Cited by 341Microbial Metabolism and ApplicationsAlgal biology and biofuel productionMicrobial Metabolic Engineering and Bioproduction

Environmental and cultural stimulants in the production of carotenoids from microorganisms

Bhosale, P.·2004·Applied Microbiology and Biotechnology

Abstract

Commercial production of carotenoids from microorganisms competes mainly with synthetic manufacture by chemical procedures. Efficient stimulation of carotenoid biosynthesis is expected to promote accumulation of carotenoid by microbes. This review describes the variety of environmental and cultural stimulants studied during the last few decades which enhance volumetric production and cellular accumulation of commercially important carotenoids from microalgae, fungi and bacteria. Stimulation of carotenoid production by white-light illumination and temperature fluctuation is discussed along with supplementation of metal ions, salts, organic solvents, preformed precursors and several other chemicals in the culture broth. Reports on the improvements in yield are reviewed and assessed from a biotechnology point of view.

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Crossref · 10.1007/s00253-003-1441-1

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87 of 87 references verified0 citation errors · 0 not checkable

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Authors
Bhosale, P.
Affiliations
University of Utah (US)
Corresponding author
Bhosale, P.
Venue
Applied Microbiology and Biotechnology
Published
2004-01-01
Volume
63
Issue
4
Pages
351-361
ISSN
  • 0175-7598 (ISSN-L)
  • 1432-0614
OpenAlex
W2008784761
Cited by
341
References
94
Citations by year
2026: 10 · 2025: 16 · 2024: 18 · 2023: 19 · 2022: 23 · 2021: 23 · 2020: 24 · 2019: 18 · 2018: 12 · 2017: 16 · 2016: 13 · 2015: 17 · 2014: 18 · 2013: 21 · 2012: 15
FWCI
7.32
Type
journal article
Language
en
Open access
closed
Locations
  • Applied Microbiology and Biotechnology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Microbial Metabolism and Applications
  • Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
Keywords
carotenoid production, microbial carotenoids, microalgae, fungi, bacteria, white light illumination, temperature fluctuations, metal ions, organic solvents, precursors, carotenoid biosynthesis, carotenoid accumulation
MeSH terms
Bacteria, Biotechnology, Carotenoids, Culture Media, Fungi, Light, Temperature, Bioreactors, Eukaryota

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