CoChat
Sign Up
Cited by 73Evolution and Genetic DynamicsViral Infections and Immunology ResearchVirology and Viral Diseases

Molecular Mechanisms of Poliovirus Variation and Evolution

Agol, V. I.·2006·Current Topics in Microbiology and Immunology
DOI 10.1007/3-540-26397-7_8
Open this paper in CoChat — free account

Abstract

Replication of poliovirus RNA is accomplished by the error-prone viral RNA-dependent RNA polymerase and hence is accompanied by numerous mutations. In addition, genetic errors may be introduced by nonreplicative mechanisms. Resulting variability is manifested by point mutations and genomic rearrangements (e.g., deletions, insertions and recombination). After description of basic mechanisms underlying this variability, the review focuses on regularities of poliovirus evolution (mutation fixation) in tissue cultures, human organisms and populations.

Integrity signals

Registry

Crossref · 10.1007/3-540-26397-7_8

Cites

20 of 20 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Due to the variability and rapid evolution of enteroviruses, polio eradication may be more difficult than initially expected.

    “Due to the variability and rapid evolution of enteroviruses, polio eradication may be more difficult than initially expected [8].”

    From The Fight against Poliovirus Is Not Over (2023) · cites this paper as [8]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Agol, V. I.
Affiliations
Lomonosov Moscow State University (RU)
Corresponding author
Agol, V. I.
Venue
Current Topics in Microbiology and Immunology
Publisher
Springer Berlin Heidelberg
Published
2006
Volume
299
Pages
211-259
ISSN
0070-217X (ISSN-L)
DOI
10.1007/3-540-26397-7_8
OpenAlex
W56393926
Cited by
73
References
20
Citations by year
2026: 1 · 2025: 2 · 2023: 3 · 2022: 2 · 2019: 1 · 2018: 3 · 2017: 4 · 2016: 2 · 2015: 2 · 2014: 6 · 2013: 6 · 2012: 3
FWCI
17.47
Type
book chapter
Language
en
Open access
closed
Licence
Locations
  • Current topics in microbiology and immunology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
  • Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
Keywords
poliovirus, viral evolution, genetic variation, RNA-dependent RNA polymerase, error-prone replication, point mutations, genome rearrangement, recombination, indels, mutation fixation, tissue culture, natural populations
MeSH terms
Animals, Humans, Recombination, Genetic, Selection, Genetic, Genetic Variation, Virus Replication, Gene Rearrangement, Genome, Viral, Point Mutation, Poliovirus, Evolution, Molecular

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review