Terpenoids: natural inhibitors of NF-κB signaling with anti-inflammatory and anticancer potential

Microtubules as a target for anticancer drugs

Jordan, M. A., & Wilson, L. (2004) · Nature Reviews Cancer · doi:10.1038/nrc1317 · Cited by 4,000

NF-κB: linking inflammation and immunity to cancer development and progression

Karin, M., & Greten, F. R. (2005) · Nature reviews. Immunology · doi:10.1038/nri1703 · Cited by 3,175

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

Sen, R., & Baltimore, D. (1986) · Cell · doi:10.1016/0092-8674(86)90346-6 · Cited by 2,754

Integrating cell-signalling pathways with NF-κB and IKK function

Perkins, N. D. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2083 · Cited by 2,350

The biological action of saponins in animal systems: a review

Francis, G., Kerem, Z., Makkar, H. P. S., & Becker, K. (2002) · British Journal Of Nutrition · doi:10.1079/bjn2002725 · Cited by 1,722

Carotenoid actions and their relation to health and disease

Krinsky, N. I., & Johnson, E. J. (2005) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2005.10.001 · Cited by 1,461

Anatomical and chemical defenses of conifer bark against bark beetles and other pests

Franceschi, V. R., Krokene, P., Christiansen, E., & Krekling, T. (2005) · New Phytologist · doi:10.1111/j.1469-8137.2005.01436.x · Cited by 1,124

Terpene synthases and the regulation, diversity and biological roles of terpene metabolism

Tholl, D. (2006) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2006.03.014 · Cited by 886

Saponins, classification and occurrence in the plant kingdom

Vincken, J., Heng, L., de Groot, C. P. G. M., & Gruppen, H. (2006) · Phytochemistry · doi:10.1016/j.phytochem.2006.10.008 · Cited by 798

Carotenoid Action on the Immune Response

Chew, B. P., & Park, J. S. (2004) · Journal of Nutrition · doi:10.1093/jn/134.1.257s · Cited by 795

Bioactive Components of Chinese Herbal Medicines in the Treatment of Glucose and Lipid Metabolism Disorders: Evidence and Potential Mechanisms

Zhang, Y., Ju, J., Jiao, L., & Yang, B. (2023) · Engineering · doi:10.1016/j.eng.2023.03.004 · Cited by 23

Anti‐Inflammatory and Antihyperalgesic Activities of Ethanolic Extract and Fruticulin A from Salvia lachnostachys Leaves in Mice

Piccinelli, A. C., Aquino, D. F. D. S., Morato, P. N., Kuraoka-Oliveira, Â. M., Strapasson, R. L. B., Santos, D., Stefanello, M. É. A., Oliveira, R. J., & Kassuya, C. A. L. (2014) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2014/835914 · Cited by 20

Multiple anticancer effects of damsin and coronopilin isolated from Ambrosia arborescens on cell cultures.

Villagomez, R., Rodrigo, G. C., Collado, I. G., Calzado, M. A., Muñóz, E., Åkesson, B., Sterner, O., Almanza, G. R., & Duan, R. (2013) · PubMed · Cited by 21

Anti-inflammatory natural products

Olajide, O. A., & Sarker, S. D. (2020) · Annual reports in medicinal chemistry · doi:10.1016/bs.armc.2020.02.002 · Cited by 21

Analysis of the transcriptome ofIsodon rubescensand key enzymes involved in terpenoid biosynthesis

Su, X., Li, Q., Chen, S., Dong, C., Hu, Y., Yin, L., & Yang, J. (2016) · Biotechnology & Biotechnological Equipment · doi:10.1080/13102818.2016.1146086 · Cited by 20

Cytotoxicity and Pro-Apoptotic, Antioxidant and Anti-Inflammatory Activities of Geopropolis Produced by the Stingless Bee Melipona fasciculata Smith

Barboza, J. R., Pereira, F. A. N., Fernandes, R. A., Vasconcelos, C. C., Cartágenes, M. D. S. D. S., Lopes, A. J. O., de Melo, A. C., Guimarães, I. D. S., da Rocha, C. Q., & Ribeiro, M. N. D. S. (2020) · Biology · doi:10.3390/biology9090292 · Cited by 20

RANDOMIZED ANTICANCER AND CYTOTOXICITY ACTIVITIES OF GUIBOURTIA COLEOSPERMA AND DIOSPYROS CHAMAETHAMNUS.

