Accumulation of α-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy

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Nigral and Cortical Lewy Bodies and Dystrophic Nigral Neurites in Parkinsonʼs Disease and Cortical Lewy Body Disease Contain α-synuclein Immunoreactivity

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NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease

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Hippocampal degeneration differentiates diffuse Lewy body disease (DLBD) from Alzheimer's disease

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NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation.

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Altered presynaptic protein NACP is associated with plaque formation and neurodegeneration in Alzheimer's disease.

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Corticobasal degeneration: etiopathological significance of the cytoskeletal alterations

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Immunocytochemical and ultrastructural studies of neuronal and oligodendroglial cytoplasmic inclusions in multiple system atrophy

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Immunoreactivity profile of hippocampal CA2/3 neurites in diffuse Lewy body disease

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Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer's disease

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Immunocytochemical and ultrastructural study of Lewy body-like hyaline inclusions in familial amyotrophic lateral sclerosis

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Ubiquitin-positive CA2/3 neurites in hippocampus coexist with cortical Lewy bodies

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Autosomal dominant diffuse Lewy body disease

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Hereditary dentatorubral-pallidoluysian atrophy: ubiquitinated filamentous inclusions in the cerebellar dentate nucleus neurons

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Tau immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy

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Neurofibrillary tangles in the dentate granule cells of patients with Alzheimer's disease, Lewy body disease and progressive supranuclear palsy

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Widespread multiple system degeneration in a patient with familial amyotrophic lateral sclerosis

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Neuronal inclusions in the dentate fascia in patients with multiple system atrophy

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Ultrastructural Relationship between Lewy Bodies and Pale Bodies Studied in Locus Ceruleus Neurons of a Non‐Parkinsonian Patient

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Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work.

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Alpha-synuclein and neurodegenerative diseases

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Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies

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The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration

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Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders.

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Lewy body disordersとmultiple system atrophyに共通するα-synuclein/NACPの異常蓄積

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＜Symposium III＞Pathology of neuro-glial α-synucleinopathy (Lewy body disease and multiple system atrophy)

Wakabayashi, K., Miki, Y., Tanji, K., & Mori, F. (2010) · Institutional Repositories DataBase (IRDB)