Long-term circulation of vaccine-derived poliovirus that causes paralytic disease

Cherkasova, Elena A.; Korotkova, Ekaterina A.; Yakovenko, Maria L.; Ivanova, Olga E.; Eremeeva, Tatyana P.; Chumakov, Konstantin M.; Agol, Vadim I.

doi:10.1128/jvi.76.13.6791-6799.2002

Cited by 103Viral Infections and Immunology ResearchEvolution and Genetic DynamicsVirology and Viral Diseases

Long-term circulation of vaccine-derived poliovirus that causes paralytic disease

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Cherkasova, Elena A., Korotkova, Ekaterina A., Yakovenko, Maria L., Ivanova, Olga E., Eremeeva, Tatyana P., Chumakov, Konstantin M., Agol, Vadim I.·2002·Journal of Virology

DOI 10.1128/jvi.76.13.6791-6799.2002PMC PMC136293

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Abstract

Successful implementation of the global poliomyelitis eradication program raises the problem of vaccination against poliomyelitis in the posteradication era. One of the options under consideration envisions completely stopping worldwide the use of the Sabin vaccine. This strategy is based on the assumption that the natural circulation of attenuated strains and their derivatives is strictly limited. Here, we report the characterization of a highly evolved derivative of the Sabin vaccine strain isolated in a case of paralytic poliomyelitis from a 7-month-old immunocompetent baby in an apparently adequately immunized population. Analysis of the genome of this isolate showed that it is a double (type 1-type 2-type 1) vaccine-derived recombinant. The number of mutations accumulated in both the type 1-derived and type 2-derived portions of the recombinant genome suggests that both had diverged from their vaccine predecessors ∼2 years before the onset of the illness. This fact, along with other recent observations, points to the possibility of long-term circulation of Sabin vaccine strain derivatives associated with an increase in their neurovirulence. Comparison of genomic sequences of this and other evolved vaccine-derived isolates reveals some general features of natural poliovirus evolution. They include a very high preponderance and nonrandom distribution of synonymous substitutions, conservation of secondary structures of important cis -acting elements of the genome, and an apparently adaptive character of most of the amino acid mutations, with only a few of them occurring in the antigenic determinants. Another interesting feature is a frequent occurrence of tripartite intertypic recombinants with either type 1 or type 3 homotypic genomic ends.

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Recombination is most often detected in Sabin 2 and Sabin 3 derived isolates and rarely in Sabin 1.
“Recombination is most often detected in Sabin 2 and Sabin 3 derived isolates and rarely in Sabin 1 [50–52,55,56].”
From Recombination between Poliovirus and Coxsackie A Viruses of Species C: A Model of Viral Genetic Plasticity and Emergence (2011) · cites this paper as [52]
The underlying cause of vaccine-associated paralytic poliomyelitis (VAPP) is the genetic instability of oral polio vaccine (OPV) strains, as key substitutions conferring the attenuated phenotype of Sabin strains have been frequently found to be reverted in isolates from VAPP cases.
“The underlying cause of VAPP is the genetic instability of OPV strains, as key substitutions conferring the attenuated phenotype of Sabin strains have been frequently found to be reverted in isolates from VAPP cases [52].”
From Recombination between Poliovirus and Coxsackie A Viruses of Species C: A Model of Viral Genetic Plasticity and Emergence (2011) · cites this paper as [52]
In Russia in 1999, an immunocompetent seven-month-old orphanage child contracted VAPP associated with a type 1 VDPV.
“In Russia in 1999, an immunocompetent seven-month-old orphanage child contracted VAPP associated with a type 1 VDPV (26).”
From VACCINE-DERIVED POLIOVIRUSES AND THE ENDGAME STRATEGY FOR GLOBAL POLIO ERADICATION (2005) · cites this paper as [26]
The two 1999 aVDPVs from Russia were isolated from different children living in the same orphanage, and although the isolates were of different serotypes, they shared some vaccine/vaccine recombinant noncapsid sequences.
“The two 1999 aVDPVs from Russia were isolated from different children living in the same orphanage, and although the isolates were of different serotypes, they shared some vaccine/vaccine recombinant noncapsid sequences”
From VACCINE-DERIVED POLIOVIRUSES AND THE ENDGAME STRATEGY FOR GLOBAL POLIO ERADICATION (2005) · cites this paper as [26]

