Six-Month Outcomes from a Randomized Controlled Trial to Prevent Perinatal Depression in Low-Income Home Visiting Clients

Tandon, S. Darius; Leis, Julie A.; Mendelson, Tamar; Perry, Deborah F.; Kemp, Karen

doi:10.1007/s10995-013-1313-y

Cited by 142Maternal Mental Health During Pregnancy and PostpartumMaternal and Neonatal HealthcarePersonality Disorders and Psychopathology

Six-Month Outcomes from a Randomized Controlled Trial to Prevent Perinatal Depression in Low-Income Home Visiting Clients

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Tandon, S. Darius, Leis, Julie A., Mendelson, Tamar, Perry, Deborah F., Kemp, Karen·2014·Maternal and Child Health Journal

DOI 10.1007/s10995-013-1313-yPMC PMC3871944

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Abstract

Perinatal depression (PD) has negative consequences for mothers and children and is more prevalent among women of low socioeconomic status. Home visitation programs serve low-income pregnant women at risk for PD. This study tested the efficacy of a group-based cognitive behavioral intervention (Mothers and Babies Course; MB) in reducing depressive symptoms and preventing the onset of perinatal depression among low-income women enrolled in home visitation. A randomized controlled trial was conducted. Seventy-eight women who were pregnant or had a child less than 6 months of age and who were assessed as at risk for PD were randomized to the MB intervention or usual home visiting services. Depressive symptoms were assessed at baseline and 1-week, 3- and 6-months post-intervention; depressive episodes were assessed with a clinical interview at the 6-month follow-up. Depressive symptoms declined at a significantly greater rate for intervention participants than usual care participants between baseline and 1-week, 3 and 6 months post-intervention. At the 6-month follow-up, 15 % of women who received the MB intervention had experienced a major depressive episode as compared with 32 % of women receiving usual care. Integrating mental health interventions into home visitation appears to be a promising approach for preventing PD. Cognitive behavioral techniques can be effective in preventing depression in perinatal populations and treating it.

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Existing perinatal mental health interventions have been designed for low-risk outpatients and are not aligned with the unique needs of hospitalized antepartum patients.
“Existing perinatal mental health interventions have been designed for low‐risk outpatients [22, 23, 24, 25], and they are not aligned with the unique needs of hospitalized antepartum patients.”
From Mental health needs among patients experiencing extended antepartum hospitalization: A qualitative study (2026) · cites this paper as [22]
The citation is attached to the claim that existing interventions were designed for low-risk outpatients. The Introduction describes an earlier intervention tested among pregnant women at high risk for perinatal depression in a hospital setting, and the Discussion describes this study’s intervention for home-visitation clients at elevated risk. The sentence’s separate conclusion about hospitalized antepartum patients is not attributed to this citation. (LLM, conf=0.88)
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Existing perinatal mental health interventions have been designed for low‐risk outpatients and are not aligned with the perspectives and needs of high‐risk inpatients facing acute stressors.
“However, existing perinatal mental health interventions have been designed for low‐risk outpatients [22, 23, 24, 25]; they are not aligned with the perspectives and needs of high‐risk inpatients facing acute stressors.”
From Mental health needs among patients experiencing extended antepartum hospitalization: A qualitative study (2026) · cites this paper as [22]
The citation follows the claim that existing interventions were designed for low-risk outpatients. This paper instead studies a depression-prevention intervention for at-risk women in home-visiting programs: its Methods (Sample; page unavailable) say participants had elevated depressive symptoms or a history of depression. It does not assess whether interventions meet the needs of high-risk inpatients. (LLM, conf=0.88)
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Intervention effects on depressive symptoms and perceived stress were detected primarily at three months postpartum, consistent with previous MB trials demonstrating effects three months or later in the postpartum period.
“Intervention effects on depressive symptoms and perceived stress were detected primarily at 3 months postpartum, consistent with previous MB trials demonstrating effects 3 months or later in the postpartum period (Le et al. 2015; Tandon et al. 2014, 2022).”
From Effects of a Personalized Stress Management Intervention on Maternal Mental Health: A Randomized Clinical Trial. (2025) · cites this paper as Tandon et al. 2014
The Results report MB intervention effects on depressive symptoms at three and six months post-intervention, supporting the cited comparison with earlier MB trials. But those follow-ups are measured from the intervention, not from childbirth; the paper does not establish that they occurred three months or later postpartum. The sentence's finding about depressive symptoms and perceived stress primarily at three months appears to describe the citing authors' own study, not a finding attributed to this source. (LLM, conf=0.86)
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“May be superior to home visitation programs [104].”
