Active cell death in hormone-dependent tissues

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

Kerr, J. F. R., Wyllie, A. H., & Currie, A. R. (1972) · British Journal of Cancer · doi:10.1038/bjc.1972.33 · Cited by 15,725

Cell Death: The Significance of Apoptosis

Wyllie, A. H., Kerr, J. F. R., & Currie, A. R. (1980) · International Review of Cytology · doi:10.1016/s0074-7696(08)62312-8 · Cited by 7,162

Studies on Prostatic Cancer: I. The Effect of Castration, of Estrogen and of Androgen Injection on Serum Phosphatases in Metastatic Carcinoma of the Prostate

Huggins, C., & Hodges, C. V. (2002) · Journal of Urology · doi:10.1016/s0022-5347(05)64820-3 · Cited by 3,855

The Transforming Growth Factor-beta Family

Massague, J. (1990) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.06.110190.003121 · Cited by 3,015

Plasminogen Activators, Tissue Degradation, and Cancer

(1985) · Advances in Cancer Research · doi:10.1016/s0065-230x(08)60028-7 · Cited by 2,535

Developmental cell death: morphological diversity and multiple mechanisms

Clarke, P. H. (1990) · Anatomy and Embryology · doi:10.1007/bf00174615 · Cited by 1,695

Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

Chen, Y., & Wu, H. (2010) · Chinese Science Bulletin · doi:10.1007/s11434-010-3275-4 · Cited by 1,594

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

Wyllie, A. H., Morris, R. G., Smith, A. L., & Dunlop, D. (1984) · The Journal of Pathology · doi:10.1002/path.1711420112 · Cited by 1,555

STUDIES ON PROSTATIC CANCER: II. THE EFFECTS OF CASTRATION ON ADVANCED CARCINOMA OF THE PROSTATE GLAND

HUGGINS, C. (1941) · Archives of Surgery · doi:10.1001/archsurg.1941.01210140043004 · Cited by 1,499

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

Cohen, J. J., & Duke, R. C. (1984) · The Journal of Immunology · doi:10.4049/jimmunol.132.1.38 · Cited by 1,406

Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture.

Liotta, L. A. (1986) · PubMed · Cited by 1,400

Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage

Horwitz, A., Duggan, K., Buck, C., Beckerle, M. C., & Burridge, K. (1986) · Nature · doi:10.1038/320531a0 · Cited by 1,192

A23187: A Divalent Cation Ionophore

Reed, P. W., & Lardy, H. A. (1972) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)44681-4 · Cited by 1,173

The plasminogen activator/plasmin system.

Vassalli, J. D., Sappino, A. P., & Belin, D. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115405 · Cited by 1,164

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

Basset, P., Bellocq, J. P., Wolf, C., Stoll, I., Hutin, P., Limacher, J. M., Podhajcer, O. L., Chenard, M. P., Rio, M. C., & Chambon, P. (1990) · Nature · doi:10.1038/348699a0 · Cited by 1,131

Type beta transforming growth factor: a bifunctional regulator of cellular growth.

Roberts, A. B., Anzano, M. A., Wakefield, L. M., Roche, N. S., Stern, D. F., & Sporn, M. B. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.1.119 · Cited by 1,094

The Endocrinology and Developmental Biology of the Prostate*

CUNHA, G. R., DONJACOUR, A. A., COOKE, P. S., MEE, H., BIGSBY, R. M., HIGGINS, S. J., & SUGIMURA, Y. (1987) · Endocrine Reviews · doi:10.1210/edrv-8-3-338 · Cited by 1,036

Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

Knabbe, C., Lippman, M. E., Wakefield, L. M., Flanders, K. C., Kasid, A., Derynck, R., & Dickson, R. B. (1987) · Cell · doi:10.1016/0092-8674(87)90193-0 · Cited by 975

Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis.

Laster, S. M., Wood, J. G., & Gooding, L. R. (1988) · The Journal of Immunology · doi:10.4049/jimmunol.141.8.2629 · Cited by 903

Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin

Tamkun, J. W., DeSimone, D. W., Fonda, D., Patel, R. S., Buck, C., Horwitz, A. F., & Hynes, R. O. (1986) · Cell · doi:10.1016/0092-8674(86)90744-0 · Cited by 871

The Role of Extracellular Matrix in Development

Carbonetto, S. (1985) · Trends in Neurosciences · doi:10.1016/0166-2236(85)90201-2 · Cited by 862

Role of Ca2+ in toxic cell killing

Orrenius, S., McConkey, D. J., Bellomo, G., & Nicotera, P. (1989) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(89)90029-1 · Cited by 849

Chapter 1: Interferons (IFNs)

(1986) · Advances in Cancer Research · doi:10.1016/s0065-230x(08)60034-2 · Cited by 800

Lactation : a comprehensive treatise

Larson, B. L., & Smith, V. R. (1974) · Medical Entomology and Zoology · Cited by 748

Activation of Programmed Cell Death in the Rat Ventral Prostate after Castration*

KYPRIANOU, N., & ISAACS, J. T. (1988) · Endocrinology · doi:10.1210/endo-122-2-552 · Cited by 720

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase.

Vassalli, J. D., Baccino, D., & Belin, D. (1985) · The Journal of cell biology · doi:10.1083/jcb.100.1.86 · Cited by 712

The role of calcium in cell death

Farber, J. L. (1981) · Life Sciences · doi:10.1016/0024-3205(81)90670-6 · Cited by 634

Tissue cooperation in a proteolytic cascade activating human interstitial collagenase.