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
Thompson, J. D., Higgins, D. G., & Gibson, T. J. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.22.4673 · Cited by 64,617 · see citing works
SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling
Guex, N., & Peitsch, M. (1997) · Electrophoresis · doi:10.1002/elps.1150181505 · Cited by 11,589 · see citing works
RASMOL: biomolecular graphics for all
Sayle, R. A. (1995) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)89080-5 · Cited by 2,587 · see citing works
Three-Dimensional Structure of Poliovirus at 2.9 Å Resolution
Hogle, J. M., Chow, M., & Filman, D. J. (1985) · Science · doi:10.1126/science.2994218 · Cited by 1,262 · see citing works
A new method for estimating synonymous and nonsynonymous rates of nucleotide substitution considering the relative likelihood of nucleotide and codon changes.
Li, W., Wu, C., & Luo, C. C. (1985) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040343 · Cited by 1,053 · see citing works
Origin and Evolution of Viruses
Holland, J. J., & Domingo, E. (1998) · Virus Genes · doi:10.1023/a:1007989407305 · Cited by 524 · see citing works
Fitness of RNA virus decreased by Muller’s ratchet
Chao, L. (1990) · Nature · doi:10.1038/348454a0 · Cited by 488 · see citing works
Complete nucleotide sequences of all three poliovirus serotype genomes
Toyoda, H., Kohara, M., Kataoka, Y., Suganuma, T., Omata, T., Imura, N., & Nomoto, A. (1984) · Journal of Molecular Biology · doi:10.1016/0022-2836(84)90084-6 · Cited by 418 · see citing works
WORLD HEALTH ASSEMBLY
Turner, J. (1989) · The Lancet · doi:10.1016/s0140-6736(89)92377-5 · Cited by 388 · see citing works
New model for the secondary structure of the 5′ non-coding RNA of poliovirus is supported by biochemical and genetic data that also show that RNA secondary structure is important in neurovirulence
Skinner, M. A., Racaniello, V. R., Dunn, G., Cooper, J., Minor, P. D., & Almond, J. W. (1989) · Journal of Molecular Biology · doi:10.1016/0022-2836(89)90261-1 · Cited by 297 · see citing works
Identification of an RNA Hairpin in Poliovirus RNA That Serves as the Primary Template in the In Vitro Uridylylation of VPg
Paul, A. V., Rieder, E. A., Kim, D. W., BOOM, J. H. V., & Wimmer, E. (2000) · Journal of Virology · doi:10.1128/jvi.74.22.10359-10370.2000 · Cited by 289 · see citing works
Molecular Aspects of Picornavirus Infection and Detection
Semler, B. L., & Ehrenfeld, E. (1989) · Medical Entomology and Zoology · Cited by 259 · see citing works
Conserved structural domains in the 5′-untranslated region of picornaviral genomes: An analysis of the segment controlling translation and neurovirulence
Pilipenko, E. V., Blinov, V. M., Romanova, L. I., Sinyakov, A. N., Maslova, S. V., & Agol, V. I. (1989) · Virology · doi:10.1016/0042-6822(89)90259-6 · Cited by 259 · see citing works
Self-citation
Identification of a cis -Acting Replication Element within the Poliovirus Coding Region
Goodfellow, I., Chaudhry, Y., Richardson, A., Meredith, J. M., Almond, J. W., Barclay, W., & Evans, D. J. (2000) · Journal of Virology · doi:10.1128/jvi.74.10.4590-4600.2000 · Cited by 254 · see citing works
Transmissibility and Persistence of Oral Polio Vaccine Viruses: Implications for the Global Poliomyelitis Eradication Initiative
Fine, P. E. M., & Carneiro, I. A. M. (1999) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009924 · Cited by 247 · see citing works
Interaction of the poliovirus receptor with poliovirus
He, Y., Bowman, V. D., Mueller, S., Bator, C. M., Bella, J., Peng, X., Baker, T. S., Wimmer, E., Kuhn, R. J., & Rossmann, M. G. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.1.79 · Cited by 243 · see citing works
Molecular Tectonic Model of Virus Structural Transitions: the Putative Cell Entry States of Poliovirus
Belnap, D. M., Filman, D. J., Trus, B. L., Cheng, N., Booy, F. P., Conway, J. F., Curry, S., Hiremath, C. N., Tsang, S. K., Steven, A. C., et al. (2000) · Journal of Virology · doi:10.1128/jvi.74.3.1342-1354.2000 · Cited by 236 · see citing works
Interactions of Viral Protein 3CD and Poly(rC) Binding Protein with the 5′ Untranslated Region of the Poliovirus Genome
Gamarnik, A. V., & Andino, R. (2000) · Journal of Virology · doi:10.1128/jvi.74.5.2219-2226.2000 · Cited by 235 · see citing works
Determinants in the 5' noncoding region of poliovirus Sabin 1 RNA that influence the attenuation phenotype
Kawamura, N., Kohara, M., Abe, S., Komatsu, T., Tago, K., Arita, M., & Nomoto, A. (1989) · Journal of Virology · doi:10.1128/jvi.63.3.1302-1309.1989 · Cited by 232 · see citing works
Recent changes to RasMol, recombining the variants
Bernstein, H. J., & Bernstein, H. J. (2000) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)01606-6 · Cited by 230 · see citing works
Three-dimensional structure of poliovirus serotype 1 neutralizing determinants
Page, G. S., Mosser, A. G., Hogle, J. M., Filman, D. J., Rueckert, R. R., & Chow, M. (1988) · Journal of Virology · doi:10.1128/jvi.62.5.1781-1794.1988 · Cited by 222 · see citing works
Poly(rC) binding protein 2 binds to stem-loop IV of the poliovirus RNA 5' noncoding region: identification by automated liquid chromatography-tandem mass spectrometry.
Blyn, L., Swiderek, K., Richards, O. C., Stahl, D. C., Semler, B., & Ehrenfeld, E. (1996) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.93.20.11115 · Cited by 219 · see citing works
The molecular biology of poliovaccines
Minor, P. D. (1992) · Journal of General Virology · doi:10.1099/0022-1317-73-12-3065 · Cited by 217 · see citing works
Prolonged replication of a type 1 vaccine-derived poliovirus in an immunodeficient patient
Kew, O. M., Sutter, R. W., Nottay, B. K., McDonough, M. J., Prevots, D. R., Quick, L., & Pallansch, M. A. (1998) · Journal of Clinical Microbiology · doi:10.1128/jcm.36.10.2893-2899.1998 · Cited by 213 · see citing works
Antigenic and Molecular Evolution of the Vaccine Strain of Type 3 Poliovirus during the Period of Excretion by a Primary Vaccinee
Minor, P. D., John, A., Ferguson, M. A. J., & Icenogle, J. P. (1986) · Journal of General Virology · doi:10.1099/0022-1317-67-4-693 · Cited by 203 · see citing works
Genetic analysis of the attenuation phenotype of poliovirus type 1
Omata, T., Kohara, M., Kuge, S., Komatsu, T., Abe, S., Semler, B. L., Kameda, A., Itoh, H., Arita, M., & Wimmer, E. (1986) · Journal of Virology · doi:10.1128/jvi.58.2.348-358.1986 · Cited by 190 · see citing works
Genetic and Biochemical Studies of Poliovirus cis -Acting Replication Element cre in Relation to VPg Uridylylation
Rieder, E. A., Paul, A. V., Kim, D. W., BOOM, J. H. V., & Wimmer, E. (2000) · Journal of Virology · doi:10.1128/jvi.74.22.10371-10380.2000 · Cited by 167 · see citing works
Differences in replication of attenuated and neurovirulent polioviruses in human neuroblastoma cell line SH-SY5Y
Monica, N. L., & Racaniello, V. R. (1989) · Journal of Virology · doi:10.1128/jvi.63.5.2357-2360.1989 · Cited by 165 · see citing works
The natural genomic variability of poliovirus analyzed by a restriction fragment length polymorphism assay
Balanant, J., Guillot, S., Candrea, A., Delpeyroux, F., & Crainic, R. (1991) · Virology · doi:10.1016/0042-6822(91)90434-d · Cited by 160 · see citing works
Evolution of the Sabin Strain of Type 3 Poliovirus in an Immunodeficient Patient during the Entire 637-Day Period of Virus Excretion
Martín, J., Dunn, G., Hull, R., Patel, V., & Minor, P. D. (2000) · Journal of Virology · doi:10.1128/jvi.74.7.3001-3010.2000 · Cited by 160 · see citing works
Determinants of Membrane Association for Poliovirus Protein 3AB
Towner, J. S., Ho, T. V., & Semler, B. L. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.43.26810 · Cited by 156 · see citing works
The Genomes of attenuated and virulent poliovirus strains differ in their in vitro translation efficiencies
Svitkin, Y. V., Maslova, S. V., & Agol, V. I. (1985) · Virology · doi:10.1016/0042-6822(85)90127-8 · Cited by 148 · see citing works
Self-citation
Polioviruses with Natural Recombinant Genomes Isolated from Vaccine-Associated Paralytic Poliomyelitis
Furlone, M., Guillot, S., Otelea, D., Balanant, J., Candrea, A., & Crainic, R. (1993) · Virology · doi:10.1006/viro.1993.1468 · Cited by 148 · cited 1× · see citing works
“Poliovirus isolates from VAPP patients are very often represented by intertypic recombinants (23, 24 , 29, 43).”
Background
Detection and identification of vaccine-related polioviruses by the polymerase chain reaction
Yang, C.-F., De, L., Holloway, B. P., Pallansch, M. A., & Kew, O. M. (1991) · Virus Research · doi:10.1016/0168-1702(91)90107-7 · Cited by 145 · see citing works
Determinants of attenuation and temperature sensitivity in the type 1 poliovirus Sabin vaccine
Bouchard, M. J., Lam, D. H., & Racaniello, V. R. (1995) · Journal of Virology · doi:10.1128/jvi.69.8.4972-4978.1995 · Cited by 140 · see citing works
Evolution of Circulating Wild Poliovirus and of Vaccine-Derived Poliovirus in an Immunodeficient Patient: a Unifying Model
Gavrilin, G. V., Cherkasova, E. A., Lipskaya, G. Y., Kew, O. M., & Agol, V. I. (2000) · Journal of Virology · doi:10.1128/jvi.74.16.7381-7390.2000 · Cited by 138 · see citing works
Self-citation
Genomic Features of Intertypic Recombinant Sabin Poliovirus Strains Excreted by Primary Vaccinees
Cuervo, N. S., Guillot, S., Romanenkova, N., Combiescu, M., Aubert-Combiescu, A., Seghier, M., Caro, V., Crainic, R., & Delpeyroux, F. (2001) · Journal of Virology · doi:10.1128/jvi.75.13.5740-5751.2001 · Cited by 136 · see citing works
Evolution of Poliovirus Type I during 5.5 Years of Prolonged Enteral Replication in an Immunodeficient Patient
Bellmunt, A., May, G., Zell, R., Pring-Åkerblom, P., Verhagen, W., & Heim, A. (1999) · Virology · doi:10.1006/viro.1999.0003 · Cited by 128 · cited 8× · see citing works
“In principle, some synonymous substitutions may well affect biological properties of a virus (for a more detailed discussion of this point, see reference 26), and the occurrence of such silent mutations as C880U, U1141C, G1351A, U1798C, C2092U, and U2293C in another Sabin 1 derivative (5) may hint at their possible bi…”
BackgroundResultInfluential
Point mutations modify the response of poliovirus RNA to a translation initiation factor: A comparison of neurovirulent and attenuated strains
