Diet, gut microbiota and immune responses

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

De Filippo, C., Cavalieri, D., Di Paola, M., Ramazzotti, M., Poullet, J. B., Massart, S., Collini, S., Pieraccini, G., & Lionetti, P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005963107 · Cited by 5,579 · see citing works

Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

Frank, D. N., St. Amand, A. L., Feldman, R. A., Boedeker, E. C., Harpaz, N., & Pace, N. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706625104 · Cited by 4,611 · see citing works

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

Maslowski, K. M., Vieira, A. T., Ng, A., Kranich, J., Sierro, F., Yu, D., Schilter, H. C., Rolph, M. S., Mackay, F., Artis, D., et al. (2009) · Nature · doi:10.1038/nature08530 · Cited by 3,241 · see citing works

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

Oh, D. Y., Talukdar, S., Bae, E. J., Imamura, T., Morinaga, H., Fan, W., Li, P., Lu, W. J., Watkins, S. M., & Olefsky, J. M. (2010) · Cell · doi:10.1016/j.cell.2010.07.041 · Cited by 2,428 · see citing works

Inducible Foxp3 ⁺ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

Round, J. L., & Mazmanian, S. K. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909122107 · Cited by 2,233 · see citing works

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

Vijay-Kumar, M., Aitken, J. D., Carvalho, F. A., Cullender, T. C., Mwangi, S., Srinivasan, S., Sitaraman, S. V., Knight, R., Ley, R. E., & Gewirtz, A. T. (2010) · Science · doi:10.1126/science.1179721 · Cited by 2,068 · see citing works

Omega-3 Fatty Acids in Inflammation and Autoimmune Diseases

Simopoulos, A. P. (2002) · Journal of the American College of Nutrition · doi:10.1080/07315724.2002.10719248 · Cited by 2,014 · see citing works

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

Wen, L., Ley, R. E., Volchkov, P. Y., Stranges, P. B., Avanesyan, L., Stonebraker, A. C., Hu, C., Wong, F. S., Szot, G. L., Bluestone, J. A., et al. (2008) · Nature · doi:10.1038/nature07336 · Cited by 1,921 · see citing works

Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study

Patterson, C. C., Dahlquist, G. G., Gyürüs, E., Green, A., & Soltész, G. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60568-7 · Cited by 1,854 · see citing works

Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation

Le Poul, E., Loison, C., Struyf, S., Springael, J.-Y., Lannoy, V., Decobecq, M.-E., Brezillon, S., Dupriez, V., Vassart, G., Van Damme, J., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301403200 · Cited by 1,651 · see citing works

Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

Wu, H.-J., Ivanov, I. I., Darce, J., Hattori, K., Shima, T., Umesaki, Y., Littman, D. R., Benoist, C., & Mathis, D. (2010) · Immunity · doi:10.1016/j.immuni.2010.06.001 · Cited by 1,577 · see citing works

Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing

Kalliomäki, M., Kirjavainen, P., Eerola, E., Kero, P., Salminen, S., & Isolauri, E. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.111237 · Cited by 1,255 · see citing works

Family size, infection and atopy: the first decade of the 'hygiene hypothesis'

Strachan, D. (2000) · Thorax · doi:10.1136/thorax.55.suppl_1.s2 · Cited by 1,183 · see citing works

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

Clarke, T. B., Davis, K. M., Lysenko, E. S., Zhou, A. Y., Yu, Y., & Weiser, J. N. (2010) · Nature Medicine · doi:10.1038/nm.2087 · Cited by 1,154 · see citing works

Reduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces

Duncan, S. H., Belenguer, A., Holtrop, G., Johnstone, A. M., Flint, H. J., & Lobley, G. E. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.02340-06 · Cited by 941 · see citing works

Changes in the Composition of the Human Fecal Microbiome After Bacteriotherapy for Recurrent Clostridium difficile-associated Diarrhea

Khoruts, A., Dicksved, J., Jansson, J. K., & Sadowsky, M. J. (2010) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e3181c87e02 · Cited by 649 · see citing works

Why whole grains are protective: biological mechanisms

Slavin, J. L. (2003) · Proceedings of The Nutrition Society · doi:10.1079/pns2002221 · Cited by 614 · see citing works

Does the microbiota regulate immune responses outside the gut?

Noverr, M. C., & Huffnagle, G. B. (2004) · Trends in Microbiology · doi:10.1016/j.tim.2004.10.008 · Cited by 499 · see citing works

Fecal microbiota in early rheumatoid arthritis.