Background
Substance use and depression in home visiting clients: Home visitor perspectives on addressing clients’ needs
Dauber, S. E., Ferayorni, F., Henderson, C. E., Hogue, A., Nugent, J., & Alcantara, J. (2017) · Journal of Community Psychology · doi:10.1002/jcop.21855 · Cited by 28 · see citing works
“…evidencebased mental health interventions, such as cognitive behavioral therapy and interpersonal therapy, into home visits (Ammerman et al., 2014; Gray & Price, 2014; Tandon et al., 2014) and training home visitors to implement brief behavioral health interventions (Segre et al., 2010).”
Background
Video-Delivered Family Therapy for Home Visited Young Mothers With Perinatal Depressive Symptoms: Quasi-Experimental Implementation-Effectiveness Hybrid Trial
Cluxton‐Keller, F., Williams, M., Buteau, J., Donnelly, C. L., Stolte, P., Monroe-Cassel, M., & BRUCE, M. L. (2018) · JMIR Mental Health · doi:10.2196/11513 · Cited by 27 · see citing works
“One intervention has been delivered in a group format [23] and requires mothers to travel to the location of the group.”
Implications of Comprehensive Mental Health Services Embedded in an Adolescent Obstetric Medical Home
Ashby, B. D., Ranadive, N., Alaniz, V., John‐Larkin, C. S., & Scott, S. M. (2016) · Maternal and Child Health Journal · doi:10.1007/s10995-016-1927-y · Cited by 27 · see citing works
“depression and shown to be effective [57]; and text messaging [58].”
Background
Home Visiting as an Equitable Intervention for Perinatal Depression: A Scoping Review
Tabb, K. M., Bentley, B., Piñeros-Leaño, M., Simonovich, S. D., Nidey, N., Ross, K., Huang, W. D., & Huang, H. Y. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.826673 · Cited by 24 · see citing works
“(16, 17) investigated the efficacy of a cognitive behavioral group therapy intervention in reducing depressive symptoms.”
BackgroundMethod
Culturally Sensitive Perinatal Mental Health Care: Experiences of Women From Minority Ethnic Groups
Gardner, A., Oduola, S., & Teague, B. (2024) · Health Expectations · doi:10.1111/hex.14160 · Cited by 23 · see citing works
“Furthermore, current research recommends perinatal teams work across agencies and utilise community resources [9, 31, 33], with further evidence showing that strengthening ethnic minority mothers' support networks and community connections has beneficial effects [34 – 38].”
Background
Understanding the multidimensional trajectory of psychosocial maternal risk factors causing preterm birth: A systematic review
Batra, K., Pharr, J. R., Olawepo, J. O., & Cruz, P. (2020) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2020.102436 · Cited by 23 · see citing works
Effectiveness of psychological interventions in preventing postpartum depression in non-depressed women: a systematic review and meta-analysis of randomized controlled trials
Gómez, C. M., Moreno-Peral, P., Bellón, J. Á., Cerón, S. C., Campos-Paíno, H., Gómez‐Gómez, I., Rigabert, A., Benítez, I., & Motrico, E. (2022) · Psychological Medicine · doi:10.1017/s0033291722000071 · Cited by 23 · see citing works
Results from an effectiveness-implementation evaluation of a postpartum depression prevention intervention delivered in home visiting programs
Tandon, S. D., McGown, M., Campbell, L., Smith, J. D., Yeh, C., & Brady, C. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.07.033 · Cited by 21 · see citing works
Self-citation
Comparing the Effectiveness of Clinicians and Paraprofessionals to Reduce Disparities in Perinatal Depression via the Mothers and Babies Course: Protocol for a Cluster-Randomized Controlled Trial
Jensen, J. K., Ciolino, J. D., Diebold, A., Segovia, M., Degillio, A., Solano-Martinez, J., & Tandon, S. D. (2018) · JMIR Research Protocols · doi:10.2196/11624 · Cited by 22 · see citing works
Self-citation
Comparing Fidelity Outcomes of Paraprofessional and Professional Delivery of a Perinatal Depression Preventive Intervention
Diebold, A., Ciolino, J. D., Johnson, J. K., Yeh, C., Gollan, J. K., & Tandon, S. D. (2020) · Administration and Policy in Mental Health and Mental Health Services Research · doi:10.1007/s10488-020-01022-5 · Cited by 22 · see citing works
Self-citation
Moving the dial on prenatal stress mechanisms of neurodevelopmental vulnerability to mental health problems: A personalized prevention proof of concept
Wakschlag, L. S., Tandon, D., Krogh‐Jespersen, S., Petitclerc, A., Nielsen, A., Ghaffari, R., Mithal, L., Bass, M., Ward, E., Berken, J., et al. (2021) · Developmental Psychobiology · doi:10.1002/dev.22057 · Cited by 21 · see citing works
Self-citation
Attendance at Mental Health Appointments by Women Who Were Referred During Pregnancy or the Postpartum Period
Albaugh, A. S., Friedman, S. H., Nagle-Yang, S. M., & Rosenthal, M. B. (2017) · Journal of Obstetric, Gynecologic & Neonatal Nursing · doi:10.1016/j.jogn.2017.11.001 · Cited by 21 · see citing works
Optimizing cognitive and behavioral approaches for perinatal depression: A systematic review and meta-regression analysis
Waqas, A., Zafar, S. W., Akhtar, P. S., Naveed, S., & Rahman, A. (2023) · Cambridge Prisms Global Mental Health · doi:10.1017/gmh.2023.8 · Cited by 21 · see citing works
“…Nikoo, 2019), postnatally (n= 7; Hagan et al., 2004; Milgrom et al., 2005; Graciela Rojas et al., 2007; Christine Puckering et al., 2010; Mao et al., 2012; Leung et al., 2016; Van Lieshout et al., 2022), and four during both periods (Muñoz et al., 2007; Tandon et al., 2014; Ngai et al., 2019).”
