Nucleotide excision repair and cancer

Genome maintenance mechanisms for preventing cancer

Hoeijmakers, J. H. J. (2001) · Nature · doi:10.1038/35077232 · Cited by 3,939 · see citing works

Human DNA Repair Genes

Wood, R., Mitchell, M., Sgouros, J., & Lindahl, T. (2001) · Science · doi:10.1126/science.1056154 · Cited by 1,719 · see citing works

Quality Control by DNA Repair

Lindahl, T. L., & Wood, R. D. (1999) · Science · doi:10.1126/science.286.5446.1897 · Cited by 1,489 · see citing works

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η

Masutani, C., Kusumoto, R., Yamada, A., Dohmae, N., Yokoi, M., Yuasa, M., Araki, M., Iwai, S., Takio, K., & Hanaoka, F. (1999) · Nature · doi:10.1038/21447 · Cited by 1,292 · see citing works

Xeroderma Pigmentosum

Kraemer, K. H. (1987) · Archives of Dermatology · doi:10.1001/archderm.123.2.241 · Cited by 1,205 · see citing works

Cockayne syndrome: Review of 140 cases

Nance, M. A., & Berry, S. A. (1992) · American Journal of Medical Genetics · doi:10.1002/ajmg.1320420115 · Cited by 806 · see citing works

Xeroderma Pigmentosum

Robbins, J. H., Kraemer, K. H., Lutzner, M. A., Festoff, B. W., & COON, H. G. (1974) · Annals of Internal Medicine · doi:10.7326/0003-4819-80-2-221 · Cited by 751 · see citing works

The Genetic Basis of Human Cancer

Michels, V. V. (1999) · Mayo Clinic Proceedings · doi:10.4065/74.1.107-a · Cited by 734 · see citing works

<i>hRAD30</i> Mutations in the Variant Form of Xeroderma Pigmentosum

Johnson, R. E., Kondratick, C. M., Prakash, S., & Prakash, L. (1999) · Science · doi:10.1126/science.285.5425.263 · Cited by 732 · see citing works

Nucleotide excision repair and human syndromes

de Boer, J., & Hoeijmakers, J. H. J. (2000) · Carcinogenesis · doi:10.1093/carcin/21.3.453 · Cited by 674 · see citing works

THE BIOLOGY OF THE (6–4) PHOTOPRODUCT

MITCHELL, D. L., & NAIRN, R. S. (1989) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1989.tb05578.x · Cited by 592 · see citing works

Replicative Senescence: Implications for in Vivo Aging and Tumor Suppression

Smith, J. R., & Pereira-Smith, O. M. (1996) · Science · doi:10.1126/science.273.5271.63 · Cited by 547 · see citing works

Xeroderma pigmentosum variant (XP‐V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity

Masutani, C., Araki, M., Yamada, A., Kusumoto, R., Nogimori, T., Maekawa, T., Iwai, S., & Hanaoka, F. (1999) · The EMBO Journal · doi:10.1093/emboj/18.12.3491 · Cited by 434 · see citing works

A Review of Sunscreen Safety and Efficacy

Gasparro, F. P., Mitchnick, M. A., & Nash, J. F. (1998) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1998.tb09677.x · Cited by 423 · see citing works

DNA repair and aging in basal cell carcinoma: a molecular epidemiology study.

Wei, Q., Matanoski, G. M., Farmer, E. R., Hedayati, M. A., & Grossman, L. I. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.4.1614 · Cited by 414 · see citing works

Effect of topically applied T4 endonuclease V in liposomes on skin cancer in xeroderma pigmentosum: a randomised study

Yarosh, D., Klein, J., O'Connor, A., Hawk, J., Rafal, E., & Wolf, P. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04214-8 · Cited by 390 · see citing works

The xeroderma pigmentosum group D (XPD) gene: one gene, two functions, three diseasesPreprint

Lehmann, A. R. (2001) · Genes & Development · doi:10.1101/gad.859501 · Cited by 370 · see citing works

<i>In vitro</i> repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients

Reardon, J. T., Bessho, T., Kung, H. C., Bolton, P. H., & Sancar, A. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.17.9463 · Cited by 366 · see citing works

Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair

Takebayashi, Y., Pourquier, P., Zimonjic, D. B., Nakayama, K., Emmert, S., Ueda, T., Urasaki, Y., Kanzaki, A., Akiyama, S., Popescu, N. C., et al. (2001) · Nature Medicine · doi:10.1038/91008 · Cited by 348 · see citing works

A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A

Giglia‐Mari, G., Coin, F., Ranish, J. A., Hoogstraten, D., Theil, A. F., Wijgers, N., Jaspers, N. G. J., Raams, A., Argentini, M., van der Spek, P. J., et al. (2004) · Nature Genetics · doi:10.1038/ng1387 · Cited by 334 · see citing works

Xeroderma Pigmentosum Complementation Group C Cells Remove Pyrimidine Dimers Selectively from the Transcribed Strand of Active Genes

Venema, J., van Hoffen, A., Karcagi, V., Natarajan, A. T., van Zeeland, A. A., & Mullenders, L. H. F. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.8.4128 · Cited by 317 · see citing works

Reduced DNA repair capacity in lung cancer patients.

Wei, Q., Cheng, L., Hong, W. K., & Spitz, M. R. (1996) · PubMed · Cited by 299 · see citing works

Defective repair of cisplatin-induced DNA damage caused by reduced XPA protein in testicular germ cell tumours

Köberle, B., Masters, J. R., Hartley, J. A., & Wood, R. D. (1999) · Current Biology · doi:10.1016/s0960-9822(99)80118-3 · Cited by 298 · see citing works

Enzyme plus light therapy to repair DNA damage in ultraviolet-B-irradiated human skin

Stege, H., Roza, L., Vink, A. A., Grewe, M., Ruzicka, T., Grether-Beck, S., & Krutmann, J. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.030528897 · Cited by 292 · see citing works

Trichothiodystrophy: Update on the sulfur-deficient brittle hair syndromes

Itin, P. H., Sarasin, A. R., & Pittelkow, M. R. (2001) · Journal of the American Academy of Dermatology · doi:10.1067/mjd.2001.114294 · Cited by 292 · see citing works

Base Excision Repair of Oxidative DNA Damage Activated by XPG Protein

Klungland, A., Höss, M., Gunz, D., Constantinou, A., Clarkson, S. G., Doetsch, P. W., Bolton, P. H., Wood, R. D., & Lindahl, T. L. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80172-0 · Cited by 291 · see citing works

Unified catalytic mechanism for DNA glycosylases

Dodson, M. L., Michaels, M. L., & Lloyd, R. S. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)30047-8 · Cited by 268 · see citing works

DNA damage recognition during nucleotide excision repair in mammalian cells

Wood, R. D. (1999) · Biochimie · doi:10.1016/s0300-9084(99)80036-4 · Cited by 264 · see citing works

Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD/ERCC2 genotypes

Qiao, Y., Spitz, M. R., Shen, H., Guo, Z., Shete, S. S., Hedayati, M. A., Grossman, L. I., Mohrenweiser, H. W., & Wei, Q. (2002) · Carcinogenesis · doi:10.1093/carcin/23.2.295 · Cited by 263 · see citing works

Xeroderma pigmentosum and trichothiodystrophy are associated with different mutations in the XPD ( ERCC 2) repair/transcription gene

Taylor, E. M., Broughton, B. C., Botta, E., Stefanini, M., Sarasin, A. R., Jaspers, N. G. J., Fawcett, H., Harcourt, S. A., Arlett, C. F., & Lehmann, A. R. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.16.8658 · Cited by 262 · see citing works

Opening of an RNA polymerase II promoter occurs in two distinct steps and requires the basal transcription factors IIE and IIH.

