) · Nature Biotechnology · doi:10.1038/nbt0702-707 · Cited by 377 · see citing works

Biofuel alternatives to ethanol: pumping the microbial well

Fortman, J. L., Chhabra, S. R., Mukhopadhyay, A., Chou, H. H., Lee, T. S., Steen, E. J., & Keasling, J. D. (2008) · Trends in biotechnology · doi:10.1016/j.tibtech.2008.03.008 · Cited by 365 · see citing works

Synthesis of three advanced biofuels from ionic liquid-pretreated switchgrass using engineered Escherichia coli

Bokinsky, G., Peralta‐Yahya, P., George, A., Holmes, B. M., Steen, E. J., Dietrich, J. A., Lee, T. S., Tullman‐Ercek, D., Voigt, C. A., Simmons, B. A., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1106958108 · Cited by 365 · see citing works

Engineering Escherichia coli for production of functionalized terpenoids using plant P450s

Chang, M. C. Y., Eachus, R. A., Trieu, W., Ro, D.-K., & Keasling, J. D. (2007) · Nature Chemical Biology · doi:10.1038/nchembio875 · Cited by 364 · see citing works

High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli

Tsuruta, H., Paddon, C. J., Eng, D., Lenihan, J. R., Horning, T., Anthony, L. C., Regentin, R., Keasling, J. D., Renninger, N. S., & Newman, J. D. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004489 · Cited by 364 · see citing works

α-Thujone (the active component of absinthe): γ-Aminobutyric acid type A receptor modulation and metabolic detoxification

Höld, K. M., Sirisoma, N. S., Ikeda, T., Narahashi, T., & Casida, J. E. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.070042397 · Cited by 364 · see citing works

New microbial fuels: a biotech perspective

Rude, M. A., & Schirmer, A. (2009) · Current Opinion in Microbiology · doi:10.1016/j.mib.2009.04.004 · Cited by 338 · see citing works

Studies on the nonmevalonate terpene biosynthetic pathway: Metabolic role of IspH (LytB) protein

Rohdich, F., Hecht, S., Gärtner, K., Adam, P., Krieger, C., Amslinger, S., Arigoni, D., Bacher, A., & Eisenreich, W. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.032658999 · Cited by 338 · see citing works

Stabilized gene duplication enables long-term selection-free heterologous pathway expression

Tyo, K. E. J., Ajikumar, P. K., & Stephanopoulos, G. N. (2009) · Nature Biotechnology · doi:10.1038/nbt.1555 · Cited by 311 · see citing works

Genome-wide Analysis of Substrate Specificities of the Escherichia coli Haloacid Dehalogenase-like Phosphatase Family

Kuznetsova, E., Proudfoot, M., González, C. F., Brown, G., Omelchenko, M. V., Borozan, I., Carmel, L., Wolf, Y. I., Mori, H., Savchenko, A. V., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m605449200 · Cited by 310 · see citing works

Mevalonate and Nonmevalonate Pathways for the Biosynthesis of Isoprene Units

Kuzuyama, T. (2002) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.66.1619 · Cited by 307 · see citing works

Camphor—A Fumigant during the Black Death and a Coveted Fragrant Wood in Ancient Egypt and Babylon—A Review

Chen, W., Vermaak, I., & Viljoen, A. M. (2013) · Molecules · doi:10.3390/molecules18055434 · Cited by 300 · see citing works

Perfume And Flavor Chemicals: (Aroma Chemicals)

Arctander, S. (2000) · Medical Entomology and Zoology · Cited by 299 · see citing works

Metabolic engineering for advanced biofuels production from Escherichia coli

Atsumi, S., & Liao, J. C. (2008) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2008.08.008 · Cited by 297 · see citing works

Aphid Alarm Pheromone: Isolation, Identification, Synthesis

Bowers, W. S., NAULT, L. R., Webb, R. E., & Dutky, S. R. (1972) · Science · doi:10.1126/science.177.4054.1121 · Cited by 296 · see citing works

Engineering microbes for tolerance to next-generation biofuels

Dunlop, M. J. (2011) · Biotechnology for Biofuels · doi:10.1186/1754-6834-4-32 · Cited by 294 · see citing works

Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene

Anthony, J. R., Anthony, L. C., Nowroozi, F., Kwon, G., Newman, J. D., & Keasling, J. D. (2009) · Metabolic Engineering · doi:10.1016/j.ymben.2008.07.007 · Cited by 292 · see citing works

High-Density Renewable Fuels Based on the Selective Dimerization of Pinenes

Harvey, B. G., Wright, M. E., & Quintana, R. L. (2009) · Energy & Fuels · doi:10.1021/ef900799c · Cited by 291 · see citing works

Prostate-Specific Antigen-Activated Thapsigargin Prodrug as Targeted Therapy for Prostate Cancer

Denmeade, S. R., Jakobsen, C. M., Janssen, S., Khan, S. R., Garrett, E. S., Lilja, H. G., Christensen, S. B., & Isaacs, J. T. (2003) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/95.13.990 · Cited by 286 · see citing works

The compatibility of potential bioderived fuels with Jet A-1 aviation kerosene

Chuck, C. J., & Donnelly, J. (2014) · Applied Energy · doi:10.1016/j.apenergy.2013.12.019 · Cited by 281 · see citing works

Biotransformation of limonene by bacteria, fungi, yeasts, and plants

Duetz, W. A., Bouwmeester, H. J., van Beilen, J. B., & Witholt, B. (2003) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-003-1221-y · Cited by 262 · see citing works

High‐level production of amorpha‐4,11‐diene in a two‐phase partitioning bioreactor of metabolically engineered <i>Escherichia coli</i>

Newman, J. D., Marshall, J., Chang, M., Nowroozi, F., Paradise, E., Pitera, D., Newman, K. L., & Keasling, J. D. (2006) · Biotechnology and Bioengineering · doi:10.1002/bit.21017 · Cited by 257 · see citing works

Anti-inflammatory and anti-allergic properties of the essential oil and active compounds from Cordia verbenacea

Passos, G. F., Fernandes, E. S., da Cunha, F. M., Ferreira, J., Pianowski, L. F., Campos, M. M., & Calixto, J. B. (2007) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2006.09.032 · Cited by 250 · see citing works

Engineering Static and Dynamic Control of Synthetic Pathways

Holtz, W. J., & Keasling, J. D. (2010) · Cell · doi:10.1016/j.cell.2009.12.029 · Cited by 245 · see citing works

Reconstitution of a fungal meroterpenoid biosynthesis reveals the involvement of a novel family of terpene cyclases

Itoh, T., Tokunaga, K., Matsuda, Y., Fujii, I., Abe, I., Ebizuka, Y., & Kushiro, T. (2010) · Nature Chemistry · doi:10.1038/nchem.764 · Cited by 229 · see citing works

Microbial Synthesis of Pinene

Sarria, S., Wong, B., Martín, H. G., Keasling, J. D., & Peralta‐Yahya, P. (2014) · ACS Synthetic Biology · doi:10.1021/sb4001382 · Cited by 229 · see citing works

The rice (E)-β-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes

Cheng, A., Xiang, C.-Y., Li, J., Yang, C., Hu, W., Wang, L.-J., Lou, Y., & Chen, X. (2007) · Phytochemistry · doi:10.1016/j.phytochem.2007.04.008 · Cited by 220 · see citing works

Fragrance chemicals in domestic and occupational products

Rastogi, S. C., Heydorn, S., Johansen, J. D., & Basketter, D. A. (2001) · Contact Dermatitis · doi:10.1034/j.1600-0536.2001.450406.x · Cited by 212 · see citing works

Terpenes: Flavors, Fragrances, Pharmaca, Pheromones

Breitmaier, E. (2006) · Cited by 210 · see citing works

Metabolic engineering of Escherichia coli for α-farnesene production

Wang, C., Yoon, S., Jang, H., Chung, Y., Kim, J., Choi, E., & Kim, S.-W. (2011) · Metabolic Engineering · doi:10.1016/j.ymben.2011.08.001 · Cited by 208 · see citing works

The relationship between the chemical composition of three essential oils and their insecticidal activity against Acanthoscelides obtectus (Say)

Papachristos, D., Karamanoli, K., Stamopoulos, D., & Menkissoglu‐Spiroudi, U. (2004) · Pest Management Science · doi:10.1002/ps.798 · Cited by 208 · see citing works

The antibacterial effects of terpene alcohols on Staphylococcus aureus and their mode of action