Svitkin, Y. V., Pestova, T. V., Maslova, S. V., & Agol, V. I. (1988) · Virology · doi:10.1016/0042-6822(88)90510-7 · Cited by 126 · see citing works
Self-citation
Comparative study of five methods for intratypic differentiation of polioviruses
van der Avoort, H. G., Hull, B. P., Hovi, T., Pallansch, M. A., Kew, O. M., Crainic, R., Wood, D. J., Mulders, M. N., & van Loon, A. M. (1995) · Journal of Clinical Microbiology · doi:10.1128/jcm.33.10.2562-2566.1995 · Cited by 122 · see citing works
Intertypic genomic rearrangements of poliovirus strains in vaccinees
Cammack, N. C., Phillips, A., Dunn, G., Patel, V., & Minor, P. D. (1988) · Virology · doi:10.1016/0042-6822(88)90113-4 · Cited by 111 · see citing works
Intertypic genomic rearrangements of poliovirus strains in vaccinees
CAMMACK, N., PHILLIPS, A., DUNN, G., PATEL, V, & MINOR, P. (1988) · Virology · doi:10.1016/s0042-6822(88)90113-4 · Cited by 111 · see citing works
High diversity of poliovirus strains isolated from the central nervous system from patients with vaccine-associated paralytic poliomyelitis
Georgescu, M., Delpeyroux, F., Tardy-Panit, M., Balanant, J., Combiescu, M., Aubert-Combiescu, A., Guillot, S., & Crainic, R. (1994) · Journal of Virology · doi:10.1128/jvi.68.12.8089-8101.1994 · Cited by 109 · see citing works
Molecular and Antigenic Characterization of a Highly Evolved Derivative of the Type 2 Oral Poliovaccine Strain Isolated from Sewage in Israel
Shulman, L. M., Manor, Y., Handsher, R., Delpeyroux, F., McDonough, M., Halmut, T., Silberstein, I., Alfandari, J., Quay, J., Fisher, T., et al. (2000) · Journal of Clinical Microbiology · doi:10.1128/jcm.38.10.3729-3734.2000 · Cited by 109 · see citing works
Stopping poliovirus vaccination after eradication: issues and challenges.
Wood, D. J., Sutter, R. W., & Dowdle, W. R. (2000) · Europe PMC (PubMed Central) · doi:10.1590/s0042-96862000000300010 · Cited by 107 · see citing works
Mapping of mutations associated with neurovirulence in monkeys infected with Sabin 1 poliovirus revertants selected at high temperature
Christodoulou, C., Colbère-Garapin, F., Macadam, A. J., Taffs, L. F., Marsden, S. A., Minor, P. D., & Horaud, F. (1990) · Journal of Virology · doi:10.1128/jvi.64.10.4922-4929.1990 · Cited by 106 · see citing works
Soluble receptor‐resistant poliovirus mutants identify surface and internal capsid residues that control interaction with the cell receptor.
Colston, E., & Racaniello, V. R. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06930.x · Cited by 104 · see citing works
Frequent isolation of intertypic poliovirus recombinants with serotype 2 specificity from vaccine‐associated polio cases
Lipskaya, G. Y., Muzychenko, A. R., Kutitova, O. K., Maslova, S. V., Equestre, M., Drozdov, S. G., Bercoff, R. P., & Agol, V. I. (1991) · Journal of Medical Virology · doi:10.1002/jmv.1890350415 · Cited by 97 · see citing works
Self-citation
Evolution of the Sabin type 1 poliovirus in humans: characterization of strains isolated from patients with vaccine-associated paralytic poliomyelitis
Georgescu, M. M., Balanant, J., Macadam, A., Otelea, D., Combiescu, M., Combiescu, A. A., Crainic, R., & Delpeyroux, F. (1997) · Journal of Virology · doi:10.1128/jvi.71.10.7758-7768.1997 · Cited by 83 · see citing works
Studies on the recombination between RNA genomes of poliovirus: The primary structure and nonrandom distribution of crossover regions in the genomes of intertypic poliovirus recombinants
Tolskaya, E. A., Romanova, L. I., Blinov, V. M., Viktorova, E. G., Sinyakov, A. N., Kolesnikova, M. S., & Agol, V. I. (1987) · Virology · doi:10.1016/0042-6822(87)90170-x · Cited by 81 · see citing works
Self-citation
Poliovirus variants selected on mutant receptor-expressing cells identify capsid residues that expand receptor recognition
Colston, E. M., & Racaniello, V. R. (1995) · Journal of Virology · doi:10.1128/jvi.69.8.4823-4829.1995 · Cited by 75 · see citing works
The Polio Eradication Effort: Should Vaccine Eradication Be Next?
Dove, A. W., & Racaniello, V. R. (1997) · Science · doi:10.1126/science.277.5327.779 · Cited by 71 · see citing works
Recombination and Other Genomic Rearrangements in Picornaviruses
Agol, V. I. (1997) · Seminars in Virology · doi:10.1006/smvy.1997.0112 · Cited by 66 · see citing works
Self-citation
A mutation in the RNA polymerase of poliovirus type 1 contributes to attenuation in mice
Tardy-Panit, M., Blondel, B., Martin, A., Tekaia, F., Horaud, F., & Delpeyroux, F. (1993) · Journal of Virology · doi:10.1128/jvi.67.8.4630-4638.1993 · Cited by 64 · see citing works
Viral Quasispecies and Fitness Variations
Domingo, E., Escarmı́s, C., Menéndez‐Arias, L., & Holland, J. J. (1999) · Elsevier eBooks · doi:10.1016/b978-012220360-2/50008-8 · Cited by 63 · see citing works
A mutation present in the amino terminus of Sabin 3 poliovirus VP1 protein is attenuating
Tatem, J. M., Weeks-Levy, C., Georgiu, A. F., Dimichele, S. J., Gorgacz, E. J., Racaniello, V. R., Cano, F. R., & Mento, S. J. (1992) · Journal of Virology · doi:10.1128/jvi.66.5.3194-3197.1992 · Cited by 62 · see citing works
Disease eradication as a public health strategy: a case study of poliomyelitis eradication.
Aylward, R. B., Hull, H. F., Cochi, S. L., Sutter, R. W., Olivé, J. M., & Melgaard, B. (2000) · Europe PMC (PubMed Central) · Cited by 60 · see citing works
Coupled mutations in the 5'-untranslated region of the Sabin poliovirus strains during in vivo passages: structural and functional implications
Muzychenko, A. R., Lipskaya, G. Y., Maslova, S. V., Svitkin, Y. V., Pilipenko, E. V., Nottay, B. K., Kew, O. M., & Agol, V. I. (1991) · Virus Research · doi:10.1016/0168-1702(91)90002-d · Cited by 45 · see citing works
Self-citation
Alteration in oligonucleotide fingerprint patterns of the viral genome in poliovirus type 2 isolated from paralytic patients
Yoneyama, T., Hagiwara, A., Hara, M., & Shimojo, H. (1982) · Infection and Immunity · doi:10.1128/iai.37.1.46-53.1982 · Cited by 45 · see citing works
Genetic basis of the neurovirulence of type 1 polioviruses isolated from vaccine-associated paralytic patients
Li, J., Zhang, L. B., Yoneyama, T., Yoshida, H., Shimizu, H., Yoshii, K., Hara, M., Nomura, T., Yoshikura, H., Miyamura, T., et al. (1996) · Archives of Virology · doi:10.1007/bf01718608 · Cited by 40 · see citing works
A Sabin vaccine-derived field isolate of poliovirus type 1 displaying aberrant phenotypic and genetic features, including a deletion in antigenic site 1.
Mulders, M. N., Reimerink, J. H. J., Stenvik, M., Alàeddínoğlu, I., van der Avoort, H. G. A. M., Hovi, T., & Koopmans, M. (1999) · Journal of General Virology · doi:10.1099/0022-1317-80-4-907 · Cited by 38 · see citing works
Assessment of Poliovirus Eradication in Japan: Genomic Analysis of Polioviruses Isolated from River Water and Sewage in Toyama Prefecture
Matsuura, K., Ishikura, M., Yoshida, H., Nakayama, T., Hasegawa, S., Ando, S., Horie, H., Miyamura, T., & Kitamura, T. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.11.5087-5091.2000 · Cited by 37 · see citing works
Circulation of a Type 2 Vaccine-Derived Poliovirus--Egypt, 1982-1993
(2001) · JAMA · doi:10.1001/jama.285.9.1148 · Cited by 34 · see citing works
Genetic Stability and Mutant Selection in Sabin 2 Strain of Oral Poliovirus Vaccine Grown under Different Cell Culture Conditions
Taffs, R. E., Chumakov, K. M., Rezapkin, G. V., Lu, Z., Douthitt, M., Dragunsky, E. M., & Levenbook, I. S. (1995) · Virology · doi:10.1006/viro.1995.1268 · Cited by 33 · see citing works
Self-citation
Genomic modifications in naturally occurring neurovirulent revertants of Sabin 1 polioviruses.
Oţelea, D., Guillot, S., Furione, M., Aubert-Combiescu, A., Balanant, J., Candrea, A., & Crainic, R. (1993) · PubMed · Cited by 33 · see citing works
Microevolution of Type 3 Sabin Strain of Poliovirus in Cell Cultures and Its Implications for Oral Poliovirus Vaccine Quality Control
Rezapkin, G. V., Norwood, L. P., Taffs, R. E., Dragunsky, E. M., Levenbook, I. S., & Chumakov, K. M. (1995) · Virology · doi:10.1006/viro.1995.1420 · Cited by 32 · see citing works
Self-citation
Ending Polio Immunization
Hull, H. F., & Aylward, R. B. (1997) · Science · doi:10.1126/science.277.5327.780 · Cited by 31 · see citing works
Vaccine-associated cases of poliomyelitis over a 30 year period in East Germany
Driesel, G., Diedrich, S., Künkel, U., & Schreier, E. (1995) · European Journal of Epidemiology · doi:10.1007/bf01720298 · Cited by 25 · see citing works
Acute Flaccid Paralysis Associated With Circulating Vaccine-Derived Poliovirus—Philippines, 2001
(2002) · JAMA · doi:10.1001/jama.287.3.311-jwr0116-2-1 · Cited by 25 · see citing works
Update: Outbreak of Poliomyelitis—Dominican Republic and Haiti, 2000-2001
(2001) · JAMA · doi:10.1001/jama.286.22.2802 · Cited by 24 · see citing works
Evidence for a complex structure of neutralization antigenic site I of poliovirus type 1 Mahoney
Wiegers, K. J., Uhlig, H., & Dernick, R. (1988) · Journal of Virology · doi:10.1128/jvi.62.5.1845-1848.1988 · Cited by 21 · see citing works
Random selection: a model for poliovirus infection of the central nervous system.
Georgescu, M. M., Ozden, S., Crainic, R., & Balanant, J. (1997) · Journal of General Virology · doi:10.1099/0022-1317-78-8-1819 · Cited by 21 · see citing works
Type 2 poliovirus recombinants isolated from vaccine-associated cases and from healthy contacts in Brazil.
Friedrich, F., Ef, D.-S., & Hg, S. (1996) · PubMed · Cited by 21 · see citing works
Genetic Diversity and Rapid Evolution of Poliovirus in Human Hosts
Kinnunen, L., Pöyry, T. A. A., & Hovi, T. (1992) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-77011-1_4 · Cited by 20 · see citing works
It is too early to stop polio vaccination.
Racaniello, V. R. (2000) · PubMed · Cited by 16 · see citing works
Some problems of molecular biology of poliovirus infection relevant to pathogenesis, viral spread and evolution.
Agol, V. I., Belov, G. A., Cherkasova, E. A., Gavrilin, G. V., Kolesnikova, M. S., Romanova, L. I., & Tolskaya, E. A. (2001) · PubMed · Cited by 6 · see citing works
Self-citation
INTRODUCTION
Mayo, M. A. (1997) · Seminars in Virology · doi:10.1006/smvy.1997.0100 · Cited by 6 · see citing works

