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Neuropsychological Profile in High Functioning Autism Spectrum Disorders
Abstract
A comprehensive investigation of the neuropsychological strengths and weaknesses of children with autism may help to better describe their cognitive abilities and to design appropriate interventions. To this end we compared the NEPSY-II profiles of 22 children with high-functioning autism spectrum disorders (HFASD) with those of 44 healthy control (HC) children 2:1 matched by gender, age, race and education. Results showed that only Visuospatial Processing was relatively spared in HFASD, while deficits were observed in Attention and Executive Functions, Language, Learning and Memory, and Sensorimotor Processing. Theory of Mind difficulties were observed in verbal tasks but not in the understanding of emotional contexts, suggesting that appropriate contextual cues might help emotion understanding in HFASD children. These widespread neuropsychological impairments reflect alterations in multiple cognitive domains in HFASD.
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“Maintaining a daily routine with structured activities and being supported by the provision of specialised educational and healthcare services is of essence for children with ASD and their parents alike [64].”
From Exploring the Impact of COVID-19 on Mental Health Outcomes in Children and Adolescents: A Systematic Review (2020) · cites this paper as [64]
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“Consistent with previous reports of executive functioning deficits making ASD individuals more vulnerable to routine disruption [18], an elevated number of parents reported difficulties in managing their children’s daily activities, especially in terms of free time and structured activities.”
ResultInteractive Technologies for Autistic Children: A Review
Boucenna, S., Narzisi, A., Tilmont, E., Muratori, F., Pioggia, G., Cohen, D., & Chétouani, M. (2014) · Cognitive Computation · doi:10.1007/s12559-014-9276-x · Cited by 330
“This ability helps children to understand that other people have intentions, thoughts and emotions and act as a trigger of empathy [40, 105].”
BackgroundSelf-citationNarzisi, A. (2020) · Brain Sciences · doi:10.3390/brainsci10040207 · Cited by 299
“It is widely reported that children with ASC have executive functioning deficits [6] and they could show issues in planning their daily life activities, especially when their routine is broken.”
BackgroundSelf-citationMasini, E., Loi, E., Vega-Benedetti, A. F., Carta, M., Doneddu, G., Fadda, R., & Zavattari, P. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21218290 · Cited by 310
“ASD can be considered as a group of early-onset neuroevolutionary disorders which seem to be at the basis of alterations in brain connectivity, with cascading effects on many neuropsychological functions [1,2].”
Background
Metadata
- Authors
- Narzisi, A., Muratori, F., Calderoni, S., Fabbro, F., & Urgesi, C.
- Affiliations
- University of Pisa (IT)
- University of Udine (IT)
- Corresponding author
- Narzisi, Antonio
- Urgesi, Cosimo
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 2012-12-08
- Volume
- 43
- Issue
- 8
- Pages
- 1895-1909
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- OpenAlex
- W2034362253
- Cited by
- 126
- References
- 113
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 7 · 2023: 10 · 2022: 5 · 2021: 11 · 2020: 20 · 2019: 8 · 2018: 10 · 2017: 12 · 2016: 11 · 2015: 8 · 2014: 7 · 2013: 5
- FWCI
- 3.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- Institutional Research Information System (University of Udine) (submittedVersion)
- CINECA IRIS Institutial research information system (University of Pisa) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
- Social Sciences › Psychology › Developmental and Educational Psychology › Child and Animal Learning Development
- Keywords
- high-functioning autism, neuropsychological profile, NEPSY-II, visuospatial processing, attention deficits, executive function, language deficits, learning and memory, sensorimotor processing, theory of mind, emotional understanding, children
- MeSH terms
- Adolescent, Attention, Child, Child Development Disorders, Pervasive, Child, Preschool, Cognition Disorders, Emotions, Humans, Language, Male, Memory, Neuropsychological Tests, Psychomotor Performance, Space Perception, Executive Function, Theory of Mind
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