Dushimemaria, F., du Preez, I., & Mumbengegwi, D. R. (2017) · African Journal of Traditional Complementary and Alternative Medicines · doi:10.21010/ajtcam.v14i4.1 · Cited by 20

A novel natural product, britanin, inhibits tumor growth of pancreatic cancer by suppressing nuclear factor-κB activation

Li, K., Zhou, Y., Chen, Y., Zhou, L., & Liang, J. (2020) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-020-04052-w · Cited by 20

Cacalol Acetate, a Sesquiterpene from Psacalium decompositum, Exerts an Anti-inflammatory Effect through LPS/NF-KB Signaling in Raw 264.7 Macrophages

Mora-Ramiro, B., Jiménez‐Estrada, M., Zentella‐Dehesa, A., Ventura-Gallegos, J. L., Gómez-Quiroz, L. E., Rosiles-Alanís, W., Alarcón-Aguilar, F. J., & Almanza-Pérez, J. C. (2020) · Journal of Natural Products · doi:10.1021/acs.jnatprod.0c00300 · Cited by 20

Capilliposide C derived from Lysimachia capillipes Hemsl inhibits growth of human prostate cancer PC3 cells by targeting caspase and MAPK pathways

Li, R., Zhang, L., Zhang, L., Chen, D., Tian, J., Cao, L., & Zhang, L. (2014) · International Urology and Nephrology · doi:10.1007/s11255-013-0641-6 · Cited by 20

High hydrostatic pressure enhances the anti-proliferative properties of lotus bee pollen on the human prostate cancer PC-3 cells via increased metabolites

Tuoheti, T., Rasheed, H. A., Meng, L., & Dong, M. S. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2020.113057 · Cited by 19

Natural Products and Gastric Cancer: Cellular Mechanisms and Effects to Change Cancer Progression

Ning, Z., Wang, W., Jiang, H., Qiao, Z., Sun, S., Wei, Y., Xie, X., Li, H., Bi, X., & Yang, Z. (2023) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1871520623666230407082955 · Cited by 19

Development of HuMiChip for Functional Profiling of Human Microbiomes

Tu, Q., He, Z., Li, Y., Chen, Y., Deng, Y., Lin, L., Hemme, C. L., Yuan, T., Nostrand, J. D. V., Wu, L., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090546 · Cited by 21

Bupleurum chinense Roots: a Bioactivity-Guided Approach toward Saponin-Type NF-κB Inhibitors

Liu, X., Latkolik, S. L., Atanasov, A. G., Kunert, O., Pferschy‐Wenzig, E., Heiß, E. H., Malainer, C., Schinkovitz, A., Kollroser, M., Dirsch, V. M., et al. (2017) · Planta Medica · doi:10.1055/s-0043-118226 · Cited by 20

A possible anti-inflammatory mechanism of ethyl acetate extracts of Teucrium stocksianum Bioss

Shah, S. M. M. (2015) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-015-0834-x · Cited by 19

Novel action modality of the diterpenoid anisomelic acid causes depletion of E6 and E7 viral oncoproteins in HPV-transformed cervical carcinoma cells

Paul, P., Rajendran, S. K., Peuhu, E., Alshatwi, A. A., Akbarsha, M. A., Hietanen, S., & Eriksson, J. (2014) · Biochemical Pharmacology · doi:10.1016/j.bcp.2014.02.011 · Cited by 19

Diterpenoid trigonoreidon B isolated from Trigonostemon reidioides alleviates inflammation in models of LPS-stimulated murine macrophages and inflammatory liver injury in mice

Utaipan, T., Suksamrarn, A., Kaemchantuek, P., Chokchaisiri, R., Stremmel, W., Chamulitrat, W., & Chunglok, W. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.02.144 · Cited by 19

Citrus Bio-wastes: A Source of Bioactive, Functional Products and Non-food Uses

Ellouze, I. (2022) · Springer eBooks · doi:10.1007/978-3-030-84436-3_9 · Cited by 19

The genus Scorzonera L. (Asteraceae): A comprehensive review on traditional uses, phytochemistry, pharmacology, toxicology, chemotaxonomy, and other applications

Gong, Y., Shi, Z.-N., Yu, J., He, X.-F., Meng, X., Wu, Q., & Zhu, Y. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.116787 · Cited by 18

Mesosphaerum suaveolens Essential Oil Attenuates Inflammatory Response and Oxidative Stress in LPS-Stimulated RAW 264.7 Macrophages by Regulating NF-κB Signaling Pathway

Mohanta, O., Ray, A., Jena, S., Sahoo, A., Panda, S. S., Das, P. K., Nayak, S., & Panda, P. C. (2023) · Molecules · doi:10.3390/molecules28155817 · Cited by 22

Fractions and isolated compounds from Oxyanthus speciosus subsp. stenocarpus (Rubiaceae) have promising antimycobacterial and intracellular activity

