Cited by 137Aquaculture disease management and microbiotaAquaculture Nutrition and GrowthAnimal Nutrition and Physiology

Enrichment of gilthead seabream (Sparus aurata L.) diet with microalgae: effects on the immune system

Cerezuela, Rebeca, Guardiola, Francisco Antonio, Meseguer, José, Esteban, M. Ángeles·2012·Fish Physiology and Biochemistry

Abstract

The present study assessed the effects of three orally administered microalgae (Nannochloropsis gaditana, Tetraselmis chuii and Phaeodactylum tricornutum) on different immune parameters and immune-related gene expression of gilthead seabream (Sparus aurata L.). Fish were fed a control or one of six experimental diets and sampled at 2 and 4 weeks of treatment. At the end of the trial, growth performance and different systemic and local immune activities were measured (natural haemolytic complement activity, IgM levels, phagocytosis and respiratory burst). The expression levels of different immune-associated genes (EF-1α, IgM(H), TCR-β, MHCIα, MHCIIα, CSF-1R and β-defensin) were analysed in head-kidney and gut. Administration of N. gaditana and T. chuii resulted in a significant increase in haemolytic complement activity, phagocytic capacity, as well expression level of β-defensin, as well as MHCIIα and CSF-1R, respectively. The P. tricornutum-supplemented diet provoked immunostimulation, and very little effect on gene expression was observed. These results suggest that dietary microalgae enhance gilthead seabream defence activity, which could be very important in order to consider such microalgae as a possible additive in fish diets.

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Crossref · 10.1007/s10695-012-9670-9

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  • Administration of Tetraselmis chuii, Nannochloropsis gaditana, and P. tricornutum orally enhanced the defence activity of gilthead seabream.

    “In another study, administration of (Tetraselmis chuii, Nannochloropsis gaditana, and P. tricornutum) orally enhanced the defence activity of gilthead seabream (S. aurata) (Cerezuela et al., 2012).”

    From Potential of microalgae as a sustainable feed ingredient for aquaculture (2021) · cites this paper as Cerezuela et al., 2012

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Authors
Cerezuela, R., Guardiola, F. A., Meseguer, J., & Esteban, M. Á.
Affiliations
Universidad de Murcia (ES)
Corresponding author
Esteban, M. Ángeles
Venue
Fish Physiology and Biochemistry
Published
2012-12
Volume
38
Issue
6
Pages
1729-1739
ISSN
  • 0920-1742 (ISSN-L)
  • 1573-5168
OpenAlex
W2048560883
Cited by
137
References
41
Citations by year
2026: 8 · 2025: 11 · 2024: 11 · 2023: 10 · 2022: 21 · 2021: 22 · 2020: 17 · 2019: 11 · 2018: 4 · 2017: 9 · 2016: 2 · 2015: 4 · 2014: 4 · 2013: 2 · 2012: 1
FWCI
1.53
Type
journal article
Language
en
Open access
closed
Locations
  • Fish Physiology and Biochemistry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Immunology and Microbiology › Immunology › Aquaculture disease management and microbiota
  • Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Aquaculture Nutrition and Growth
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
Keywords
Sparus aurata, Nannochloropsis gaditana, Tetraselmis chuii, Phaeodactylum tricornutum, fish immunity, immunostimulation, IgM, phagocytosis, respiratory burst, immune gene expression, beta-defensins, MHC class II, CSF1R, head kidney, intestine, fish feed additives
MeSH terms
Animals, Animal Feed, Animal Nutritional Physiological Phenomena, Diet, Immunoglobulin M, Leukocytes, Respiratory Burst, Sea Bream, Microalgae, Real-Time Polymerase Chain Reaction

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