CoChat
Sign Up
Cited by 64

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Gut microbiota as a candidate for lifespan extension: an ecological/evolutionary perspective targeted on living organisms as metaorganisms

Ottaviani, E., Ventura, N., Mandrioli, M., Candela, M., Franchini, A., Franceschi, C.·2011·Biogerontology
DOI 10.1007/s10522-011-9352-5
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1007/s10522-011-9352-5

Cites

8 of 8 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 8 references

Research works printed but not linked: 91

  1. Arumugam TV, Gleichmann M, Tang SC, Mattson MP (2006) Hormesis/preconditioning mechanisms, the nervous system and aging. Ageing Res Rev 5:165–178 · DOI
  2. Avery L, Shtonda BB (2003) Food transport in the C. elegans pharynx. J Exp Biol 206:2441–2457 · DOI
  3. Biagi E, Candela M, Fairweather-Tait S, Franceschi C, Brigidi P (2011) Aging of the human metaorganism: the microbial counterpart. Age (Dordr). doi: 10.1007/s11357-011-9217-5 · DOI
  4. Biteau B, Hochmuth CE, Jasper H (2008) JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut. Cell Stem Cell 3:442–455 · DOI · Paper page
  5. Biteau B, Karpac J, Supoyo S, Degennaro M, Lehmann R, Jasper H (2010) Lifespan extension by preserving proliferative homeostasis in Drosophila. PLoS Genet 14:e1001159 · DOI
  6. Blaser MJ, Falkow S (2009) What are the consequences of the disappearing human microbiota? Nat Rev Microbiol 7:887–894 · DOI
  7. Blaser MJ, Kirschner D (2007) The equilibria that allow bacterial persistence in human hosts. Nature 449:843–849 · DOI
  8. Brenner S (2009) In the beginning was the worm. Genetics 182:413–415 · DOI
  9. Brivio MF, Mastore M, Pagani M (2005) Parasite-host relationship: a lesson from a professional killer. Inv Surv J 2:41–53
  10. Brown KL, Hancock RE (2006) Cationic host defense (antimicrobial) peptides. Curr Opin Immunol 18:24–30 · DOI
  11. Brummel T, Ching A, Seroude L, Simon AF, Benzer S (2004) Drosophila lifespan enhancement by exogenous bacteria. Proc Natl Acad Sci USA 101:12974–12979 · DOI
  12. Buchon N, Broderick NA, Chakrabarti S, Lemaitre B (2009) Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila. Genes Dev 23:2333–2344 · DOI
  13. Calabrese EJ, Bachmann KA, Bailer AJ, Bolger PM, Borak J, Cai L, Cedergreen N, Cherian MG, Chiueh CC, Clarkson TW, Cook RR, Diamond DM, Doolittle DJ, Dorato MA, Duke SO, Feinendegen L, Gardner DE, Hart RW, Hastings KL, Hayes AW, Hoffmann GR, Ives JA, Jaworowski Z, Johnson TE, Jonas WB, Kaminski NE, Keller JG, Klaunig JE, Knudsen TB, Kozumbo WJ, Lettieri T, Liu SZ, Maisseu A, Maynard KI, Masoro EJ, McClellan RO, Mehendale HM, Mothersill C, Newlin DB, Nigg HN, Oehme FW, Phalen RF, Philbert MA, Rattan SI, Riviere JE, Rodricks J, Sapolsky RM, Scott BR, Seymour C, Sinclair DA, Smith-Sonneborn J, Snow ET, Spear L, Stevenson DE, Thomas Y, Tubiana M, Williams GM, Mattson MP (2007) Biological stress response terminology: integrating the concepts of adaptive response and preconditioning stress within a hormetic dose–response framework. Toxicol Appl Pharmacol 222:122–128 · DOI
  14. Candela M, Maccaferri S, Turroni S, Carnevali P, Brigidi P (2010) Functional intestinal microbiome, new frontiers in prebiotic design. Int J Food Microbiol 140:93–101 · DOI
  15. Candela M, Guidotti M, Fabbri A, Brigidi P, Franceschi C, Fiorentini C (2011) Human intestinal microbiota: cross-talk with the host and its potential role in colorectal cancer. Crit Rev Microbiol 37:1–14 · DOI