HE, C. S., Wilhelm, S. M., Pentland, A. P., Marmer, B. L., Grant, G. A., Eisen, A. Z., & Goldberg, G. I. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.8.2632 · Cited by 572

Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration

McConkey, D. J., Nicotera, P., Hartzell, P., Bellomo, G., Wyllie, A. H., & Orrenius, S. (1989) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(89)90119-7 · Cited by 543

Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition.

Fey, E. G., Wan, K. M., & Penman, S. (1984) · The Journal of cell biology · doi:10.1083/jcb.98.6.1973 · Cited by 539

Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes.

Ben-Ze'ev, A., Robinson, G. S., Bucher, N. L., & Farmer, S. R. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.7.2161 · Cited by 529

Patterns of cell death.

Walker, N. I., HARMON, B. V., Gobe, G. C., & Kerr, J. F. R. (1988) · PubMed · Cited by 527

Calcium‐activated DNA fragmentation kills immature thymocytes

McConkey, D. J., Hartzell, P., Nicotera, P., & Orrenius, S. (1989) · The FASEB Journal · doi:10.1096/fasebj.3.7.2497041 · Cited by 520

Establishment of bovine mammary epithelial cells (MAC-T): An in vitro model for bovine lactation

Huynh, H. T., Robitaille, G., & Turner, J. D. (1991) · Experimental Cell Research · doi:10.1016/0014-4827(91)90422-q · Cited by 517

Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation.

Kyprianou, N., English, H. F., & Isaacs, J. T. (1990) · PubMed · Cited by 478

Induction and activation of tissue transglutaminase during programmed cell death

Fesus, L., Thomazy, V., & Falus, A. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)80430-1 · Cited by 463

Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats

Bursch, W., Paffe, S., Putz, B., Barthel, G., & Schulte-Hermann, R. (1990) · Carcinogenesis · doi:10.1093/carcin/11.5.847 · Cited by 444

Androgen Receptor Localization in Different Cell Types of the Adult Rat Prostate*

PRINS, G. S., BIRCH, L., & GREENE, G. L. (1991) · Endocrinology · doi:10.1210/endo-129-6-3187 · Cited by 436

Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation.

Kyprianou, N., English, H. F., Davidson, N. E., & Isaacs, J. T. (1991) · PubMed · Cited by 420

Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid.

Jenne, D. E., & Tschopp, J. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.18.7123 · Cited by 414

Expression of Transforming Growth Factor-β in the Rat Ventral Prostate during Castration-Induced Programmed Cell Death

Kyprianou, N., & Isaacs, J. T. (1989) · Molecular Endocrinology · doi:10.1210/mend-3-10-1515 · Cited by 410

Morphogenesis of Ductal Networks in the Mouse Prostate1

Sugimura, Y., Cunha, G. R., & Donjacour, A. A. (1986) · Biology of Reproduction · doi:10.1095/biolreprod34.5.961 · Cited by 407

Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid.

Blaschuk, O., Burdzy, K., & Fritz, I. B. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32238-5 · Cited by 401

Reversible Inhibition of Mammary Gland Growth by Transforming Growth Factor-β

Silberstein, G. B., & Daniel, C. W. (1987) · Science · doi:10.1126/science.3474783 · Cited by 400

Metalloproteinases and cancer invasion.

Liotta, L. A., & Stetler‐Stevenson, W. G. (1990) · PubMed · Cited by 397

Apoptosis: Cell death in tissue regulation

Wyllie, A. H. (1987) · The Journal of Pathology · doi:10.1002/path.1711530404 · Cited by 390

Response of glandular versus basal rat ventral prostatic epithelial cells to androgen withdrawal and replacement

English, H. F., Santen, R. J., & Lsaacs, J. T. (1987) · The Prostate · doi:10.1002/pros.2990110304 · Cited by 354

Apolipoprotein J: structure and tissue distribution

De Silva, H. V., Harmony, J. A. K., Stuart, W. D., Gil, C. M., & Robbins, J. (1990) · Biochemistry · doi:10.1021/bi00474a025 · Cited by 353

The prostate: An increasing medical problem

Ballentine Carter, H., & Coffey, D. S. (1990) · The Prostate · doi:10.1002/pros.2990160105 · Cited by 352

Cascade Induction of c-fos, c-myc, and Heat Shock 70K Transcripts during Regression of the Rat Ventral Prostate Gland

Buttyan, R., Zakeri, Z., Lockshin, R., & Wolgemuth, D. (1988) · Molecular Endocrinology · doi:10.1210/mend-2-7-650 · Cited by 350

Antagonistic effect of androgen on prostatic cell death

Isaacs, J. T. (1984) · The Prostate · doi:10.1002/pros.2990050510 · Cited by 347

Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA).

