Brief report: A double-blind study of naltrexone in infantile autism
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Observational studies in patients with autism have shown that administration of an opioid antagonist could decrease self-injurious behavior, stereotypies, hyperactivity, and withdrawal, while increasing verbal production, social communication, proximity seeking, and eye contact.
“Observational studies in patients with autism have shown that administration of an opioid antagonist could decrease self-injurious behavior, stereotypies, hyperactivity, and withdrawal, although increasing verbal production, social communication, proximity seeking, and eye contact (47–50).”
From Oxytocin under opioid antagonism leads to supralinear enhancement of social attention (2017) · cites this paper as [49]
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Self-citationOxytocin and opioid antagonists: A dual approach to improving social behavior
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Naltrexone in infantile autism
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Self-citationPerception de la douleur chez les enfants autistes (étude prospective de 40 cas)
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Brief Psychodynamic Psychotherapies
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Psychedelic-Assisted Psychotherapy
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Complex Post-traumatic Stress Disorder
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Psychological Models for Case Formulation
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The Psychodynamics of Self-Harm
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- Authors
- Leboyer, M., Bouvard, M. P., Launay, J.-M., Tabuteau, F., Waller, D., Dugas, M., Kerdelhue, B., Lensing, P., & Panksepp, J.
- Affiliations
- Inserm (FR)
- Hôpital Robert-Debré (FR)
- Hôpital Saint-Louis (FR)
- Bowling Green State University (US)
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 1992-06
- Volume
- 22
- Issue
- 2
- Pages
- 309-319
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- OpenAlex
- W2042202819
- Cited by
- 130
- References
- 31
- Citations by year
- 2025: 4 · 2023: 1 · 2021: 35 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 3 · 2015: 2 · 2014: 2 · 2013: 3 · 2012: 1
- FWCI
- 3.98
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Keywords
- naltrexone, infantile autism, autism treatment, opioid antagonists
- MeSH terms
- Adolescent, Arginine Vasopressin, Autistic Disorder, beta-Endorphin, Child, Child, Preschool, Dopamine, Dose-Response Relationship, Drug, Double-Blind Method, Epinephrine, Female, Humans, Male, Naltrexone, Norepinephrine
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