  16. Cevenini E, Caruso C, Candore G, Capri M, Nuzzo D, Duro G, Rizzo C, Colonna-Romano G, Lio D, Di Carlo D, Palmas MG, Scurti M, Pini E, Franceschi C, Vasto S (2010) Age-related inflammation: The contribution of different organs, tissues and systems. How to face it for therapeutic approaches. Curr Pharm Des 16:609–618 · DOI
  17. Charnley AK, Hunt J, Dillon AR (1995) The germ-free culture of desert locusts, Schistocerca gregaria. J Insect Physiol 31:477–485 · DOI
  18. Choi NH, Kim JG, Yang DJ, Kim YS, Yoo MA (2008) Age-related changes in Drosophila midgut are associated with PVF2, a PDGF/VEGF-like growth factor. Aging Cell 7:318–334 · DOI
  19. Claesson MJ, Cusack S, O’Sullivan O, Greene-Diniz R, de Weerd H, Flannery E, Marchesi JR, Falush D, Dinan T, Fitzgerald G, Stanton C, van Sinderen D, O’Connor M, Harnedy N, O’Connor K, Henry C, O’Mahony D, Fitzgerald AP, Shanahan F, Twomey C, Hill C, Ross RP, O’Toole PW (2011) Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc Natl Acad Sci USA 108(Suppl 1):4586–4591 · DOI · Paper page
  20. Collins JJ, Evason K, Kornfeld K (2006) Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans. Exp Gerontol 41:1032–1039 · DOI
  21. Cypser JR, Tedesco P, Johnson TE (2006) Hormesis and aging in Caenorhabditis elegans. Exp Gerontol 41:935–939 · DOI
  22. De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M, Poullet JB, Massart S, Collini S, Pieraccini G, Lionetti P (2010) Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci USA 107:14691–14696 · DOI · Paper page
  23. De Martinis M, Franceschi C, Monti D, Ginaldi L (2006) Inflammation markers predicting frailty and mortality in the elderly. Exp Mol Pathol 80:219–227 · DOI
  24. DeVeale B, Brummel T, Seroude L (2004) Immunity and aging: the enemy within? Aging Cell 3:195–208 · DOI
  25. Dillon RJ, Charnley AK (1996) Colonization of the guts of germ-free desert locusts, Schistocerca gregaria, by the bacterium Pantoea agglomerans. J Invertebr Pathol 67:11–14 · DOI
  26. Dillon R, Charnley K (2005) Mutualism between the desert locust Schistocerca gregaria and its gut microbiota. Res Microbiol 153:503–509 · DOI
  27. Dillon RJ, Dillon VM (2004) The gut bacteria of insects: Nonpathogenic interactions. Annu Rev Entomol 49:71–92 · DOI
  28. Dillon RJ, Vennard CT, Buckling A, Charnley AK (2005) Diversity of locust gut bacteria protects against pathogen invasion. Ecol Lett 8:1291–1298 · DOI
  29. Evans EA, Kawli T, Tan MW (2008) Pseudomonas aeruginosa suppresses host immunity by activating the DAF-2 insulin-like signalling pathway in Caenorhabditis elegans. PLoS Pathog 4:e1000175 · DOI
  30. Fang-Yen C, Avery L, Samuel AD (2009) Two size-selective mechanisms specifically trap bacteria-sized food particles in Caenorhabditis elegans. Proc Natl Acad Sci USA 106:20093–20096 · DOI
  31. Fry AJ, Rand DM (2002) Wolbachia interactions that determine Drosophila melanogaster survival. Evolution 56:1976–1981 · DOI
  32. Fuhrman LE, Goel AK, Smith J, Shianna KV, Aballay A (2009) Nucleolar proteins suppress Caenorhabditis elegans innate immunity by inhibiting p53/CEP-1. PLoS Genet 5:e1000657 · DOI
  33. Garigan D, Hsu AL, Fraser AG, Kamath RS, Ahringer J, Kenyon C (2002) Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. Genetics 161:1101–1112 · DOI · Paper page
  34. Garrett WS, Gordon JI, Glimcher LH (2010) Homeostasis and inflammation in the intestine. Cell 140:859–870 · DOI
