Terpenoids: natural inhibitors of NF-κB signaling with anti-inflammatory and anticancer potential

Microtubules as a target for anticancer drugs

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NF-κB: linking inflammation and immunity to cancer development and progression

Karin, M., & Greten, F. R. (2005) · Nature reviews. Immunology · doi:10.1038/nri1703 · Cited by 3,175

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

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Integrating cell-signalling pathways with NF-κB and IKK function

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The biological action of saponins in animal systems: a review

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Carotenoid actions and their relation to health and disease

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Anatomical and chemical defenses of conifer bark against bark beetles and other pests

Franceschi, V. R., Krokene, P., Christiansen, E., & Krekling, T. (2005) · New Phytologist · doi:10.1111/j.1469-8137.2005.01436.x · Cited by 1,124

Terpene synthases and the regulation, diversity and biological roles of terpene metabolism

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Saponins, classification and occurrence in the plant kingdom

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Carotenoid Action on the Immune Response

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Synthesis and induction of apoptosis signaling pathway of ent-kaurane derivatives

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Anticancer Activity of Pristimerin in Epidermal Growth Factor Receptor 2-Positive SKBR3 Human Breast Cancer Cells

Lee, J., Yoon, I. S., Lee, M. S., Cha, E. Y., Thương, P. T., Diep, T. T., & Kim, J. R. (2013) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b12-00685 · Cited by 54

Evaluation of Anti-inflammatory and Some Possible Mechanisms of Antinociceptive Effect of Ferula assa foetida Oleo Gum Resin

Bagheri, S. M., Hedesh, S. T., Mirjalili, A., & Dashti-R, M. H. (2015) · Journal of Evidence-Based Complementary & Alternative Medicine · doi:10.1177/2156587215605903 · Cited by 54

Synthesis and Pro‐Apoptotic Activity of Novel Glycyrrhetinic Acid Derivatives

Logashenko, E. B., Salomatina, O. V., Markov, A. V., Викторовна, К. Д., Salakhutdinov, N. F., Tolstikov, G. A., Vlassov, V. V., & Аркадьевна, З. М. (2011) · ChemBioChem · doi:10.1002/cbic.201000618 · Cited by 53

The eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damage

Dörsam, B., Wu, C., Efferth, T., Kaina, B., & Fahrer, J. (2014) · Archives of Toxicology · doi:10.1007/s00204-014-1281-z · Cited by 53

Ginkgo biloba Extract Protects against Methotrexate-Induced Hepatotoxicity: A Computational and Pharmacological Approach

Kury, L. T. A., Dayyan, F., Shah, F. A., Malik, Z., Khalil, A. A. K., Alattar, A., Alshaman, R., Ali, A., & Khan, Z. (2020) · Molecules · doi:10.3390/molecules25112540 · Cited by 53

The cardioprotective effects of marrubiin, a diterpenoid found in Leonotis leonurus extracts

Mnonopi, N., Levendal, R., Davies‐Coleman, M. T., & Frost, C. L. (2011) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2011.08.041 · Cited by 53

Pristimerin, a Triterpenoid, Inhibits Tumor Angiogenesis by Targeting VEGFR2 Activation

Mu, X., Shi, W. Q., Sun, L., Han, L., Jiang, Z., & Zhang, L. (2012) · Molecules · doi:10.3390/molecules17066854 · Cited by 52

Natural products as promising targets in glioblastoma multiforme: a focus on NF-κB signaling pathway

Soukhtanloo, M., Mohtashami, E., Maghrouni, A., Mollazadeh, H., Mousavi, S. H., Roshan, M. K., Tabatabaeizadeh, S., Hosseini, A., Vahedi, M. M., Jalili‐Nik, M., et al. (2020) · Pharmacological Reports · doi:10.1007/s43440-020-00081-7 · Cited by 51

Phytochemicals suppress nuclear factor-κB signaling

Salminen, A., Kauppinen, A., & Kaarniranta, K. (2011) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e32834d3ae7 · Cited by 50

Phytochemicals as Anti-inflammatory Nutraceuticals and Phytopharmaceuticals

Howes, M. R. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805417-8.00028-7 · Cited by 51

Secondary metabolite profiling, cytotoxicity, anti-inflammatory potential and in vitro inhibitory activities of Nardostachys jatamansi on key enzymes linked to hyperglycemia, hypertension and cognitive disorders