Background
Cross-Sector Approach Expands Screening and Addresses Health-Related Social Needs in Primary Care
Arbour, M. C., Floyd, B., Morton, S., Hampton, P., Sims, J. M., Doyle, S., Atwood, S., & Sege, R. (2021) · Pediatrics · doi:10.1542/peds.2021-050152 · Cited by 20 · see citing works
Effectiveness of a group intervention led by lay health workers in reducing the incidence of postpartum depression in South India
George, C., Kumar, A., & Girish, N. (2019) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2019.101864 · Cited by 20 · see citing works
A Social Media Group Cognitive Behavioral Therapy Intervention to Prevent Depression in Perinatal Youth: Stakeholder Interviews and Intervention Design
Gewali, A., Lopez, A. R., Dachelet, K., Healy, E., Jean-Baptiste, M., Harridan, H., Evans, Y. N., Unger, J. A., Bhat, A. S., Tandon, S. D., et al. (2021) · JMIR Mental Health · doi:10.2196/26188 · Cited by 17 · see citing works
“MB has been associated with a decline in depression incidence and depressive symptom severity in three randomized controlled trials and has been implemented at scale [13-17].”
BackgroundSelf-citation
A longitudinal study of the stress-buffering effect of social support on postpartum depression: a structural equation modeling approach
Yu, M., Sampson, M., Liu, Y., & Rubin, A. (2021) · Anxiety Stress & Coping · doi:10.1080/10615806.2021.1921160 · Cited by 17 · see citing works
Choosing an imbalance metric for covariate-constrained randomization in multiple-arm cluster-randomized trials
Ciolino, J. D., Diebold, A., Jensen, J. K., Rouleau, G. W., Koloms, K., & Tandon, S. D. (2019) · Trials · doi:10.1186/s13063-019-3324-5 · Cited by 16 · see citing works
Self-citation
Preventing Perinatal Depression Now: A Call to Action
Johnson, T. L., Clare, C. A., Johnson, J. E., & Simon, M. A. (2020) · Journal of Women s Health · doi:10.1089/jwh.2020.8646 · Cited by 15 · see citing works
Problem-Solving Education to Prevent Depression Among Low-Income Mothers
Silverstein, M., Cabral, H., Hegel, M. T., Díaz‐Linhart, Y., Beardslee, W. R., Kistin, C. J., & Feinberg, E. (2018) · JAMA Network Open · doi:10.1001/jamanetworkopen.2018.0334 · Cited by 14 · see citing works
Examining the Effectiveness of the Fathers and Babies Intervention: A Pilot Study
Tandon, S. D., Hamil, J. L., Gier, E. E., & Garfield, C. F. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.668284 · Cited by 15 · see citing works
Self-citation
Preventive interventions for perinatal mood and anxiety disorders: A review of selected programs
Werner, E. A., Le, H., Babineau, V., & Grubb, M. D. (2024) · Seminars in Perinatology · doi:10.1016/j.semperi.2024.151944 · Cited by 13 · see citing works
“39,40 Cultural adaptations and scaling up of the MB program have been documented for perinatal women in the US, 41,42 Spain, 43 and rural Africa, 44 suggesting that the intervention and its potential findings are highly generalizable.”
The Development and Pilot of a Technology-Based Intervention in the United States for Father’s Mental Health in the Perinatal Period
Hamil, J. L., Gier, E. E., Garfield, C. F., & Tandon, S. D. (2021) · American Journal of Men s Health · doi:10.1177/15579883211044306 · Cited by 11 · see citing works
“…to be efficacious in preventing the onset of postpartum depression and reducing depressive symptoms via multiple randomized controlled trials, (Tandon et al., 2011, 2014; S. D. Tandon et al., 2018) and was highlighted by the United States Preventive Services Task Force as one of the two most…”
BackgroundSelf-citation
Cognitive behavioral stress management effects on prenatal anxiety among low-income women.