Aro, A. O., Dzoyem, J. P., Awouafack, M. D., Selepe, M. A., Eloff, J. N., & McGaw, L. J. (2019) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-019-2520-x · Cited by 19

Unusual intramolecular N→O acyl group migration occurring during conjugation of (−)-DHMEQ with cysteine

Kozawa, I., Kato, K., Teruya, T., Suenaga, K., & Umezawa, K. (2009) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2009.07.123 · Cited by 17

New Approaches to Clarify Antinociceptive and Anti-Inflammatory Effects of the Ethanol Extract from Vernonia condensata Leaves

da Silva, J. B., Temponi, V. D. S., Fernandes, F. V., Alves, G. D. A. D., de Matos, D. M., Gasparetto, C. M., Ribeiro, A. D. D. C., Pinho, J. D. J. R. G. D., Alves, M. S., & de Sousa, O. V. (2011) · International Journal of Molecular Sciences · doi:10.3390/ijms12128993 · Cited by 17

The Role of the Nuclear Factor κB Pathway in the Cellular Response to Low and High Linear Energy Transfer Radiation

Hellweg, C. E., Spitta, L. F., Koch, K., Chishti, A. A., Henschenmacher, B., Diegeler, S., Konda, B., Feles, S., Schmitz, C., Berger, T., et al. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19082220 · Cited by 17

Monoterpenoids: The Next Frontier in the Treatment of Chronic Pain?

Perri, F., Coricello, A., & Adams, J. D., Jr. (2020) · J — Multidisciplinary Scientific Journal · doi:10.3390/j3020016 · Cited by 17

Anti-Inflammatory Potential of Daturaolone from Datura innoxia Mill.: In Silico, In Vitro and In Vivo Studies

Baig, M. W., Fatima, H., Akhtar, N., Hussain, H., Okla, M. K., Al-Hashimi, A., Al-Qahtani, W. H., AbdElgawad, H., & Haq, I. (2021) · Pharmaceuticals · doi:10.3390/ph14121248 · Cited by 17

Anticancer Activity of 2α, 3α, 19β, 23β-Tetrahydroxyurs-12-en-28-oic Acid (THA), a Novel Triterpenoid Isolated from Sinojackia sarcocarpa

Wang, O., Liu, S., Zou, J., Lu, L., Chen, L., Qiu, S., Li, H., & Lu, X. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021130 · Cited by 17

Essence aromatique du Géranium Odorant (Pelargonium graveolens L’Hérit.) d’Algérie : exploration des propriétés antioxydante, anti-inflammatoire et anticancéreuse (anti-angiogénique et cytotoxique), in vitro et in ovo, vis-à-vis de différentes lignées cellulaires cancéreuses métastasiques

Boukhatem, M. N., Sudha, T., Darwish, N. H. E., Nada, H. G., & Mousa, S. A. (2021) · Annales Pharmaceutiques Françaises · doi:10.1016/j.pharma.2021.07.002 · Cited by 16

Ethnobotany, phytochemistry, pharmacology, and conservation of the genus Calanthe R. Br. (Orchidaceae)

Nanjala, C., Ren, J., Mutie, F. M., Waswa, E. N., Mutinda, E. S., Odago, W. O., Mutungi, M. M., & Hu, G. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114822 · Cited by 18

Exogenous methyl jasmonate treatment induced the transcriptional responses and accumulation of volatile terpenoids in Oenanthe javanica (Blume) DC

Feng, K., Yan, Y.-J., Sun, N., Yang, Z.-Y., Zhao, S., Wu, P., & Li, L. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.131017 · Cited by 16

Effect of Glycyrrhizin on Pseudomonal Skin Infections in Human-Mouse Chimeras

Yoshida, S., Lee, J. O., Nakamura, K., Suzuki, S., Hendon, D. N., Kobayashi, M., & Suzuki, F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0083747 · Cited by 16

Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ

Carpentier, C., Barbeau, X., Azelmat, J., Vaillancourt, K., Grenier, D., Lagüe, P., & Voyer, N. (2018) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2018.10.035 · Cited by 16

Sesquiterpene lactone trilobolide activates production of interferon-γ and nitric oxide

Kmonı́čková, E., Harmatha, J., Vokáč, K., Kostecká, P., Farghali, H., & Zı́dek, Z. (2010) · Fitoterapia · doi:10.1016/j.fitote.2010.08.005 · Cited by 16

Design and synthesis of natural product derivatives with selective and improved cytotoxicity based on a sesquiterpene scaffold

Zhang, Y., Zhang, Z., Wang, B., Liu, L., & Che, Y. (2016) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2016.03.022 · Cited by 16

