Hypermobility prevalence, measurements, and outcomes in childhood, adolescence, and emerging adulthood: a systematic review
Open accessAbstract
General Joint Hypermobility (GJH) is a common condition found in 2–57% of the population. Of those with GJH, 10% suffer from accompanying physical and/or psychological symptoms. While the understanding of GJH in the general population is unfolding, its implication in a cohort of children, adolescents and young adults are not yet understood. This systematic review explored GJH’s prevalence, tools to measure it, its physical and psychosocial symptoms, with a special interest in aesthetic sports. The CINHAL, MEDLINE, PsycINFO, SPORTDiscus and Scopus databases were searched for relevant studies. Inclusion criteria were (1) Age range of 5–24; (2) Participants had GJH; (3) A measurement for GJH; (4) Studies written in English language. Study screening for title, abstract and full text (when needed) and quality assessment were performed by two independent individuals. 107 studies were included in this review and were thematically grouped into six clusters expressing different foci: (1) GJH’s Core Characteristics; (2) Orthopedic; (3) Physical Other; (4) Psychosocial; (5) Treatment and (6) Aesthetic Sports. The review revealed a growing interest in GJH in this cohort in the last decade, especially regarding non-musculoskeletal physical implications and psychosocial aspects. Prevalence varied between different ethnic groups and as a parameter of age, gender and measurement. The most widespread tool to measure GJH was the Beighton scale, with a cut-off varying between 4 and 7. Children show fewer, but similar GJH implication to those in the general population, however, more research on the topic is warranted, especially regarding psychosocial aspects and treatment.
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Research adopting a biopsychosocial approach is emerging, although it is still limited in this population.
“Research adopting a biopsychosocial approach is emerging, although it is still limited in this population.75,76”
From Role of Anxiety in Individuals with Generalized Joint Hypermobility: A Systematic Review (2025) · cites this paper as [75]
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Role of Anxiety in Individuals with Generalized Joint Hypermobility: A Systematic Review
van Die-de Vries, J. E., Rameckers, E., Calders, P., Engelbert, R. H., Ramaekers, S. P., Goossens, M. E., & Verbunt, J. A. (2025) · Archives of Rehabilitation Research and Clinical Translation · doi:10.1016/j.arrct.2025.100467 · Cited by 1 · see citing works
“75,76 In this review, such an approach was only applied to HSD and hEDS patients in specialized rehabilitation settings, where it is common practice to treat populations with complex disabilities.”
Postural alignment and balance characteristics in women with generalized joint hypermobility
Pilvinytė, K., Daunoravičienė, A., Gurskienė, E., & Aukštuolytė-Bačienė, E. (2026) · Journal of Complexity in Health Sciences · doi:10.21595/chs.2026.26743
“Symptomatic GJH has been reported to affect approximately 0.5 %-2 % of the general population [6].”
Influential
- Authors
- Blajwajs, L., Williams, J., Timmons, W., & Sproule, J.
- Affiliations
- University of Edinburgh (GB)
- Corresponding author
- Blajwajs, Liron
- Venue
- Rheumatology International
- Published
- 2023-05-06
- Volume
- 43
- Issue
- 8
- Pages
- 1423-1444
- ISSN
- 0172-8172 (ISSN-L)
- 1437-160X
- PMC
- PMC10261186
- OpenAlex
- W4375855661
- Cited by
- 35
- References
- 22
- Citations by year
- 2026: 15 · 2025: 15 · 2024: 5
- FWCI
- 1.35
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Rheumatology International (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, cc-by)
- Funders
- University of Edinburgh
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
- Health Sciences › Health Professions › Pharmacy › Oral and gingival health research
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Keywords
- prevalence, Beighton scale, children, adolescents, young adults, aesthetic sports, psychosocial symptoms, ethnic differences
- MeSH terms
- Adolescent, Adult, Child, Cross-Sectional Studies, Humans, Joint Instability, Physical Examination, Prevalence, Young Adult
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