Bose, B., Tripathy, D., Chatterjee, A., Tandon, P., & Kumaria, S. (2018) · Phytomedicine · doi:10.1016/j.phymed.2018.08.010 · Cited by 50

Host transcriptome and microbiome interaction modulates physiology of full-sibs broilers with divergent feed conversion ratio

Shah, T. M., Patel, J. G., Gohil, T. P., Blake, D. P., & Joshi, C. G. (2019) · npj Biofilms and Microbiomes · doi:10.1038/s41522-019-0096-3 · Cited by 50

Natural compound-derived epigenetic regulators targeting epigenetic readers, writers and erasers

Yang, Y., Kim, H., Li, W., & Kong, A. T. (2015) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026615666150826114359 · Cited by 52

Biological Activity of Selected Natural and Synthetic Terpenoid Lactones

Surowiak, A. K., Balcerzak, L., Lochyński, S., & Strub, D. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22095036 · Cited by 47

Anthelmintic activity of Artemisia annua L. extracts in vitro and the effect of an aqueous extract and artemisinin in sheep naturally infected with gastrointestinal nematodes

Cala, A., Ferreira, J., Chagas, A. C. D. S., Gonzalez, J. M., Rodrigues, R. A. F., Foglio, M. A., Oliveira, M. C. D. S., Sousa, I. M. D. O., Magalhães, P. M., & Barioni, W. (2014) · Parasitology Research · doi:10.1007/s00436-014-3891-z · Cited by 47

Biological, chemical and toxicological perspectives on aerial and roots of Filago germanica (L.) huds: Functional approaches for novel phyto-pharmaceuticals

Saleem, H., Htar, T. T., Naidu, R., Nawawi, N. S., Ahmad, I., Ashraf, M., & Ahemad, N. (2018) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.11.016 · Cited by 47

Synthesis and biological activity of glycyrrhetinic acid derivatives as antitumor agents

Zhou, F., Wu, G., Cai, D., Xu, B., Yan, M.-M., Ma, T., Guo, W., Zhang, W., Huang, X., Jia, X., et al. (2019) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2019.06.029 · Cited by 47

The Current State of Knowledge of Shea Butter Tree (Vitellaria paradoxa C.F.Gaertner.) for Nutritional Value and Tree Improvement in West and Central Africa

Nguekeng, P. B. C., Hendre, P. S., Tchoundjeu, Z., Kalousová, M., Tchapda, A. V. T., Kyereh, D., Masters, E. T., & Lojka, B. (2021) · Forests · doi:10.3390/f12121740 · Cited by 52

Antioxidant and anti-inflammatory activity of Ocimum labiatum extract and isolated labdane diterpenoid

Kapewangolo, P. T., Omolo, J. J., Bruwer, R., Fonteh, P., & Meyer, D. (2015) · Journal of Inflammation · doi:10.1186/s12950-015-0049-4 · Cited by 46

1,8-Cineole potentiates IRF3-mediated antiviral response in human stem cells and in an ex vivo model of rhinosinusitis

Müller, J., Greiner, J. F. W., Zeuner, M., Brotzmann, V., Schäfermann, J., Wieters, F., Widera, D., Sudhoff, H. H., Kaltschmidt, B., & Kaltschmidt, C. (2016) · Clinical Science · doi:10.1042/cs20160218 · Cited by 50

Potential anticancer activity of carvone in N2a neuroblastoma cell line

Aydın, E., Türkez, H., & Keleş, M. S. (2013) · Toxicology and Industrial Health · doi:10.1177/0748233713484660 · Cited by 44

Lupeol and its esters: NMR, powder XRD data and in vitro evaluation of cancer cell growth

Silva, A. T. M. E., Magalhães, C. G., Duarte, L. P., Mussel, W. D. N., Ruiz, A. L. T. G., Shiozawa, L., de Carvalho, J. E., Trindade, I. C., & Filho, S. A. V. (2018) · Brazilian Journal of Pharmaceutical Sciences · doi:10.1590/s2175-97902017000300251 · Cited by 45

Combination of pristimerin and paclitaxel additively induces autophagy in human breast cancer cells via ERK1/2 regulation

Lee, Y., Na, J., Lee, M., Cha, E., Sul, J. Y., Park, J., & Lee, J. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.9488 · Cited by 43