AMP Kinase Activation and Inhibition of Nuclear Factor-Kappa B (NF-κB) Translocation Contribute to the Anti-Inflammatory Effect of Tricin

Lee, D., & Imm, J. (2016) · Journal of Food Biochemistry · doi:10.1111/jfbc.12293 · Cited by 16

Sesquiterpenoids from Streptomyces anulatus isolated from Giraffa camelopardalis feces

Ding, N., Han, L., Jiang, Y., Li, G., Liu, J., Mu, Y., & Huang, X. (2018) · Magnetic Resonance in Chemistry · doi:10.1002/mrc.4709 · Cited by 16

Bioinspired-Metalloporphyrin Magnetic Nanocomposite as a Reusable Catalyst for Synthesis of Diastereomeric (−)-Isopulegol Epoxide: Anticancer Activity Against Human Osteosarcoma Cells (MG-63)

Dias, L. D., de Carvalho, A. L. M. B., Pinto, S. M. A., Aquino, G. L. B., Calvete, M. J. F., Rossi, L. M., Marques, M. P. M., & Pereira, M. M. (2018) · Molecules · doi:10.3390/molecules24010052 · Cited by 16

Antioxidant and antitumour activities of extracts from Patrinia villosa and its active constituents

Lei, J., Yang, C., Yang, Y., Zhang, W., & Yu, J. J. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.04.037 · Cited by 16

Phytochemical analysis, in-vitro and in-silico study of antiproliferative activity of ethyl acetate fraction of Launaea cornuta (Hochst. ex Oliv. & Hiern) C. Jeffrey against human cervical cancer cell line

Lagu, I. J. L., Nyamai, D. W., & Njeru, S. N. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1399885 · Cited by 15

Research progress on the role and inhibitors of Keap1 signaling pathway in inflammation

Ding, C., Wu, Y., Zhan, C., Naseem, A., Chen, L., Li, H., Yang, B.-Y., & Liu, Y. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112853 · Cited by 15

Therapeutic exploration of betulinic acid in chemically induced hypothyroidism

Afzal, M., Kazmi, I. A., Semwal, S., Al-Abbasi, F. A., & Anwar, F. (2013) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-013-1842-0 · Cited by 15

Phytochemicals as potential IKK-β inhibitor for the treatment of cardiovascular diseases in plant preservation: terpenoids, alkaloids, and quinones

Hua, F., Shi, L., & Zhou, P. (2019) · Inflammopharmacology · doi:10.1007/s10787-019-00640-2 · Cited by 15

Cationic Cyclization of 2-Alkenyl-1,3-dithiolanes: Diastereoselective Synthesis of trans-Decalins

Goncalves, S., Santoro, S., Nicolas, M., Wagner, A., Maillos, P., Himo, F., & Baati, R. (2011) · The Journal of Organic Chemistry · doi:10.1021/jo2001116 · Cited by 15

Side chain-functionalized aniline-derived ursolic acid derivatives as multidrug resistance reversers that block the nuclear factor-kappa B (NF-κB) pathway and cell proliferation

Huang, R.-Z., Hua, S., Liao, Z., Huang, X., & Wang, H. (2017) · MedChemComm · doi:10.1039/c7md00105c · Cited by 15

The Impact of a Phytobiotic Mixture on Broiler Chicken Health and Meat Safety

Iwiński, H., Chodkowska, K. A., Drabik, K., Batkowska, J., Karwowska, M., Kuropka, P., Szumowski, A., Szumny, A. J., & Różański, H. (2023) · Animals · doi:10.3390/ani13132155 · Cited by 14

Degradation of P-glycoprotein by pristimerin contributes to overcoming ABCB1-mediated chemotherapeutic drug resistance in vitro

Yan, Y., Wang, F., Zhao, X.-Q., Wang, X.-K., Chen, Y., Liu, H., Xie, Y., & Fu, L. (2016) · Oncology Reports · doi:10.3892/or.2016.5230 · Cited by 14

Preparation and characterization of mucoadhesive nanoparticles of poly (methyl vinyl ether-co-maleic anhydride) containing glycyrrhizic acid intended for vaginal administration

Aguilar-Rosas, I., Alcalá-Alcalá, S., Llera-Rojas, V. G., & Ganem‐Rondero, A. (2014) · Drug Development and Industrial Pharmacy · doi:10.3109/03639045.2014.980425 · Cited by 14

Valeriana wallichii DC (Maaliol Chemotype): Antinociceptive Studies on Experimental Animal Models and Possible Mechanism of Action

Sah, S. P., Mathela, C. S., & Chopra, K. (2012) · Pharmacologia · doi:10.5567/pharmacologia.2012.432.437 · Cited by 14