Kobayashi, H., Schmitt, M., Goretzki, L., Chucholowski, N., Calvete, J., Kramer, M., Günzler, W. A., Jänicke, F., & Graeff, H. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)67767-7 · Cited by 343

Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat

May, P. C., Lampert-Etchells, M., Johnson, S. A., Poirier, J., Masters, J. N., & Finch, C. E. (1990) · Neuron · doi:10.1016/0896-6273(90)90342-d · Cited by 339

Cell death by apoptosis during involution of the lactating breast in mice and rats

Walker, N. I., Bennett, R. E., & Kerr, J. F. R. (1989) · American Journal of Anatomy · doi:10.1002/aja.1001850104 · Cited by 337

Biosynthesis and molecular cloning of sulfated glycoprotein 2 secreted by rat Sertoli cells

Collard, M. W., & Griswold, M. D. (1987) · Biochemistry · doi:10.1021/bi00386a008 · Cited by 330

Modulation of secreted proteins of mouse mammary epithelial cells by the collagenous substrata.

Lee, E. Y., Parry, G., & Bissell, M. J. (1984) · The Journal of cell biology · doi:10.1083/jcb.98.1.146 · Cited by 320

The biochemistry of cell death by apoptosis

Bursch, W., Kleine, L., & Tenniswood, M. (1990) · Biochemistry and Cell Biology · doi:10.1139/o90-160 · Cited by 318

SP-40,40, a newly identified normal human serum protein found in the SC5b-9 complex of complement and in the immune deposits in glomerulonephritis.

Murphy, B. F., Kirszbaum, L., Walker, I. D., & d'Apice, A. J. (1988) · Journal of Clinical Investigation · doi:10.1172/jci113531 · Cited by 313

Direct mitogenic effects of insulin, epidermal growth factor, glucocorticoid, cholera toxin, unknown pituitary factors and possibly prolactin, but not androgen, on normal rat prostate epithelial cells in serum-free, primary cell culture.

McKeehan, W. L., Adams, P. S., & Rosser, M. P. (1984) · PubMed · Cited by 312

Cell surface proteoglycan associates with the cytoskeleton at the basolateral cell surface of mouse mammary epithelial cells.

Rapraeger, A., Jalkanen, M., & Bernfield, M. (1986) · The Journal of cell biology · doi:10.1083/jcb.103.6.2683 · Cited by 311

Deletion of cells by apoptosis during castration-induced involution of the rat prostate

Kerr, J. F. R., & Searle, J. (1973) · Virchows Archiv B Cell Pathology · doi:10.1007/bf02889300 · Cited by 289

Cancer Metastasis: Experimental Approaches, Theoretical Concepts, and Impacts for Treatment Strategies

(1985) · Advances in Cancer Research · doi:10.1016/s0065-230x(08)60942-2 · Cited by 289

Calcium-activated DNA Fragmentation in Rat Liver Nuclei

Jones, D. P., McConkey, D. J., Nicotera, P., & Orrenius, S. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)83363-4 · Cited by 278

Identification of mRNAs Associated with Programmed Cell Death in Immature Thymocytes

Owens, G. P., Hahn, W. E., & Cohen, J. J. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.8.4177-4188.1991 · Cited by 278

Coordinated regulation of apoptosis and cell proliferation by transforming growth factor beta 1 in cultured uterine epithelial cells.

Rotello, R. J., Lieberman, R. C., Purchio, A. F., & Gerschenson, L. E. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.8.3412 · Cited by 275

Relationship between DNA fragmentation and apoptosis in the programmed cell death in the rat prostate following castration

English, H. F., Kyprianou, N., & Isaacs, J. T. (1989) · The Prostate · doi:10.1002/pros.2990150304 · Cited by 273

Autologous Down-Regulation of Androgen Receptor Messenger Ribonucleic Acid

Quarmby, V. E., Yarbrough, W. G., Lubahn, D. B., French, F. S., & Wilson, E. M. (1990) · Molecular Endocrinology · doi:10.1210/mend-4-1-22 · Cited by 268

Inhibition of DNA Fragmentation in Thymocytes and Isolated Thymocyte Nuclei by Agents That Stimulate Protein Kinase C

McConkey, D. J., Hartzell, P., Jondal, M., & Orrenius, S. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)80009-6 · Cited by 267

Clusterin (complement lysis inhibitor) forms a high density lipoprotein complex with apolipoprotein A-I in human plasma

Jenne, D. E., Lowin, B., Peitsch, M. C., Böttcher, A., Schmitz, G., & Tschopp, J. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99123-4 · Cited by 266

Hormonal Effects on Cell Proliferation in Rat Prostate

Bruchovsky, N., Lesser, B., Van Doorn, E., & Craven, S. (1976) · Vitamins & Hormones · doi:10.1016/s0083-6729(08)60951-6 · Cited by 263

Characterization and cloning of androgen-repressed mRNAs from rat ventral prostate

Léger, J. G., Montpetit, M. L., & Tenniswood, M. P. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(87)80106-7 · Cited by 253

Agents that elevate cAMP stimulate DNA fragmentation in thymocytes.

McConkey, D. J., Orrenius, S., & Jondal, M. (1990) · The Journal of Immunology · doi:10.4049/jimmunol.145.4.1227 · Cited by 252

Apoptotic hepatocytes become insoluble in detergents and chaotropic agents as a result of transglutaminase action

Fesus, L., Thomazy, V., Autuori, F., Ceru, M. P., Tarcsa, E., & Piacentini, M. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)80210-8 · Cited by 248

DNA synthesis, apoptosis, and phenotypic expression as determinants of growth of altered foci in rat liver during phenobarbital promotion.

Schulte‐Hermann, R., Timmermann-Trosiener, I., Barthel, G., et al. (1990) · PubMed · Cited by 246

Identification of mRNAs associated with programmed cell death in immature thymocytes.

