Autism Treatment in the First Year of Life: A Pilot Study of Infant Start, a Parent-Implemented Intervention for Symptomatic Infants
Open accessAbstract
The goal of early autism screening is earlier treatment. We pilot-tested a 12-week, low-intensity treatment with seven symptomatic infants ages 7-15 months. Parents mastered the intervention and maintained skills after treatment ended. Four comparison groups were matched from a study of infant siblings. The treated group of infants was significantly more symptomatic than most of the comparison groups at 9 months of age but was significantly less symptomatic than the two most affected groups between 18 and 36 months. At 36 months, the treated group had much lower rates of both ASD and DQs under 70 than a similarly symptomatic group who did not enroll in the treatment study. It appears feasible to identify and enroll symptomatic infants in parent-implemented intervention before 12 months, and the pilot study outcomes are promising, but testing the treatment's efficacy awaits a randomized trial.
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Early treatment may be more beneficial than treatment started at older ages.
“which research suggests may be more beneficial than treatment started at older ages.26,27,28”
From Evaluation of the Diagnostic Stability of the Early Autism Spectrum Disorder Phenotype in the General Population Starting at 12 Months (2019) · cites this paper as [28]
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Dawson, G., Rogers, S., Munson, J., Smith, M., Winter, J., Greenson, J., Donaldson, A., & Varley, J. (2010) · Pediatrics · doi:10.1542/peds.2009-0958 · Cited by 2,621 · cited 3× · see citing works
“In several ways, their improvements mirror the improvements that slightly older children make in the most efficacious interventions (Dawson et al. 2010; Lovaas 1987; Smith et al. 2000), so acceleration of developmental rates and decreased ASD symptoms resulting from early intervention should not be…”
BackgroundSelf-citationStandardizing ADOS Scores for a Measure of Severity in Autism Spectrum Disorders
Gotham, K., Pickles, A., & Lord, C. (2009) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-008-0674-3 · Cited by 1,605 · see citing works
Rogers, S. J., Estes, A., Lord, C., Vismara, L., Winter, J., Fitzpatrick, A., Guo, M., & Dawson, G. (2012) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2012.08.003 · Cited by 713 · cited 5× · see citing works
“The Infant Start 19-item parent fidelity tool (Rogers et al. 2012c) uses a Likert-based, 3-point rating system (1 = seldom present, 2 = sometimes, 3 = consistently present) associated with the six target symptoms and related parenting interventions (described above) that were the topics of the…”
InfluentialSelf-citationA randomized controlled trial of Hanen's ‘More Than Words’ in toddlers with early autism symptoms
Carter, A. S., Messinger, D. S., Stone, W. L., Celimli, S., Nahmias, A. S., & Yoder, P. (2011) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2011.02395.x · Cited by 446 · see citing works
Training parents to use the natural language paradigm to increase their autistic children's speech
Laski, K. E., Charlop, M. H., & Schreibman, L. (1988) · Journal of Applied Behavior Analysis · doi:10.1901/jaba.1988.21-391 · Cited by 316 · see citing works
Beyond Autism: A Baby Siblings Research Consortium Study of High-Risk Children at Three Years of Age
Messinger, D., Young, G. S., Ozonoff, S., Dobkins, K., Carter, A., Zwaigenbaum, L., Landa, R. J., Charman, T., Stone, W. L., Constantino, J. N., et al. (2013) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2012.12.011 · Cited by 290 · see citing works
Self-citationDawson, G., Osterling, J., Rinaldi, J., Carver, L., & McPartland, J. (2001) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1010751404865 · Cited by 73 · see citing works
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Schreibman, L., Dawson, G., Stahmer, A. C., Landa, R., Rogers, S. J., McGee, G. G., Kasari, C., Ingersoll, B., Kaiser, A. P., Bruinsma, Y., et al. (2015) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-015-2407-8 · Cited by 1,421 · see citing works
Self-citationAdvancing the understanding of autism disease mechanisms through genetics
de la Torre-Ubieta, L., Won, H., Stein, J. L., & Geschwind, D. H. (2016) · Nature Medicine · doi:10.1038/nm.4071 · Cited by 827 · see citing works