Optimization of physicochemical and textural properties of pizza cheese fortified with soybean oil and carrot extract

Motevalizadeh, E., Mortazavi, S. A., Milani, E., & Hooshmand-Dalir, M.-A.-R. (2018) · Food Science & Nutrition · doi:10.1002/fsn3.563 · Cited by 14

Commiphora myrrha inhibits itch‑associated histamine and IL‑31 production in stimulated mast cells

Shin, J. Y., Che, D., Cho, B., Kang, H. J., Kim, J.-S., & Jang, S. I. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.7721 · Cited by 14

Britanin Exhibits Potential Inhibitory Activity on Human Prostate Cancer Cell Lines Through PI3K/Akt/NF-κB Signaling Pathways

Zeng, Q., Zeng, Y., Zhan, Y., Nie, X., & Guo, Y. (2020) · Planta Medica · doi:10.1055/a-1211-4656 · Cited by 14

Evaluating natural compounds as potential insecticides against three economically important pests, Bemisia tabaci (Hemiptera: Aleyrodidae), Frankliniella occidentalis (Thysanoptera: Thripidae), and Myzus persicae (Hemiptera: Aphididae), on greenhouse sweet peppers

Kim, S., Lee, J.-K., Song, Y., Kang, S. C., Kim, B., Choi, I.-J., & Lee, D. (2018) · Applied Biological Chemistry · doi:10.1007/s13765-018-0362-8 · Cited by 13

Plantago squarrosa Murray extracts inhibit the growth of some bacterial triggers of autoimmune diseases: GC–MS analysis of an inhibitory extract

Omer, E. A., Elshamy, A. I., Nassar, M. I., Shalom, J., White, A. R., & Cock, I. E. (2018) · Inflammopharmacology · doi:10.1007/s10787-018-0547-0 · Cited by 13

Prospecting Pharmacologically Active Biocompounds from the Amazon Rainforest: In Vitro Approaches, Mechanisms of Action Based on Chemical Structure, and Perspectives on Human Therapeutic Use

Almada-Vilhena, A. O., dos Santos, O. V. M., Machado, M. D. A., Nagamachi, C. Y., & Pieczarka, J. C. (2024) · Pharmaceuticals · doi:10.3390/ph17111449 · Cited by 22

Analysis of the Cytotoxic Potential of Anisomelic Acid Isolated from Anisomeles malabarica

Preethy, C. P. (2013) · Scientia Pharmaceutica · doi:10.3797/scipharm.1210-15 · Cited by 12

Ethnomedicinal and phytochemical properties of sesquiterpene lactones from Dicoma (Asteraceae) and their anticancer pharmacological activities: A review

Mangisa, M., Peter, X. K., Khosa, M. C., Fouché, G., Nthambeleni, R., Senabe, J. V., Tarirai, C., & Tembu, V. J. (2021) · Scientific African · doi:10.1016/j.sciaf.2021.e00919 · Cited by 12

Geranylgeraniol Inhibits Lipopolysaccharide-Induced Inflammation in Mouse-Derived MG6 Microglial Cells via NF-κB Signaling Modulation

Saputra, W. D., Shono, H., Ohsaki, Y., Sultana, H., Komai, M., & Shirakawa, H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910543 · Cited by 12

Cationic cyclization of keto-epoxides mediated by zirconium(IV) tetrachloride: diastereoselective synthesis of cis-decalinols

Goncalves, S., Nicolas, M., Maillos, P., & Baati, R. (2011) · Tetrahedron · doi:10.1016/j.tet.2011.08.050 · Cited by 12

Effect of Natural and Semisynthetic Pseudoguianolides on the Stability of NF-κB:DNA Complex Studied by Agarose Gel Electrophoresis

Villagomez, R., Hatti‐Kaul, R., Sterner, O., Almanza, G. R., & Linares‐Pastén, J. A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0115819 · Cited by 12

The Healing Effect of N-Hexan- Dichloromethane Extract Root Onosma Bulbotrichum in Second Degree Burns.

Hemmati, A. A., Namjuyan, F., Yousefi, S., Housmand, G., Haghighian, H. K., & Rezaei, A. (2018) · Europe PMC (PubMed Central) · Cited by 12

Abdominal aortic aneurysms: clinical diagnosis and management.