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VACCINE-DERIVED POLIOVIRUSES AND THE ENDGAME STRATEGY FOR GLOBAL POLIO ERADICATION
Kew, O. M., Sutter, R. W., de Gourville, E. M., Dowdle, W. R., & Pallansch, M. A. (2005) · Annual Review of Microbiology · doi:10.1146/annurev.micro.58.030603.123625 · Cited by 703 · see citing works
Pathogen recognition and development of particulate vaccines: Does size matter?
Xiang, S. D., Scholzen, A., Minigo, G., David, C. T., Apostolopoulos, V., Mottram, P. L., & Plebanski, M. (2006) · Methods · doi:10.1016/j.ymeth.2006.05.016 · Cited by 602 · see citing works
Immunity in response to particulate antigen-delivery systems
Storni, T., Kündig, T. M., Senti, G., & Johansen, P. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2004.09.008 · Cited by 315 · see citing works
Evidence for Frequent Recombination within SpeciesHuman Enterovirus BBased on Complete Genomic Sequences of All Thirty-Seven Serotypes
Oberste, M. S., Maher, K., & Pallansch, M. A. (2003) · Journal of Virology · doi:10.1128/jvi.78.2.855-867.2004 · Cited by 258 · see citing works
Circulating vaccine-derived polioviruses: current state of knowledge.
Kew, O. M., Wright, P. F., Agol, V. I., Delpeyroux, F., Shimizu, H., Nathanson, N., & Pallansch, M. A. (2004) · Europe PMC (PubMed Central) · doi:10.1590/s0042-96862004000100006 · Cited by 256 · see citing works
Self-citation
Orchestrating immune responses: How size, shape and rigidity affect the immunogenicity of particulate vaccines
Benne, N., van Duijn, J., Kuiper, J., Jiskoot, W., & Slütter, B. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.05.033 · Cited by 247 · see citing works
Risks of Paralytic Disease Due to Wild or Vaccine‐Derived Poliovirus After Eradication
Tebbens, R. J. D., Pallansch, M. A., Kew, O. M., Cáceres, V. M., Jafari, H. S., Cochi, S. L., Sutter, R. W., Aylward, R. B., & Thompson, K. M. (2006) · Risk Analysis · doi:10.1111/j.1539-6924.2006.00827.x · Cited by 174 · see citing works
Circulation of type 1 vaccine-derived poliovirus in the philippines in 2001
Shimizu, H., Thorley, B., Paladin, F. J., Brussen, K. A., Stambos, V., Yuen, L., Utama, A., Tano, Y., Arita, M., Yoshida, H., et al. (2004) · Journal of Virology · doi:10.1128/jvi.78.24.13512-13521.2004 · Cited by 146 · see citing works
Polio eradication: the OPV paradox
Dowdle, W. R., De Gourville, E., Kew, O. M., Pallansch, M. A., & Wood, D. J. (2003) · Reviews in Medical Virology · doi:10.1002/rmv.401 · Cited by 144 · see citing works
RNA Recombination Plays a Major Role in Genomic Change during Circulation of Coxsackie B Viruses
Oberste, M. S., Peñaranda, S., & Pallansch, M. A. (2004) · Journal of Virology · doi:10.1128/jvi.78.6.2948-2955.2004 · Cited by 137 · see citing works
Recombination between Poliovirus and Coxsackie A Viruses of Species C: A Model of Viral Genetic Plasticity and Emergence
Combelas, N., Holmblat, B., Joffret, M.-L., Colbère-Garapin, F., & Delpeyroux, F. (2011) · Viruses · doi:10.3390/v3081460 · Cited by 135 · see citing works
Aseptic meningitis: Case definition and guidelines for collection, analysis and presentation of immunization safety data
Tapiainen, T., Prevots, R., Izurieta, H. S., Abramson, J. S., Bilynsky, R., Bonhoeffer, J., Bonnet, M.-C., Galama, J. M. D., Gillard, P. H., Griot, M., et al. (2007) · Vaccine · doi:10.1016/j.vaccine.2007.04.058 · Cited by 111 · see citing works
Vaccines, Vaccination, and Vaccinology
Plotkin, S. A. (2003) · The Journal of Infectious Diseases · doi:10.1086/374419 · Cited by 109 · see citing works
Characterization of a Highly Evolved Vaccine-Derived Poliovirus Type 3 Isolated from Sewage in Estonia
Blomqvist, S., Savolainen, C., Laine, P., Hirttiö, P., Lamminsalo, E., Penttilä, E., Jöks, S., Roivainen, M., & Hovi, T. (2004) · Journal of Virology · doi:10.1128/jvi.78.9.4876-4883.2004 · Cited by 104 · see citing works
Microarray analysis of evolution of RNA viruses: Evidence of circulation of virulent highly divergent vaccine-derived polioviruses
Cherkasova, E., Laassri, M., Chizhikov, V., Korotkova, E., Dragunsky, E., Agol, V. I., & Chumakov, K. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1633511100 · Cited by 101 · see citing works
Self-citation
Oral Poliovirus Vaccine Evolution and Insights Relevant to Modeling the Risks of Circulating Vaccine‐Derived Polioviruses (cVDPVs)
Tebbens, R. J. D., Pallansch, M. A., Kim, J., Burns, C. C., Kew, O. M., Oberste, M. S., Diop, O. M., Wassilak, S. G. F., Cochi, S. L., & Thompson, K. M. (2013) · Risk Analysis · doi:10.1111/risa.12022 · Cited by 101 · see citing works
A Sabin 3-derived poliovirus recombinant contained a sequence homologous with indigenous human enterovirus species C in the viral polymerase coding region
Arita, M., Zhu, S.-L., Yoshida, H., Yoneyama, T., Miyamura, T., & Shimizu, H. (2005) · Journal of Virology · doi:10.1128/jvi.79.20.12650-12657.2005 · Cited by 95 · see citing works
In vivo evolution of viral virulence: switching of deformed wing virus between hosts results in virulence changes and sequence shifts
Gisder, S., Möckel, N., Eisenhardt, D., & Genersch, E. (2018) · Environmental Microbiology · doi:10.1111/1462-2920.14481 · Cited by 92 · see citing works
Vaccination against polio should not be stopped
Chumakov, K., Ehrenfeld, E., Wimmer, E., & Agol, V. I. (2007) · Nature Reviews Microbiology · doi:10.1038/nrmicro1769 · Cited by 81 · see citing works
Self-citation
Risks associated with the use of live-attenuated vaccine poliovirus strains and the strategies for control and eradication of paralytic poliomyelitis
Pliaka, V., Kyriakopoulou, Z., & Markoulatos, P. (2012) · Expert Review of Vaccines · doi:10.1586/erv.12.28 · Cited by 78 · see citing works
Parallel ClickSeq and Nanopore sequencing elucidates the rapid evolution of defective-interfering RNAs in Flock House virus
Jaworski, E. A., & Routh, A. L. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006365 · Cited by 74 · see citing works
Retrospective Analysis of a Local Cessation of Vaccination against Poliomyelitis: a Possible Scenario for the Future
Korotkova, E. A., Park, R., Cherkasova, E. A., Lipskaya, G. Y., Chumakov, K. M., Feldman, E. V., Kew, O. M., & Agol, V. I. (2003) · Journal of Virology · doi:10.1128/jvi.77.23.12460-12465.2003 · Cited by 73 · see citing works
Self-citation
Molecular Mechanisms of Poliovirus Variation and Evolution
Agol, V. I. (2006) · Current Topics in Microbiology and Immunology · doi:10.1007/3-540-26397-7_8 · Cited by 73 · see citing works
Self-citation
Vaccine-derived polioviruses
Agol, V. I. (2006) · Biologicals · doi:10.1016/j.biologicals.2006.02.007 · Cited by 68 · see citing works
Self-citation
Analysis of vaccine-virus-associated rabies cases in red foxes (Vulpes vulpes) after oral rabies vaccination campaigns in Germany and Austria
Müller, T., Bätza, H.-J., Beckert, A., Bunzenthal, C., Cox, J. H., Freuling, C. M., Fooks, A. R., Frost, J. W., Geue, L., Hoeflechner, A., et al. (2009) · Archives of Virology · doi:10.1007/s00705-009-0408-7 · Cited by 68 · see citing works
Estimating the Extent of Vaccine-Derived Poliovirus Infection
Wringe, A., Fine, P., Sutter, R. W., & Kew, O. M. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003433 · Cited by 68 · see citing works
Mechanisms of genetic variation in polioviruses
Savolainen‐Kopra, C., & Blomqvist, S. (2010) · Reviews in Medical Virology · doi:10.1002/rmv.663 · Cited by 67 · see citing works
Isolation of recombinant type 2 vaccine-derived poliovirus (VDPV) from a Nigerian child
Adu, F., Iber, J. C., Bukbuk, D. N., Gumede, N., Yang, S.-J., Jorba, J. C., Campagnoli, R. P., Sule, W. F., Yang, C.-F., Burns, C. C., et al. (2007) · Virus Research · doi:10.1016/j.virusres.2007.03.009 · Cited by 63 · see citing works
Long-Term Excretion of Vaccine-Derived Poliovirus by a Healthy Child
Martín, J. E.-S., Odoom, J. K., Tuite, G., Dunn, G., Hopewell, N., Cooper, G., Fitzharris, C., BUTLER, K. M., Hall, W. W., & Minor, P. D. (2004) · Journal of Virology · doi:10.1128/jvi.78.24.13839-13847.2004 · Cited by 63 · see citing works
Antigenic Evolution of Vaccine-Derived Polioviruses: Changes in Individual Epitopes and Relative Stability of the Overall Immunological Properties
Yakovenko, M. L., Cherkasova, E. A., Rezapkin, G. V., Ivanova, O. E., Ap, I., Eremeeva, T. P., Baykova, O. Y., Chumakov, K. M., & Agol, V. I. (2006) · Journal of Virology · doi:10.1128/jvi.80.6.2641-2653.2006 · Cited by 62 · see citing works
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Spread of Vaccine-Derived Poliovirus from a Paralytic Case in an Immunodeficient Child: an Insight into the Natural Evolution of Oral Polio Vaccine
Cherkasova, E. A., Yakovenko, M. L., Rezapkin, G. V., Korotkova, E. A., Ivanova, O. E., Eremeeva, T. P., Krasnoproshina, L. I., Romanenkova, N. I., Rozaeva, N. R., Sirota, L., et al. (2005) · Journal of Virology · doi:10.1128/jvi.79.2.1062-1070.2005 · Cited by 55 · see citing works
Self-citation
Isolation of Sabin-Like Polioviruses from Wastewater in a Country Using Inactivated Polio Vaccine
Zurbriggen, S., Tobler, K., Abril, C. E., Diedrich, S., Ackermann, M., Pallansch, M. A., & Metzler, A. E. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.02764-07 · Cited by 55 · see citing works