Owens, G. P., Hahn, W. E., & Cohen, J. J. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.8.4177 · Cited by 241

Molecular cloning and characterization of the novel, human complement-associated protein, SP-40,40: a link between the complement and reproductive systems.

Kirszbaum, L., Sharpe, J. A., Murphy, B., d'Apice, A. J., Classon, B., Hudson, P., & Walker, I. D. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb03430.x · Cited by 238

One-chain urokinase-type plasminogen activator from human sarcoma cells is a proenzyme with little or no intrinsic activity.

Petersen, L. C., Lund, L. R., Nielsen, L. S., Danø, K., & Skriver, L. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)37940-7 · Cited by 231

Effect of Transforming Growth Factor-β1on Proliferation and Death of Rat Prostatic Cells*

MARTIKAINEN, P., KYPRIANOU, N., & ISAACS, J. T. (1990) · Endocrinology · doi:10.1210/endo-127-6-2963 · Cited by 215

The Mechanism of Action of Androgens

Mainwaring, W. I. P. (1977) · Monographs on Endocrinology · doi:10.1007/978-3-642-88429-0 · Cited by 212

Cathepsin B and cystatins: evidence for a role in cancer progression.

Sloane, B. F. (1990) · PubMed · Cited by 209

Poly(ADP-ribose) synthetase, a main acceptor of poly(ADP-ribose) in isolated nuclei.

Ogata, N., Ueda, K., Kawaichi, M., & Hayaishi, O. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)69404-4 · Cited by 200

ADP ribosylation of rat liver nucleosomal core histones.

Burzio, L. O., Riquelme, P. T., & Koide, S. S. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)30178-3 · Cited by 195

Hormonal Therapy of Prostatic Cancer

SCOTT, W. W., MENON, M., & WALSH, P. C. (1980) · Cancer · doi:10.1002/cncr.1980.45.s7.1929 · Cited by 192

Localization of Sulfated Glycoprotein-2 (Clusterin) on Spermatozoa and in the Reproductive Tract of the Male Rat1

Sylvester, S. R., Morales, C., Oko, R., & Griswold, M. D. (1991) · Biology of Reproduction · doi:10.1095/biolreprod45.1.195 · Cited by 186

A Shuttle Mechanism for DNA‐Protein Interactions: The Regulation of Poly(ADP‐ribose) Polymerase

ZAHRADKA, P., & EBISUZAKI, K. (1982) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1982.tb06912.x · Cited by 182

Chromatin changes in apoptosis

Wyllie, A. H., Beattie, G. J., & Hargreaves, A. D. (1981) · The Histochemical Journal · doi:10.1007/bf01002719 · Cited by 182

Identification of an androgen-repressed mRNA in rat ventral prostate as coding for sulphated glycoprotein 2 by cDNA cloning and sequence analysis

Bettuzzi, S., Hiipakka, R. A., Gilna, P., & Liao, S. T. (1989) · Biochemical Journal · doi:10.1042/bj2570293 · Cited by 182

Differential expression of keratins in the basal and luminal compartments of rat prostatic epithelium during degeneration and regeneration

Verhagen, A. P. M., Aalders, T. W., Ramaekers, F. C. S., Debruyne, F. M. J., & Schalken, J. A. (1988) · The Prostate · doi:10.1002/pros.2990130104 · Cited by 175

Steroid receptor-mediated cytotoxicity of an antiestrogen and an antiprogestin in breast cancer cells.

Bardon, S., Vignon, F., Montcourrier, P., & Rochefort, H. (1987) · PubMed · Cited by 173

Stimulation of endogenous endonuclease activity in hepatocytes exposed to oxidative stress

MCCONKEY, D., HARTZELL, P., NICOTERA, P., WYLLIE, A., & ORRENIUS, S. (1988) · Toxicology Letters · doi:10.1016/0378-4274(88)90069-0 · Cited by 170

Effect of transforming growth factor beta on cell death of cultured rat hepatocytes.

Oberhammer, F., Bursch, W., Parzefall, W., Breit, P., Erber, E., Stadler, M., & Schulte‐Hermann, R. (1991) · PubMed · Cited by 164

Prostatic Ductal System in Rats: Regional Variation in Morphological and Functional Activities1

Lee, C., Sensibar, J. A., Dudek, S. M., Hiipakka, R. A., & Liao, S. (1990) · Biology of Reproduction · doi:10.1095/biolreprod43.6.1079 · Cited by 164

CTL: virus control cells first and cytolytic cells second? DNA fragmentation, apoptosis and the prelytic halt hypothesis

Martz, E., & Howell, D. M. (1989) · Immunology Today · doi:10.1016/0167-5699(89)90231-4 · Cited by 163

Complete primary structure of prostatropin, a prostate epithelial cell growth factor

Crabb, J. W., Armes, L. G., Carr, S. A., Johnson, C. M., Roberts, G. D., Bordoli, R. S., & McKeehan, W. L. (1986) · Biochemistry · doi:10.1021/bi00366a003 · Cited by 161

Successive waves of apoptosis in the rat prostate after repeated withdrawal of testosterone stimulation

Sandford, N. L., Searle, J. W., & Kerr, J. F. R. (1984) · Pathology · doi:10.3109/00313028409084731 · Cited by 160

Programmed death of nonproliferating androgen-independent prostatic cancer cells.