Calluna vulgaris (L.) Hull: chemical characterization, evaluation of its bioactive properties and effect on the vaginal microbiota

Mandim, F., Barros, L., Calhelha, R. C., Abreu, R. M. V., Pinela, J., Alves, M. J., Heleno, S. A., Santos, P. F., & Ferreira, I. C. F. R. (2018) · Food & Function · doi:10.1039/c8fo01910j · Cited by 45

Effect of sodium alginate-based hydrogel loaded with lutein on gut microbiota and inflammatory response in DSS-induced colitis mice

Xu, P., Luo, S., Song, J., Dai, Z., Li, D., & Wu, C. (2023) · Food Science and Human Wellness · doi:10.1016/j.fshw.2023.03.010 · Cited by 44

Potential of natural products in inflammation: biological activities, structure–activity relationships, and mechanistic targets

Guo, Y., Peng, X., Liu, F., Zhang, Q., Ding, L., Li, G., & Qiu, F. (2024) · Archives of Pharmacal Research · doi:10.1007/s12272-024-01496-z · Cited by 49

P38 MAP Kinase Mediates Apoptosis After Genipin Treatment in Non^|^ndash;Small-Cell Lung Cancer H1299 Cells via a Mitochondrial Apoptotic Cascade

Yang, X., Yao, J. J., Luo, Y., Han, Y., Wang, Z., & Du, L. (2013) · Journal of Pharmacological Sciences · doi:10.1254/jphs.12234fp · Cited by 44

Methyl galbanate, a novel inhibitor of nitric oxide production in mouse macrophage RAW264.7 cells

Kohno, S., Murata, T., Sugiura, A., Ito, C., Iranshahi, M., Hikita, K., & Kaneda, N. (2011) · Journal of Natural Medicines · doi:10.1007/s11418-010-0505-7 · Cited by 44

Effect of Estragole on Leukocyte Behavior and Phagocytic Activity of Macrophages

Silva-Comar, F. M. D. S., Wiirzler, L. A. M., Silva-Filho, S. E., Kummer, R., Pedroso, R. B., Spironello, R. A., Silva, E. L., Bersani‐Amado, C. A., & Cuman, R. K. N. (2014) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2014/784689 · Cited by 45

Chlojaponilactone B from Chloranthus japonicus: Suppression of Inflammatory Responses via Inhibition of the NF-κB Signaling Pathway

Zhao, J., Guo, Y., Yang, D., Xue, X., Liu, Q., Zhu, L., Yin, S., & Zhao, Z. (2016) · Journal of Natural Products · doi:10.1021/acs.jnatprod.6b00355 · Cited by 43

Effects of High Starch and Supplementation of an Olive Extract on the Growth Performance, Hepatic Antioxidant Capacity and Lipid Metabolism of Largemouth Bass (Micropterus salmoides)

Liang, X., Chen, P., Wu, X., Xing, S., Morais, S., He, M., Gu, X., & Xue, M. (2022) · Antioxidants · doi:10.3390/antiox11030577 · Cited by 41

Guanacastane-type diterpenoids from Coprinus radians

Ou, Y., Li, Y., Qian, X., & Shen, Y. (2012) · Phytochemistry · doi:10.1016/j.phytochem.2012.03.002 · Cited by 42

Assessment of sesquiterpene lactones isolated from Mikania plants species for their potential efficacy against Trypanosoma cruzi and Leishmania sp.

Laurella, L. C., Cerny, N., Bivona, A. E., Alberti, A. S., Giberti, G. C., Malchiodi, E. L., Martino, V. S., Catalán, C. A. N., Alonso, M. R., Cazorla, S. I., et al. (2017) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0005929 · Cited by 41

Phytochemicals as a potential source for TNF-α inhibitors

Iqbal, M., Verpoorte, R., Korthout, H. A. A. J., & Mustafa, N. R. (2012) · Phytochemistry Reviews · doi:10.1007/s11101-012-9251-7 · Cited by 41

Evaluations of Andrographolide-Rich Fractions of Andrographis paniculata with Enhanced Potential Antioxidant, Anticancer, Antihypertensive, and Anti-Inflammatory Activities

Adiguna, S. P., Panggabean, J. A., Swasono, R. T., Rahmawati, S. I., Izzati, F. N., Bayu, A., Putra, M. Y., Formisano, C., & Chianese, G. (2023) · Plants · doi:10.3390/plants12061220 · Cited by 40