Holstege, F. C. P., van der Vliet, P. C., & Timmers, H. T. M. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00512.x · Cited by 257 · see citing works

Cockayne syndrome and xeroderma pigmentosum

Rapin, I., Lindenbaum, Y., Dickson, D. W., Kraemer, K. H., & Robbins, J. H. (2000) · Neurology · doi:10.1212/wnl.55.10.1442 · Cited by 255 · see citing works

DNA mismatch repair and mutation avoidance pathways

Marti, T. M., Kunz, C., & Fleck, O. (2002) · Journal of Cellular Physiology · doi:10.1002/jcp.10077 · Cited by 253 · see citing works

Xeroderma Pigmentosum: Variants with Normal Dna Repair and Normal Sensitivity to Ultraviolet Light

Cleaver, J. E. (1972) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12538913 · Cited by 245 · see citing works

Nucleotide excision repair: From E. coli to man

Petit, C. R., & Sancar, A. (1999) · Biochimie · doi:10.1016/s0300-9084(99)80034-0 · Cited by 230 · see citing works

On diseases of the skin, including the exanthemata

Hebra, F., Kaposi, M., Fagge, C. H., Pye-Smith, P. H., & Tay, W. K. (1866) · Medical Entomology and Zoology · Cited by 228 · see citing works

Engagement with transcription

Bootsma, D., & Hoeijmakers, J. H. J. (1993) · Nature · doi:10.1038/363114a0 · Cited by 228 · see citing works

Photocarcinogenesis: Mechanisms, Models and Human Health Implications: Introduction

Mukhtar, H., & Elmets, C. A. (1996) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1996.tb03040.x · Cited by 219 · see citing works

Characterization of a human DNA damage binding protein implicated in xeroderma pigmentosum E.

Keeney, S., Chang, G. J., & Linn, S. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)36923-6 · Cited by 213 · see citing works

Xeroderma pigmentosum and the role of UV-induced DNA damage in skin cancer

STEEG, H. V., & Kraemer, K. H. (1999) · Molecular Medicine Today · doi:10.1016/s1357-4310(98)01394-x · Cited by 211 · see citing works

Restoration of ultraviolet-induced unscheduled DNA synthesis of xeroderma pigmentosum cells by the concomitant treatment with bacteriophage T4 endonuclease V and HVJ (Sendai virus).

Tanaka, K., Sekiguchi, M., & Okada, Y. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.10.4071 · Cited by 209 · see citing works

Purification and interaction properties of the human RNA polymerase B(II) general transcription factor BTF2.

Gérard, M., Fischer, L., Moncollin, V., Chipoulet, J.-M., Chambon, P., & Egly, J. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54801-8 · Cited by 200 · see citing works

Trichothiodystrophy: sulfur-deficient brittle hair as a marker for a neuroectodermal symptom complex

Price, V. H. (1980) · Archives of Dermatology · doi:10.1001/archderm.116.12.1375 · Cited by 199 · see citing works

Reduced DNA repair capacity in head and neck cancer patients.

Cheng, L., Eicher, S. A., Guo, Z., Hong, W. K., Spitz, M. R., & Wei, Q. (1998) · PubMed · Cited by 192 · see citing works

Polymorphisms in the DNA repair gene XPD: correlations with risk and age at onset of basal cell carcinoma.

Dybdahl, M., Vogel, U. B., FRENTZ, G., Wallin, H., & Nexø, B. A. (1999) · PubMed · Cited by 182 · see citing works

Three complementation groups in Cockayne syndrome

Lehmann, A. R. (1982) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(82)90115-4 · Cited by 176 · see citing works

XPA polymorphism associated with reduced lung cancer risk and a modulating effect on nucleotide excision repair capacity

Wu, X. (2003) · Carcinogenesis · doi:10.1093/carcin/24.3.505 · Cited by 175 · see citing works

Molecular analysis of mutations in DNA polymerase η in xeroderma pigmentosum-variant patients

Broughton, B. C., Cordonnier, A. M., Kleijer, W. J., Jaspers, N. G. J., Fawcett, H., Raams, A., Garritsen, V. H., Stary, A., Avril, M., Boudsocq, F., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.022473899 · Cited by 170 · see citing works

A mutation in the XPB/ERCC3 DNA repair transcription gene, associated with trichothiodystrophy.

Weeda, G., Eveno, E., Donker, I., Vermeulen, W., Chevallier, O., Taı̈eb, A., Stary, A., Hoeijmakers, J. H. J., Mezzina, M., & Sarasin, A. R. (1997) · Europe PMC (PubMed Central) · Cited by 169 · see citing works

The human XPC DNA repair gene: arrangement, splice site information content and influence of a single nucleotide polymorphism in a splice acceptor site on alternative splicing and function

Khan, S. G. (2002) · Nucleic Acids Research · doi:10.1093/nar/gkf469 · Cited by 163 · see citing works

Molecular Analysis of Mutations in the CSB(ERCC6) Gene in Patients with Cockayne Syndrome

Mallery, D. L., Tanganelli, B., Colella, S., Steingrimsdottir, H., van Gool, A. J., Troelstra, C., Stefanini, M., & Lehmann, A. R. (1998) · The American Journal of Human Genetics · doi:10.1086/301686 · Cited by 162 · see citing works

Cockayne Syndrome Group B Cellular and Biochemical Functions

Licht, C. L., Stevnsner, T., & Bohr, V. A. (2003) · The American Journal of Human Genetics · doi:10.1086/380399 · Cited by 158 · see citing works

Pyrimidine dimer removal enhanced by DNA repair liposomes reduces the incidence of UV skin cancer in mice.

Yarosh, D. B., Alas, L., Yee, V., Oberyszyn, T. M., Kibitel, J. T., Mitchell, D. L., Rosenstein, R. B., Spinowitz, A. L., & Citron, M. L. (1992) · PubMed · Cited by 152 · see citing works

Repair of UV Light-Induced DNA Damage and Risk of Cutaneous Malignant Melanoma

Wei, Q., Lee, J. E., Gershenwald, J. E., Ross, M. I., Mansfield, P. F., Strom, S. S., Wang, L., Guo, Z., Qiao, Y., Amos, C. I., et al. (2003) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/95.4.308 · Cited by 148 · see citing works

Nucleotide excision repair gene XPD polymorphisms and genetic predisposition to melanoma

Tomescu, D. (2001) · Carcinogenesis · doi:10.1093/carcin/22.3.403 · Cited by 145 · see citing works

Three Unusual Repair Deficiencies Associated with Transcription Factor BTF2(TFIIH): Evidence for the Existence of a Transcription SyndromePreprint

Vermeulen, W., van Vuuren, A. J., Chipoulet, M., Schaeffer, L., Appeldoorn, E., Weeda, G., Jaspers, N. G. J., Priestley, A., Arlett, C. F., Lehmann, A. R., et al. (1994) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1994.059.01.036 · Cited by 143 · see citing works

Localization of Liposomes Containing a DNA Repair Enzyme in Murine Skin

Yarosh, D., Bucana, C., Cox, P. A. T., Alas, L., Kibitel, J., & Kripke, M. (1994) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12395551 · Cited by 142 · see citing works

X-Ray Structure of T4 Endonuclease V: an Excision Repair Enzyme Specific for a Pyrimidine Dimer

Morikawa, K., Matsumoto, O., Tsujimoto, M., Katayanagi, K., Ariyoshi, M., Doi, T., Ikehara, M., Inaoka, T., & Ohtsuka, E. (1992) · Science · doi:10.1126/science.1575827 · Cited by 140 · see citing works

Xeroderma pigmentosum (complementation group D) mutation is present in patients affected by trichothiodystrophy with photosensitivity

Stefanini, M., Lagomarsini, P., Arlett, C. F., Marinoni, S., Borrone, C., Crovato, F., Trevisan, G., Cordone, G., & Nuzzo, F. (1986) · Human Genetics · doi:10.1007/bf00282072 · Cited by 138 · see citing works

Xeroderma pigmentosum

Kraemer, K. H., & Slor, H. (1985) · Clinics in Dermatology · doi:10.1016/0738-081x(85)90096-3 · Cited by 134 · see citing works

Cerebro-Oculo-Facio-Skeletal Syndrome with a Nucleotide Excision–Repair Defect and a Mutated XPD Gene, with Prenatal Diagnosis in a Triplet Pregnancy

Graham, J. M., Anyane‐Yeboa, K., Raams, A., Appeldoorn, E., Kleijer, W. J., Garritsen, V. H., Busch, D. B., Edersheim, T. G., & Jaspers, N. G. J. (2001) · The American Journal of Human Genetics · doi:10.1086/321295 · Cited by 133 · see citing works

Mutations in the xeroderma pigmentosum group D DNA repair/transcription gene in patients with trichothiodystrophy

Broughton, B. C., Steingrimsdottir, H., Weber, C. A., & Lehmann, A. R. (1994) · Nature Genetics · doi:10.1038/ng0694-189 · Cited by 132 · see citing works

Role of Two Histidines in the (6-4) Photolyase Reaction

Hitomi, K., Nakamura, H., Kim, S., Mizukoshi, T., Ishikawa, T., Iwai, S., & Todo, T. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008828200 · Cited by 126 · see citing works

A new nucleotide-excision-repair gene associated with the disorder trichothiodystrophy.