MARTIKAINEN, P. M., Kyprianou, N., Tucker, R. W., et al. (1991) · PubMed · Cited by 158

Poly(ADP-ribosylation) in vitro. Reaction parameters and enzyme mechanism.

Ferro, A. M., & Olivera, B. M. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34453-3 · Cited by 153

Whole-Mount Autoradiography Study of DNA Synthetic Activity during Postnatal Development and Androgen-Induced Regeneration in the Mouse Prostate1

Sugimura, Y., Cunha, G. R., Donjacour, A. A., Bigsby, R. M., & Brody, J. R. (1986) · Biology of Reproduction · doi:10.1095/biolreprod34.5.985 · Cited by 149

Poly(ADP-ribosylation) of a DNA topoisomerase.

Ferro, A. M., Higgins, N. P., & Olivera, B. M. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32361-5 · Cited by 144

Transcription factor PEA3 participates in the induction of urokinase plasminogen activator transcription in murine keratinocytes stimulated with epidermal growth factor or phorbol-ester

Rørth, P., Nerlov, C., Blasi, F., & Johnsen, M. (1990) · Nucleic Acids Research · doi:10.1093/nar/18.17.5009 · Cited by 141

Role of Epithelial Cells of the Male Excurrent Duct System of the Rat in the Endocytosis or Secretion of Sulfated Glycoprotein-2 (Clusterin)1

Hermo, L., Wright, J., Oko, R. J., & Morales, C. R. (1991) · Biology of Reproduction · doi:10.1095/biolreprod44.6.1113 · Cited by 139

Human seminal clusterin (SP-40,40). Isolation and characterization.

O’Bryan, M. K., Baker, H. W. G., Saunders, J. R., Kirszbaum, L., Walker, I. D., Hudson, P. J., Liu, D. Y., Glew, M. D., D'Apice, A. J. F., & Murphy, B. F. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114594 · Cited by 138

Prostatein. A major secretory protein of the rat ventral prostate.

Lea, O. A., Petrusz, P., & French, F. S. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50537-8 · Cited by 137

Pharmacology and Potential Use of Cyproterone Acetate

Neumann, F. (1977) · Hormone and Metabolic Research · doi:10.1055/s-0028-1093574 · Cited by 137

Ketoconazole Therapy in Advanced Prostatic Cancer

Trachtenberg, J. (1984) · The Journal of Urology · doi:10.1016/s0022-5347(17)49464-x · Cited by 137

?Tissue? transglutaminase is specifically expressed in neonatal rat liver cells undergoing apoptosis upon epidermal growth factor-stimulation

Piacentini, M., Autuori, F., Dini, L., Farrace, M. G., Ghibelli, L., Piredda, L., & Fésüs, L. (1991) · Cell and Tissue Research · doi:10.1007/bf00318764 · Cited by 135

Regulation of Androgen Receptor Protein and mRNA Concentrations by Androgens in Rat Ventral Prostate and Seminal Vesicles and in Human Hepatoma Cells

Shan, L.-X., Rodríguez, M. C., & Jänne, O. A. (1990) · Molecular Endocrinology · doi:10.1210/mend-4-11-1636 · Cited by 129

Mechanisms of Growth Control in Normal and Malignant Breast Epithelium

Lippman, M. E., & Dickson, R. B. (1989) · Elsevier eBooks · doi:10.1016/b978-0-12-571145-6.50012-1 · Cited by 126

Effect of androgen on the transcription of rat prostatic binding protein genes

Pagé, M., & Parker, M. G. (1982) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(82)90099-5 · Cited by 126

Localization of basic fibroblast growth factor and transforming growth factor beta 1 in the human mammary gland.

Gomm, J., Smith, J., Ryall, G., Baillie, R., Turnbull, L. A., & Coombes, R. C. (1991) · PubMed · Cited by 122

Calcium channel antagonists delay regression of androgen‐dependent tissues and suppress gene activity associated with cell death

Connor, J. P., Sawczuk, I. S., Benson, M. C., Tomashefsky, P., O’Toole, K., Olsson, C. A., & Buttyan, R. E. (1988) · The Prostate · doi:10.1002/pros.2990130204 · Cited by 122

Flutamide Eliminates the Risk of Disease Flare in Prostatic Cancer Patients Treated with a Luteinizing Hormone-Releasing Hormone Agonist

Labrie, F., Dupont, A., Bélanger, A., & Lachance, R. (1987) · The Journal of Urology · doi:10.1016/s0022-5347(17)43380-5 · Cited by 122

Purification and characterization of a sulfated glycoprotein secreted by Sertoli cells

Griswold, M. D., Roberts, K. P., & Bishop, P. D. (1986) · Biochemistry · doi:10.1021/bi00371a003 · Cited by 119

Isolation and Characterization of Transcripts Induced by Androgen Withdrawal and Apoptotic Cell Death in the Rat Ventral Prostate

Briehl, M. M., & Miesfeld, R. L. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-10-1381 · Cited by 118

SP-40,40 is an inhibitor of C5b-6-initiated haemolysis

Murphy, B. F., Saunders, J. R., O’Bryan, M. K., Kirszbaum, L., Walker, I. D., & d’Apice, A. J. F. (1989) · International Immunology · doi:10.1093/intimm/1.5.551 · Cited by 115

Role of epithelial‐stromal interactions in the control of gene expression in the prostate: An hypothesis

Tenniswood, M. (1986) · The Prostate · doi:10.1002/pros.2990090407 · Cited by 115

Castration Enhances Expression of Glial Fibrillary Acidic Protein and Sulfated Glycoprotein-2 in the Intact and Lesion-Altered Hippocampus of the Adult Male Rat

Day, J. R., Laping, N. J., McNeill, T. H., Schreiber, S. S., Pasinetti, G. M., & Finch, C. E. (1990) · Molecular Endocrinology · doi:10.1210/mend-4-12-1995 · Cited by 113

Stromelysin/transin and tumor progression.