Phytochemicals Targeting JAK–STAT Pathways in Inflammatory Bowel Disease: Insights from Animal Models

Moon, S. Y., Kim, K. D., Yoo, J., Lee, J., & Hwangbo, C. (2021) · Molecules · doi:10.3390/molecules26092824 · Cited by 42

Faceted phospholipid vesicles tailored for the delivery of Santolina insularis essential oil to the skin

Castangia, I., Manca, M. L., Caddeo, C., Maxia, A., Murgia, S., Pons, R., Demurtas, D., Pando, D., Falconieri, D., Peris, J., et al. (2015) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2015.05.025 · Cited by 39

Development of anticancer drugs based on the hallmarks of tumor cells

Bailón-Moscoso, N., Romero-Benavides, J. C., & Ostrosky‐Wegman, P. (2014) · Tumor Biology · doi:10.1007/s13277-014-1649-y · Cited by 44

Activation of Antioxidant Response Element in Mouse Primary Cortical Cultures with Sesquiterpene Lactones Isolated from Tanacetum parthenium

Fischedick, J. T., Standiford, M. M., Johnson, D. A., de Vos, R. C. H., Todorović, S., Banjanac, T., Verpoorte, R., & Johnson, J. A. (2012) · Planta Medica · doi:10.1055/s-0032-1315241 · Cited by 38

Preparation of Terpenoid-Invasomes with Selective Activity against S. aureus and Characterization by Cryo Transmission Electron Microscopy

Kaltschmidt, B. P., Ennen, I., Greiner, J. F. W., Dietsch, R., Patel, A. V., Kaltschmidt, B., Kaltschmidt, C., & Hütten, A. (2020) · Biomedicines · doi:10.3390/biomedicines8050105 · Cited by 37

A novel pentacyclic triterpenoid, Ilexgenin A, shows reduction of atherosclerosis in apolipoprotein E deficient mice

Liu, C., Zhao, J., Liu, Y., Huang, Y., Shen, Y., Wang, J., Sun, W., & Sun, Y. (2016) · International Immunopharmacology · doi:10.1016/j.intimp.2016.08.024 · Cited by 38

Ursolic Acid and Chronic Disease: An Overview of UA’s Effects On Prevention and Treatment of Obesity and Cancer

Mancha, A., & Slaga, T. J. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-41334-1_4 · Cited by 36

Analgesic and Anti‐Inflammatory Effects of 80% Methanol Extract ofLeonotis ocymifolia(Burm.f.) Iwarsson Leaves in Rodent Models

Alemu, A., Tadesse, W. T., Nedi, T., & Shibeshi, W. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/1614793 · Cited by 36

Topical Administration of Terpenes Encapsulated in Nanostructured Lipid-Based Systems

Lasoń, E. (2020) · Molecules · doi:10.3390/molecules25235758 · Cited by 36

Plant‐Based Modulation of Toll‐like Receptors: An Emerging Therapeutic Model

Chahal, D. S., Sivamani, R. K., Isseroff, R. R., & Dasu, M. R. K. (2012) · Phytotherapy Research · doi:10.1002/ptr.4886 · Cited by 37

A Water-Soluble Inclusion Complex of Pedunculoside with the Polymer β-Cyclodextrin: A Novel Anti-Inflammation Agent with Low Toxicity

Liu, C., Zhang, W., Yang, H., Sun, W., Gong, X., Zhao, J., Sun, Y., & Diao, G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0101761 · Cited by 36

Costunolide inhibits proinflammatory cytokines and iNOS in activated murine BV2 microglia

Dheen, S. T. (2011) · Frontiers in Bioscience-Elite · doi:10.2741/e312 · Cited by 36

Phytochemicals inhibit the immunosuppressive functions of myeloid-derived suppressor cells (MDSC): Impact on cancer and age-related chronic inflammatory disorders

Salminen, A., Kaarniranta, K., & Kauppinen, A. (2018) · International Immunopharmacology · doi:10.1016/j.intimp.2018.06.005 · Cited by 36

Two natural products, trans-phytol and (22E)-ergosta-6,9,22-triene-3β,5α,8α-triol, inhibit the biosynthesis of estrogen in human ovarian granulosa cells by aromatase (CYP19)