Vaccines: New Generation of Inactivated Poliovirus Vaccines for Universal Immunization after Eradication of Poliomyelitis
Chumakov, K., & Ehrenfeld, E. (2008) · Clinical Infectious Diseases · doi:10.1086/593310 · Cited by 54 · see citing works
Self-citation
Natural selection for rash-forming genotypes of the varicella-zoster vaccine virus detected within immunized human hosts
Quinlivan, M., Gershon, A. A., Al‐Bassam, M. M., Steinberg, S. P., LaRussa, P. S., Nichols, R. A., & Breuer, J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605688104 · Cited by 53 · see citing works
Common and diverse features of cocirculating type 2 and 3 recombinant vaccine-derived polioviruses isolated from patients with poliomyelitis and healthy children.
Joffret, M.-L., Jégouic, S., Bessaud, M., Balanant, J., Tran, C., Caro, V., Holmblat, B., Razafindratsimandresy, R., Reynes, J.-M., Rakoto-Andrianarivelo, M., et al. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis204 · Cited by 44 · see citing works
Genomic Analysis of Vaccine-Derived Poliovirus Strains in Stool Specimens by Combination of Full-Length PCR and Oligonucleotide Microarray Hybridization
Laassri, M., Dragunsky, E. M., Enterline, J. C., Eremeeva, T. P., Ivanova, O. E., Lottenbach, K. R., Belshe, R. B., & Chumakov, K. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.6.2886-2894.2005 · Cited by 43 · see citing works
Self-citation
Changes in Population Dynamics during Long-Term Evolution of Sabin Type 1 Poliovirus in an Immunodeficient Patient
Odoom, J. K., Yunus, Z., Dunn, G., Minor, P. D., & Martín, J. E.-S. (2008) · Journal of Virology · doi:10.1128/jvi.00468-08 · Cited by 42 · see citing works
Formulation of HIV-1 Tat and p24 antigens by PLA nanoparticles or MF59 impacts the breadth, but not the magnitude, of serum and faecal antibody responses in rabbits
Guillon, C., Mayol, K., Terrat, C., Compagnon, C., Primard, C., Charles, M., Delair, T., Munier, S., & Verrier, B. (2007) · Vaccine · doi:10.1016/j.vaccine.2007.08.060 · Cited by 41 · see citing works
Formaldehyde-inactivated human enterovirus 71 vaccine is compatible for co-immunization with a commercial pentavalent vaccine
Chen, C.-W., Lee, Y.-P., Wang, Y., & Yu, C. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.01.094 · Cited by 34 · see citing works
Robustness against serum neutralization of a poliovirus type 1 from a lethal epidemic of poliomyelitis in the Republic of Congo in 2010
Drexler, J. F., Grard, G., Lukashev, A. N., Kozlovskaya, L. I., Böttcher, S., Uslu, G., Reimerink, J. H. J., Gmyl, A. P., Taty, R. T., Lekana-Douki, S. E., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1323502111 · Cited by 32 · see citing works
Complete genomic characterization of an intertypic Sabin 3/Sabin 2 capsid recombinant
Dedepsidis, E., Pliaka, V., Kyriakopoulou, Z., Brakoulias, C., Levidiotou-Stefanou, S., Pratti, A., Mamuris, Z., & Markoulatos, P. (2008) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2008.00381.x · Cited by 32 · see citing works
Analysis of antigenic profiles of inactivated poliovirus vaccine and vaccine-derived polioviruses by block-ELISA method
Rezapkin, G. V., Martín, J. E.-S., & Chumakov, K. (2005) · Biologicals · doi:10.1016/j.biologicals.2004.11.001 · Cited by 32 · see citing works
Self-citation
Viral mouse models of multiple sclerosis and epilepsy: Marked differences in neuropathogenesis following infection with two naturally occurring variants of Theiler's virus BeAn strain
Bröer, S., Hage, E., Käufer, C., Gerhauser, I., Anjum, S. M. M., Li, L., Baumgärtner, W., Schulz, T. F., & Löscher, W. (2016) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.12.020 · Cited by 30 · see citing works
Retrospective Characterization of a Vaccine-Derived Poliovirus Type 1 Isolate from Sewage in Greece
Dedepsidis, E., Kyriakopoulou, Z., Pliaka, V., Kottaridi, C., Bolanaki, E., Levidiotou-Stefanou, S., Komiotis, D., & Markoulatos, P. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00535-07 · Cited by 27 · see citing works
Strength in numbers: Mechanisms of viral co-infection
Aguilera, E. R., & Pfeiffer, J. K. (2019) · Virus Research · doi:10.1016/j.virusres.2019.03.003 · Cited by 26 · see citing works
Shedding of Vaccine Viruses with Increased Antigenic and Genetic Divergence after Vaccination of Newborns with Monovalent Type 1 Oral Poliovirus Vaccine
van der Sanden, S., Pallansch, M. A., van de Kassteele, J., El-Sayed, N., Sutter, R. W., Koopmans, M., & van der Avoort, H. (2009) · Journal of Virology · doi:10.1128/jvi.02388-08 · Cited by 24 · see citing works
Improved ELISA test for determination of potency of Inactivated Poliovirus Vaccine (IPV)
Rezapkin, G. V., Dragunsky, E. M., & Chumakov, K. (2005) · Biologicals · doi:10.1016/j.biologicals.2004.11.003 · Cited by 24 · see citing works
Self-citation
Genomic Analysis of Recombinant Sabin Clinical Isolates
Paximadi, E., Karakasiliοtis, I., Mamuris, Z., Stathopoulos, C., Krikelis, V., & Markoulatos, P. (2006) · Virus Genes · doi:10.1007/s11262-005-6877-1 · Cited by 24 · see citing works
A Cluster of Paralytic Poliomyelitis Cases Due to Transmission of Slightly Diverged Sabin 2 Vaccine Poliovirus
Korotkova, E. A., Gmyl, A. P., Yakovenko, M. L., Ivanova, O. E., Eremeeva, T. P., Kozlovskaya, L. I., Shakaryan, A. K., Lipskaya, G. Y., Parshina, I. L., Loginovskikh, N. V., et al. (2016) · Journal of Virology · doi:10.1128/jvi.00277-16 · Cited by 23 · see citing works
Self-citation
Correlation between recombination junctions and RNA secondary structure elements in poliovirus Sabin strains
Dedepsidis, E., Kyriakopoulou, Z., Pliaka, V., & Markoulatos, P. (2010) · Virus Genes · doi:10.1007/s11262-010-0512-5 · Cited by 22 · see citing works
Recurrent isolation of poliovirus 3 strains with chimeric capsid protein Vp1 suggests a recombination hot-spot site in Vp1
Blomqvist, S., Savolainen‐Kopra, C., Paananen, A., Bassioni, L. E., Nasr, E. M. E. M., Firstova, L., Zamiatina, N. A., Kutateladze, T., & Roivainen, M. (2010) · Virus Research · doi:10.1016/j.virusres.2010.05.006 · Cited by 22 · see citing works
Current immunizations for travel
Kirkpatrick, B. D., & Alston, W. K. (2003) · Current Opinion in Infectious Diseases · doi:10.1097/00001432-200310000-00001 · Cited by 21 · see citing works
Microbiological Quality of Water
(2022) · Wiley eBooks · doi:10.1002/9781119820086.ch3 · Cited by 21 · see citing works
Circulation of a type 1 recombinant vaccine-derived poliovirus strain in a limited area in Romania
Combiescu, M., Guillot, S., Persu, A., Băicuş, A., Pițigoi, D., Balanant, J., Oprişan, G., Crainic, R., Delpeyroux, F., & Aubert-Combiescu, A. (2006) · Archives of Virology · doi:10.1007/s00705-006-0884-y · Cited by 18 · see citing works
Picornavirus Genetics: an Overview
Agol, V. I. (2014) · ASM Press eBooks · doi:10.1128/9781555817916.ch22 · Cited by 18 · see citing works
Self-citation
Use of a Multiple Restriction Fragment Length Polymorphism Method for Detecting Vaccine-Derived Polioviruses in Clinical Samples
Romanenkova, N. I., Guillot, S., Rozaeva, N. R., Crainic, R., Александровна, Б. М., & Delpeyroux, F. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.00017-06 · Cited by 16 · see citing works
Detection of unusual mutation within the VP1 region of different re-isolates of poliovirus Sabin vaccine
Dedepsidis, E., Karakasiliοtis, I., Paximadi, E., Kyriakopoulou, Z., Komiotis, D., & Markoulatos, P. (2006) · Virus Genes · doi:10.1007/s11262-005-0055-3 · Cited by 16 · see citing works
Excretion of Wild-Type and Vaccine-Derived Poliovirus in the Feces of Poliovirus Receptor-Transgenic Mice
Boot, H. J., Kasteel, D., Buisman, A., & Kimman, T. G. (2003) · Journal of Virology · doi:10.1128/jvi.77.11.6541-6545.2003 · Cited by 16 · see citing works
Recombinant Sabin environmental isolates in Greece and Cyprus
Paximadi, E., Karakasiliοtis, I., Papaventsis, D. C., Papageorgiou, G. T., & Markoulatos, P. (2007) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2007.03649.x · Cited by 15 · see citing works
Vaccine-associated paralytic poliomyelitis in the Russian Federation in 1998–2014
Ivanova, O. E., Eremeeva, T. P., Morozova, N. S., Shakaryan, A. K., Korotkova, E. A., Kozlovskaya, L. I., Baykova, O. Y., Krasota, A. Y., & Gmyl, A. P. (2018) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2018.08.017 · Cited by 14 · see citing works
Self-citation
Direct extraction and molecular characterization of enteroviruses genomes from human faecal samples
Bolanaki, E., Kottaridi, C., Dedepsidis, E., Kyriakopoulou, Z., Pliaka, V., Pratti, A., Levidiotou-Stefanou, S., & Markoulatos, P. (2008) · Molecular and Cellular Probes · doi:10.1016/j.mcp.2007.12.001 · Cited by 13 · see citing works
Vaccine-derived poliovirus surveillance in China during 2001–2013: the potential challenge for maintaining polio free status
Wang, H., Luo, H., Li, L., Fan, C., Hao, L., Ma, C., Su, Q., Yang, H., Reilly, K. H., Wang, H., et al. (2017) · BMC Infectious Diseases · doi:10.1186/s12879-017-2849-z · Cited by 12 · see citing works
Growth kinetic analysis of bi-recombinant poliovirus vaccine strains
Pliaka, V., Dedepsidis, E., Kyriakopoulou, Z., Papadi, G., Tsakogiannis, D., Pratti, A., Levidiotou-Stefanou, S., & Markoulatos, P. (2010) · Virus Genes · doi:10.1007/s11262-010-0448-9 · Cited by 9 · see citing works