Ponting, C., Chavira, D. A., Schetter, C. D., & Urizar, G. G. (2021) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000699 · Cited by 15 · see citing works
Could Postnatal Women’s Groups Be Used to Improve Outcomes for Mothers and Children in High-Income Countries? A Systematic Review
Sikorski, C., Hees, S. V., Lakhanpaul, M., Benton, L., Martin, J., Costello, A. M. D. L., & Heys, M. (2018) · Maternal and Child Health Journal · doi:10.1007/s10995-018-2606-y · Cited by 13 · see citing works
Integrating SMS Text Messages Into a Preventive Intervention for Postpartum Depression Delivered via In-Home Visitation Programs: Feasibility and Acceptability Study
Barrera, A. Z., Hamil, J. L., & Tandon, S. D. (2021) · JMIR Formative Research · doi:10.2196/30995 · Cited by 11 · see citing works
“MB has been examined in several controlled prevention trials, including as a face-to-face group intervention with high-risk Latina pregnant women [30,31], as a group intervention to augment HV programs [32-34], and online as a fully automated intervention, Mothers and Babies Online Course (eMB), that included an inter…”
MethodSelf-citation
Comparative effectiveness of interventions for the prevention and treatment of perinatal depression: A systematic review and network meta-analysis
Smith, R. D., Dang, W., Shen, S., Hung, S. C., Ip, H. L., Kwok, J. Y. Y., Choi, E. P. H., Fong, D., Ali, S., Wilson, C. A., et al. (2024) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2024.104316 · Cited by 13 · see citing works
Equitable reach: Patient and professional recommendations for interventions to prevent perinatal depression and anxiety
Zimmermann, M., Peacock‐Chambers, E., Merton, C., Pasciak, K., Thompson, A. B., Mackie, T. I., Clare, C. A., Lemon, S. C., & Byatt, N. (2023) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2023.10.003 · Cited by 10 · see citing works
Predictors of maternal depressive symptom trajectories over the first 18 months in home visiting.
Teeters, A. R., Ammerman, R. T., Shenk, C. E., Goyal, N. K., Folger, A. T., Putnam, F. W., & Ginkel, J. B. V. (2016) · American Journal of Orthopsychiatry · doi:10.1037/ort0000159 · Cited by 10 · see citing works
Developing and Pretesting a Survey About Immigrant Women’s Experiences With Postpartum Depression Screening
Yu, Z., Lauver, D., Wang, L., & Li, H. (2019) · Journal of Obstetric, Gynecologic & Neonatal Nursing · doi:10.1016/j.jogn.2019.01.008 · Cited by 9 · see citing works
Profile of consumers and their partners of a perinatal and infant mental health (PIMH) service in Australia
Coates, D., Saleeba, C., & Howe, D. J. (2017) · Health & Social Care in the Community · doi:10.1111/hsc.12489 · Cited by 9 · see citing works
Looking Ahead: Pre- and Perinatal Interventions for Maternal Distress to Prevent Neurodevelopmental Vulnerability
Brown, H., Krogh-Jespersen, S., Tandon, D., Graham, A., Mackiewicz Seghete, K., & Wakschlag, L. (2021) · Prenatal Stress and Child Development · doi:10.1007/978-3-030-60159-1_20 · Cited by 13 · see citing works
Self-citation
Study protocol for the ROSE Scale-Up Study: Informing a decision about ROSE as universal postpartum depression prevention
Johnson, J. E., Loree, A. M., Sikorskii, A. E., Miller, T. R., Carravallah, L. A., Taylor, B., & Zlotnick, C. (2023) · Contemporary Clinical Trials · doi:10.1016/j.cct.2023.107297 · Cited by 8 · see citing works
Digital Support Systems to Improve Child Health and Development in Peru: Protocol for a Randomized Controlled Trial
Hartinger, S. M., Mäusezahl, D., Jäggi, L., Aguilar, L., Alvarado, M., Castellanos, A., Bustamante, M. L. H., Hinckley, K., McCoy, D. C., Zhang, C., et al. (2023) · JMIR Research Protocols · doi:10.2196/50371 · Cited by 9 · see citing works
“Despite consistently positive impacts on maternal [19,20] and child well-being [21,22], most countries have not adopted home visiting programs at scale due to the high cost and logistical efforts associated with them.”