Vaahtovuo, J., Munukka, E., Korkeamäki, M., Luukkainen, R., & Toivanen, P. (2008) · PubMed · Cited by 426 · see citing works

The increase in the prevalence of asthma and allergy: food for thought

Devereux, G. S. (2006) · Nature reviews. Immunology · doi:10.1038/nri1958 · Cited by 309 · see citing works

Fasting followed by vegetarian diet in patients with rheumatoid arthritis: a systematic review

Müller, F. (2001) · Scandinavian Journal of Rheumatology · doi:10.1080/030097401750065256 · Cited by 285 · see citing works

Low Maternal Vitamin E Intake during Pregnancy Is Associated with Asthma in 5-Year-Old Children

Devereux, G. S., Turner, S. W., Craig, L. C. A., McNeill, G., Martindale, S., Harbour, P. J., Helms, P. J. B., & Seaton, A. (2006) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200512-1946oc · Cited by 268 · see citing works

Short-Chain Fatty Acids in Germfree Mice and Rats

Høverstad, T., & Midtvedt, T. (1986) · Journal of Nutrition · doi:10.1093/jn/116.9.1772 · Cited by 256 · see citing works

Effects of dietary fiber on inflammatory bowel disease

Gálvez, J., Rodríguez‐Cabezas, M. E., & Zarzuelo, A. (2005) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200500013 · Cited by 231 · see citing works

Regulation at multiple levels of NF-κB-mediated transactivation by protein acetylation

Quivy, V., & Lint, C. M. V. (2004) · Biochemical Pharmacology · doi:10.1016/j.bcp.2004.05.039 · Cited by 219 · see citing works

Obesity and the lung: 4 {middle dot} Obesity and asthma

Sin, D. D., & Sutherland, E. R. (2008) · Thorax · doi:10.1136/thx.2007.086819 · Cited by 149 · see citing works

Influence of microbial environment on autoimmunity

Chervonsky, A. V. (2009) · Nature Immunology · doi:10.1038/ni.1801 · Cited by 147 · see citing works

INTESTINAL FLORA IN EARLY RHEUMATOID ARTHRITIS

Eerola, E., Möttönen, T. T., Hannonen, P., Luukkainen, R., Kantola, I. M., Vuori, K., Tuominen, J., & Toivanen, P. (1994) · Lara D. Veeken · doi:10.1093/rheumatology/33.11.1030 · Cited by 90 · see citing works

Phagocytosis, peritoneal influx, and enzyme activities in peritoneal macrophages from germfree, conventional, and ex-germfree mice

Mørland, B., & Midtvedt, T. (1984) · Infection and Immunity · doi:10.1128/iai.44.3.750-752.1984 · Cited by 39 · see citing works

Gut microbiota, metabolites and host immunity

Rooks, M. G., & Garrett, W. S. (2016) · Nature reviews. Immunology · doi:10.1038/nri.2016.42 · Cited by 3,409 · see citing works

Gut Microbiota Metabolism of Dietary Fiber Influences Allergic Airway Disease and Hematopoiesis

Trompette, A., Gollwitzer, E. S., Yadava, K., Sichelstiel, A. K., Sprenger, N., Ngom-Bru, C., Blanchard, C., Junt, T., Nicod, L. P., Harris, N. L., et al. (2014) · Nature Medicine · doi:10.1038/nm.3444 · Cited by 2,862 · see citing works

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

Atarashi, K., Tanoue, T., Oshima, K., Suda, W., Nagano, Y., Nishikawa, H., Fukuda, S., Saito, T., Narushima, S., Hase, K., et al. (2013) · Nature · doi:10.1038/nature12331 · Cited by 2,872 · see citing works

The role of short chain fatty acids in health and disease

Tan, J., McKenzie, C., Potamitis, M., Thorburn, A. N., Mackay, C. R., & Macia, L. (2014) · Advances in immunology · doi:10.1016/b978-0-12-800100-4.00003-9 · Cited by 2,425 · see citing works

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice

Devkota, S., Wang, Y., Musch, M. W., Leone, V., Fehlner-Peach, H., Nadimpalli, A., Antonopoulos, D. A., Jabri, B., & Chang, E. B. (2012) · Nature · doi:10.1038/nature11225 · Cited by 1,904 · see citing works

Intestinal homeostasis and its breakdown in inflammatory bowel disease

Maloy, K., & Powrie, F. (2011) · Nature · doi:10.1038/nature10208 · Cited by 1,865 · see citing works

Evolution of the immune system in humans from infancy to old age

Simon, A. K., Hollander, G. A., & McMichael, A. (2015) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2014.3085 · Cited by 1,796 · see citing works

The cellular and signaling networks linking the immune system and metabolism in disease