Hagerman, R. J., Berry-Kravis, E., Hazlett, H. C., Bailey, D. B., Moine, H., Kooy, R. F., Tassone, F., Gantois, I., Sonenberg, N., Mandel, J. L., et al. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.65 · Cited by 838 · see citing works
Emerson, R. W., Adams, C., Nishino, T., Hazlett, H. C., Wolff, J. J., Zwaigenbaum, L., Constantino, J. N., Shen, M. D., Swanson, M. R., Elison, J. T., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aag2882 · Cited by 359 · see citing works
Pierce, K., Gazestani, V. H., Bacon, E., Barnes, C. C., Cha, D., Nalabolu, S., Lopez, L., Moore, A., Pence-Stophaeros, S., & Courchesne, E. (2019) · JAMA Pediatrics · doi:10.1001/jamapediatrics.2019.0624 · Cited by 333 · see citing works
Green, J., Pickles, A., Pasco, G., Bedford, R., Wan, M. W., Elsabbagh, M., Slonims, V., Gliga, T., Jones, E., Cheung, C., et al. (2017) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12728 · Cited by 328 · see citing works
Constantino, J. N., & Charman, T. (2016) · The Lancet Neurology · doi:10.1016/s1474-4422(15)00151-9 · Cited by 294 · see citing works
Anxiety Disorders and Obsessive-Compulsive Disorder in Individuals with Autism Spectrum Disorder
Postorino, V., Kerns, C. M., Vivanti, G., Bradshaw, J., Siracusano, M., & Mazzone, L. (2017) · Current Psychiatry Reports · doi:10.1007/s11920-017-0846-y · Cited by 186 · see citing works
Zhou, B., Xu, Q., Li, H., Zhang, Y., Wang, Y., Rogers, S. J., & Xu, X. (2018) · Autism Research · doi:10.1002/aur.1917 · Cited by 179 · see citing works
Self-citationZwaigenbaum, L., Bryson, S. E., Brian, J., Smith, I. M., Roberts, W., Szatmari, P., Roncadin, C., Garon, N., & Vaillancourt, T. (2016) · Autism Research · doi:10.1002/aur.1585 · Cited by 165 · see citing works
Outcome Measures for Clinical Trials in Down Syndrome
Esbensen, A. J., Hooper, S. R., Fidler, D., Hartley, S. L., Edgin, J., d'Ardhuy, X. L., Capone, G., Conners, F. A., Mervis, C. B., Abbeduto, L., et al. (2017) · American Journal on Intellectual and Developmental Disabilities · doi:10.1352/1944-7558-122.3.247 · Cited by 153 · see citing works
Ozonoff, S., & Iosif, A.-M. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.03.012 · Cited by 146 · see citing works
Self-citationPierce, K., Courchesne, E., & Bacon, E. (2016) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2016.06.004 · Cited by 91 · see citing works
Early Intervention with Parents of Children with Autism Spectrum Disorders: A Review of Programs
Rojas-Torres, L. P., Alonso-Esteban, Y., & Alcantud-Marín, F. (2020) · Children · doi:10.3390/children7120294 · Cited by 73 · see citing works
“[48] followed this line of research by developing a study during the first year of life of seven children.”
BackgroundCircuits for social learning: a unified model and application to autism spectrum disorder
DeMayo, M. M., Young, L. J., Hickie, I. B., Song, Y. J. C., & Guastella, A. J. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.09.034 · Cited by 52 · see citing works
Ronconi, L., Molteni, M., & Casartelli, L. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00144 · Cited by 39 · see citing works
Minguela, N., de Valencia, U., Alcantud-Marín, F., & de Valencia, U. (2022) · Revista de Psicología y Educación - Journal of Psychology and Education · doi:10.23923/rpye2022.02.227 · Cited by 2 · see citing works
- Authors
- Rogers, S. J., Vismara, L., Wagner, A. L., McCormick, C., Young, G., & Ozonoff, S.
- Affiliations
- University of California, Davis (US)
- York University (CA)
- Corresponding author
- Rogers, S. J.
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 2014-09-12
- Volume
- 44
- Issue
- 12
- Pages
- 2981-2995
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- PMC
- PMC4951093
- OpenAlex
- W2152806460
- Cited by
- 328
- References
- 7
- Citations by year
- 2026: 10 · 2025: 14 · 2024: 12 · 2023: 11 · 2022: 25 · 2021: 38 · 2020: 39 · 2019: 36 · 2018: 39 · 2017: 39 · 2016: 31 · 2015: 28 · 2014: 5
- FWCI
- 19.16
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- Autism Speaks
- National Institute of Mental Health (R01MH068398, MH068398)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R21HD065275)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- autism spectrum disorder, early intervention, parent-mediated intervention, infant siblings, developmental quotient, treatment feasibility, low-intensity intervention
- MeSH terms
- Age Factors, Autistic Disorder, Child, Preschool, Female, Follow-Up Studies, Humans, Infant, Male, Parents, Pilot Projects, Treatment Outcome, Early Medical Intervention
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