Background
Comparing the effectiveness of mother-focused interventions to that of mother-child focused interventions in improving maternal postpartum depression outcomes: A systematic review
Kumar, D., Hameed, W., & Avan, B. I. (2023) · PLoS ONE · doi:10.1371/journal.pone.0295955 · Cited by 10 · see citing works
“Allocation concealment was adequately done (i.e., consecutively-numbered, sealed, opaque envelopes containing randomly-generated numbers) in 11 studies [10, 44, 46–49, 51, 53–56] while it was unclear in 13 studies [57, 63–71 , 74– 76].”
BackgroundMethodResultInfluential
Engaging rural young mothers in a technology-based intervention for depression
Cluxton‐Keller, F., Buteau, J., Williams, M., Stolte, P., Monroe-Cassel, M., & BRUCE, M. L. (2019) · Child & Youth Services · doi:10.1080/0145935x.2018.1561264 · Cited by 8 · see citing works
“in other research studies of interventions for depressed home visited mothers (e.g., Ammerman et al., 2013; Beeber et al., 2010; Silverstein et al., 2017; Tandon et al., 2014), the mothers in the current study faced a greater number of logistical barriers because they live in highly rural communities and most do not h…”
Result
Factors impacting attrition of vulnerable women from a longitudinal mental health intervention study
Doornbos, M. M., Zandee, G. L., Timmermans, B., Moes, J., Heitsch, E., Quist, M., Heetderks, E., Houskamp, C., & VanWolde, A. (2019) · Public Health Nursing · doi:10.1111/phn.12687 · Cited by 8 · see citing works
A Non-Randomized Controlled Trial for Reducing Postpartum Depression in Low-Income Minority Women at Community-Based Women’s Health Clinics
Alfayumi‐Zeadna, S., Zeadna, A., Azbarga, Z., Salman, L., Froimovici, M., Alkatnany, A., Grotto, I., & Daoud, N. (2022) · Maternal and Child Health Journal · doi:10.1007/s10995-022-03434-1 · Cited by 8 · see citing works
“Interventions that targeted minority and low-income mothers in the US and included social support, PPD awareness, management skills, access to resources, and guidance on healthy lifestyle found that the intervention groups experienced significant declines in PPD (Howell et al., 2012; Tandon et al., 2014).”
Background
A Mixed-Methods Evaluation of Virtually Delivered Group-Based Mothers and Babies for Latina Immigrant Mothers
Platt, R. E., Martin, C. P., Perry, O., Cooper, L., Tandon, S. D., Richman, R., Bettencourt, A. F., & Polk, S. (2023) · Women s Health Issues · doi:10.1016/j.whi.2023.05.005 · Cited by 7 · see citing works
Self-citation
Integrating Mental Health Care in Ambulatory Obstetrical Practices: Strategies and Models
Bell, K., Ashby, B. D., Scott, S., & Poleshuck, E. L. (2024) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0000000000000841 · Cited by 7 · see citing works
Transitioning to No Poverty
Günther, I., & Lahoti, R. (2021) · MDPI eBooks · doi:10.3390/books978-3-03897-861-9 · Cited by 7 · see citing works
ADDRESSING SUBSTANCE‐USE PROBLEMS IN TRIBAL HOME VISITING
Novins, D. K., Ferron, C., Abramson, L., & Barlow, A. (2018) · Infant Mental Health Journal · doi:10.1002/imhj.21706 · Cited by 7 · see citing works
Reproductive Justice Interventions in Pregnancy: Moving Toward Improving Black Maternal Perinatal and Intergenerational Mental Health Outcomes
Dreux, S., Ramsey, N. L. M., Gissandaner, T. D., Alarcon, N., & Duarte, C. S. (2025) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000424 · Cited by 6 · see citing works
Acceptability and Utility of a Digital Group Intervention to Prevent Perinatal Depression in Youths via Interactive Maternal Group for Information and Emotional Support (IMAGINE): Pilot Cohort Study
Ronen, K., Gewali, A., Dachelet, K., White, E., Jean-Baptiste, M., Evans, Y. N., Unger, J. A., Tandon, S. D., & Bhat, A. S. (2023) · JMIR Formative Research · doi:10.2196/51066 · Cited by 6 · see citing works
“These questions were modeled on the core CBT components of the MB program [17].”
MethodSelf-citation
Home-Based Early Head Start plus Attachment and Biobehavioral Catch-up: A Qualitative Study of Implementation Outcomes
West, A. L., Berlin, L. J., Goodman, A., Endy, K., Manzon, C., & Harden, B. J. (2022) · Journal of Child and Family Studies · doi:10.1007/s10826-021-02189-7 · Cited by 7 · see citing works
The impact of telemental health interventions on maternal mental health outcomes: a pilot randomized controlled trial during the COVID-19 pandemic
Naja, S., Elyamani, R., Chehab, M. A. H., Ahmed, M. A. S., Babeker, G., Lawand, G., Singh, R., Adli, N., Mohamad, T., & Bougmiza, I. M. (2022) · Health Psychology and Behavioral Medicine · doi:10.1080/21642850.2022.2155167 · Cited by 6 · see citing works
“To specify, a short-term group-based CBT revealed a signi ﬁ cant decline in antenatal depressive scores in the intervention arm compared with receiving usual care after three weeks of follow-up (Tandon et al., 2014).”