Guo, J., Yuan, Y. F., Lu, D., Du, B., Xiong, L., Shi, J., Yang, L., Liu, W., Yuan, X., Zhang, G., et al. (2014) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2014.05.008 · Cited by 35

Combined activity of oridonin and wogonin in advanced-stage ovarian cancer cells

Chen, S., Cooper, M., Jones, M. L., Madhuri, T. K., Wade, J., Bachelor, A., & Butler-Manuel, S. A. (2010) · Cell Biology and Toxicology · doi:10.1007/s10565-010-9176-0 · Cited by 35

Deoxypodophyllotoxin exerts both anti-angiogenic and vascular disrupting effects

Jiang, Z., Wu, M., Miao, J., Duan, H., Zhang, S., Chen, M., Sun, L., Wang, Y., Zhang, X., Zhu, X., et al. (2013) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2013.04.030 · Cited by 34

Teasaponin Ameliorates Murine Colitis by Regulating Gut Microbiota and Suppressing the Immune System Response

Yang, H., Cai, R., Kong, Z., Chen, Y., Chen, C., Qi, S., & Gu, B. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.584369 · Cited by 33

Discovery of Triterpenoids as Reversible Inhibitors of α/β-hydrolase Domain Containing 12 (ABHD12)

Parkkari, T., Haavikko, R., Laitinen, T., Navia‐Paldanius, D., Rytilahti, R., Vaara, M., Lehtonen, M., Alakurtti, S., Yli‐Kauhaluoma, J. T., Nevalainen, T., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098286 · Cited by 32

Oridonin inhibits BxPC-3 cell growth through cell apoptosis

Xu, B., Shen, W., Liu, X., Zhang, T., Ren, J., Fan, Y., & Xu, J. (2015) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmu134 · Cited by 32

In Vivo Activity of Benzoyl Ester Clerodane Diterpenoid Derivatives from Dodonaea polyandra

Simpson, B. S., Claudie, D. J., Gerber, C., Pyke, S. M., Wang, J., McKinnon, R. A., & Semple, S. J. (2011) · Journal of Natural Products · doi:10.1021/np100701s · Cited by 32

Screening of Acetylcholinesterase Inhibitory Activity of Terpenoid and Coumarin Derivatives from the Genus Ferula

Karimi, G., Iranshahi, M., Hosseinalizadeh, F., Riahi‐Zanjani, B., & Sahebkar, A. (2010) · Cited by 32

Current status of terpenoids as inflammasome inhibitors

Hortelano, S., González‐Cofrade, L., Cuadrado, I., & Heras, B. D. L. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.113739 · Cited by 34

Experimental and Pathalogical study of Pistacia atlantica , butyrate, Lactobacillus casei and their combination on rat ulcerative colitis model

Gholami, M., Ghasemi‐Niri, S. F., Maqbool, F., Baeeri, M., Memariani, Z., Pousti, I., & Abdollahi, M. R. (2016) · Pathology - Research and Practice · doi:10.1016/j.prp.2016.02.024 · Cited by 32

Torilin Inhibits Inflammation by Limiting TAK1-Mediated MAP Kinase and NF- κ B Activation

Endale, M., Kim, T., Kwak, Y.-S., Kim, N., Kim, S., Cho, J. Y., Yun, B., & Rhee, M. H. (2017) · Mediators of Inflammation · doi:10.1155/2017/7250968 · Cited by 31

Geranylgeraniol Suppresses the Expression of IRAK1 and TRAF6 to Inhibit NFκB Activation in Lipopolysaccharide-Induced Inflammatory Responses in Human Macrophage-Like Cells

Giriwono, P. E., Shirakawa, H., Ohsaki, Y., Sato, A., Aoyama, Y., Ho, H., Gotō, T., & Komai, M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20092320 · Cited by 31

Surface plasmon resonance analysis of nuclear factor-κB protein interactions with the sesquiterpene lactone helenalin

Büchele, B., Zugmaier, W., Lunov, O., Syrovets, T., Merfort, I., & Simmet, T. (2010) · Analytical Biochemistry · doi:10.1016/j.ab.2010.02.020 · Cited by 31

Small Molecule Inhibiting Nuclear Factor‐ kB Ameliorates Oxidative Stress and Suppresses Renal Inflammation in Early Stage of Alloxan‐Induced Diabetic Nephropathy in Rat