  35. Gavini F, Cayuela C, Antoine JM, Lecoq C, Le Fabure B, Membré JM, Neut C (2001) Differences in distribution of bifidobacterial and enterobacterial species in human fecal microflora of three different (children, adults, elderly) age groups. Microb Ecol Health Dis 13:40–45 · DOI
  36. Greer EL, Brunet A (2009) Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. Aging Cell 8:113–127 · DOI
  37. Hengartner MO (1997) Genetic control of programmed cell death and aging in the nematode Caenorhabditis elegans. Exp Gerontol 32:363–374 · DOI
  38. Hodgkin J, Kuwabara PE, Corneliussen B (2000) A novel bacterial pathogen, Microbacterium nematophilum, induces morphological change in the nematode C. elegans. Curr Biol 10:1615–1618 · DOI
  39. Hooper LV, Macpherson AJ (2010) Immune adaptations that maintain homeostasis with the intestinal microbiota. Nat Rev Immunol 10:159–169 · DOI
  40. Ikeda T, Yasui C, Hoshino K, Arikawa K, Nishikawa Y (2007) Influence of lactic acid bacteria on longevity of Caenorhabditis elegans and host defense against Salmonella enterica serovar enteritidis. Appl Environ Microbiol 73:6404–6409 · DOI
  41. Irazoqui JE, Ng A, Xavier RJ, Ausubel FM (2008) Role for beta-catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions. Proc Natl Acad Sci USA 105:17469–17474 · DOI
  42. Jia W, Li H, Zhao L, Nicholson JK (2008) Gut microbiota: a potential new territory for drug targeting. Nat Rev Drug Discov 7:123–129 · DOI
  43. Komura T, Yasui C, Miyamoto H, Nishikawa Y (2010) Caenorhabditis elegans as an alternative model host for Legionella pneumophila, and protective effects of Bifidobacterium infantis. Appl Environ Microbiol 76:4105–4108 · DOI
  44. Kurz CL, Chauvet S, Andrès E, Aurouze M, Vallet I, Michel GP, Uh M, Celli J, Filloux A, De Bentzmann S, Steinmetz I, Hoffmann JA, Finlay BB, Gorvel JP, Ferrandon D, Ewbank JJ (2003) Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening. EMBO J 22:1451–1460 · DOI
  45. Labrousse A, Chauvet S, Couillault C, Kurz CL, Ewbank JJ (2000) Caenorhabditis elegans is a model host for Salmonella typhimurium. Curr Biol 10:1543–1545 · DOI
  46. Larbi A, Franceschi C, Mazzatti D, Solana R, Wikby A, Pawelec G (2008) Aging of the immune system as a prognostic factor of human longevity. Physiology 23:64–74 · DOI
  47. Laws TR, Harding SV, Smith MP, Atkins TP, Titball RW (2004) Age influences resistance of Caenorhabditis elegans to killing by pathogenic bacteria. FEMS Microbiol Lett 234:281–287 · DOI
  48. Lazzaro BP (2008) Natural selection on the Drosophila antimicrobial immune system. Curr Opin Microbiol 11:284–289 · DOI
  49. Le Bourg E, Rattan SIS (2008) Mild stress and healthy aging. Springer, Dordrecht, p 187 · DOI
  50. Lemaitre B, Hoffmann J (2007) The host defense of Drosophila melanogaster. Ann Rev Immunol 25:697–743 · DOI
  51. Lenaerts I, Walker GA, Van Hoorebeke L, Gems D, Vanfleteren JR (2008) Dietary restriction of Caenorhabditis elegans by axenic culture reflects nutritional requirement for constituents provided by metabolically active microbes. J Gerontol A Biol Sci Med Sci 63:242–252 · DOI
  52. Ley RE, Lozupone CA, Hamady M, Knight R, Gordon JI (2008) Worlds within worlds: evolution of the vertebrate gut microbiota. Nat Rev Microbiol 6:776–788 · DOI
  53. Macdonald TT, Monteleone G (2005) Immunity, inflammation, and allergy in the gut. Science 307:1920–1925 · DOI