Method
A latent class analysis of brief postpartum psychiatric hospital admissions
Polachek, I. S., Fung, K., Putnam, K. T., Meltzer-Brody, S. E., & Vigod, S. N. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.09.023 · Cited by 6 · see citing works
“There may be an even greater opportunity to prevent admissions in women with histories of non-psychotic mental illnesses such as those in Class 3, since their illnesses may progress more insidiously(O'Connor et al., 2016; Tandon et al., 2014).”
Can an evidence-based mental health intervention be implemented into preexisting home visiting programs using implementation facilitation? Study protocol for a three variable implementation effectiveness context hybrid trial
Faro, E. Z., Jones, D., Adeagbo, M. J., Cho, H., Swartzendruber, G., Tabb, K. M., Tandon, S. D., & Ryckman, K. K. (2024) · Implementation Science · doi:10.1186/s13012-024-01402-7 · Cited by 5 · see citing works
“The most recent of these trials assessed the MB intervention one-on-one as delivered by trained lay health workers conducted in the setting of HVPs [18, 21–24].”
BackgroundSelf-citation
Evaluating Culturally Tailored Strategies for Implementing Cognitive Interviewing on Edinburgh Postnatal Depression Scale Among Chinese Immigrant Women
Yu, Z., Jin, Y., & Lor, M. (2020) · Journal of Transcultural Nursing · doi:10.1177/1043659620950437 · Cited by 5 · see citing works
“PPD affects one in seven women worldwide (Stewart & Vigod, 2016); however, less than half are recognized and treated (Pooler et al., 2013; Tandon et al., 2014).”
Background
Evaluation of a Home Visiting Program
Lowe, K., Cartagena, D. C., & Gudger, K. (2021) · Home Healthcare Now · doi:10.1097/nhh.0000000000000948 · Cited by 5 · see citing works
Personalized Mobile Health-Enhanced Cognitive Behavioral Intervention for Maternal Distress: Examining the Moderating Role of Adverse Childhood Experiences
Goldstein, E., Merrick, J., Edwards, R. C., Zhang, Y., Sinche, B., Raven, J. G., Krislov, S., Robledo, D., Brown, R., Moskowitz, J. T., et al. (2024) · The Permanente Journal · doi:10.7812/tpp/23.094 · Cited by 4 · see citing works
“18,24 This novel intervention was designed to support and encourage pregnant and postpartum individuals to engage in enjoyable activities, adopt healthy thought patterns, seek social support, and practice mindfulness, in addition to developing and strengthening the parental bond with the baby.”
BackgroundSelf-citation
Examining Feasibility, Acceptability, and Preliminary Outcomes of a Culturally Adapted Evidence-Based Postpartum Depression Preventive Intervention for Women in Doha, Qatar: Protocol for a Randomized Controlled Trial
Ahmed, S. R., Watt, F., Mahfoud, Z. R., Korayem, M., Buhmaid, S., Alberry, M., Ibrahim, I., & Tandon, S. D. (2023) · JMIR Research Protocols · doi:10.2196/11623 · Cited by 4 · see citing works
Self-citation
Opportunities and Challenges in Addressing Maternal Depression in Community Settings
Ammerman, R. T. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.1173 · Cited by 4 · see citing works
Acceptability and appropriateness of a perinatal depression preventive group intervention: a qualitative analysis
Diebold, A., Segovia, M., Johnson, J. K., Degillio, A., Zakieh, D., Park, H., Lim, K., & Tandon, S. D. (2020) · BMC Health Services Research · doi:10.1186/s12913-020-5031-z · Cited by 4 · see citing works
Self-citation
Variation of Behavioral Health Care by Behavioral Health Symptom Profile Among a Diverse Group of Pregnant and Parenting Mothers
Weiss‐Laxer, N. S., Johnson, S. B., & Riley, A. W. (2020) · The Journal of Behavioral Health Services & Research · doi:10.1007/s11414-020-09701-9 · Cited by 4 · see citing works
Reducing depression among mothers in a residential treatment setting: building evidence for the PST4PPD intervention
Sampson, M., Mauldin, R. L., & Yu, M. (2020) · Social Work in Mental Health · doi:10.1080/15332985.2020.1832644 · Cited by 4 · see citing works
Direct and indirect predictors of postpartum depression symptoms among indigenous Bedouin mothers in Israel
Alfayumi‐Zeadna, S., Ghalion, H. A., O’Rourke, N., Azbarga, Z., & Daoud, N. (2023) · Research in Nursing & Health · doi:10.1002/nur.22361 · Cited by 4 · see citing works
Global Absolute Poverty: The Beginning of the End?