Stefanini, M., Vermeulen, W., Weeda, G., Giliani, S. C., Nardò, T., Mezzina, M., Sarasin, A. R., Harper, J. I., Arlett, C. F., & Hoeijmakers, J. H. J. (1993) · Europe PMC (PubMed Central) · Cited by 119 · see citing works

Xeroderma Pigmentosum and Related Disorders: Examining the Linkage Between Defective DNA Repair and Cancer

Kraemer, K. H., Levy, D. D., Parris, C. N., Gozukara, E. M., Moriwaki, S., Adelberg, S., & Seidman, M. M. (1994) · Journal of Investigative Dermatology · doi:10.1038/jid.1994.17 · Cited by 118 · see citing works

Relationship of neurologic degeneration to genotype in three xeroderma pigmentosum group G patients

Emmert, S., Slor, H., Busch, D. B., Batko, S., Albert, R. B., Coleman, D., Khan, S. G., Abu-Libdeh, B., DiGiovanna, J. J., Cunningham, B. B., et al. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.01782.x · Cited by 111 · see citing works

Manitoba Aboriginal Kindred with Original Cerebro-Oculo-Facio-Skeletal Syndrome Has a Mutation in the Cockayne Syndrome Group B (CSB) Gene

Meira, L. B., Graham, J. M., Greenberg, C. R., Busch, D. B., Doughty, A. T. B., Ziffer, D. W., Coleman, D. M., Savre‐Train, I., & Friedberg, E. C. (2000) · The American Journal of Human Genetics · doi:10.1086/302867 · Cited by 109 · see citing works

Assessment of 3 xeroderma pigmentosum group C gene polymorphisms and risk of cutaneous melanoma: a case–control study

Blankenburg, S., König, I. R., Mößner, R., Laspe, P., Thoms, K., Krüger, U., Khan, S. G., Westphal, G., Berking, C., Volkenandt, M., et al. (2005) · Carcinogenesis · doi:10.1093/carcin/bgi055 · Cited by 109 · see citing works

Model for XPC-independent Transcription-coupled Repair of Pyrimidine Dimers in Humans

Mu, D., & Sancar, A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.12.7570 · Cited by 106 · see citing works

Two individuals with features of both xeroderma pigmentosum and trichothiodystrophy highlight the complexity of the clinical outcomes of mutations in the XPD gene

Broughton, B. C. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.22.2539 · Cited by 106 · see citing works

Recognition of nonhybridizing base pairs during nucleotide excision repair of DNA

Buschta-Hedayat, N., Buterin, T., Hess, M. T., Missura, M., & Naegeli, H. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.11.6090 · Cited by 103 · see citing works

NEUROLOGICAL DISEASE IN XERODERMA PIGMENTOSUM: DOCUMENTATION OF A LATE ONSET TYPE OF THE JUVENILE ONSET FORM

Robbins, J. H., Brumback, R. A., MENDIONES, M., Barrett, S. F., Carl, J. R., Cho, S., DENCKLA, M. B., Ganges, M. B., Gerber, L. H., Guthrie, R. A., et al. (1991) · Brain · doi:10.1093/brain/114.3.1335 · Cited by 102 · see citing works

Reduced XPC DNA repair gene mRNA levels in clinically normal parents of xeroderma pigmentosum patients

Khan, S. G., Oh, K., Shahlavi, T., Ueda, T., Busch, D. B., Inui, H., Emmert, S., Imoto, K., Muniz-Medina, V. M., Baker, C. C., et al. (2005) · Carcinogenesis · doi:10.1093/carcin/bgi204 · Cited by 99 · see citing works

The human XPG gene: gene architecture, alternative splicing and single nucleotide polymorphisms

Emmert, S. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.7.1443 · Cited by 95 · see citing works

Cancer in Families With Xeroderma Pigmentosum 2

Swift, M., & Chase, C. L. (1979) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/62.6.1415 · Cited by 94 · see citing works

Xeroderma pigmentosum. Defective DNA repair causes skin cancer and neurodegeneration

Robbins, J. H. (1988) · JAMA · doi:10.1001/jama.260.3.384 · Cited by 92 · see citing works

Xeroderma Pigmentosum Complementation Group C Cells Remove Pyrimidine Dimers Selectively from the Transcribed Strand of Active Genes

Venema, J., van Hoffen, A., Karcagi, V., et al. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.8.4128-4134.1991 · Cited by 92 · see citing works

Genetic analysis of twenty-two patients with Cockayne syndrome

Stefanini, M., Fawcett, H., Botta, E., Nardò, T., & Lehmann, A. R. (1996) · Human Genetics · doi:10.1007/bf02267059 · Cited by 89 · see citing works

The xeroderma pigmentosum group C gene leads to selective repair of cyclobutane pyrimidine dimers rather than 6-4 photoproducts

Emmert, S., Kobayashi, N., Khan, S. G., & Kraemer, K. H. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.040559697 · Cited by 87 · see citing works

Molecular genetics of xeroderma pigmentosum variant

Gratchev, A., Strein, P., Utikal, J., & Goerdt, S. (2003) · Experimental Dermatology · doi:10.1034/j.1600-0625.2003.00124.x · Cited by 83 · see citing works

Enzyme therapy of xeroderma pigmentosum: safety and efficacy testing of T4N5 liposome lotion containing a prokaryotic DNA repair enzyme

Yarosh, D., Klein, J., Kibitel, J., Alas, L., O'Connor, A., Cummings, B., Grab, D., Gerstein, D., Gilchrest, B. A., Ichihashi, M., et al. (1996) · Photodermatology, Photoimmunology &amp; Photomedicine · doi:10.1111/j.1600-0781.1996.tb00188.x · Cited by 81 · see citing works

DNA Repair Capacity for Ultraviolet Light-Induced Damage Is Reduced in Peripheral Lymphocytes from Patients with Basal Cell Carcinoma

Wei, Q., Matanoski, G. M., Farmer, E. R., Hedayati, M. A., & Grossrnan, L. (1995) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12606207 · Cited by 80 · see citing works

Neurological manifestations in xeroderma pigmentosum

Mimaki, T., Itoh, N., Abe, J., Tagawa, T., Sato, K., Yabuuchi, H., & Takebe, H. (1986) · Annals of Neurology · doi:10.1002/ana.410200112 · Cited by 73 · see citing works

Genetics and skin cancer of xeroderma pigmentosum in Japan.

Takebe, H., Nishigori, C., & Satoh, Y. (1987) · PubMed · Cited by 71 · see citing works

Xeroderma Pigmentosum Group C Splice Mutation Associated with Autism and Hypoglycinemia11An abstract of this manuscript was presented at the annual meeting of the Society for Investigative Dermatology in Washington, DC

Khan, S. G., Levy, H. L., Legerski, R. J., Quackenbush, E. J., Reardon, J. T., Emmert, S., Sancar, A., Li, L., Schneider, T. D., Cleaver, J. E., et al. (1998) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1998.00391.x · Cited by 71 · see citing works

Xeroderma Pigmentosum Complementation Group E Protein (XPE/DDB2): Purification of Various Complexes of XPE and Analyses of Their Damaged DNA Binding and Putative DNA Repair Properties

Kulaksiz-Erkmen, G., Reardon, J. T., & Sancar, A. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.22.9784-9792.2005 · Cited by 65 · see citing works

DNA repair, immunosuppression, and skin cancer.