Osborn, O., & Olefsky, J. M. (2012) · Nature Medicine · doi:10.1038/nm.2627 · Cited by 1,551 · see citing works

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

Macia, L., Tan, J., Vieira, A. T., Leach, K., Stanley, D., Luong, S., Maruya, M., Ian McKenzie, C., Hijikata, A., Wong, C., et al. (2015) · Nature Communications · doi:10.1038/ncomms7734 · Cited by 1,439 · see citing works

Colonic bacterial composition in Parkinson's disease

Keshavarzian, A., Green, S. J., Engen, P. A., Voigt, R. M., Naqib, A., Forsyth, C. B., Mutlu, E., & Shannon, K. M. (2015) · Movement Disorders · doi:10.1002/mds.26307 · Cited by 1,281 · see citing works

Oral Biofilms: Pathogens, Matrix, and Polymicrobial Interactions in Microenvironments

Bowen, W. H., Burne, R. A., Wu, H., & Koo, H. (2018) · Trends in Microbiology · doi:10.1016/j.tim.2017.09.008 · Cited by 1,059 · see citing works

Plant-derived exosomal MicroRNAs shape the gut microbiota

Teng, Y., Ren, Y., Sayed, M., Hu, X., Lei, C., Kumar, A., Hutchins, E., Mu, J., Deng, Z., Luo, C., et al. (2018) · Cell Host & Microbe · doi:10.1016/j.chom.2018.10.001 · Cited by 1,027 · see citing works

The Antimicrobial Resistance Crisis: Causes, Consequences, and Management

Michael, C. A., Dominey‐Howes, D., & Labbate, M. (2014) · Frontiers in Public Health · doi:10.3389/fpubh.2014.00145 · Cited by 978 · see citing works

Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites

Thorburn, A. N., McKenzie, C. I., Shen, S., Stanley, D., Macia, L., Mason, L. J., Roberts, L. K., Wong, C. H. Y., Shim, R., Robert, R., et al. (2015) · Nature Communications · doi:10.1038/ncomms8320 · Cited by 912 · see citing works

Diet, metabolites, and “western-lifestyle” inflammatory diseases

Thorburn, A. N., Macia, L., & Mackay, C. R. (2014) · Immunity · doi:10.1016/j.immuni.2014.05.014 · Cited by 879 · see citing works

Resistant Starch: Promise for Improving Human Health

Birt, D. F., Boylston, T. D., Hendrich, S., Jane, J., Hollis, J., Li, L., McClelland, J. F., Moore, S. A., Phillips, G. J., Rowling, M. J., et al. (2013) · Advances in Nutrition · doi:10.3945/an.113.004325 · Cited by 878 · see citing works

The microbiome in infectious disease and inflammation

Honda, K., & Littman, D. R. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-074937 · Cited by 791 · see citing works

Teleost microbiomes: the state of the art in their characterization, manipulation and importance in aquaculture and fisheries

Llewellyn, M. S., Boutin, S., Hoseinifar, S. H., & Derôme, N. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00207 · Cited by 742 · see citing works

Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

Mariño, E., Richards, J. L., McLeod, K. H., Stanley, D., Yap, Y. A., Knight, J., McKenzie, C., Kranich, J., Oliveira, A. C., Rossello, F. J., et al. (2017) · Nature Immunology · doi:10.1038/ni.3713 · Cited by 686 · see citing works

Nutrients, foods, and colorectal cancer prevention

Song, M., Garrett, W. S., & Chan, A. T. (2015) · Gastroenterology · doi:10.1053/j.gastro.2014.12.035 · Cited by 700 · see citing works

Environmental risk factors for type 1 diabetes

Rewers, M., & Ludvigsson, J. (2016) · The Lancet · doi:10.1016/s0140-6736(16)30507-4 · Cited by 676 · see citing works

Gut microbiome and aging: physiological and mechanistic insights

Nagpal, R., Mainali, R., Ahmadi, S., Wang, S., Singh, R., Kavanagh, K., Kitzman, D. W., Kushugulova, A., Marotta, F., & Yadav, H. (2018) · Nutrition and Healthy Aging · doi:10.3233/nha-170030 · Cited by 670 · see citing works

Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways

Tan, J., McKenzie, C. I., Vuillermin, P., Goverse, G., Vinuesa, C. G., Mebius, R. E., Macia, L., & Mackay, C. R. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.05.047 · Cited by 666 · see citing works

Fruits, vegetables, and health: A comprehensive narrative, umbrella review of the science and recommendations for enhanced public policy to improve intake