Reddy, S. G. (2020) · MDPI eBooks · doi:10.2139/ssrn.3537705 · Cited by 4 · see citing works
Postpartum Depression: Far Reaching Impact and the Role of Empowerment
King, C. R., Morgan, S. M., Firebaugh, C. M., Beeson, T., Legg, T. J., & Wardlow, R. (2021) · Open Journal of Depression · doi:10.4236/ojd.2021.102003 · Cited by 3 · see citing works
Mothers and Babies Virtual Group (MBVG) for perinatal Latina women: study protocol for a hybrid type-1 effectiveness-implementation randomized controlled trial
Platt, R. E., Polk, S., Barrera, A. Z., Lara-Cinisomo, S., Hirschhorn, L. R., Graham, A. K., Musci, R. J., Hamil, J. L., Echavarria, D. M., Cooper, L., et al. (2024) · Trials · doi:10.1186/s13063-024-08423-z · Cited by 3 · see citing works
“Covariates will be finalized in a Statistical Analysis Plan but based on our prior studies [80, 87] will include (1) whether participant is a first-time mother (e.g., current number of children = 0 at baseline; (2) education (at least some high school vs less than high school); (3) mental health…”
MethodSelf-citation
Effect of Cognitive Behavioral Therapy (CBT) for Perinatal Depression: A Systematic Review and Meta-Analysis
Shin, H.-H., Shin, Y., & Kim, G. (2016) · Journal of the Korea Academia-Industrial cooperation Society · doi:10.5762/kais.2016.17.11.271 · Cited by 3 · see citing works
Maternal Self-Care, Attachment Style, and Observed Parenting in a Preschool Sample with Autism Spectrum Disorder
Johnson, M. L. (2019) · doi:10.7916/d8-31zp-r754 · Cited by 3 · see citing works
Implementation cost analysis of collaborative care for perinatal mental health in community health centersPreprint
Grover, T., Bennett, I. M., Campbell, M. R., Vredevoogd, M. A., & Saldana, L. (2024) · Research Square · doi:10.21203/rs.3.rs-5256122/v1 · Cited by 3 · see citing works
Mental health needs among patients experiencing extended antepartum hospitalization: A qualitative study
Goulding, A. N., Ibarra, M., Cirino, N., Miller, E. S., & Fletcher, T. L. (2026) · Pregnancy · doi:10.1002/pmf2.70229 · Cited by 2 · see citing works
“For example, the two most widely used programs for preventing perinatal depression, the cognitive behavioral therapy (CBT)-based Mothers and Babies [22, 23] program and the inter-personal psychotherapy–based Reach Out, Stand Strong, Essentials for New Mothers (ROSE) [24, 25] program, are…”
Effects of a Personalized Stress Management Intervention on Maternal Mental Health: A Randomized Clinical Trial.
Tandon, S. D., Moskowitz, J. T., Edwards, R. C., Zhang, Y., Giase, G., Sinche, B., Blum, A. L., Krislov, S., Reynolds, H. M., Rangarajan, A., et al. (2025) · Archives of Women's Mental Health · doi:10.1007/s00737-025-01619-5 · Cited by 3 · see citing works
“Intervention effects on depressive symptoms and per - ceived stress were detected primarily at 3 months post-partum, consistent with previous MB trials demonstrating effects 3 months or later in the postpartum period (Le et al. 2015 ; Tandon et al. 2014 , 2022 ).”
Self-citation
Integrating mental health into obstetric practice: a review of collaborative care models for perinatal anxiety
Dewantiningrum, J., Andonotopo, W., Lukas, E., Pramono, M. B. A., Prabowo, W., Bachnas, M. A., Sanjaya, I. N. H., Wiradnyana, A. A. G. P., Kusuma, A. A. N. J., Gumilar, K. E., et al. (2025) · Journal of Perinatal Medicine · doi:10.1515/jpm-2025-0300 · Cited by 2 · see citing works
“Singla et al. [61] and Tandon et al. [64] demonstrated that non-specialists can deliver e ﬀ ective ﬁ rst-line interventions when trained and supervised under collaborative structures.”
Influential
Development and feasibility of a Configurable Assessment Messaging Platform for Interventions (CAMPI).