Gupta, A. K., & Lynch, L. E. (2004) · PubMed · Cited by 65 · see citing works

Molecular mechanisms of deletion formation in Escherichia coli plasmids

Dianov, G. L., Kuzminov, A. V., Mazin, A. V., & Salganik, R. I. (1991) · Molecular and General Genetics MGG · doi:10.1007/bf00282460 · Cited by 64 · see citing works

Mutations that disable the DNA repair gene XPG in a xeroderma pigmentosum group G patient

Nouspikel, T., & Clarkson, S. G. (1994) · Human Molecular Genetics · doi:10.1093/hmg/3.6.963 · Cited by 62 · see citing works

Five polymorphisms in the coding sequence of the xeroderma pigmentosum group D gene

Broughton, B. C., Steingrimsdottir, H., & Lehmann, A. R. (1996) · Mutation Research/DNA Repair · doi:10.1016/0921-8777(95)00054-2 · Cited by 61 · see citing works

DNA Repair and Ultraviolet Mutagenesis in Cells From a New Patient With Xeroderma Pigmentosum Group G and Cockayne Syndrome Resemble Xeroderma Pigmentosum Cells

Moriwaki, S., Stafanim, M., Lehmann, A. R., Hoeijmakers, J. H. J., Robbins, J. H., Rapin, I., Botta, E., Tanganelli, B., Vermeulen, W., Broughton, B. C., et al. (1996) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12584287 · Cited by 61 · see citing works

Genomic structure, chromosomal localization and identification of mutations in the xeroderma pigmentosum variant (XPV) gene

Yuasa, M., Masutani, C., Eki, T., & Hanaoka, F. (2000) · Oncogene · doi:10.1038/sj.onc.1203842 · Cited by 61 · see citing works

Xeroderma pigmentosum: From Symptoms and Genetics to Gene-Based Skin Therapy

Magnaldo, T., & Sarasin, A. R. (2004) · Cells Tissues Organs · doi:10.1159/000079993 · Cited by 58 · see citing works

Ultraviolet-induced mutations in Cockayne syndrome cells are primarily caused by cyclobutane dimer photoproducts while repair of other photoproducts is normal.

Parris, C. N., & Kraemer, K. H. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.15.7260 · Cited by 58 · see citing works

Alterations of DNA Repair in Melanoma Cell Lines Resistant to Cisplatin, Fotemustine, or Etoposide

Rünger, T. M., Emmert, S., Schadendorf, D., Diem, C., Epe, B., & Hellfritsch, D. (2000) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2000.00844.x · Cited by 58 · see citing works

MICRO syndrome: An entity distinct from COFS syndrome

Graham, J. M., Hennekam, R. C. M., Dobyns, W. B., Roeder, E. R., & Busch, D. B. (2004) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.30060 · Cited by 58 · see citing works

Translesion DNA synthesis in the dihydrofolate reductase domain of UV-irradiated CHO cells

Spivak, G., & Hanawalt, P. C. (1992) · Biochemistry · doi:10.1021/bi00144a021 · Cited by 56 · see citing works

Noncomplementary DNA double-strand-break rejoining in bacterial and human cells

King, J. S., Valcarcel, E. R., Rufer, J. T., Phillips, J. W., & William, F. (1993) · Nucleic Acids Research · doi:10.1093/nar/21.5.1055 · Cited by 56 · see citing works

The Founding Members of Xeroderma Pigmentosum Group G Produce XPG Protein with Severely Impaired Endonuclease Activity

Lalle, P., Nouspikel, T. P., Constantinou, A., Thorel, F., & Clarkson, S. G. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.0022-202x.2001.01673.x · Cited by 55 · see citing works

Xeroderma Pigmentosum and Related Disorders: Examining the Linkage Between Defective DNA Repair and Cancer.

Kraemer, K. H., Levy, D. D., Parris, C. N., Gözükara, E. M., Moriwaki, S., Adelberg, S. A., & Seidman, M. M. (1994) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12399329 · Cited by 55 · see citing works

Liposomes in investigative dermatology

Yarosh, D. B. (2001) · Photodermatology Photoimmunology & Photomedicine · doi:10.1034/j.1600-0781.2001.170501.x · Cited by 47 · see citing works

Physical mapping and complete nucleotide sequence of the denV gene of bacteriophage T4

Radany, E. H., Naumovski, L., Love, J. D., Gutekunst, K. A., Hall, D. H., & Friedberg, E. C. (1984) · Journal of Virology · doi:10.1128/jvi.52.3.846-856.1984 · Cited by 45 · see citing works

Mapping the multiple self-healing squamous epithelioma (MSSE) gene and investigation of xeroderma pigmentosum group A (XPA) and PATCHED (PTCH) as candidate genes

Richards, F. M., Goudie, D. R., Cooper, W. N., Jene, Q., Barroso, I., Wicking, C., Wainwright, B. J., & Ferguson-Smith, M. A. (1997) · Human Genetics · doi:10.1007/s004390050635 · Cited by 44 · see citing works

Participation of glutamic acid 23 of T4 endonuclease V in theβ-elimination reaction of an abasic site in a synthetic duplex DNA

Hori, N., Doi, T., Karaki, Y., Kituchi, M., Ikehara, M., & Ohtsuka, E. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.18.4761 · Cited by 44 · see citing works

No association between three xeroderma pigmentosum group C and one group G gene polymorphisms and risk of cutaneous melanoma

Blankenburg, S., König, I. R., Mößner, R., Laspe, P., Thoms, K., Krüger, U., Khan, S. G., Westphal, G., Volkenandt, M., Neumann, C. R., et al. (2004) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5201296 · Cited by 40 · see citing works

Role of DNA damage in local suppression of contact hypersensitivity in mice by UV radiation

Kripke, M. L., Cox, P. A., Bucana, C., Vink, A. A., Alas, L., & Yarosh, D. B. (1996) · Experimental Dermatology · doi:10.1111/j.1600-0625.1996.tb00113.x · Cited by 36 · see citing works

Cockayne syndrome in two adult siblings

Miyauchi, H., Horio, T., Akaeda, T., Asada, Y., Chang, H. R., Ishizaki, K., & Ikenaga, M. (1994) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(94)70034-6 · Cited by 36 · see citing works

DNA repair and resistance to chemotherapy.

Harris, A. L. (1985) · PubMed · Cited by 33 · see citing works

An XPG DNA Repair Defect Causing Mutagen Hypersensitivity in Mouse Leukemia L1210 Cells

Vilpo, J., Vilpo, L. M., Szymkowski, D. E., O’Donovan, A., & Wood, R. D. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.1.290 · Cited by 30 · see citing works

ENHANCEMENT OF ULTRAVIOLET‐DNA REPAIR IN den V GENE TRANSFECTANTS and T4 ENDONUCLEASE V‐LIPOSOME RECIPIENTS

Kibitel, J. T., Yee, V., & Yarosh, D. B. (1991) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1991.tb02086.x · Cited by 29 · see citing works

Syndromes with genetic instability: Model diseases for (skin) cancerogenesis

Emmert, S., Leibeling, D., & Rünger, T. M. (2006) · JDDG Journal der Deutschen Dermatologischen Gesellschaft · doi:10.1111/j.1610-0387.2006.06047.x · Cited by 20 · see citing works

Enhanced pyrimidine dimer removal in repair-proficient murine fibroblasts transforme with the denV gene of bacteriophage T4

Kusewitt, D. F., Ley, R. D., & Henderson, E. E. (1991) · Mutation Research/DNA Repair · doi:10.1016/0921-8777(91)90012-e · Cited by 18 · see citing works

FREQUENCY OF ULTRAVIOLET RADIATION‐INDUCED MUTATION AT THE hprt LOCUS IN REPAIR‐PROFICIENT MURINE FIBROBLASTS TRANSFECTED WITH THE denV GENE OF BACTERIOPHAGE T4

Kusewitt, D. F., Budge, C. L., Anderson, M. M., Ryan, S. L., & Ley, R. D. (1993) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1993.tb09589.x · Cited by 16 · see citing works

Morphological and biochemical characteristics of trichothiodystrophy-variant hair are maintained after grafting of scalp specimens on to nude mice

Neste, D. J. J. V., Gillespie, J. M., MARSHALL, R. C., Taı̈eb, A., & Brouwer, B. D. (1993) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1993.tb00195.x · Cited by 14 · see citing works

DNA Damage and Repair in Human Skin: Pathways and Questions

Sutherland, B. M., Hacham, H., Gange, R. W., Maytum, D. J., & Sutherland, J. C. (1990) · Springer eBooks · doi:10.1007/978-1-4613-0637-5_12 · Cited by 11 · see citing works

Enhanced Pyrimidine Dimer Repair in Cultured Murine Epithelial Cells Transfected with the denV Gene of Bacteriophage T4

Kusewitt, D. F., Budge, C. L., & Ley, R. D. (1994) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12373084 · Cited by 10 · see citing works

The Association of Xeroderma Pigmentosum with Trichothiodystrophy: A Clue to a Better Understanding of XP-D?