Wallace, T. C., Bailey, R. L., Blumberg, J. B., Burton-Freeman, B., Chen, C.-Y. O., Crowe-White, K. M., Drewnowski, A., Hooshmand, S., Johnson, E., Lewis, R., et al. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1632258 · Cited by 638 · see citing works

A Prospective Study of Long-term Intake of Dietary Fiber and Risk of Crohn's Disease and Ulcerative Colitis

Ananthakrishnan, A. N., Khalili, H., Konijeti, G. G., Higuchi, L. M., de Silva, P. S., Korzenik, J. R., Fuchs, C. S., Willett, W. C., Richter, J. M., & Chan, A. T. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.07.050 · Cited by 633 · see citing works

Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice

Li, J., Sung, C. Y. J., Lee, N. P. Y., Ni, Y., Pihlajamäki, J., Panagiotou, G., & El-Nezami, H. S. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1518189113 · Cited by 624 · see citing works

Individual diet has sex-dependent effects on vertebrate gut microbiota

Bolnick, D. I., Snowberg, L. K., Hirsch, P. E., Lauber, C. L., Org, E., Parks, B. W., Lusis, A. J., Knight, R. D., Caporaso, J. G., & Svanbäck, R. (2014) · Nature Communications · doi:10.1038/ncomms5500 · Cited by 598 · see citing works

The Gut Microbiota in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease

Zuo, T., & Ng, S. C. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02247 · Cited by 590 · see citing works

The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer

Kaczmarczyk, M. M., Miller, M. J., & Freund, G. G. (2012) · Metabolism · doi:10.1016/j.metabol.2012.01.017 · Cited by 554 · see citing works

The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors

Alexander, S. P. H., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Spedding, M., Peters, J. A., Harmar, A. J., & Collaborators, C. (2013) · British Journal of Pharmacology · doi:10.1111/bph.12445 · Cited by 555 · see citing works

Midgut Microbiota of the Malaria Mosquito Vector Anopheles gambiae and Interactions with Plasmodium falciparum Infection

Boissière, A., Tchioffo, M. T., Bachar, D., Abate, L., Marié, A., Nsango, S. E., Shahbazkia, H. R., Awono‐Ambene, P., Levashina, E. A., Christen, R., et al. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002742 · Cited by 536 · see citing works

A Comprehensive Review on the Role of the Gut Microbiome in Human Neurological Disorders

Sorboni, S. G., Moghaddam, H. S., Jafarzadeh-Esfehani, R., & Soleimanpour, S. (2022) · Clinical Microbiology Reviews · doi:10.1128/cmr.00338-20 · Cited by 562 · see citing works

Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity

Wang, X., Zhang, P., & Zhang, X. (2021) · Molecules · doi:10.3390/molecules26196076 · Cited by 529 · see citing works

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

Haberman, Y., Tickle, T. L., Dexheimer, P. J., Kim, M., Tang, D., Karns, R. A., Baldassano, R. N., Noe, J. D., Rosh, J. R., Markowitz, J. F., et al. (2014) · Journal of Clinical Investigation · doi:10.1172/jci75436 · Cited by 523 · see citing works

Gut microbiome in health and disease: Linking the microbiome–gut–brain axis and environmental factors in the pathogenesis of systemic and neurodegenerative diseases

Ghaisas, S., Maher, J. M., & Kanthasamy, A. G. (2015) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2015.11.012 · Cited by 519 · see citing works

Analysis of Gut Microbiota in Patients with Parkinson’s Disease

Petrov, V. A., Saltykova, I. V., Zhukova, I. A., Alifirova, V. M., Zhukova, N. G., Dorofeeva, Y. B., Tyakht, A. V., Kovarsky, B. A., Alekseev, D. G., Kostryukova, E. S., et al. (2017) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-017-3700-7 · Cited by 487 · see citing works

High levels of butyrate and propionate in early life are associated with protection against atopy

Roduit, C., Frei, R., Ferstl, R., Loeliger, S., Westermann, P., Rhyner, C., Schiavi, E., Barcik, W., Rodríguez‐Pérez, N., Wawrzyniak, M., et al. (2018) · Allergy · doi:10.1111/all.13660 · Cited by 519 · see citing works

The impact of perinatal immune development on mucosal homeostasis and chronic inflammation

Renz, H., Brandtzæg, P., & Hornef, M. W. (2011) · Nature reviews. Immunology · doi:10.1038/nri3112 · Cited by 508 · see citing works

Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer

Coutzac, C., Jouniaux, J.-M., Paci, A., Schmidt, J., Mallardo, D., Seck, A., Asvatourian, V., Cassard, L., Saulnier, P., Lacroix, L., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16079-x · Cited by 513 · see citing works