Matrisian, L. M., & Bowden, G. T. (1990) · PubMed · Cited by 104

Growth factor control of extracellular proteolysis

Rifkin, D. B., Moscatelli, D., Bízik, J., Quarto, N., Blei, F., Dennis, P. A., Flaumenhaft, R. C., & Mignatti, P. (1990) · Cell Differentiation and Development · doi:10.1016/0922-3371(90)90045-x · Cited by 101

Regulation of rat mammary gene expression by extracellular matrix components

Blum, J. L., Zeigler, M. E., & Wicha, M. S. (1987) · Experimental Cell Research · doi:10.1016/0014-4827(87)90274-6 · Cited by 98

Biological and Clinical Significance of Cathepsin D in Breast Cancer

Rochefort, H. (1992) · Acta Oncologica · doi:10.3109/02841869209088891 · Cited by 97

The primary structure of glycoprotein III from bovine adrenal medullary chromaffin granules. Sequence similarity with human serum protein-40,40 and rat Sertoli cell glycoprotein.

Palmer, D. J., & Christie, D. L. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39193-8 · Cited by 96

Quantitative determination of prostatic epithelial and stromal hyperplasia by a new technique. Biomorphometrics.

Deklerk, D. P., & Coffey, D. S. (1978) · PubMed · Cited by 95

Chemotherapy versus tamoxifen versus chemotherapy plus tamoxifen in node-positive, estrogen receptor-positive breast cancer patients: results of a multicentric Italian study. Breast Cancer Adjuvant Chemo-Hormone Therapy Cooperative Group.

Boccardo, F., RUBAGOTTI, A., Bruzzi, P., Cappellini, M. D., Isola, G., Nenci, I., PIFFANELLI, A., Scanni, A., Sismondi, P., & Santi, L. (1990) · Journal of Clinical Oncology · doi:10.1200/jco.1990.8.8.1310 · Cited by 94

Studies on mammary gland involution

Helminen, H. J., & Ericsson, J. L. E. (1968) · Journal of Ultrastructure Research · doi:10.1016/s0022-5320(68)80070-x · Cited by 88

In vivo accumulation of sulfated glycoprotein 2 mRNA in rat thymocytes upon dexamethasone-induced cell death

Bettuzzi, S., Troiano, L., Davalli, P., Tropea, F., Ingletti, M. C., Grassilli, E., Monti, D., Corti, A., & Franceschi, C. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)91637-r · Cited by 86

Effect of MK‐906, a Specific 5α‐reductase Inhibitor, on Serum Androgens and Androgen Conjugates in Normal Men

Rittmaster, R. S., Stoner, E., Thompson, D. L., Nance, D. M., & Lasseter, K. C. (1989) · Journal of Andrology · doi:10.1002/j.1939-4640.1989.tb00097.x · Cited by 85

Clinical effect of aminoglutethimide, medical adrenalectomy, in treatment of 43 patients with advanced prostatic carcinoma

Drago, J. R., Santen, R. J., Lipton, A., Worgul, T. J., Harvey, H. A., Boucher, A. E., Manni, A., & Rohner, T. J. (1984) · Cancer · doi:10.1002/1097-0142(19840401)53:7<1447::aid-cncr2820530703>3.0.co;2-g · Cited by 85

Collagenous substrata regulate the nature and distribution of glycosaminoglycans produced by differentiated cultures of mouse mammary epithelial cells

Parry, G., Lee, E., Farson, D., Koval, M. H., & Bissell, M. J. (1985) · Experimental Cell Research · doi:10.1016/0014-4827(85)90556-7 · Cited by 84

Transforming Growth Factor‐β: A Family of Growth Regulatory Peptides

Miller, D. A., Pelton, R. W., Derynck, R., & Moses, H. L. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb16113.x · Cited by 84

Structural analysis of clusterin and its subunits in ram rete testis fluid

Cheng, C. Y., Mathur, P. P., & Grima, J. (1988) · Biochemistry · doi:10.1021/bi00411a026 · Cited by 83

Gene expression in response to acute unilateral ureteral obstruction

Sawczuk, I. S., Hoke, G. P., Olsson, C. A., Connor, J. P., & Buttyan, R. E. (1989) · Kidney International · doi:10.1038/ki.1989.128 · Cited by 82

Searching For the Function of Tissue Transglutaminase: Its Possible Involvement in the Biochemical Pathway of Programmed Cell Death

Fésüs, L., & Thomázy, V. A. (1988) · Springer eBooks · doi:10.1007/978-1-4684-9042-8_10 · Cited by 81

Effect of chronic adrenalectomy on neuron loss and distribution of sulfated glycoprotein-2 in the dentate gyrus of prepubertal rats

McNeill, T. H., Masters, J. N., & Finch, C. E. (1991) · Experimental Neurology · doi:10.1016/0014-4886(91)90062-h · Cited by 75

Similar Actions of Glucocorticoids and Calcium on the Regulation of Apoptosis in S49 Cells

Caron‐Leslie, L. M., & Cidlowski, J. A. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-8-1169 · Cited by 73

Factors predicting the response of patients with advanced breast cancer to endocrine (Megace) therapy

Robertson, J. F. R., Williams, M. R., Todd, J. H., Nicholson, R. I., Morgan, D. A. L., & Blamey, R. W. (1989) · European Journal of Cancer and Clinical Oncology · doi:10.1016/0277-5379(89)90259-9 · Cited by 72

Characterization of a human high density lipoprotein-associated protein, NA1/NA2. Identity with SP-40,40, an inhibitor of complement-mediated cytolysis.