  54. Mäkivuokko H, Tiihonen K, Tynkkynen S, Paulin L, Rautonen N (2010) The effect of age and non-steroidal anti-inflammatory drugs on human intestinal microbiota composition. Br J Nutr 103:227–234 · DOI
  55. Malagoli D, Mandrioli M (2010) Gene silencing and the analysis of immune response in model insects. In: Catalano AJ (ed) Gene silencing: theory techniques and applications. Nova Science Publishers Inc, Hauppauge, pp 167–182
  56. Mallo GV, Kurz CL, Couillault C, Pujol N, Granjeaud S, Kohara Y, Ewbank JJ (2002) Inducible antibacterial defense system in C. elegans. Curr Biol 12:1209–1214 · DOI
  57. Mandrioli M (2009) The interaction insect–symbiont, rather than insect-pathogen, may open new perspectives in the understanding of the host choice in bacteria. Inv Surv J 6:98–101
  58. Mandrioli M, Bugli S, Saltini S, Genedani S, Ottaviani E (2003) Molecular characterization of a defensin in the IZD-MB-0503 cell line derived from immunocytes of the insect Mamestra brassicae (Lepidoptera). Biol Cell 95:53–57 · DOI
  59. Maynard CL, Weaver CT (2009) Intestinal effector T cells in health and disease. Immunity 31:389–400 · DOI
  60. McFall-Ngai M (2008) Are biologists in ‘future shock’? Symbiosis integrates biology across domains. Nat Rev Microbiol 6:789–792 · DOI
  61. Min KT, Benzer S (1997) Wolbachia, normally a symbiont of Drosophila, can be virulent, causing degeneration and early-death. Proc Natl Acad Sci USA 94:10792–10796 · DOI
  62. Müller S, Saunier K, Hanisch C, Norin E, Alm L, Midtvedt T, Cresci A, Silvi S, Orpianesi C, Verdenelli MC, Clavel T, Koebnick C, Zunft HJF, Doré J, Blaut M (2006) Differences in fecal microbiota in different European study populations in relation to age, gender, and country: A cross-sectional study. Appl Environ Microbiol 72:1027–1033 · DOI · Paper page
  63. Müller U, Vogel P, Alber G, Schaub GA (2008) The innate immune system of mammals and insects. Contrib Microbiol 15:21–44
  64. Naidu AS, Bidlack WR, Clemens RA (1999) Probiotic spectra of lactic acid bacteria (LAB). Crit Rev Food Sci Nutr 39:13–126 · DOI
  65. Neish AS (2009) Microbes in gastrointestinal health and disease. Gastroenterology 136:65–80 · DOI
  66. Noverr MC, Huffnagle GB (2004) Does the microbiota regulate immune responses outside the gut? Trends Microbiol 12:562–568 · DOI
  67. Ostan R, Bucci L, Capri M, Salvioli S, Scurti M, Pini E, Monti D, Franceschi C (2008) Immunosenescence and immunogenetics of human longevity. Neuroimmunomodulation 15:224–240 · DOI
  68. Rajilić-Stojanović M, Smidt H, de Vos WM (2007) Diversity of the human gastrointestinal tract microbiota revisited. Environ Microbiol 9:2125–2136 · DOI · Paper page
  69. Rajilić-Stojanović M, Heilig HG, Molenaar D, Kajander K, Surakka A, Smidt H, de Vos WM (2009) Development and application of the Human Intestinal Tract Chip, a phylogenetic microarray: Analysis of the universally conserved phylotypes in the abundant microbiota of young and elderly adults. Environ Microbiol 11:1736–1751 · DOI · Paper page
  70. Rankin CH (2006) Nematode behavior: the taste of success, the smell of danger!. Curr Biol 16:R89–R91 · DOI
  71. Rattan SI (2008) Hormesis in aging. Ageing Res Rev 7:63–78 · DOI · Paper page
  72. Rawls JF (2007) Enteric infection and inflammation alter gut microbial ecology. Cell Host Microbe 2:73–74 · DOI
  73. Reinke SN, Hu X, Sykes BD, Lemire BD (2010) Caenorhabditis elegans diet significantly affects metabolic profile, mitochondrial DNA levels, lifespan and brood size. Mol Genet Metab 100:274–282 · DOI