The intestinal microbiota, a leaky gut, and abnormal immunity in kidney disease

Anders, H., Andersen, K., & Stecher, B. (2013) · Kidney International · doi:10.1038/ki.2012.440 · Cited by 495 · see citing works

The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces

Statovci, D., Aguilera, M., MacSharry, J. A., & Melgar, S. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00838 · Cited by 490 · see citing works

Phage-guided modulation of the gut microbiota of mouse models of colorectal cancer augments their responses to chemotherapy

Zheng, D., Dong, X., Pan, P., Chen, K.-W., Fan, J., Cheng, S., & Zhang, X. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0423-2 · Cited by 483 · see citing works

High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity

Schulz, M. D., Atay, Ç., Heringer, J., Romrig, F., Schwitalla, S., Aydın, B., Ziegler, P. K., Varga, J., Reindl, W., Pommerenke, C., et al. (2014) · Nature · doi:10.1038/nature13398 · Cited by 452 · see citing works

High-Glucose or -Fructose Diet Cause Changes of the Gut Microbiota and Metabolic Disorders in Mice without Body Weight Change

Do, M. H., Lee, E., Oh, M.-J., Kim, Y., & Park, H.-Y. (2018) · Nutrients · doi:10.3390/nu10060761 · Cited by 441 · see citing works

The intestinal microbiota contributes to the ability of helminths to modulate allergic inflammation

Zaiss, M. M., Rapin, A., Lebon, L., Dubey, L. K., Mosconi, I., Sarter, K., Piersigilli, A., Menin, L., Walker, A. W., Rougemont, J., et al. (2015) · Immunity · doi:10.1016/j.immuni.2015.09.012 · Cited by 437 · see citing works

The biodiversity hypothesis and allergic disease: world allergy organization position statement

Haahtela, T., Holgate, S., Pawankar, R., Akdis, C. A., Benjaponpitak, S., Caraballo, L., Demain, J., Portnoy, J., & von Hertzen, L. (2013) · World Allergy Organization Journal · doi:10.1186/1939-4551-6-3 · Cited by 426 · see citing works

Major phenylpropanoid‐derived metabolites in the human gut can arise from microbial fermentation of protein

Russell, W. R., Duncan, S. H., Scobbie, L., Duncan, G., Cantlay, L., Calder, A. G., Anderson, S. E., & Flint, H. J. (2013) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201200594 · Cited by 417 · see citing works

A Consideration of Biomarkers to be Used for Evaluation of Inflammation in Human Nutritional Studies

Calder, P. C., Ahluwalia, N., Albers, R., Bosco, N., Bourdet-Sicard, R., Haller, D., Holgate, S. T., Jönsson, L. S., Latulippe, M. E., Marcos, A., et al. (2013) · British Journal of Nutrition · doi:10.1017/s0007114512005119 · Cited by 425 · see citing works

Faecalibacterium prausnitzii subspecies-level dysbiosis in the human gut microbiome underlying atopic dermatitis

Song, H., Yoo, Y., Hwang, J., Na, Y.-C., & Kim, H. S. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2015.08.021 · Cited by 416 · see citing works

Immune Dysfunction and Risk of Infection in Chronic Kidney Disease

Syed-Ahmed, M., & Narayanan, M. (2019) · Advances in Chronic Kidney Disease · doi:10.1053/j.ackd.2019.01.004 · Cited by 420 · see citing works

Diet, Microbiota and Gut-Lung Connection

Anand, S., & Mande, S. S. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02147 · Cited by 409 · see citing works

The role of the immune system in governing host-microbe interactions in the intestine

Brown, E., Sadarangani, M., & Finlay, B. B. (2013) · Nature Immunology · doi:10.1038/ni.2611 · Cited by 403 · see citing works

Beyond gut feelings: how the gut microbiota regulates blood pressure

Marques, F. Z., Mackay, C. R., & Kaye, D. M. (2017) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2017.120 · Cited by 400 · see citing works

Role of microbiota-derived short-chain fatty acids in nervous system disorders

Mirzaei, R., Bouzari, B., Hosseini‐Fard, S. R., Mazaheri, M., Ahmadyousefi, Y., Abdi, M., Jalalifar, S., Karimitabar, Z., Teimoori, A., Keyvani, H., et al. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111661 · Cited by 400 · see citing works

Association of ultra-processed food intake with risk of inflammatory bowel disease: prospective cohort study