Borgohain, M. P., Lahkar, M., Ahmed, S., Chowdhury, L., Kumar, S., Pant, R., & Choubey, A. (2016) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.12718 · Cited by 31

Inhibition of Klebsiella pneumoniae growth by selected Australian plants: natural approaches for the prevention and management of ankylosing spondylitis

Winnett, V., Sirdaarta, J., White, A. R., Clarke, F. M., & Cock, I. E. (2017) · Inflammopharmacology · doi:10.1007/s10787-017-0328-1 · Cited by 39

Anti-Inflammatory Medicinal Plants of Bangladesh—A Pharmacological Evaluation

Akhtar, M. A. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.809324 · Cited by 35

Antitumoral, mutagenic and (anti)estrogenic activities of tingenone and pristimerin

Gomes, J. P. M., Cardoso, C. R. P., Varanda, E. A., Molina-Molina, J.-M., Fernández, M. F., Olea, N., arlos, I. Z., & Vilegas, W. (2011) · Revista Brasileira de Farmacognosia · doi:10.1590/s0102-695x2011005000153 · Cited by 29

Industrial-produced lemon nanovesicles ameliorate experimental colitis-associated damages in rats via the activation of anti-inflammatory and antioxidant responses and microbiota modification

Tinnirello, V., Zizzo, M. G., Conigliaro, A., Tabone, M., Ganji, N. R., Cicio, A., Bressa, C., Larrosa, M., Rappa, F., Vergilio, G., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116514 · Cited by 28

Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARαand PPARγand the Respective Bioactive Compounds

Rozema, E., Atanasov, A. G., Fakhrudin, N., Singhuber, J., Namduang, U., Heiß, E. H., Reznicek, G., Huck, C. W., Bonn, G., Dirsch, V. M., et al. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/983023 · Cited by 28

A polysaccharide from Agaricus blazei attenuates tumor cell adhesion via inhibiting E-selectin expression

Yue, L., Cui, H., Li, C., Lin, Y., Sun, Y., Niu, Y., Wen, X., & Liu, J. (2012) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2012.02.015 · Cited by 28

Effects of Oral Sea Buckthorn Oil on Tear Film Fatty Acids in Individuals With Dry Eye

Järvinen, R. L., Larmo, P. S., Setälä, N. L., Yang, B., Engblom, J., Viitanen, M. H., & Kallio, H. P. T. (2011) · Cornea · doi:10.1097/ico.0b013e3182035ad9 · Cited by 28

Novel Antitumor Invasive Actions of p-Cymene by Decreasing MMP-9/TIMP-1 Expression Ratio in Human Fibrosarcoma HT-1080 Cells

Li, J., Liu, C., & Sato, T. (2016) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b15-00827 · Cited by 28

Natural and Synthetic α,β-Unsaturated Carbonyls for Nf-κB Inhibition

Ramachandran, P. V., Yip-Schneider, M., & Schmidt, C. M. (2009) · Future Medicinal Chemistry · doi:10.4155/fmc.09.15 · Cited by 27

GC-MS headspace analysis of Terminalia ferdinandiana fruit and leaf extracts which inhibit Bacillus anthracis growth

Wright, M. H., Sirdaarta, J., White, A. R., Greene, A. C., & Cock, I. E. (2016) · Pharmacognosy Journal · doi:10.5530/pj.2017.1.14 · Cited by 27

Six herbs essential oils suppressing inflammatory responses via inhibiting COX-2/TNF-α/IL-6/NF-κB activation

Zhang, L., Liang, X., Wang, B., Lin, Z., Ye, M., Ma, R., Zheng, M., Xiang, H., & Xu, P. (2020) · Microchemical Journal · doi:10.1016/j.microc.2020.104769 · Cited by 27

Phytochemical Screening, Antioxidant and Antibacterial Properties of Extracts of Viscum continuum E. Mey. Ex Sprague, a South African Mistletoe

Mapfumari, N. S., Nogbou, N.-D., Musyoki, A. M., Gololo, S. S., Mothibe, M. E., & Bassey, K. E. (2022) · Plants · doi:10.3390/plants11162094 · Cited by 27

Gochnatia polymorpha ssp. floccosa: Bioprospecting of an anti-inflammatory phytotherapy for use during pregnancy

de David, N., Mauro, M. D. O., Gonçalves, C. A., Pesarini, J. R., Strapasson, R. L. B., Kassuya, C. A. L., Stefanello, M. É. A., Cunha‐Laura, A. L., Monreal, A. C. D., & Oliveira, R. J. (2014) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2014.04.005 · Cited by 27