  74. Round JL, Mazmanian SK (2009) The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 9:313–323 · DOI · Paper page
  75. Ryu JH, Kim SH, Lee HY, Bai JY, Nam YD, Bae JW, Lee DG, Shin SC, Ha EM, Lee WJ (2008) Innate immune homeostasis by the homeobox gene Caudal and commensal-gut mutualism in Drosophila. Science 319:777–782 · DOI
  76. Saiki R, Lunceford AL, Bixler T, Dang P, Lee W, Furukawa S, Larsen PL, Clarke CF (2008) Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q. Aging Cell 7:291–304 · DOI
  77. Sansonetti PJ (2011) To be or not to be a pathogen: that is the mucosally relevant question. Mucosal Immunol 4:8–14 · DOI
  78. Sansonetti PJ, Medzhitov R (2009) Learning tolerance while fighting ignorance. Cell 138:416–420 · DOI
  79. Schmidt O, Rahman MM, Ma G, Theopold U, Sun Y, Sarjan M, Fabbri M, Roberts H (2005) Mode of action of antimicrobial proteins, pore-forming toxins and biologically active peptides (hypothesis). Inv Surv J 2:82–90
  80. Shivers RP, Youngman MJ, Kim DH (2008) Transcriptional responses to pathogens in Caenorhabditis elegans. Curr Opin Microbiol 11:251–256 · DOI
  81. Shtonda BB, Avery L (2006) Dietary choice behavior in Caenorhabditis elegans. J Exp Biol 209:89–102 · DOI
  82. Star DJ, Cline TW (2002) Host parasite interaction rescues Drosophila oogenesis defects. Nature 418:76–79 · DOI
  83. Tan MW, Rahme LG, Sternberg JA, Tompkins RG, Ausubel FM (1999) Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Proc Natl Acad Sci USA 96:2408–2413 · DOI
  84. Turnbaugh PJ, Ley RE, Hamady M, Fraser-Liggett CM, Knight R, Gordon JI (2007) The human microbiome project. Nature 449:804–810 · DOI · Paper page
  85. Turnbaugh PJ, Hamady M, Yatsunenko T, Cantarel BL, Duncan A, Ley RE, Sogin ML, Jones WJ, Roe BA, Affourtit JP, Egholm M, Henrissat B, Heath AC, Knight R, Gordon JI (2009) A core gut microbiome in obese and lean twins. Nature 457:480–484 · DOI · Paper page
  86. Turnbaugh PJ, Quince C, Faith JJ, McHardy AC, Yatsunenko T, Niazi F, Affourtit J, Egholm M, Henrissat B, Knight R, Gordon JI (2010) Organismal, genetic, and transcriptional variation in the deeply sequenced gut microbiomes of identical twins. Proc Natl Acad Sci USA 107:7503–7508 · DOI · Paper page
  87. Ventura N, Rea SL, Schiavi A, Torgovnick A, Testi R, Johnson TE (2009) p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress. Aging Cell 8:380–393 · DOI
  88. Weksler ME, Pawelec G, Franceschi C (2009) Immune therapy for age-related diseases. Trends Immunol 30:344–350 · DOI
  89. Woodmansey EJ, McMurdo ME, Macfarlane GT, Macfarlane S (2004) Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic treated elderly subjects. Appl Environ Microbiol 70:6113–6122 · DOI · Paper page
  90. Yang YY, Gangoiti JA, Sedensky MM, Morgan PG (2009) The effect of different ubiquinones on lifespan in Caenorhabditis elegans. Mech Ageing Dev 130:370–376 · DOI
  91. Zhang X, Zhang Y (2009) Neural-immune communication in Caenorhabditis elegans. Cell Host Microbe 5:425–429 · DOI

Cited by

Sorted by citations

Metadata

Authors
Ottaviani, E., Ventura, N., Mandrioli, M., Candela, M., Franchini, A., & Franceschi, C.
Venue
Biogerontology
Publisher
Springer Science and Business Media LLC
Published
2011-08-04
Volume
12
Issue
6
Pages
599-609
ISSN
  • 1389-5729
  • 1573-6768
DOI
10.1007/s10522-011-9352-5
Cited by
64
References
8
Language
en
Licence
www.springer.com/tdm (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review