Narula, N., Wong, E. C. L., Dehghan, M., Mente, A., Rangarajan, S., Lanas, F. T., López-Jaramillo, P. A., Rohatgi, P., Lakshmi, P. V. M., Varma, R. P., et al. (2021) · BMJ · doi:10.1136/bmj.n1554 · Cited by 372 · see citing works

The impact of the gut microbiome on extra-intestinal autoimmune diseases

Miyauchi, E., Shimokawa, C., Steimle, A., Desai, M. S., & Ohno, H. (2022) · Nature reviews. Immunology · doi:10.1038/s41577-022-00727-y · Cited by 375 · see citing works

The gut microbiome and diet in psychiatry: focus on depression

Dash, S., Clarke, G., Berk, M., & Jacka, F. N. (2015) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000117 · Cited by 369 · see citing works

Sustainable aquaculture requires environmental‐friendly treatment strategies for fish diseases

Lieke, T., Meinelt, T., Hoseinifar, S. H., Pan, B., Straus, D. L., & Steinberg, C. E. W. (2019) · Reviews in Aquaculture · doi:10.1111/raq.12365 · Cited by 364 · see citing works

Effect of Breast and Formula Feeding on Gut Microbiota Shaping in Newborns

Guaraldi, F., & Salvatori, G. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00094 · Cited by 365 · see citing works

Interactions between Intestinal Microbiota and Host Immune Response in Inflammatory Bowel Disease

Zhang, M., Sun, K., Wu, Y., Yang, Y., Tso, P., & Wu, Z. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00942 · Cited by 347 · see citing works

Dietary input of microbes and host genetic variation shape among-population differences in stickleback gut microbiota

Smith, C. C. R., Snowberg, L. K., Caporaso, J. G., Knight, R. D., & Bolnick, D. I. (2015) · The ISME Journal · doi:10.1038/ismej.2015.64 · Cited by 359 · see citing works

Thyroid-Gut-Axis: How Does the Microbiota Influence Thyroid Function?

Knežević, J., Starchl, C., Tmava‐Berisha, A., & Amrein, K. (2020) · Nutrients · doi:10.3390/nu12061769 · Cited by 368 · see citing works

Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production

Sencio, V., Barthélémy, A., Tavares, L. P., Machado, M. G., Soulard, D., Cuinat, C., Queiroz‐Junior, C. M., Noordine, M.-L., Salomé‐Desnoulez, S., Deryuter, L., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.02.013 · Cited by 355 · see citing works

Dietary fucoidan modulates the gut microbiota in mice by increasing the abundance of Lactobacillus and Ruminococcaceae

Shang, Q., Shan, X., Cai, C., Hao, J., Li, G., & Yu, G. (2016) · Food & Function · doi:10.1039/c6fo00309e · Cited by 359 · see citing works

Microbiome-Gut-Brain Axis and Toll-Like Receptors in Parkinson’s Disease

Caputi, V., & Giron, M. C. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19061689 · Cited by 338 · see citing works

Exploring the Human Microbiome: The Potential Future Role of Next-Generation Sequencing in Disease Diagnosis and Treatment

Malla, M. A., Dubey, A., Kumar, A., Yadav, S., Hashem, A., & Allah, E. F. A. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02868 · Cited by 350 · see citing works

Evidence for the Gut Microbiota Short-Chain Fatty Acids as Key Pathophysiological Molecules Improving Diabetes

Puddu, A., Sanguineti, R., Montecucco, F., & Viviani, G. L. (2014) · Mediators of Inflammation · doi:10.1155/2014/162021 · Cited by 350 · see citing works

Breast milk, microbiota, and intestinal immune homeostasis

Walker, W. A., & Iyengar, S. R. (2014) · Pediatric Research · doi:10.1038/pr.2014.160 · Cited by 335 · see citing works

Triggers and drivers of autoimmunity: lessons from coeliac disease

Sollid, L. M., & Jabrì, B. (2013) · Nature reviews. Immunology · doi:10.1038/nri3407 · Cited by 343 · see citing works

Intestinal Dysbiosis and Rheumatoid Arthritis: A Link between Gut Microbiota and the Pathogenesis of Rheumatoid Arthritis

Horta‐Baas, G., Romero-Figueroa, M. D. S., Montiel-Jarquín, Á. J., Pizano-Zárate, M. L., Garcı́a-Mena, J., & Ramírez‐Durán, N. (2017) · Journal of Immunology Research · doi:10.1155/2017/4835189 · Cited by 328 · see citing works

The Role of the Immune System in Metabolic Health and Disease

Zmora, N., Bashiardes, S., Levy, M., & Elinav, E. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.02.006 · Cited by 323 · see citing works