Use of mutational pattern in 5′-NCR and VP1 regions of polioviruses for molecular diagnosis
Pliaka, V., Dedepsidis, E., Kyriakopoulou, Z., Papadopoulou, I., Levidiotou, S., & Markoulatos, P. (2007) · Molecular and Cellular Probes · doi:10.1016/j.mcp.2007.01.004 · Cited by 8 · see citing works
Polio and Its Epidemiology
Shulman, L. M. (2012) · Springer eBooks · doi:10.1007/978-1-4614-5719-0_10 · Cited by 7 · see citing works
The role of vaccine derived polioviruses in the global eradication of polio-the Nigeria experience as a case study
Okonko, I. O., Babalola, E. T., Adedeji, A. O., Onoja, A. B., Ogun, A. A., Nkang, A. O., & Adu, F. D. (2008) · Biotechnology and Molecular Biology Reviews · doi:10.5897/bmbr2008.0012 · Cited by 7 · see citing works
Vaccine-associated paralytic poliomyelitis in a child: fast transformation from Sabin-like virus to vaccine-derived poliovirus triggered an epidemiological response in two countries of the European region
Ivanova, O. E., Kozlovskaya, L. I., Eremeeva, T. P., Shakaryan, A. K., Ap, I., Baykova, O. Y., Krasota, A. Y., Shustova, E. Y., Mustafina, A. N., Morozova, N. S., et al. (2022) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2022.09.034 · Cited by 7 · see citing works
Self-citation
Three cases of paralytic poliomyelitis associated with type 3 vaccine poliovirus strains in Bulgaria
Korsun, N., Kojouharova, M., Vladimirova, N., Fiore, L., Litvinenko, I., Buttinelli, G., Fiore, S., Voynova‐Georgieva, V., Mladenova, Z., & Georgieva, D. (2009) · Journal of Medical Virology · doi:10.1002/jmv.21545 · Cited by 7 · see citing works
Correlation of mutations and recombination with growth kinetics of poliovirus vaccine strains
Pliaka, V., Kyriakopoulou, Z., Tsakogiannis, D., Ruether, I. G. A., Gartzonika, C., Levidiotou-Stefanou, S., Krikelis, A., & Markoulatos, P. (2010) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-010-1033-9 · Cited by 7 · see citing works
Vaccine-associated paralytic poliomyelitis in Russian Federation during the period of changes in vaccination schedule (2006-2013 y.y.)
Ivanova, O. E., Eremeeva, T. P., Morozova, N. S., Shakaryan, A. K., Gmyl, A. P., Yakovenko, M. L., Korotkova, E. A., Chernjavskaja, O. P., Baykova, O. Y., Silenova, O. V., et al. (2016) · Problems of Virology · doi:10.18821/0507-4088-2016-61-1-9-15 · Cited by 7 · see citing works
Self-citation
Construction of a Cloning System for the Mass Production of a Virus-Binding Protein Specific for Poliovirus Type 1
Sano, D., & Omura, T. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.5.2608-2615.2005 · Cited by 6 · see citing works
Direct extraction of Sabin poliovirus genomes from human fecal samples using a guanidine thiocyanate extraction method
Old, M. O., Martinez, C. V., Kwock, D., García, J. J., Martin, G., Chan, C. S., & Maldonado, Y. (2003) · Journal of Virological Methods · doi:10.1016/s0166-0934(03)00133-2 · Cited by 6 · see citing works
Épidémie de poliovirus circulants dérivés de souches vaccinales de type 2 en République démocratique du Congo de 2011 à 2012
Bazira, L., Coulibaly, T., Mayenga, M., Ncharre, C., Yogolelo, R., Mbule, A., Moudzeo, H., Lwamba, P., Mulumba, A., & Cabore, J. W. (2015) · Bulletin de la Société de pathologie exotique · doi:10.1007/s13149-015-0447-4 · Cited by 4 · see citing works
Evolution of Type 2 Vaccine Derived Poliovirus Lineages. Evidence for Codon-Specific Positive Selection at Three Distinct Locations on Capsid Wall
Hovi, T., Savolainen‐Kopra, C., Smura, T., Blomqvist, S., Al‐Hello, H., & Roivainen, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0066836 · Cited by 4 · see citing works
Polio and Its Epidemiology
Shulman, L. M. (2012) · Springer eBooks · doi:10.1007/978-1-4419-0851-3_839 · Cited by 4 · see citing works
PCR assays for the identification of rare recombination types from VP1 to 3D genomic region of vaccine derived poliovirus strains
Dimitriou, T. G., Pliaka, V., Kyriakopoulou, Z., Ruether, I. G. A., Tsakogiannis, D., Fountoucidou, P., Gartzonika, C., Levidiotou-Stefanou, S., & Markoulatos, P. (2013) · Molecular and Cellular Probes · doi:10.1016/j.mcp.2013.10.004 · Cited by 3 · see citing works
Retrospective molecular and phenotypic analysis of poliovirus vaccine strains isolated in Greece
Pliaka, V., Filliponi, M. E., Kyriakopoulou, Z., Ruether, I. G. A., Tsakogiannis, D., Gartzonika, C., Levidiotou-Stefanou, S., & Markoulatos, P. (2011) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2011.03470.x · Cited by 3 · see citing works
Role of Non-Polioviruses in Acute Flaccid Paralysis (AFP)
Abbasian, F., Saberbaghi, T., & Moosapour, A. (2012) · Journal of Gastroenterology and Hepatology Research · Cited by 3 · see citing works
Determination of antigenic properties of vaccine derived poliovirus strains
Pliaka, V., Achilleos, C., Kyriakopoulou, Z., Tsakogiannis, D., Ruether, I. G. A., Gartzonica, C., Levidiotou-Stefanou, S., & Markoulatos, P. (2010) · Vaccine · doi:10.1016/j.vaccine.2010.10.028 · Cited by 3 · see citing works
Poliovirus serotype 2 and coxsackievirus A promote the natural recombination of poliovirus
Qian, Y., Pu, X., Yu, Y., Yu, X., Kong, L., Liu, L., Wang, H. X., & Shen, H. (2019) · Journal of Medical Virology · doi:10.1002/jmv.25620 · Cited by 3 · see citing works
APOBEC3A is the predominant global editor of cytosines in human mRNAs and in single-strand RNA viruses
Kockler, Z. W., Bostan, H., Klimczak, L. J., Hsiao, Y.-C., Dennen, M. S., Cook, M. E., Mertz, T. M., Perelygina, L. M., Kazanov, M. D., Li, J., et al. (2026) · G3 Genes Genomes Genetics · doi:10.1093/g3journal/jkag080 · Cited by 2 · see citing works
Will the three steps for containment of poliovirus be enough to convince policy-makers?
Schoub, B. D. (2004) · Europe PMC (PubMed Central) · Cited by 2 · see citing works
Ignored Outcomes of Polio Eradication
Chakravarthi, I. (2009) · Cited by 1 · see citing works
In pursuit of intriguing puzzles
Agol, V. I. (2019) · Virology · doi:10.1016/j.virol.2019.10.006 · Cited by 1 · see citing works
Self-citation
Microarray analysis: The evolving story of oral polio vaccines
Breuer, J. (2003) · Heredity · doi:10.1038/sj.hdy.6800373 · Cited by 1 · see citing works
Genetics of Vertebrate Viruses
Pringle, C. R. (2010) · Wiley eBooks · doi:10.1002/9780470688618.taw0217 · Cited by 1 · see citing works
Genomic mutations in oral poliovirus vaccine strains : implications for the eradication of poliovirus
Pavlov, D. N. (2004) · UpSpace Institutional Repository (University of Pretoria)
Arranjos supramoleculares de oligodeoxinucleotídeos e fragmentos de bicamada catiônica: preparação, caracterização e atividade imunoadjuvante
Rozenfeld, J. H. K. (2011) · doi:10.11606/t.46.2011.tde-25042011-135215
Desarrollo de nuevos vehículos para la administración de vacunas genéticas
Csaba, N. (2005) · Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)
Quantitative analysis of trade-offs and model input sensitivities in public health
Tebbens, R. J. D. (2005)
Development of a multiplex RT-PCR assay for the identification of recombination types at different genomic regions of vaccine-derived polioviruses
Dimitriou, T. G., Kyriakopoulou, Z., Tsakogiannis, D., Fikatas, A., Gartzonika, C., Levidiotou-Stefanou, S., & Markoulatos, P. (2016) · Virus Genes · doi:10.1007/s11262-016-1333-y
Stochastische Modellierung von Exitstrategien der Poliomyelitis
Krampol, M. (2007)
Μοριακή ανίχνευση νοροϊών - πολιοϊών στο περιβάλλον. Εντοπισμός γενετικών ανασυνδυασμών και σύνδεσή τους με την αντιγραφική λειτουργία των ιϊκών στελεχών
Pliaka, V. (2010) · doi:10.12681/eadd/18309
Untranslated region-5’ and viral protein 1-based genetic stability analysis of bulk polio in Indonesia 2010-2019
Yasmon, A., Normasari, N., Fithriyah, F., & Fadilah, F. (2021) · Journal of the Medical Sciences (Berkala Ilmu Kedokteran) · doi:10.19106/jmedsci005304202106
Polio and Its Epidemiology
Shulman, L. M. (2020) · Springer eBooks · doi:10.1007/978-1-4939-2493-6_839-3
Polio and Its Epidemiology
Shulman, L. M. (2023) · Encyclopedia of sustainability science and technology series · doi:10.1007/978-1-0716-2463-0_839
Surveillance of acute flaccidparalysis and poliomyelitison some territories of Russia and South Vietnam. Part 1. Polioviruses and paralysis
Romanenkova, N. I., Nguyen, T. T. T., Rozaeva, N. R., Kanaeva, O. I., Evseeva, V. A., & Александровна, Б. М. (2023) · Russian Journal of Infection and Immunity · doi:10.15789/2220-7619-soa-3403
Ανασυνδυασμένα στελέχη πολιοϊών - θέσεις γενετικού ανασυνδυασμού
Paximadi, E. (2009) · doi:10.12681/eadd/17217
VP1 molecular evolution of type 2 immunodeficiency-related vaccine-derived polioviruses (iVDPV2) in a patient with primary immunodeficiency disease (PID)
Nejati, A., Khodakhah, F., Soheili, P., Yousefi, M., Mollaei-Kandelous, Y., Keyvanlou, M., Razaghi, M., Yaghoubzadeh, D., Zahraei, S. M., Mahmoudi, S., et al. (2026) · Virus Genes · doi:10.1007/s11262-026-02214-1
Epidemiological surveillance for poliomyelitis and acute flaccid paralysis in the Russian Federation in 2013–2024
Mikhailova, Y. M., Chirova, A. V., Cherepanova, E. A., Morozova, N. S., Shakaryan, A. K., Kozlovskaya, L. I., & Ivanova, O. E. (2026) · Journal of microbiology epidemiology immunobiology · doi:10.36233/0372-9311-863
Self-citation