Inoue, Y. H., Shiraishi, A., Hada, T., Hirose, K., Hamashima, H., & Shimada, J. (2004) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2004.tb09714.x · Cited by 208 · see citing works

Production of the sesquiterpenoid (+)-nootkatone by metabolic engineering of Pichia pastoris

Wriessnegger, T., Augustin, P., Engleder, M., Leitner, E., Müller, M., Kaluzna, I. A., Schürmann, M., Mink, D., Zellnig, G., Schwab, H., et al. (2014) · Metabolic Engineering · doi:10.1016/j.ymben.2014.04.001 · Cited by 203 · see citing works

The alternative respiration pathway in plants: Role and regulation

Wagner, A. M., & Krab, K. (1995) · Physiologia Plantarum · doi:10.1111/j.1399-3054.1995.tb00844.x · Cited by 196 · see citing works

The ‘headache tree’ via umbellulone and TRPA1 activates the trigeminovascular system

Nassini, R., Materazzi, S., Vriens, J., Prenen, J., Benemei, S., Siena, G. D., la Marca, G., Andrè, E., Preti, D., Avonto, C., et al. (2011) · Brain · doi:10.1093/brain/awr272 · Cited by 196 · see citing works

Exploration and Mining of the Bacterial Terpenome

Cane, D. E., & Ikeda, H. (2011) · Accounts of Chemical Research · doi:10.1021/ar200198d · Cited by 194 · see citing works

Identification of Isopentenol Biosynthetic Genes from Bacillus subtilis by a Screening Method Based on Isoprenoid Precursor Toxicity

Withers, S. T., Gottlieb, S. S., Lieu, B., Newman, J. D., & Keasling, J. D. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00861-07 · Cited by 193 · see citing works

Carotenoid-based phenotypic screen of the yeast deletion collection reveals new genes with roles in isoprenoid production

Özaydın, B., Burd, H., Lee, T. S., & Keasling, J. D. (2012) · Metabolic Engineering · doi:10.1016/j.ymben.2012.07.010 · Cited by 182 · see citing works

Efficient conversion of pure and mixed terpene feedstocks to high density fuels

Meylemans, H. A., Quintana, R. L., & Harvey, B. G. (2012) · Fuel · doi:10.1016/j.fuel.2012.01.062 · Cited by 180 · see citing works

Targeted proteomics for metabolic pathway optimization: Application to terpene production

Redding‐Johanson, A. M., Batth, T. S., Chan, R., Krupa, R. A., Szmidt, H. L., Adams, P. D., Keasling, J. D., Lee, T. S., Mukhopadhyay, A., & Petzold, C. J. (2011) · Metabolic Engineering · doi:10.1016/j.ymben.2010.12.005 · Cited by 179 · see citing works

Application of Functional Genomics to Pathway Optimization for Increased Isoprenoid Production

Kizer, L., Pitera, D. J., Pfleger, B. F., & Keasling, J. D. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.02750-07 · Cited by 178 · see citing works

Isolation and bacterial expression of a sesquiterpene synthase cDNA clone from peppermint ( Mentha x piperita , L.) that produces the aphid alarm pheromone ( E )-β-farnesene

Crock, J. E., Wildung, M. R., & Croteau, R. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.24.12833 · Cited by 176 · see citing works

Geraniol, a component of plant essential oils, modulates DNA synthesis and potentiates 5-fluorouracil efficacy on human colon tumor xenografts

Carnésecchi, S., Bras-Gonçalves, R., Bradaïa, A., Zeisel, M. B., Gossé, F., Poupon, M., & Raul, F. (2004) · Cancer Letters · doi:10.1016/j.canlet.2004.06.019 · Cited by 167 · see citing works

Metabolic engineering of Escherichia colifor the biosynthesis of alpha-pinene

Yang, J., Nie, Q., Ren, M., Feng, H., Jiang, X., Zheng, Y., Liu, M., Zhang, H., & Xian, M. (2013) · Biotechnology for Biofuels · doi:10.1186/1754-6834-6-60 · Cited by 163 · see citing works

Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases

Ma, S. M., Garcia, D. E., Redding‐Johanson, A. M., Friedland, G. D., Chan, R., Batth, T. S., Haliburton, J. R., Chivian, D. C., Keasling, J. D., Petzold, C. J., et al. (2011) · Metabolic Engineering · doi:10.1016/j.ymben.2011.07.001 · Cited by 161 · see citing works