Dietary modulation of the microbiome affects autoinflammatory disease

Lukens, J. R., Gurung, P., Vogel, P., Johnson, G. R., Carter, R. A., McGoldrick, D. J., Bandi, S. R., Calabrese, C. R., Walle, L. V., Lamkanfi, M., et al. (2014) · Nature · doi:10.1038/nature13788 · Cited by 314 · see citing works

The lung–gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes

Sencio, V., Machado, M. G., & Trottein, F. (2021) · Mucosal Immunology · doi:10.1038/s41385-020-00361-8 · Cited by 315 · see citing works

Role of reactive oxygen and nitrogen species in the vascular responses to inflammation

Kvietys, P. R., & Granger, D. N. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.11.002 · Cited by 313 · see citing works

The Human Microbiome and Its Potential Importance to Pediatrics

Johnson, C. L., & Versalovic, J. A. (2012) · PEDIATRICS · doi:10.1542/peds.2011-2736 · Cited by 310 · see citing works

Metabolic benefits of dietary prebiotics in human subjects: a systematic review of randomised controlled trials

Kellow, N. J., Coughlan, M. T., & Reid, C. M. (2014) · British Journal of Nutrition · doi:10.1017/s0007114513003607 · Cited by 307 · see citing works

World Gastroenterology Organisation Global Guidelines

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Cultured Cordyceps sinensis polysaccharides modulate intestinal mucosal immunity and gut microbiota in cyclophosphamide-treated mice

Ying, M., Yu, Q., Zheng, B., Wang, H., Wang, J., Chen, S., Nie, S., & Xie, M. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.115957 · Cited by 305 · see citing works

Metabolite-Sensing G Protein–Coupled Receptors—Facilitators of Diet-Related Immune Regulation

Tan, J. K., McKenzie, C. I., Mariño, E., Macia, L., & Mackay, C. R. (2017) · Annual Review of Immunology · doi:10.1146/annurev-immunol-051116-052235 · Cited by 303 · see citing works

Probiotic Cell‐Free Supernatants Exhibited Anti‐Inflammatory and Antioxidant Activity on Human Gut Epithelial Cells and Macrophages Stimulated with LPS

De Marco, S., Sichetti, M., Muradyan, D., Piccioni, M., Traina, G., Pagiotti, R., & Pietrella, D. (2018) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2018/1756308 · Cited by 297 · see citing works

Alterations in Intestinal Microbiota Correlate With Susceptibility to Type 1 Diabetes

Alkanani, A. K., Hara, N., Gottlieb, P. A., Ir, D., Robertson, C. E., Wagner, B. D., Frank, D. N., & Zipris, D. (2015) · Diabetes · doi:10.2337/db14-1847 · Cited by 287 · see citing works

Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells

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Lactate and short chain fatty acids produced by microbial fermentation downregulate proinflammatory responses in intestinal epithelial cells and myeloid cells

Iraporda, C., Errea, A. J., Romanin, D., Cayet, D., Pereyra, E. N., Pignataro, O. P., Sirard, J., Garrote, G. L., Abraham, A. G., & Rumbo, M. (2015) · Immunobiology · doi:10.1016/j.imbio.2015.06.004 · Cited by 284 · see citing works

Short-chain fatty acids as feed supplements for sustainable aquaculture: an updated view

Hoseinifar, S. H., Sun, Y., & Caipang, C. M. A. (2016) · Aquaculture Research · doi:10.1111/are.13239 · Cited by 282 · see citing works

Gut microbiota and gastrointestinal health: current concepts and future directions

Aziz, Q., Doré, J., Emmanuel, A., Guarner, F., & Quigley, E. M. M. (2013) · Neurogastroenterology & Motility · doi:10.1111/nmo.12046 · Cited by 280 · see citing works

Ageing and gut microbes: Perspectives for health maintenance and longevity

Biagi, E., Candela, M., Turroni, S., Garagnani, P., Franceschi, C., & Brigidi, P. (2013) · Pharmacological Research · doi:10.1016/j.phrs.2012.10.005 · Cited by 276 · see citing works

The nutrition‐gut microbiome‐physiology axis and allergic diseases

McKenzie, C. I., Tan, J., Macia, L., & Mackay, C. R. (2017) · Immunological Reviews · doi:10.1111/imr.12556 · Cited by 271 · see citing works

TLR4 regulates RORγt+ regulatory T-cell responses and susceptibility to colon inflammation through interaction with Akkermansia muciniphila

Liu, Y., Yang, M., Tang, L., Wang, F., Huang, S., Liu, S., Lei, Y., Wang, S., Xie, Z., Wang, W., et al. (2022) · Microbiome · doi:10.1186/s40168-022-01296-x · Cited by 270 · see citing works