Current and potential future biological uses of Saussurea costus (Falc.) Lipsch: A comprehensive review

Elnour, A. A. M., & Abdurahman, N. H. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e37790 · Cited by 26

Nuclear factor-kappa B as potential therapeutic target in human colon cancer

Plewka, D., Plewka, A., Miśkiewicz, A., Morek, M., & Bogunia, E. (2016) · Journal of Cancer Research and Therapeutics · doi:10.4103/0973-1482.180607 · Cited by 26

Pristimerin induces apoptosis of oral squamous cell carcinoma cells via G1 phase arrest and MAPK/Erk1/2 and Akt signaling inhibition

Wu, H., Li, L., Ai, Z., Yin, J., & Chen, L. (2019) · Oncology Letters · doi:10.3892/ol.2019.9903 · Cited by 26

Tea tree oil extract causes mitochondrial superoxide production and apoptosis as an anticancer agent, promoting tumor infiltrating neutrophils cytotoxic for breast cancer to induce tumor regression

Clark, A. M., Magawa, C. T., Zamora, A. C. P., Low, P., Reynolds, M., & Ralph, S. J. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111790 · Cited by 26

An examination of the Antimicrobial and Anticancer Properties of Khaya senegalensis (Desr.) A. Juss. Bark Extracts

Rabadeaux, C., Vallette, L., Sirdaarta, J., Davis, C., & Cock, I. E. (2017) · Pharmacognosy Journal · doi:10.5530/pj.2017.4.82 · Cited by 26

1,8-cineol inhibits the Wnt/β-catenin signaling pathway through GSK-3 dephosphorylation in nasal polyps of chronic rhinosinusitis patients

Bruchhage, K., Koennecke, M., Drenckhan, M., Plötze‐Martin, K., Pries, R., & Wollenberg, B. (2018) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2018.07.060 · Cited by 27

Identification of lncRNA Signature Associated With Pan-Cancer Prognosis

Bao, G., Xu, R., Wang, X., Ji, J., Wang, L., Li, W., Zhang, Q., Huang, B., Chen, A., Zhang, D., et al. (2020) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2020.3027680 · Cited by 25

Antioxidant, Anti-Inflammatory, Acute Oral Toxicity, and Qualitative Phytochemistry of The Aqueous Root Extract of Launaea cornuta (Hochst. Ex Oliv. & Hiern.)

Akimat, E. K., Omwenga, G., Moriasi, G. A., & Ngugi, M. P. (2021) · Journal of Evidence-Based Integrative Medicine · doi:10.1177/2515690x211064585 · Cited by 25

The Current and Potential Therapeutic Uses of Parthenolide

Agatonović-Kuštrin, S., & Morton, D. W. (2018) · Studies in natural products chemistry · doi:10.1016/b978-0-444-64056-7.00003-9 · Cited by 25

Pristimerin, a natural anti-tumor triterpenoid, inhibits LPS-induced TNF-α and IL-8 production through down-regulation of ROS-related classical NF-κB pathway in THP-1 cells

Hui, B., Yao, X., Zhou, Q., Wu, Z., Peng, S., & Zhang, L. (2014) · International Immunopharmacology · doi:10.1016/j.intimp.2014.06.010 · Cited by 24

Medicinal Plants of Himalayan Forests

Painuli, S., Semwal, P., Martins, N. A., & Bachheti, R. K. (2021) · Springer eBooks · doi:10.1007/978-3-030-73077-2_8 · Cited by 24

Effect and mechanism of Src tyrosine kinase inhibitor sunitinib on the drug-resistance reversal of human A549/DDP cisplatin-resistant lung cancer cell line

ZHANG, K., WANG, X., & Wang, H. (2014) · Molecular Medicine Reports · doi:10.3892/mmr.2014.2440 · Cited by 24

Phytochemical screening and anticancer activity of the aerial parts extract of Xanthium strumarium L. on HepG2 cancer cell line

Ly, H. T., Truong, T. M., Nguyen, T. T. H., Nguyen, H.-D., Zhao, Y., & Le, V. M. (2021) · Clinical Phytoscience · doi:10.1186/s40816-021-00252-w · Cited by 23

Regulation of Adipose Tissue Biology by Long-Chain Fatty Acids: Metabolic Effects and Molecular Mechanisms

Shin, S. (2022) · Journal of Obesity & Metabolic Syndrome · doi:10.7570/jomes22014 · Cited by 23

Anticlastogenic Effect of Eryngium foetidum L. Assessed by Erythrocyte Micronucleus Assay

Promkum, C., Butryee, C., Tuntipopipat, S., & Kupradinun, P. (2012) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2012.13.7.3343 · Cited by 23

Green roofs: what can we learn from desert plants?