Nuzzo, F., & Stefanini, M. (1989) · doi:10.1007/978-1-4757-5016-4_8 · Cited by 9 · see citing works

Repair of cyclobutyl pyrimidine dimers in human skin: variability among normal humans in nucleotide excision and in photorepair

Sutherland, B. M., Hacham, H., Bennett, P. V., Sutherland, J. C., Moran, M. N., & Gange, R. W. (2002) · Photodermatology Photoimmunology & Photomedicine · doi:10.1034/j.1600-0781.2002.00748.x · Cited by 8 · see citing works

Measurement of Activities of Cyclobutane-Pyrimidine-Dimer and (6-4)-Photoproduct Photolyases

Hays, J. B., & Hoffman, P. D. (2003) · Humana Press eBooks · doi:10.1385/1-59259-675-4:133 · Cited by 7 · see citing works

Photoprotektive Mechanismen in menschlicher Haut Modulation durch Oligonukleotide

Hadshiew, I., Eller, M. S., Moll, I., & Gilchrest, B. A. (2002) · Der Hautarzt · doi:10.1007/s001050100286 · Cited by 5 · see citing works

Trichothiodystrophic Hair Reveals an Abnormal Pattern of Viscoelastic Parameters

Tsambaos, D., Nikiforidis, G., Balas, C., & Marinoni, S. (2009) · Skin Pharmacology · doi:10.1159/000211302 · Cited by 3 · see citing works

UV radiation and the skin

D'Orazio, J., Jarrett, S., Amaro-Ortiz, A., & Scott, T. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140612222 · Cited by 1,984 · see citing works

Base excision repair of oxidative DNA damage and association with cancer and aging

Maynard, S., Schurman, S. H., Harboe, C., de Souza-Pinto, N. C., & Bohr, V. A. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn250 · Cited by 685 · see citing works

Eukaryotic Translesion Polymerases and Their Roles and Regulation in DNA Damage Tolerance

Waters, L. S., Minesinger, B. K., Wiltrout, M. E., D'Souza, S., Woodruff, R. V., & Walker, G. C. (2009) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00034-08 · Cited by 591 · see citing works

DNA‐damage repair; the good, the bad, and the ugly

Hakem, R. (2008) · The EMBO Journal · doi:10.1038/emboj.2008.15 · Cited by 547 · see citing works

DNA repair mechanisms in cancer development and therapy

Torgovnick, A., & Schumacher, B. (2015) · Frontiers in Genetics · doi:10.3389/fgene.2015.00157 · Cited by 403 · see citing works

Ultraviolet Radiations: Skin Defense-Damage Mechanism

Mohania, D., Chandel, S. R., Kumar, P., Verma, V., Digvijay, K., Tripathi, D., Choudhury, K., Mitten, S. K., & Shah, D. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-56017-5_7 · Cited by 267 · see citing works

Mechanisms of cadmium induced genomic instability

Filipič, M. (2011) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2011.09.002 · Cited by 236 · see citing works

UV Damage and DNA Repair in Malignant Melanoma and Nonmelanoma Skin Cancer

Rass, K., & Reichrath, J. (2009) · Advances in experimental medicine and biology · doi:10.1007/978-0-387-77574-6_13 · Cited by 220 · see citing works

The Genomes of Three Uneven Siblings: Footprints of the Lifestyles of Three Trichoderma Species

Schmoll, M., Dattenböck, C., Carreras-Villaseñor, N., Mendoza‐Mendoza, A., Tisch, D., Alemán-Duarte, M. I., Baker, S., Brown, C. M., Cervantes-Badillo, M. G., Cetz-Chel, J. E., et al. (2016) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00040-15 · Cited by 190 · see citing works

DNA repair deficiency as a therapeutic target in cancer

Martin, S. A., Lord, C. J., & Ashworth, A. (2008) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2008.01.016 · Cited by 174 · see citing works

Focus on UV-Induced DNA Damage and Repair—Disease Relevance and Protective Strategies

Kciuk, M., Marciniak, B., Mojzych, M., & Kontek, R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21197264 · Cited by 168 · see citing works

Solar radiation and human health

Juzeniene, A., Brekke, P., Dahlback, A., Andersson‐Engels, S., Reichrath, J., Moan, K., Holick, M. F., Grant, W. B., & Moan, J. E. (2011) · Reports on Progress in Physics · doi:10.1088/0034-4885/74/6/066701 · Cited by 162 · see citing works

DNA Repair Proteins as Molecular Targets for Cancer Therapeutics

Kelley, M. R., & Fishel, M. L. (2008) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/187152008784220294 · Cited by 113 · see citing works

Targeting homologous recombination repair defects in cancer

Evers, B., Helleday, T., & Jonkers, J. (2010) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2010.06.001 · Cited by 113 · see citing works

Placental promoter methylation of DNA repair genes and prenatal exposure to particulate air pollution: an ENVIR ON AGE cohort study

Neven, K. Y., Saenen, N. D., Tarantini, L., Janssen, B. G., Lefebvre, W., Vanpoucke, C., Bollati, V., & Nawrot, T. S. (2018) · The Lancet Planetary Health · doi:10.1016/s2542-5196(18)30049-4 · Cited by 103 · see citing works

A Cancer Theory Kerfuffle Can Lead to New Lines of Research

Baker, S. G. (2014) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/dju405 · Cited by 100 · see citing works

DNA Damage Response Pathways in Tumor Suppression and Cancer Treatment

Liang, Y., Lin, S., Brunicardi, F. C., Goss, J. A., & Li, K. (2008) · World Journal of Surgery · doi:10.1007/s00268-008-9840-1 · Cited by 100 · see citing works

Skin cancer in organ transplant recipients: effects of immunosuppressive medications on DNA repair

Kuschal, C., Thoms, K., Schubert, S., Schäfer, A., Boeckmann, L., Schön, M. P., & Emmert, S. (2011) · Experimental Dermatology · doi:10.1111/j.1600-0625.2011.01413.x · Cited by 96 · see citing works

Molecular Mechanisms of Cutaneous Squamous Cell Carcinoma

Hedberg, M. L., Berry, C. T., Moshiri, A. S., Xiang, Y., Yeh, C. J., Atillasoy, C., Capell, B. C., & Seykora, J. T. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073478 · Cited by 89 · see citing works

Paradoxes in carcinogenesis: New opportunities for research directions

Baker, S. G., & Kramer, B. S. (2007) · BMC Cancer · doi:10.1186/1471-2407-7-151 · Cited by 84 · see citing works

Caffeic acid prevents UVB radiation induced photocarcinogenesis through regulation of PTEN signaling in human dermal fibroblasts and mouse skin

Balupillai, A., Prasad, N. R., Ramasamy, K., Govindasamy, K., & Muthusamy, G. (2018) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2018.05.030 · Cited by 81 · see citing works

DNA damage response and repair in colorectal cancer: Defects, regulation and therapeutic implications

Mirza‐Aghazadeh‐Attari, M., Darband, S. G., Kaviani, M., Mihanfar, A., Aghazadeh-Attari, J., Yousefi, B., & Majidinia, M. (2018) · DNA repair · doi:10.1016/j.dnarep.2018.07.005 · Cited by 77 · see citing works

Nucleotide excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African Americans