Gut Fermentation of Dietary Fibres: Physico-Chemistry of Plant Cell Walls and Implications for Health

Williams, B. A., Grant, L. J., Gidley, M. J., & Mikkelsen, D. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18102203 · Cited by 255 · see citing works

Microbiome and pathogen interaction with the immune system

Kogut, M. H., Lee, A., & Santín, E. (2020) · Poultry Science · doi:10.1016/j.psj.2019.12.011 · Cited by 254 · see citing works

Gut microbiota, host health, and polysaccharides

Xu, X., Xu, P., Ma, C., Tang, J., & Zhang, X. (2012) · Biotechnology Advances · doi:10.1016/j.biotechadv.2012.12.009 · Cited by 245 · see citing works

Bacteroides and related species: The keystone taxa of the human gut microbiota

Shin, J. H., Tillotson, G., MacKenzie, T. N., Warren, C. A., Wexler, H. M., & Goldstein, E. J. C. (2024) · Anaerobe · doi:10.1016/j.anaerobe.2024.102819 · Cited by 245 · see citing works

Microbial ‘Old Friends’, immunoregulation and stress resilience

Rook, G. A. W., Lowry, C. A., & Raison, C. L. (2013) · Evolution Medicine and Public Health · doi:10.1093/emph/eot004 · Cited by 245 · see citing works

Metabolism meets immunity: The role of free fatty acid receptors in the immune system

Alvarez‐Curto, E., & Milligan, G. (2016) · Biochemical Pharmacology · doi:10.1016/j.bcp.2016.03.017 · Cited by 240 · see citing works

Probiotic, prebiotic and synbiotic supplements in sturgeon aquaculture: a review

Hoseinifar, S. H., Ringø, E., Masouleh, A. S., & Esteban, M. Á. (2014) · Reviews in Aquaculture · doi:10.1111/raq.12082 · Cited by 238 · see citing works

Dietary supplementation of fructooligosaccharide (FOS) improves the innate immune response, stress resistance, digestive enzyme activities and growth performance of Caspian roach (Rutilus rutilus) fry

Soleimani, N., Hoseinifar, S. H., Merrifield, D. L., Barati, M., & Abadi, Z. H. (2011) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2011.11.023 · Cited by 235 · see citing works

Inside the Mucosal Immune System

McGhee, J. R., & Fujihashi, K. (2012) · PLoS Biology · doi:10.1371/journal.pbio.1001397 · Cited by 225 · see citing works

Food for thought: The role of nutrition in the microbiota-gut–brain axis

Oriach, C. S., Robertson, R. C., Stanton, C., Cryan, J. F., & Dinan, T. G. (2016) · Clinical Nutrition Experimental · doi:10.1016/j.yclnex.2016.01.003 · Cited by 227 · see citing works

Rainbow trout (Oncorhynchus mykiss) gut microbiota is modulated by insect meal from Hermetia illucens prepupae in the diet

Terova, G., Rimoldi, S., Ascione, C., Gini, E., Ceccotti, C., & Gasco, L. (2019) · Reviews in Fish Biology and Fisheries · doi:10.1007/s11160-019-09558-y · Cited by 227 · see citing works

The gut microbiota and its role in the development of allergic disease: A wider perspective

West, C. E., Jenmalm, M. C., & Prescott, S. L. (2015) · Clinical & Experimental Allergy · doi:10.1111/cea.12332 · Cited by 223 · see citing works

The impact of microbiota and diet on asthma

Adrover, C. S., & Marull, I. P. (2017) · Dipòsit Digital de Documents de la UAB (Universitat Autònoma de Barcelona)

Microbiota and dietary interactions – an update to the hygiene hypothesis?

Frei, R., Lauener, R. P., Crameri, R., & O’Mahony, L. (2012) · Allergy · doi:10.1111/j.1398-9995.2011.02783.x · Cited by 127 · see citing works

The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces

Statovci, D., Aguilera, M., MacSharry, J. A., & Melgar, S. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00838 · Cited by 490 · see citing works

Editorial: Dietary habits, microbiota and autoimmune diseases

Pucca, M. B., Villena, J., & de Oliveira, G. L. V. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1233863 · Cited by 5 · see citing works

Environmental influences on childhood asthma—The effect of diet and microbiome on asthma

Lunjani, N., Walsh, L., Venter, C., Power, M., MacSharry, J. A., Murphy, D. M., & O’Mahony, L. (2022) · Pediatric Allergy and Immunology · doi:10.1111/pai.13892 · Cited by 28 · see citing works