James, R. W., Hochstrasser, A.-C., Borghini, I., Martin, B. M., Pometta, D., & Hochstrasser, D. F. (1991) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.11.3.645 · Cited by 70

Molecular cloning of gp 80, a glycoprotein complex secreted by kidney cells in vitro and in vivo. A link to the reproductive system and to the complement cascade

Hartmann, K., Rauch, J., Urban, J., Parczyk, K., Diel, P. R., Pilarsky, C. P., Appel, D., Haase, W., Mann, K., & Weller, A. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)92907-8 · Cited by 66

Diverse Secretory Patterns of Clusterin by Epididymis and Prostate/Seminal Vesicles Undergoing Cell Regression after Orchiectomy*

Grima, J., Zwain, I. H., Lockshin, R. A., Bardin, C. W., & Cheng, C. Y. (1990) · Endocrinology · doi:10.1210/endo-126-6-2989 · Cited by 66

Incorporation of SP-40,40 into the solyble membrance attack complex(SMAC, SC5b-9) of complement

Choi, N.-H., Nakano, Y., Tobe, T., Mazda, T., & Tomita, M. (1990) · International Immunology · doi:10.1093/intimm/2.5.413 · Cited by 66

Connections of intermediate filaments with the nuclear lamina and the cell periphery

Katsuma, Y., Swierenga, S. H. H., Marceau, N., & French, S. W. (1987) · Biology of the Cell · doi:10.1111/j.1768-322x.1987.tb00531.x · Cited by 65

SGP-2 expression as a genetic marker of progressive cellular pathology in experimental hydronephrosis

Connor, J. P., Buttyan, R. E., Olsson, C. A., D’Agati, V. D., TOOLE, K. M. O., & Sawczuk, I. S. (1991) · Kidney International · doi:10.1038/ki.1991.139 · Cited by 65

Response of prostate cancer cells to peptide growth factors: transforming growth factor-beta.

Wilding, G. (1991) · PubMed · Cited by 61

Identification of glutathione S-transferase Yb1 mRNA as the androgen-repressed mRNA by cDNA cloning and sequence analysis.

Chang, C.-S., Saltzman, A. G., Sorensen, N. S., Hiipakka, R. A., & Liao, S. S. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)45291-x · Cited by 58

Localization of terminal complement components, S-protein and SP-40,40 in renal biopsies

Murphy, B. F., Davies, D. J., Morrow, W., & d’Apice, A. J. F. (1989) · Pathology · doi:10.3109/00313028909061073 · Cited by 58

Growth Stimulation and Differential Regulation of Transforming Growth Factor-β1 (TGFβ1), TGFβ2, and TGFβ3 Messenger RNA Levels by Norethindrone in MCF-7 Human Breast Cancer Cells

Jeng, M., & Jordan, V. C. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-8-1120 · Cited by 57

Biological and clinical significance of cathepsin D in breast cancer.

Rochefort, H. (1990) · PubMed · Cited by 56

Corticosterone differentially regulates the bilateral response of astrocyte mRNAs in the hippocampus to entorhinal cortex lesions in male rats

Laping, N. J., Nichols, N. R., Day, J. R., & Finch, C. E. (1991) · Molecular Brain Research · doi:10.1016/0169-328x(91)90087-e · Cited by 54

Endocrine effects of high-dose ketoconazole therapy in advanced prostatic cancer

Heyns, W., Drochmans, A., van der Schueren, E., & Verhoeven, G. (1985) · European Journal of Endocrinology · doi:10.1530/acta.0.1100276 · Cited by 54

Expression of a novel gene encoding a 51.5 kD precursor protein is induced by different retroviral oncogenes in quail neuroretinal cells.

Michel, D., Gillet, G., Volovitch, M., Pessac, B., Calothy, G., & Brun, G. (1989) · PubMed · Cited by 54

Characterization of multiple forms of prostatropin (prostate epithelial cell growth factor) from bovine brain

Crabb, J. W., Armes, L. G., Johnson, C. M., & McKeehan, W. L. (1986) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(86)90455-9 · Cited by 51

Regulation of prostatic steroid binding protein mRNAs by testosterone

Zhang, Y., & Parker, M. G. (1985) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(85)90078-4 · Cited by 49

Zoladex: Endocrine and therapeutic effects in post-menopausal breast cancer

Harris, A. L., Carmichael, J., Cantwell, B. M. J., et al. (1989) · British Journal of Cancer · doi:10.1038/bjc.1989.19 · Cited by 48

Role of the cytoskeleton in laminin induced mammary gene expression

Blum, J. L., & Wicha, M. S. (1988) · Journal of Cellular Physiology · doi:10.1002/jcp.1041350103 · Cited by 47

Proliferative and secretory activity in the pregnant and lactating human breast

Battersby, S., & Anderson, T. J. (1988) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/bf00718610 · Cited by 46

Androgen-induced messenger RNA in rat ventral prostate. Translation, partial purification, and preliminary characterization of the mRNAs encoding the components of prostatic binding protein.