Chang, J. S.-M., Wrensch, M., Hansen, H. M., Sison, J. D., Aldrich, M. C., Quesenberry, C. P., Seldin, M. F., Kelsey, K. T., Kittles, R. A., SILVA, G. H. D. O., et al. (2008) · International Journal of Cancer · doi:10.1002/ijc.23801 · Cited by 75 · see citing works

Identification of adverse outcome pathway related to high-density polyethylene microplastics exposure: Caenorhabditis elegans transcription factor RNAi screening and zebrafish study

Kim, Y., Jeong, J., Lee, S., Choi, I., & Choi, J. (2019) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2019.121725 · Cited by 72 · see citing works

Trichothiodystrophy view from the molecular basis of DNA repair/transcription factor TFIIH

Hashimoto, S., & Egly, J. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp390 · Cited by 72 · see citing works

Ultraviolet radiation and immunosuppression

MURPHY, G. M. (2009) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2009.09455.x · Cited by 71 · see citing works

Molecular and cellular pathogenesis of melanoma initiation and progression

Regad, T. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1324-2 · Cited by 62 · see citing works

Association between ERCC1 and XPA expression and polymorphisms and the response to cisplatin in testicular germ cell tumours

Mendoza‐Pérez, J., Martínez, J. G., Hernández, C. H., Pérez‐Montiel, D., Castro, C., Fabián-Morales, E., Santibáñez-Andrade, M., González‐Barrios, R., Díaz‐Chávez, J., Andonegui, M. A., et al. (2013) · British Journal of Cancer · doi:10.1038/bjc.2013.303 · Cited by 57 · see citing works

Both genetic and dietary factors underlie individual differences in DNA damage levels and DNA repair capacity

Slyšková, J., Lorenzo, Y., Karlsen, A. S., Carlsen, M. H., Novosadová, V., Blomhoff, R., Vodička, P., & Collins, A. R. (2014) · DNA repair · doi:10.1016/j.dnarep.2014.01.016 · Cited by 56 · see citing works

Cell Reversal From a Differentiated to a Stem-Like State at Cancer Initiation

Carvalho, J. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00541 · Cited by 56 · see citing works

Role of Endonucleases XPF and XPG in Nucleotide Excision Repair of Platinated DNA and Cisplatin/Oxaliplatin Cytotoxicity

Graf, N., Ang, W. H., Zhu, G., Myint, M., & Lippard, S. J. (2011) · ChemBioChem · doi:10.1002/cbic.201000724 · Cited by 55 · see citing works

Targeting and processing of site‐specific DNA interstrand crosslinks

Vásquez, K. M. (2010) · Environmental and Molecular Mutagenesis · doi:10.1002/em.20557 · Cited by 53 · see citing works

Synthesis and bio-evaluation of indole-chalcone based benzopyrans as promising antiligase and antiproliferative agents

Gupta, S., Maurya, P., Upadhyay, A., Kushwaha, P., Krishna, S., Siddiqi, M. I., Sashidhara, K. V., & Banerjee, D. (2017) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2017.11.015 · Cited by 51 · see citing works

Exploring DNA Damage and Repair Mechanisms: A Review with Computational Insights

Chen, J., Potlapalli, R., Quan, H., Chen, L., Xie, Y., Pouriyeh, S., Sakib, N., Liu, L., & Xie, Y. (2024) · BioTech · doi:10.3390/biotech13010003 · Cited by 48 · see citing works

Inherited Cancer Syndromes in Children and Young Adults

D'Orazio, J. A. (2010) · Journal of Pediatric Hematology/Oncology · doi:10.1097/mph.0b013e3181ced34c · Cited by 45 · see citing works

Molecular Mechanisms of H. pylori-Induced DNA Double-Strand Breaks

Kidane, D. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19102891 · Cited by 41 · see citing works

The Emerging Roles of ATP-Dependent Chromatin Remodeling Enzymes in Nucleotide Excision Repair

Czaja, W., Mao, P., & Smerdon, M. J. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms130911954 · Cited by 40 · see citing works

Whole-Exome Sequencing Enables Rapid Determination of Xeroderma Pigmentosum Molecular Etiology

Ortega‐Recalde, O., Vergara, J. I., Fonseca, D. J., Ríos, X. P., Mosquera, H., Bermúdez, O. M., Medina, C. L., Vargas, C. I., Pallares, A. E., Restrepo, C. M., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064692 · Cited by 39 · see citing works

Molecular epidemiology of DNA repair gene polymorphisms and head and neck cancer

Meilin, W., Haiyan, C., Zhang, Z., & Qingyi, W. (2013) · Journal of Biomedical Research · doi:10.7555/jbr.27.20130034 · Cited by 39 · see citing works

DNA Damage and Deficiencies in the Mechanisms of Its Repair: Implications in the Pathogenesis of Systemic Lupus Erythematosus

Mireles-Canales, M. P., González‐Chávez, S. A., Quiñonez-Flores, C. M., León-López, E. A., & Pacheco‐Tena, C. (2018) · Journal of Immunology Research · doi:10.1155/2018/8214379 · Cited by 39 · see citing works

DNA polymerase eta: A potential pharmacological target for cancer therapy

Saha, P., Mandal, T., Talukdar, A. D., Kumar, D., Kumar, S., Tripathi, P. P., Wang, Q., & Srivastava, A. K. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.30155 · Cited by 39 · see citing works

Molecular Biology of Basal and Squamous Cell Carcinomas

Emmert, S., Schön, M. P., & Haenssle, H. A. (2014) · Springer eBooks · doi:10.1007/978-1-4939-0437-2_13 · Cited by 38 · see citing works

Promoter polymorphisms in DNA repair gene ERCC5 and susceptibility to gastric cancer in Chinese

Duan, Z., He, C., Gong, Y., Li, P., Xu, Q., Sun, L. L., Wang, Z., Xing, C., & Yuan, Y. (2012) · Gene · doi:10.1016/j.gene.2012.09.025 · Cited by 37 · see citing works

Association between XPF Polymorphisms and Cancer Risk: A Meta-Analysis

Shi, T., He, J., Qiu, L., Zhu, M., Wang, M., Zhou, X.-Y., Han, J., Yu, H., Zang, R., & Wei, Q. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038606 · Cited by 37 · see citing works

Finding minimum gene subsets with heuristic breadth-first search algorithm for robust tumor classification

Wang, S.-L., Li, X., & Fang, J. (2012) · BMC Bioinformatics · doi:10.1186/1471-2105-13-178 · Cited by 37 · see citing works

Recent Advances in the Biology, Therapy and Management of Melanoma

Davids, L. M. (2013) · InTech eBooks · doi:10.5772/46052 · Cited by 36 · see citing works

An aphidicolin-block nucleotide excision repair assay measuring DNA incision and repair capacity

Loock, K. V., Decordier, I., Ciardelli, R., Haumont, D., & Kirsch‐Volders, M. (2009) · Mutagenesis · doi:10.1093/mutage/gep039 · Cited by 36 · see citing works

The association of polymorphisms in nucleotide excision repair genes with ovarian cancer susceptibility

Zhao, Z., Zhang, A., Zhao, Y., Xiang, J., Yu, D., Liang, Z., Xu, C., Zhang, Q., Li, J., & Duan, P. (2018) · Bioscience Reports · doi:10.1042/bsr20180114 · Cited by 32 · see citing works

Solar radiation and human health

Moan, J. E., & Juzeniene, A. (2010) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2010.08.004 · Cited by 31 · see citing works

Activated or Impaired: An Overview of DNA Repair in Neurodegenerative Diseases

Qin, N., Geng, A., & Xue, R. (2022) · Aging and Disease · doi:10.14336/ad.2021.1212 · Cited by 30 · see citing works

DNA repair pathways and their implication in cancer treatment

Pallis, A. G., & Karamouzis, M. V. (2010) · Cancer and Metastasis Reviews · doi:10.1007/s10555-010-9258-8 · Cited by 30 · see citing works

The NER protein Rad33 shows functional homology to human Centrin2 and is involved in modification of Rad4

den Dulk, B., van Eijk, P., de Ruijter, M., Brandsma, J. A., & Brouwer, J. (2008) · DNA repair · doi:10.1016/j.dnarep.2008.02.004 · Cited by 30 · see citing works