Cates, J. R. (1997) · PubMed · Cited by 12

In vitro determination of anti-lipidemic, anti-inflammatory, and anti-oxidant properties and proximate composition of range of millet types and sorghum varieties in Sri Lanka

Abeysekera, W. K. S. M., Jayathilaka, S. I., Abeysekera, W. P. K. M., Senevirathne, I. G. N. H., Jayanath, N. Y., Premakumara, G. A. S., & Wijewardana, D. C. M. S. I. (2022) · Frontiers in Sustainable Food Systems · doi:10.3389/fsufs.2022.884436 · Cited by 12

Protective effect of menthol against thioacetamide-induced hepatic encephalopathy by suppressing oxidative stress and inflammation, augmenting expression of BDNF and α7-nACh receptor, and improving spatial memory

Kaboutari, M., Asle‐Rousta, M., & Mahmazi, S. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176916 · Cited by 11

In Silico Molecular Docking Analysis of α-Pinene: An Antioxidant and Anticancer Drug Obtained from Myrtus communis

Fazeli‐Nasab, B., Sayyed, R. Z., & Sobhanizadeh, A. (2021) · International Journal of Cancer Management · doi:10.5812/ijcm.89116 · Cited by 14

Anti-proliferative effects of diterpenoids from Sagittaria trifolia L. tubers on colon cancer cells by targeting the NF-κB pathway

Assani, I., Du, Y., Wang, C., Chen, L., Hou, P., Zhao, S.-F., Feng, Y., Liu, L., Sun, B., Li, Y., et al. (2020) · Food & Function · doi:10.1039/d0fo00228c · Cited by 10

A systematic review of Aspilia africana (Pers.) C.D. adams traditional medicinal uses, phytoconstituents, bioactivities, and toxicities

Gang, R., Okello, D., Ban, Y., & Kang, Y. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107590 · Cited by 11

Potential therapeutic targets for Alzheimer’s disease: Fibroblast growth factors and their regulation of ferroptosis, pyroptosis and autophagy

Li, Y., Yang, C., Liu, X., Shu, J., Zhao, N., Sun, Z., Tabish, M. S., Hong, Y., Liu, E., Wei, N., et al. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.03.009 · Cited by 10

Effect of geographical origin on yield and composition of cone essential oils of Cedrus libani A. Rich. growing in Lebanese protected areas and variability assessment in comparison with literature survey

Zgheib, R., Beyrouthy, M. E., Rayess, Y. E., Dahi, M., Nehme, N., Azzi-Achkouty, S., & Iriti, M. (2020) · Zeitschrift für Naturforschung C · doi:10.1515/znc-2019-0172 · Cited by 10

The medicinal plant Tabebuia impetiginosa potently reduces pro-inflammatory cytokine responses in primary human lymphocytes

Ryan, R. Y. M., Fernandez, A., Wong, Y., Miles, J. J., & Cock, I. E. (2021) · Scientific Reports · doi:10.1038/s41598-021-85211-8 · Cited by 10

Natural and Semi-Synthetic Pseudoguaianolides as Inhibitors of NF-κB

Villagomez, R., Collado, J. A., Muñóz, E., Almanza, G. R., & Sterner, O. (2014) · Journal of Biomedical Science and Engineering · doi:10.4236/jbise.2014.710083 · Cited by 10

Volatile oils: Potential agents for the treatment of respiratory infections

Pasdaran, A., Pasdaran, A., & Sheikhi, D. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-804543-5.00016-6 · Cited by 10

Essential oils from Tithonia diversifolia display potent anti-oedematogenic effects and inhibit acid production by cariogenic bacteria

de Sousa, I. P., Chagas‐Paula, D. A., Tiossi, R. F. J., Silva, E. D. O., Miranda, M. A., de Oliveira, R. B., Spadaro, A. C. C., Bastos, J. K., Furtado, N. A. J. C., & Costa, F. B. D. (2018) · Journal of Essential Oil Research · doi:10.1080/10412905.2018.1500315 · Cited by 11

Investigation of the anti-angiogenesis effects induced by deoxypodophyllotoxin-5-FU conjugate C069 against HUVE cells

Xiang, R., Guan, X.-W., Hui, L., Jin, Y., & Chen, S. (2017) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2017.01.051 · Cited by 10

Phytochemical Screening and Anti-Inflammatory Studies of Tapinanthus globiferus (A. Rich) Teigh. Leaves Three Extracts

Jeremiah, C., Katsayal, U. A., Nuhu, A., Anafi, S. B., Ibrahim, M. A., & Nuhu, H. D. (2019) · Pharmaceutical Sciences · doi:10.15171/ps.2019.19 · Cited by 9

Diet supplemented with Saccharomyces cerevisiae from different fermentation media modulates the faecal microbiota and the intestinal fermentative products in dogs

Bastos, T. S., Souza, C. M. M., Kaelle, G. C. B., do Nascimento, M. Q., de Oliveira, S. G., & Félix, A. P. (2023) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.13824 · Cited by 9