Peeters, B., Mous, J., Rombauts, W., & Heyns, W. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)43677-0 · Cited by 45

Degradation of cells dying by apoptosis leads to accumulation of ε(γ‐glutamyl)lysine isodipeptide in culture fluid and blood

Fésüs, L., Tarcsa, E., Kedei, N., Autuori, F., & Piacentini, M. (1991) · FEBS Letters · doi:10.1016/0014-5793(91)80773-v · Cited by 42

Investigation of the combination of the agonist D‐Trp‐6‐LH‐RH and the antiandrogen flutamide in the treatment of dunning R‐3327H prostate cancer model

Redding, T. W., & Schally, A. V. (1985) · The Prostate · doi:10.1002/pros.2990060302 · Cited by 39

Androgen and collagen as growth regulators of the rat ventral prostate

Müntzing, J. (1980) · The Prostate · doi:10.1002/pros.2990010110 · Cited by 37

Combined long‐term treatment with an LHRH agonist and a pure antiandrogen blocks androgenic influence in the rat

Lefebvre, F. A., Séguin, C., Bèlanger, A., Caron, S., Sairam, M. R., Raynaud, J., & Labrie, F. (1982) · The Prostate · doi:10.1002/pros.2990030606 · Cited by 36

Phase II trial with D‐Trp‐6‐LH‐RH in prostatic carcinoma: Comparison with other hormonal agents

Mathé, G., Schwarzenberg, L., VoVan, M. L., Machover, D., Misset, J. L., Court, B., Bouchard, P., Pappo, E., Schally, A. V., Comaru‐Schally, A. M., et al. (1986) · The Prostate · doi:10.1002/pros.2990090404 · Cited by 28

The effect of extracellular matrix interactions on morphologic transformation

Pienta, K. J., Murphy, B. C., Getzenberg, R. H., & Coffey, D. S. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)91374-l · Cited by 26

Modifications of the intermediate filament and nuclear matrix networks by the extracellular matrix

Getzenberg, R. H., Pienta, K. J., Huang, E. Y., Murphy, B., & Coffey, D. S. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)91375-m · Cited by 26

Intermediate filament expression and the progression of prostatic cancer as studied in the dunning R‐3327 rat prostatic carcinoma system

Ramaekers, F. C. S., Verhagen, A. P. M., Isaacs, J. T., Feitz, W. F. J., Moesker, O., Schaart, G., Schalken, J. A., & Vooijs, G. P. (1989) · The Prostate · doi:10.1002/pros.2990140405 · Cited by 26

High dose ketoconazole: endocrine and therapeutic effects in postmenopausal breast cancer

Harris, A. L., Cantwell, B. M. J., & Dowsett, M. (1988) · British Journal of Cancer · doi:10.1038/bjc.1988.247 · Cited by 24

Endocrine therapy: where do we stand and where are we going?

Fh, S. (1991) · PubMed · Cited by 21

Shape-dependent regulation of cytoskeletal protein synthesis in anchorage-dependent and anchorage-independent cells

Reiter, T., Penman, S., & Capco, D. G. (1985) · Journal of Cell Science · doi:10.1242/jcs.76.1.17 · Cited by 21

Combination therapy with flutamide and [d-Trp6]LHRH ethylamide for stage C prostatic carcinoma

Dupont, A., Labrie, F., Giguère, M., Borsanyi, J.-P., Lacourcière, Y., Bergeron, N., Cusan, L., Bélanger, A., & Emond, J. (1988) · European Journal of Cancer and Clinical Oncology · doi:10.1016/0277-5379(88)90296-9 · Cited by 17

Effect of 2-week combination therapy with the luteinizing hormone-releasing hormone (LHRH) agonist [d-Trp6, des-Gly-NH210]LHRH ethylamide and the antiandrogen flutamide on prostate structure and steroid levels in the dog

Lacoste, D., Dubé, D., Bélanger, A., & Labrie, F. (1989) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(89)90202-5 · Cited by 4

Controls of Hair Follicle Cycling

Stenn, K. S., & Paus, R. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.1.449 · Cited by 1,519

Heat shock proteins in cancer: chaperones of tumorigenesis

Calderwood, S. K., Khaleque, M. A., Sawyer, D. B., & Ciocca, D. R. (2006) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2006.01.006 · Cited by 957

Molecular mechanisms of “detachment-induced apoptosis—Anoikis”

Grossmann, J. (2002) · Apoptosis · doi:10.1023/a:1015312119693 · Cited by 565

Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy

Bursch, W., Ellinger, A., Kienzl, H., Török, L., Pandey, S., Sikorska, M., Walker, R., & Hermann, R. S. (1996) · Carcinogenesis · doi:10.1093/carcin/17.8.1595 · Cited by 516

Synthesis and Functional Analyses of Nuclear Clusterin, a Cell Death Protein

Leskov, K. S., Klokov, D. Y., Li, J., Kinsella, T. J., & Boothman, D. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209233200 · Cited by 395