Cited by 3,836Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and SignalingAlzheimer's disease research and treatments

AlaSOPro mutation in the gene encoding α-synuclein in Parkinson's disease

Krüger, Rejko, Kuhn, Wilfried, Müller, Thomas, Woitalla, Dirk, Graeber, Manuel, Kösel, Sigfried, Przuntek, Horst, Epplen, Jörg T. +2 more·1998·Nature Genetics

Integrity signals

Registry

Crossref · 10.1038/ng0298-106

Cites

10 of 10 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • All known autosomal dominant point mutations that cause PD reside within the 11-residue repeat motifs of αSyn.

    “all known autosomal dominant point mutations that cause PD reside within these repeat motifs, specifically A30P[120], E46K[121], A53T[122], G51D[123], and H50Q[124]”

    From α-synuclein in the pathophysiology of Alzheimer’s disease (2019) · cites this paper as [120]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Krüger, R., Kuhn, W., Müller, T., Woitalla, D., Graeber, M., Kösel, S., Przuntek, H., Epplen, J. T., Schols, L., & Riess, O.
Affiliations
  • Ruhr University Bochum (DE)
  • Max Planck Society (DE)
Corresponding author
Riess, Olaf
Venue
Nature Genetics
Published
1998-02
Volume
18
Issue
2
Pages
106-108
ISSN
  • 1061-4036 (ISSN-L)
  • 1546-1718
OpenAlex
W2091265794
Cited by
3,836
References
10
Citations by year
2026: 56 · 2025: 64 · 2024: 102 · 2023: 109 · 2022: 115 · 2021: 118 · 2020: 122 · 2019: 134 · 2018: 140 · 2017: 140 · 2016: 117 · 2015: 129 · 2014: 155 · 2013: 169 · 2012: 155
FWCI
92.86
Type
journal article
Language
en
Open access
closed
Locations
  • Nature Genetics (publishedVersion)
  • PubMed (publishedVersion)
  • Open Repository and Bibliography (University of Luxembourg) (submittedVersion)
Topics
  • Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nuclear Receptors and Signaling
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
Keywords
alpha-synuclein, Parkinson's disease, synucleinopathies, protein misfolding, UBQLN2, genetic mutations
MeSH terms
Alanine, Amino Acid Sequence, Base Sequence, Female, Humans, Male, Nerve Tissue Proteins, Parkinson Disease, Pedigree, Proline, Point Mutation, Polymorphism, Single-Stranded Conformational, Synucleins, alpha-Synuclein

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review