Plant-Derived Bioactive Compounds in Inflammation-Related Cancers: Mechanisms and Therapeutic Potential

Song, M., Zhu, X., Zhao, X., Feng, J., & Sui, X. (2026) · Plants · doi:10.3390/plants15040575 · Cited by 11

Terpenoids

Powder-George, Y. L., Ludwiczuk, A., Skalicka‐Woźniak, K., & Georgiev, M. I. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-18657-8.00006-2 · Cited by 9

Investigation of the anti-inflammatory and antinociceptive activities of Hymenocardia acida Tul. ( Hymenocardiaceae )

Sofidiya, M. O., Odukoya, O. A., Adedapo, A. A., Mbagwu, H., Afolayan, A. J., & Familoni, O. B. (2010) · AFRICAN JOURNAL OF BIOTECHNOLOGY · Cited by 9

PRELIMINARY PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF AN AYURVEDIC FORMULATION: BALARISHTAM

Rajalakshmy, M. R., & Sindhu, A. (2011) · Cited by 9

Ethnopharmacology, phytochemistry and pharmacology of potent antibacterial medicinal plants from Africa

Kuete, V. (2022) · Advances in botanical research · doi:10.1016/bs.abr.2022.08.022 · Cited by 8

Elucidating the Phytochemical Landscape of Leaves, Stems, and Tubers of Codonopsis convolvulacea through Integrated Metabolomics

Yuan, F., Yan, S., & Zhao, J. (2024) · Molecules · doi:10.3390/molecules29133193 · Cited by 8

Phytochemical analysis, toxicity assessment, and wound healing properties of Emilia sonchifolia L. leaf extract in rats

Uche, M. E., Chinyere, C. G., Ekweogu, C. N., Nwankpa, P., & Ugbogu, E. A. (2024) · South African Journal of Botany · doi:10.1016/j.sajb.2024.07.065 · Cited by 8

E-Nose and HS-SPME-GC-MS unveiling the scent signature of Ligusticum chuanxiong and its medicinal relatives

Xu, W., Zhang, C., Xu, R., Yang, J., Kong, Y., Liu, L., Tao, S., Yu, W., Liao, H., Mao, C., et al. (2025) · Frontiers in Plant Science · doi:10.3389/fpls.2025.1476810 · Cited by 8

Integrated transcriptome and metabolome analyses provide molecular insights into the transition of flower color in the rose cultivar ‘Juicy Terrazza’

Yun, X., Ren, J., Chen, Z., & Shi, D. (2025) · BMC Plant Biology · doi:10.1186/s12870-025-06794-2 · Cited by 8

Secondary metabolites in wound healing: a review of their mechanisms of action

Álvarez-Santos, N., García‐Bores, A. M., Barrera‐Oviedo, D., Hernández, T., Estrella-Parra, E. A., & Ávila-Acevedo, J. G. (2023) · Studies in natural products chemistry · doi:10.1016/b978-0-323-91253-2.00012-1 · Cited by 8

Anti-Inflammatory Natural Foods

Prabhala, H. K., Pai, C., & PRABHALA, R. H. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-397156-2.00020-x · Cited by 8

Synthesis, characterization and evaluation of antidengue activity of enantiomeric Schiff bases derived from S-substituted dithiocarbazate

Maryam, M., Tan, S. L., Crouse, K. A., Tahir, M. I. M., & Chee, H. (2020) · TURKISH JOURNAL OF CHEMISTRY · doi:10.3906/kim-2006-22 · Cited by 8

ACTIVIDAD CITOTÓXICA DEL EXTRACTO ETANÓLICO DE Gnaphalium spicatum "KETO KETO " EN CULTIVOS DE LÍNEAS CELULARES TUMORALES HUMANAS

Callacondo, D., Quispe-Mauricio, A., Lindo-Gamarra, S., & Vaisberg, A. (2008) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 8

TBK1-targeted suppression of TRIF-dependent signaling pathway of Toll-like receptors by helenalin

Shin, H.-J., & Youn, H. (2013) · Life Sciences · doi:10.1016/j.lfs.2013.09.004 · Cited by 8

Anthelmintic activity of Artemisia annua in sheep-model

Charlie‐Silva, I., Pedro, M. D. M., Ilza, M. D. O. S., Mary, A. F., Leonardecz, E., Sérgio, N. E., & Ana, C. D. S. C. (2017) · Journal of Medicinal Plants Research · doi:10.5897/jmpr2016.6318 · Cited by 8

