The DOI matches its Crossref record; 261 of the 261 references it cites were found in a registry or an index.
ROS signaling and redox biology in endothelial cells
Open accessAbstract
The purpose of this review is to provide an overview of redox mechanisms, sources and antioxidants that control signaling events in ECs. In particular, we describe which molecules are involved in redox signaling and how they influence the relationship between ECs and other vascular component with regard to angiogenesis. Recent and new tools to investigate physiological ROS signaling will be also discussed. Such findings are providing an overview of the ROS biology relevant for endothelial cells in the context of normal and pathological angiogenic conditions.
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“NOX5 also appears to modulate proliferation and cell migration processes (371, 719).”
From Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation (2019) · cites this paper as [719]
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Cites
ROS function in redox signaling and oxidative stress
Schieber, M., & Chandel, N. S. (2014) · Current Biology · doi:10.1016/j.cub.2014.03.034 · Cited by 6,931
Molecular mechanisms and clinical applications of angiogenesis
Carmeliet, P., & Jain, R. K. (2011) · Nature · doi:10.1038/nature10144 · Cited by 5,467
Nitric oxide synthases: regulation and function
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Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
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Modulation of oxidative stress as an anticancer strategy
Gorrini, C., Harris, I. S., & Mak, T. W. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd4002 · Cited by 3,579
Crosstalk of reactive oxygen species and NF-κB signaling
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The complexity of NF-κB signaling in inflammation and cancer
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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
Chouchani, E. T., Pell, V. R., Gaude, E., Aksentijević, D., Sundier, S. Y., Robb, E. L., Logan, A., Nadtochiy, S. M., Ord, E. N. J., Smith, A. C., et al. (2014) · Nature · doi:10.1038/nature13909 · Cited by 2,907 · cited 1×
“The mitochondria are considered the prominent sources of endogenous ROS under physiological conditions and deregulated mitochondrial ROS production is associated to many cardiovascular alterations [99].”
BackgroundSignal transduction by reactive oxygen species
Finkel, T. (2011) · Journal of Cell Biology · doi:10.1083/jcb.201102095 · Cited by 2,322
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Hasanuzzaman, M., Bhuyan, M. H. M. B., Zulfiqar, F., Raza, A., Mohsin, S. M., Mahmud, J. A., Fujita, M., & Fotopoulos, V. (2020) · Antioxidants · doi:10.3390/antiox9080681 · Cited by 3,314
ROS homeostasis and metabolism: a dangerous liason in cancer cells
Panieri, E., & Santoro, M. M. (2016) · Cell Death and Disease · doi:10.1038/cddis.2016.105 · Cited by 1,187
Self-citationRole of oxidative stress in Alzheimer’s disease
HUANG, W.-J., ZHANG, X., & CHEN, W.-W. (2016) · Biomedical Reports · doi:10.3892/br.2016.630 · Cited by 1,023
Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation
Tejero, J., Shiva, S., & Gladwin, M. T. (2019) · Physiological Reviews · doi:10.1152/physrev.00036.2017 · Cited by 541
Neutrophil, neutrophil extracellular traps and endothelial cell dysfunction in sepsis
Zhang, H., Wang, Y., Qu, M., Li, W., Wu, D., Cata, J. P., & Miao, C. (2023) · Clinical and Translational Medicine · doi:10.1002/ctm2.1170 · Cited by 442
Metadata
- Authors
- Panieri, E., & Santoro, M. M.
- Affiliations
- University of Turin (IT)
- Vlaams Instituut voor Biotechnologie (BE)
- Corresponding author
- Santoro, Massimo M.
- Venue
- Cellular and Molecular Life Sciences
- Published
- 2015-05-14
- Volume
- 72
- Issue
- 17
- Pages
- 3281-3303
- ISSN
- 1420-682X (ISSN-L)
- 1420-9071
- PMC
- PMC11113497
- OpenAlex
- W347357337
- Cited by
- 168
- References
- 261
- Citations by year
- 2026: 21 · 2025: 10 · 2024: 9 · 2023: 17 · 2022: 13 · 2021: 17 · 2020: 15 · 2019: 15 · 2018: 14 · 2017: 14 · 2016: 20 · 2015: 2
- FWCI
- 1.61
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Cellular and Molecular Life Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Institutional Research Information System University of Turin (University of Turin) (submittedVersion)
- Padua Research Archive (University of Padova) (submittedVersion)
- Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, other-oa)
- Funders
- Fondazione Telethon (GGP10195)
- European Research Council (CoG - 647057)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Angiogenesis and VEGF in Cancer
- Keywords
- reactive oxygen species, redox signaling, endothelial cells, antioxidants, angiogenesis, oxidative stress, vascular component
- MeSH terms
- Animals, Humans, Mitochondria, Oxidation-Reduction, Signal Transduction, Protein Tyrosine Phosphatases, Reactive Oxygen Species, Neovascularization, Physiologic, NADPH Oxidases, Endothelial Cells
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