XPG Gene Polymorphisms Contribute to Colorectal Cancer Susceptibility: A Two-Stage Case-Control Study

Hua, R., Zhuo, Z., Zhu, J., Zhang, S.-D., Xue, W., Zhang, J., Xu, H.-M., Li, X., Zhang, P., He, J., et al. (2016) · Journal of Cancer · doi:10.7150/jca.15602 · Cited by 28 · see citing works

Novel Biomarker Candidates for Colorectal Cancer Metastasis: A Meta-analysis of In Vitro Studies

Long, N. P., Lee, W. J., Nguyen, H. T., Lee, S. J., Park, J. H., & Kwon, S. W. (2016) · Cancer Informatics · doi:10.4137/cin.s40301 · Cited by 28 · see citing works

Strict sun protection results in minimal skin changes in a patient with xeroderma pigmentosum and a novel c.2009delG mutation in XPD (ERCC2)

Emmert, S., Ueda, T., Zumsteg, U., Weber, P., Khan, S. G., Oh, K., Boyle, J., Laspe, P., Zachmann, K., Boeckmann, L., et al. (2008) · Experimental Dermatology · doi:10.1111/j.1600-0625.2008.00763.x · Cited by 28 · see citing works

C8-Linked Bulky Guanosine DNA Adducts: Experimental And Computational Insights Into Adduct Conformational Preferences And Resulting Mutagenicity

Millen, A. L., Sharma, P., & Wetmore, S. D. (2012) · Future Medicinal Chemistry · doi:10.4155/fmc.12.138 · Cited by 28 · see citing works

Functional DNA repair system analysis in haematopoietic progenitor cells using host cell reactivation

Thoms, K.-M., Bäsecke, J., Emmert, B., Hermann, J., Roedling, T., Laspe, P., Leibeling, D., Trümper, L. H. P., & Emmert, S. (2007) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365510701230481 · Cited by 27 · see citing works

Challenge and perspective: the relevance of ultraviolet (UV) radiation and the vitamin D endocrine system (VDES) for psoriasis and other inflammatory skin diseases

Reichrath, J., Saternus, R., & VOGT, T. M. (2017) · Photochemical & Photobiological Sciences · doi:10.1039/c6pp00280c · Cited by 27 · see citing works

Association study between XPG Asp1104His polymorphism and colorectal cancer risk in a Chinese population

Du, H., Zhang, X., Du, M., Guo, N., Chen, Z., Shu, Y., Zhang, Z., Wang, M., & Zhu, L. (2014) · Scientific Reports · doi:10.1038/srep06700 · Cited by 26 · see citing works

Reduction of IKKα Expression Promotes Chronic Ultraviolet B Exposure-Induced Skin Inflammation and Carcinogenesis

Xia, X., Park, E., Liu, B., Willette‐Brown, J., Gong, W., Wang, J., Mitchell, D. L., Fischer, S. M., & Hu, Y. (2010) · American Journal Of Pathology · doi:10.2353/ajpath.2010.091041 · Cited by 25 · see citing works

Polymorphisms in nucleotide excision repair genes and risk of primary prostate cancer in Chinese Han populations

Wang, M., Li, Q., Gu, C., Zhu, Y., Yang, Y., Wang, J., Li, J., He, J., Ye, D., & Wei, Q. (2016) · Oncotarget · doi:10.18632/oncotarget.13848 · Cited by 24 · see citing works

Bacterial DNA repair genes and their eukaryotic homologues: 4. The role of nucleotide excision DNA repair (NER) system in mammalian cells.

Maddukuri, L., Dudzińska, D., & Tudek, B. (2007) · Acta Biochimica Polonica · doi:10.18388/abp.2007_3222 · Cited by 24 · see citing works

Nucleotide excision repair pathway gene polymorphisms are associated with risk and prognosis of colorectal cancer

Li, Y., Xu, Q., Sun, L. L., Gong, Y., Jing, J., Xing, C., & Yuan, Y. (2020) · World Journal of Gastroenterology · doi:10.3748/wjg.v26.i3.307 · Cited by 23 · see citing works

Exploring Damage Recognition Models in Prokaryotic Nucleotide Excision Repair with a Benzo[a]pyrene-Derived Lesion in UvrB

Jia, L., Kropachev, K. Y., Ding, S., Houten, B. V., Geacintov, N. E., & Broyde, S. B. (2009) · Biochemistry · doi:10.1021/bi9010072 · Cited by 23 · see citing works

MicroRNA binding mediated Functional sequence variant in 3′-UTR of DNA repair Gene XPC in Age-related Cataract

Zou, X., Kang, L., Yang, M., Wu, J., & Guan, H. (2018) · Scientific Reports · doi:10.1038/s41598-018-33071-0 · Cited by 22 · see citing works

Fluorescent probes for the analysis of DNA strand scission in base excision repair

Matsumoto, N., Toga, T., Hayashi, R., Sugasawa, K., Katayanagi, K., Ide, H., Kuraoka, I., & Iwai, S. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq022 · Cited by 22 · see citing works

Cloning and characterization of DNA polymerase η from Trypanosoma cruzi: Roles for translesion bypass of oxidative damage

de Moura, M. B., Schamber‐Reis, B. L. F., Silva, D. G. P., Rajão, M. A., Macedo, A. M., Franco, G. R., Pena, S. D. J., Teixeira, S. M. R., & Machado, C. R. (2009) · Environmental and Molecular Mutagenesis · doi:10.1002/em.20450 · Cited by 22 · see citing works

The current evidence for defective repair of oxidatively damaged DNA in Cockayne syndrome

Fròsina, G. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.04.001 · Cited by 22 · see citing works

Interplay between the DNA Damage Response and Immunotherapy Response in Cancer

Lee, E. C. Y., Kok, J. S.-T., Teh, B. T., & Lim, K. S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113356 · Cited by 21 · see citing works

Molecular genetic analysis of 16 XP ‐ C patients from G ermany: environmental factors predominately contribute to phenotype variations

Schäfer, A., Hofmann, L., Gratchev, A. N., Laspe, P., Schubert, S., Schürer, K. A., Ohlenbusch, A., Tzvetkov, M. V., Hallermann, C., Reichrath, J., et al. (2012) · Experimental Dermatology · doi:10.1111/exd.12052 · Cited by 21 · see citing works

Measuring urinary 8-hydroxy-2′-deoxyguanosine and malondialdehyde levels in women with overactive bladder

Dokumacıoğlu, E., Demiray, Ö., Dokumacıoğlu, A., Şahin, A., Şen, T. M., & Çankaya, S. (2018) · Korean journal of urology · doi:10.4111/icu.2018.59.4.252 · Cited by 21 · see citing works

Smad4 Loss in Mouse Keratinocytes Leads to Increased Susceptibility to UV Carcinogenesis with Reduced Ercc1-Mediated DNA Repair

Mitra, D., Fernandez, P., Bian, L., Song, N., Li, F., Han, G., & Wang, X. (2013) · Journal of Investigative Dermatology · doi:10.1038/jid.2013.213 · Cited by 19 · see citing works

YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors

Stachelek, G. C., Peterson-Roth, E., Liu, Y., Fernandez, R. J., Pike, L., Qian, J. M., Abriola, L., Hoyer, D., Hungerford, W. M., Merkel, J., et al. (2015) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-15-0036 · Cited by 19 · see citing works

Molecular Biology of Basal and Squamous Cell Carcinomas

Boeckmann, L., Martens, M. C., & Emmert, S. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-46227-7_9 · Cited by 19 · see citing works

Nucleotide excision repair impairment by nodularin in CHO cell lines due to ERCC1/XPF inactivation

Lankoff, A., Sochacki, J., Spoof, L. E. M., Meriluoto, J. A. O., Wójcik, A., Węgierek-Ciuk, A., & Verschaeve, L. (2008) · Toxicology Letters · doi:10.1016/j.toxlet.2008.04.008 · Cited by 19 · see citing works

Efficiency of Base Excision Repair of Oxidative DNA Damage and Its Impact on the Risk of Colorectal Cancer in the Polish Population

Kabziński, J., Mucha, B., Cuchra, M., Markiewicz, Ł., Przybyłowska, K., Dziki, A. J., Dziki, Ł. A., & Majsterek, I. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/3125989 · Cited by 18 · see citing works