Spread of Vaccine-Derived Poliovirus from a Paralytic Case in an Immunodeficient Child: an Insight into the Natural Evolution of Oral Polio Vaccine
Cherkasova, E. A., Yakovenko, M. L., Rezapkin, G. V., Korotkova, E. A., Ivanova, O. E., Eremeeva, T. P., Krasnoproshina, L. I., Romanenkova, N. I., Rozaeva, N. R., Sirota, L., et al. (2005) · Journal of Virology · doi:10.1128/jvi.79.2.1062-1070.2005 · Cited by 55 · see citing works
Self-citation
Evolution of a rare vaccine-derived multirecombinant poliovirus
Karakasiliοtis, I., Paximadi, E., & Markoulatos, P. (2005) · Journal of General Virology · doi:10.1099/vir.0.80823-0 · Cited by 28 · see citing works
Sabin Type 2 Polioviruses with Intertypic Vaccine/Vaccine Recombinant Genomes
Georgopoulou, A., & Markoulatos, P. (2001) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s100960100610 · Cited by 32 · see citing works
Changes in Population Dynamics during Long-Term Evolution of Sabin Type 1 Poliovirus in an Immunodeficient Patient
Odoom, J. K., Yunus, Z., Dunn, G., Minor, P. D., & Martín, J. E.-S. (2008) · Journal of Virology · doi:10.1128/jvi.00468-08 · Cited by 42 · see citing works
Evolution of the Sabin type 1 poliovirus in humans: characterization of strains isolated from patients with vaccine-associated paralytic poliomyelitis
Georgescu, M. M., Balanant, J., Macadam, A., Otelea, D., Combiescu, M., Combiescu, A. A., Crainic, R., & Delpeyroux, F. (1997) · Journal of Virology · doi:10.1128/jvi.71.10.7758-7768.1997 · Cited by 83 · see citing works