Dirks, I., Raviv, B., Shelef, O., Hill, A. J., Amir, E., Aidoo, M. K., Hoefgen, B., Rapaport, T., Gil, H., Geta, E., et al. (2016) · Israel Journal of Ecology and Evolution · doi:10.1080/15659801.2016.1140619 · Cited by 23

Chloraserrtone A, a Sesquiterpenoid Dimer from Chloranthus serratus

Bai, B., Ye, S.-X., Yang, D., Zhu, L., Tang, G., Chen, Y., Li, G. Q., & Zhao, Z. (2019) · Journal of Natural Products · doi:10.1021/acs.jnatprod.8b00418 · Cited by 23

Effects of Aqueous and Ethanol Root Extracts of Olax subscopioidea on Inflammatory Parameters in Complete Freund’s Adjuvant-Collagen Type II Induced Arthritic Albino Rats

Ezeani, N. N., Ibiam, U. A., Orji, O. U., Igwenyi, I. O., Aloke, C., Alum, E. U., Aja, P. M., & Ugwu, O. P.-C. (2019) · Pharmacognosy Journal · doi:10.5530/pj.2019.1.4 · Cited by 22

Evaluating the efficacy of extracted squalene from seed oil in the form of microemulsion for the treatment of COVID‐19: A clinical study

Ebrahimi, M., Farhadian, N., Amiri, A. R., Hataminia, F., Soflaei, S. S., & Karimi, M. (2021) · Journal of Medical Virology · doi:10.1002/jmv.27273 · Cited by 22

Antioxidant, anti-inflammatory and antinociceptive potential of Ternstroemia sylvatica Schltdl. & Cham

Moreno-Quirós, C. V., Sánchez-Medina, A., Vázquez-Hernández, M., Reyes, A. G. H., & García-Rodríguez, R. V. (2017) · Asian Pacific Journal of Tropical Medicine · doi:10.1016/j.apjtm.2017.10.007 · Cited by 22

In Vivo Antitumor Effects of MK615 Led by PD-L1 Downregulation

Yanaki, M., Kobayashi, M., Aruga, A., Nomura, M., & Ozaki, M. (2018) · Integrative Cancer Therapies · doi:10.1177/1534735418766403 · Cited by 22

Elephantopus mollis Kunth extracts induce antiproliferation and apoptosis in human lung cancer and myeloid leukemia cells

Ngoc, T. T. B., Nga, N. T., Trinh, N. T. M., Tran, T. L., & Thảo, Đ. T. P. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2020.113222 · Cited by 22

Naturally Occurring Terpenes: A Promising Class of Organic Molecules to Address Influenza Pandemics

Al-Salihi, S. A. A., & Alberti, F. (2021) · Natural Products and Bioprospecting · doi:10.1007/s13659-021-00306-z · Cited by 21

Insights into the mechanism of natural terpenoids as NF-kB inhibitors: an overview on their anticancer potential

Jain, H., Dhingra, N., Narsinghani, T., & Sharma, R. (2016) · Experimental Oncology · doi:10.31768/2312-8852.2016.38(3):158-168 · Cited by 47

Molecular Basis of the Anti-Inflammatory Effects of Terpenoids

Heras, B. D. L., & Hortelano, S. (2009) · Inflammation & Allergy - Drug Targets · doi:10.2174/187152809787582534 · Cited by 176

Plant derived inhibitors of NF-κB

Golan‐Goldhirsh, A., & Gopas, J. (2013) · Phytochemistry Reviews · doi:10.1007/s11101-013-9293-5 · Cited by 36

Advances in studies on inhibitors of NF-κB derived from plant

Qi-la, C. (2014) · Zhongcaoyao

Naturally Occurring NF-κB Inhibitors

Nam, N. (2006) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/138955706777934937 · Cited by 440