Genetic variant in DNA repair geneGTF2H4is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium

Wang, M., Liu, H., Liu, Z., Yi, X., Bickeböller, H., Hung, R. J., Brennan, P., Landi, M. T., Caporaso, N. E., Christiani, D. C., et al. (2016) · Carcinogenesis · doi:10.1093/carcin/bgw070 · Cited by 18 · see citing works

XPC Lys939Gln polymorphism contributes to colorectal cancer susceptibility: evidence from a meta-analysis

Peng, Q., Lao, X., Tang, W., Chen, Z., Li, R., Qin, X. Y., & Li, S. (2014) · Diagnostic Pathology · doi:10.1186/1746-1596-9-120 · Cited by 18 · see citing works

Inhibition of nucleotide excision repair and damage response signaling by dibromoacetonitrile: A novel genotoxicity mechanism of a water disinfection byproduct

Komaki, Y., & Ibuki, Y. (2021) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.127194 · Cited by 17 · see citing works

A Comprehensive Analysis of Influence ERCC Polymorphisms Confer on the Development of Brain Tumors

Geng, P., Ou, J., Li, J., Liao, Y., Wang, N., Xie, G., Sa, R., Liu, C., Xiang, L., & Liang, H. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9371-3 · Cited by 16 · see citing works

The Differential Expression of Core Genes in Nucleotide Excision Repair Pathway Indicates Colorectal Carcinogenesis and Prognosis

Liu, J., Li, H., Sun, L. L., Xue, F., Wang, Z., Yuan, Y., & Xing, C. (2018) · BioMed Research International · doi:10.1155/2018/9651320 · Cited by 16 · see citing works

Genome Damage Sensing Leads to Tissue Homeostasis in Drosophila

Khan, C., Muliyil, S., & Rao, B. J. (2019) · International review of cytology · doi:10.1016/bs.ircmb.2018.12.001 · Cited by 15 · see citing works

Paradox-Driven Cancer Research

Baker, S. G. (2013) · Disruptive Science and Technology · doi:10.1089/dst.2012.0029 · Cited by 15 · see citing works

Melanoma — Epidemiology, Genetics and Risk Factors

John, A., Jarrett, S. G., Marsch, A. F., Lagrew, J. P., & Cleary, L. C. (2013) · InTech eBooks · doi:10.5772/55172 · Cited by 13 · see citing works

Benzo[a]pyrene (BP) DNA adduct formation in DNA repair-deficient p53 haploinsufficient [Xpa(-/-)p53(+/-)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days

John, K., Pratt, M. M., Beland, F. A., Churchwell, M. I., McMullen, G., Olivero, O. A., Pogribny, I. P., & Poirier, M. C. (2012) · Carcinogenesis · doi:10.1093/carcin/bgs247 · Cited by 13 · see citing works

Xeroderma Pigmentosum, Cockayne Syndrome and Trichothiodystrophy

Emmert, S. (2011) · Wiley eBooks · doi:10.1002/9781444345384.ch135 · Cited by 13 · see citing works

Busca de variantes em sequência de DNA proveniente de pacientes com deficiência em processos de reparo do genoma

Moura, L. M. S. (2015) · doi:10.11606/d.95.2015.tde-10112015-173956 · Cited by 13 · see citing works

The Enigmatic Role of TP53 in Germ Cell Tumours: Are We Missing Something?

Ottaviano, M., Giunta, E. F., Rescigno, P., Mestre, R. P., Marandino, L., Tortora, M., Riccio, V., Parola, S., Casula, M., Paliogiannis, P., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22137160 · Cited by 12 · see citing works

The Curcumin Analog PAC Is a Potential Solution for the Treatment of Triple-Negative Breast Cancer by Modulating the Gene Expression of DNA Repair Pathways

Almalki, E., Al-Amri, A., Alrashed, R., Al-Zharani, M. M., & Semlali, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24119649 · Cited by 12 · see citing works

The Role of Surgery in Cancer Prevention

Jatoi, I., Benson, J. R., Liau, S., Chen, Y., Cisco, R. M., Norton, J. A., Moley, J. F., Khalifeh, K. W., & Choti, M. A. (2010) · Current Problems in Surgery · doi:10.1067/j.cpsurg.2010.06.002 · Cited by 12 · see citing works

DNA damage and repair in leukocytes of melanoma patients exposed in vitro to cisplatin

Shimabukuro, F., Neto, C. F., Sanches, J. A., & Gattás, G. J. F. (2011) · Melanoma Research · doi:10.1097/cmr.0b013e3283426839 · Cited by 11 · see citing works

A meta-analysis of evidences on XPC polymorphisms and lung cancer susceptibility

Liu, C., Yin, Q., Hu, J., Li, L., Zhang, Y., & Wang, Y. (2013) · Tumor Biology · doi:10.1007/s13277-013-0663-9 · Cited by 10 · see citing works

Xeroderma pigmentosum

Emmert, B., Hallier, E., Schön, M. P., & Emmert, S. (2011) · Der Hautarzt · doi:10.1007/s00105-010-2050-4 · Cited by 10 · see citing works

Xeroderma Pigmentosum

Stefanini, M., & Kraemer, K. H. (2008) · Springer eBooks · doi:10.1007/978-3-211-69500-5_51 · Cited by 10 · see citing works

Identification of Intermediate-Size Non-Coding RNAs Involved in the UV-Induced DNA Damage Response in C. elegans

Li, A., Wei, G., Wang, Y., Zhou, Y., Zhang, X., Bi, L., & Chen, R. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048066 · Cited by 9 · see citing works

Functional Analysis of Rad14p, a DNA Damage Recognition Factor in Nucleotide Excision Repair, in Regulation of Transcription in Vivo

Chaurasia, P., Sen, R., & Bhaumik, S. R. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.413716 · Cited by 9 · see citing works

Urinary levels of thymine dimer as a biomarker of exposure to ultraviolet radiation in humans during outdoor activities in the summer

Liljendahl, T. S., Blomqvist, A., Andersson, E. M., Barregård, L., & Segerbäck, D. (2013) · Mutagenesis · doi:10.1093/mutage/ges077 · Cited by 9 · see citing works

XPG Asp1104His polymorphism increases colorectal cancer risk especially in Asians.

Su, J., Zhu, Y., Dai, B., Yuan, W., & Song, J. (2019) · Europe PMC (PubMed Central) · Cited by 9 · see citing works

The impact of XPC gene single nucleotide polymorphism rs2228001 on head and neck cancer patients’ response to radiotherapy treatment

Maćkowiak, B., Ostrowska, K., Kulcenty, K. I., Kaźmierska, J., Ostapowicz, J., Nowicka, H., Szewczyk, M. P., Książek, K., Suchorska, W. M., & Golusiński, W. (2024) · Reports of Practical Oncology & Radiotherapy · doi:10.5603/rpor.99676 · Cited by 8 · see citing works

Genetic Determinants of Cancer Susceptibility

Angel, J. M., Abel, E. L., & DiGiovanni, J. (2010) · Elsevier eBooks · doi:10.1016/b978-0-08-046884-6.01419-6 · Cited by 8 · see citing works

Nucleotide excision repair and human syndromes

de Boer, J., & Hoeijmakers, J. H. J. (2000) · Carcinogenesis · doi:10.1093/carcin/21.3.453 · Cited by 674 · see citing works

Global Contributions to the Understanding of DNA Repair and Skin Cancer

Kraemer, K. H., & DiGiovanna, J. J. (2014) · Journal of Investigative Dermatology · doi:10.1038/skinbio.2014.3 · Cited by 8 · see citing works

Human cancer and DNA repair-deficient diseases.

Sarasin, A. R., & Stary, A. (1997) · PubMed · Cited by 31 · see citing works

42 Deficiencies in DNA repair and its clinical impacts

Bootsma, D., Weeda, G., van der Horst, G. T. J., & Hoeijmakers, J. H. J. (1995) · European Journal of Cancer · doi:10.1016/0959-8049(95)95294-g

Nucleotide Excision Repair in Mammalian Cells

Wood, R. D. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.38.23465 · Cited by 444 · see citing works