Ethanol Extract of Brassica rapa ssp . pekinensis Suppresses Tumor Necrosis Factor- α -Induced Inflammatory Response in Human Umbilical Vein Endothelial Cells

Joo, H. K., Choi, S., Lee, Y. R., Lee, E. O., Park, M. S., Lim, Y. P., Park, J., & Jeon, B. H. (2017) · Journal of Medicinal Food · doi:10.1089/jmf.2016.3869 · Cited by 8

Bacillus velezensis NDB mitigates Aeromonas hydrophila-induced enteritis in black sea bream (Acanthopagrus schlegelii) by enhancing intestinal immunity and modulating gut microbiota

Zhang, Z., Wang, Z., Wang, Z., Yi, H., Su, X., Wang, R., Ming, T., & Xu, J. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1660494 · Cited by 8

A NETWORK PHARMACOLOGY-BASED TREATMENT ANALYSIS OF LUTEOLIN FOR REGULATING PYROPTOSIS IN ACUTE LUNG INJURY

Zhang, D., Li, Y., Jiang, W., Li, W., Yuan, X., & Lin, Z. (2023) · Shock · doi:10.1097/shk.0000000000002168 · Cited by 9

Comparison of the antibacterial activity of Australian Terminalia spp. extracts against Klebsiella pneumoniae: a potential treatment for ankylosing spondylitis

Courtney, R., & Cock, I. E. (2022) · Inflammopharmacology · doi:10.1007/s10787-021-00914-8 · Cited by 7

Determination of Terpenes in Traditional Chinese Medicine (TCM) by Comprehensive Two-Dimensional Gas Chromatography – Mass Spectrometry (GC × GC) Coupled to High-Resolution Quadrupole Time-of-Flight Mass Spectrometry (QTOFMS) with Orthogonal Partial Least Squares – Discrimination Analysis (OPLS-DA)

Zhou, X., Chen, B., Li, R., & Xiang, Z. (2022) · Analytical Letters · doi:10.1080/00032719.2022.2066685 · Cited by 7

Natural compounds from traditional Chinese medicine regulating stem cell fate: Identification and therapeutic potential

Zhao, Z., Ma, Y., Wang, S., Zhou, M., Tian, Y., Yang, L., Gu, J. H., & Tan, R. (2025) · Chinese Herbal Medicines · doi:10.1016/j.chmed.2025.05.002 · Cited by 6

Advances in Terpenoid Biosynthesis: Chemical Diversity and Emerging Industrial Applications

Patil, H. S., Baviskar, A. S., Dinore, J. M., & Yelwande, A. A. (2025) · Sciences of Phytochemistry · doi:10.58920/sciphy0402310 · Cited by 6

Relevance of Phytochemical Taste for Anti-Cancer Activity: A Statistical Inquiry

Grădinaru, T.-C., Gîlcă, M., Vlad, A., & Dragoș, D. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216227 · Cited by 6

Cerium(IV) based oxidative free radical cyclization of active methylene compounds with some cyclic alkenes: A useful annulation method for terpene functionalization

Světlík, J., Tureček, F., Hartwich, K., Kozieł, K., Pakulski, P., Pałasz, A., Kalinowska‐Tłuścik, J., & Cież, D. (2019) · Tetrahedron · doi:10.1016/j.tet.2019.03.039 · Cited by 6

The Potential of Vouacapanes from Pterodon Emarginatus Vogel against COVID-19 Cytokine Storm

Oliveira, L. D. A. R., da Silva, A. C. G., Thomaz, D. V., Brandão, F., da Conceição, E. C., Valadares, M. C., Bara, M. T. F., & Silveira, D. (2021) · Advanced Pharmaceutical Bulletin · doi:10.34172/apb.2023.016 · Cited by 6

Insights into the mechanism of natural terpenoids as NF-kB inhibitors: an overview on their anticancer potential

Jain, H., Dhingra, N., Narsinghani, T., & Sharma, R. (2016) · Experimental Oncology · doi:10.31768/2312-8852.2016.38(3):158-168 · Cited by 47

Molecular Basis of the Anti-Inflammatory Effects of Terpenoids

Heras, B. D. L., & Hortelano, S. (2009) · Inflammation & Allergy - Drug Targets · doi:10.2174/187152809787582534 · Cited by 176

Plant derived inhibitors of NF-κB

Golan‐Goldhirsh, A., & Gopas, J. (2013) · Phytochemistry Reviews · doi:10.1007/s11101-013-9293-5 · Cited by 36

Advances in studies on inhibitors of NF-κB derived from plant

Qi-la, C. (2014) · Zhongcaoyao

Naturally Occurring NF-κB Inhibitors

Nam, N. (2006) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/138955706777934937 · Cited by 440