Authors: Cherkasova, E. A., Korotkova, E. A., Yakovenko, M. L., Ivanova, O. E., Eremeeva, T. P., Chumakov, K. M., & Agol, V. I.
Affiliations: Center for Biologics Evaluation and Research (US)
Lomonosov Moscow State University (RU)
Chumakov Institute of Poliomyelitis and Viral Encephalitides (RU)
ORCID: Cherkasova, Elena A.
Ivanova, Olga E.
Eremeeva, Tatyana P.
Agol, Vadim I.
Venue: Journal of Virology
Publisher: American Society for Microbiology
Published: 2002-07
Volume: 76
Issue: 13
Pages: 6791-6799
ISSN: 0022-538X (ISSN-L)
1098-5514
DOI: 10.1128/jvi.76.13.6791-6799.2002
PMC: PMC136293
OpenAlex: W2141343601
Cited by: 103
References: 76
Citations by year: 2026: 3 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 5 · 2015: 1 · 2014: 2 · 2013: 3 · 2012: 6
FWCI: 6.11
Type: journal article
Language: en
Open access: green
europepmc.org
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Journal of Virology (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Defense Advanced Research Projects Agency
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
Keywords: vaccine-derived poliovirus, paralytic poliomyelitis, Sabin vaccine strains, poliovirus evolution, intertypic recombination, neurovirulence, synonymous substitutions, cis-regulatory elements, adaptive mutation, antigenic determinants
MeSH terms: Base Sequence, Female, Humans, Infant, Molecular Sequence Data, Mutation, Poliomyelitis, Poliovirus Vaccine, Oral, Genome, Viral, Sequence Analysis, DNA, Poliovirus, Evolution, Molecular, Amino Acid Substitution, 5' Untranslated Regions

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Long-term circulation of vaccine-derived poliovirus that causes paralytic disease

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