Pathway engineering for functional isoprenoids

Misawa, N. (2011) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2011.01.002 · Cited by 161 · see citing works

Monoterpene biosynthesis pathway construction in Escherichia coli

Carter, O. A., Peters, R. J., & Croteau, R. (2003) · Phytochemistry · doi:10.1016/s0031-9422(03)00204-8 · Cited by 157 · see citing works

Reflections on the ‘discovery’ of the antimalarial qinghao

Hsü, E. (2006) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2006.02673.x · Cited by 155 · see citing works

Mono and diterpene production in Escherichia coli

Reiling, K. K., Yoshikuni, Y., Martin, V. J. J., Newman, J. D., Bohlmann, J., & Keasling, J. D. (2004) · Biotechnology and Bioengineering · doi:10.1002/bit.20128 · Cited by 155 · see citing works

The LPP1 and DPP1 Gene Products Account for Most of the Isoprenoid Phosphate Phosphatase Activities inSaccharomyces cerevisiae

Faulkner, A. J., Chen, X., Rush, J. S., Horazdovsky, B. F., Waechter, C. J., Carman, G. M., & Sternweis, P. C. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.21.14831 · Cited by 154 · see citing works

Production of 2-methyl-1-butanol in engineered Escherichia coli

Cann, A. F., & Liao, J. C. (2008) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-008-1631-y · Cited by 147 · see citing works

Cell Cycle Arrest by the Isoprenoids Perillyl Alcohol, Geraniol, and Farnesol Is Mediated by p21Cip1 and p27Kip1 in Human Pancreatic Adenocarcinoma Cells

Wiseman, D. A., Werner, S. R., & Crowell, P. L. (2006) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.111666 · Cited by 140 · see citing works

Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels

Zheng, Y., Liu, Q., Li, L., Qin, W., Yang, J., Zhang, H., Jiang, X., Cheng, T., Liu, W., Xu, X., et al. (2013) · Biotechnology for Biofuels · doi:10.1186/1754-6834-6-57 · Cited by 139 · see citing works

A model for improving microbial biofuel production using a synthetic feedback loop

Dunlop, M. J., Keasling, J. D., & Mukhopadhyay, A. (2010) · Systems and Synthetic Biology · doi:10.1007/s11693-010-9052-5 · Cited by 138 · see citing works

Enhanced Production of Farnesol by Candida albicans Treated with Four Azoles

Hornby, J. M., & Nickerson, K. W. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.6.2305-2307.2004 · Cited by 137 · see citing works

Selected Pseudomonas putida Strains Able To Grow in the Presence of High Butanol Concentrations

Rühl, J., Schmid, A., & Blank, L. M. (2009) · Applied and Environmental Microbiology · doi:10.1128/aem.00225-09 · Cited by 135 · see citing works

Expression, purification and characterization of recombinant (E)-β-farnesene synthase from Artemisia annua

Picaud, S., Brodelius, M., & Brodelius, P. E. (2005) · Phytochemistry · doi:10.1016/j.phytochem.2005.03.027 · Cited by 133 · see citing works

Engineering Complex Phenotypes in Industrial Strains

Patnaik, R. (2007) · Biotechnology Progress · doi:10.1021/bp0701214 · Cited by 124 · see citing works

Microbial production of sabinene—a new terpene-based precursor of advanced biofuel

Zhang, H., Liu, Q., Cao, Y., Feng, X., Zheng, Y., Zou, H., Liu, H., Yang, J., & Xian, M. (2014) · Microbial Cell Factories · doi:10.1186/1475-2859-13-20 · Cited by 124 · see citing works

Microbial production of isoprenoids

Chandran, S. S., Kealey, J. T., & Reeves, C. D. (2011) · Process Biochemistry · doi:10.1016/j.procbio.2011.05.012 · Cited by 121 · see citing works

Hydrogenated monoterpenes as diesel fuel additives

Tracy, N. I., Chen, D., Crunkleton, D. W., & Price, G. L. (2009) · Fuel · doi:10.1016/j.fuel.2009.02.002 · Cited by 118 · see citing works

Engineering microbial cell factories for biosynthesis of isoprenoid molecules: beyond lycopene

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