Bass, M., Rosen, K. D., Gerend, M. A., Wakschlag, L. S., Madkins, K., Crosby, S. T., Alshurafa, N. I., King, Z., Ghaffari, R., & Smith, J. D. (2021) · Families Systems & Health · doi:10.1037/fsh0000592 · Cited by 2 · see citing works
“Wellness-4-2 is an adapation of the Mothers and Babies perinatal depression prevention intervention (Tandon et al., 2011, 2014) designed to reduce maternal distress during pregnancy and reduce adverse impact on infant neurodevelopment (Wakschlag et al., 2020).”
Background
The Happy Child Program’s Intersectionality: Prenatal Home Visit Frequency, Food Insecurity Risk, Symptoms of Depression, and Parental Practices in Brazilian Women Assisted during Pregnancy
Biete, C., Gonçalves, V. S. S., do Carmo, A. S., & Pizato, N. (2024) · Nutrients · doi:10.3390/nu16172990 · Cited by 2 · see citing works
“Additionally, longitudinal studies to assess the long-term effects of home visits on the mental health of pregnant women in socially vulnerable situations need to be conducted.”
Background
Virtual versus in-person ROSE program (La Luz) as universal prevention for perinatal depression: Protocol for a randomized controlled trial in a safety net hospital
Liu, D. Y., Perry, N. S., Demers, C. H., Hyer, J., Alamo, A., Vuksanovich, P., Dube, N., Flanagan, E. R., Gallop, R., RHOADES, G. K., et al. (2025) · Contemporary Clinical Trials · doi:10.1016/j.cct.2025.107988 · Cited by 2 · see citing works
“Although several perinatal depression interventions have shown efficacy in reducing depression during pregnancy [21,22] and postpartum [23–25], it is critical to increase their reach to communities in need, particularly those at elevated risk for perinatal depression and those who experience…”
The effects of depressive symptom management interventions on low‐income mothers: A systematic review and meta‐analysis
Kim, K., & Lee, Y. (2018) · Journal of Advanced Nursing · doi:10.1111/jan.13912 · Cited by 2 · see citing works
A Safety Net for You, A Safety Net for Me? Donor Promotion of Social Protection Schemes Faces Policy Coherence Issues
Brugger, F. (2021) · MDPI eBooks · doi:10.3390/books978-3-03897-861-9-12 · Cited by 1 · see citing works
Infant and Early Childhood Home Visiting
McKelvey, L. M., Cook, G. A., Hughes‐Belding, K., & Fitzgerald, H. E. (2024) · Springer eBooks · doi:10.1007/978-3-031-48631-9_27 · Cited by 1 · see citing works

Preventing perinatal depression in low-income home visiting clients: A randomized controlled trial.
Tandon, S. D., Perry, D. F., Mendelson, T., Kemp, K., & Leis, J. A. (2011) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0024895 · Cited by 105 · see citing works
Self-citation
Perinatal depression prevention through home visitation: a cluster randomized trial of mothers and babies 1-on-1
Tandon, S. D., Ward, E. A., Hamil, J. L., Jimenez, C., & Carter, M. (2018) · Journal of Behavioral Medicine · doi:10.1007/s10865-018-9934-7 · Cited by 62 · see citing works
Self-citation
Comparing the Effectiveness of Clinicians and Paraprofessionals to Reduce Disparities in Perinatal Depression via the Mothers and Babies Course: Protocol for a Cluster-Randomized Controlled Trial
Jensen, J. K., Ciolino, J. D., Diebold, A., Segovia, M., Degillio, A., Solano-Martinez, J., & Tandon, S. D. (2018) · JMIR Research Protocols · doi:10.2196/11624 · Cited by 22 · see citing works
Self-citation
An Open Trial of In-Home CBT for Depressed Mothers in Home Visitation
Ammerman, R. T., Putnam, F. W., Stevens, J. H., Bosse, N. R., Short, J. A., Bodley, A. L., & Ginkel, J. B. V. (2010) · Maternal and Child Health Journal · doi:10.1007/s10995-010-0691-7 · Cited by 48 · see citing works
Preventing perinatal depression in Spain: a pilot evaluation of Mamás y Bebés
Le, H., Muñoz, M. D. L. F. R., Balbuena, C. S., Crespo, M. E. O., Méndez, N. I., & Marcos-Nájera, R. (2019) · Journal of Reproductive and Infant Psychology · doi:10.1080/02646838.2019.1687859 · Cited by 7 · see citing works

Authors: Tandon, S. D., Leis, J. A., Mendelson, T., Perry, D. F., & Kemp, K.
Affiliations: Johns Hopkins University (US)
Georgetown University (US)
Corresponding author: Tandon, S. Darius
ORCID: Tandon, S. Darius
Leis, Julie A.
Mendelson, Tamar
Perry, Deborah F.
Venue: Maternal and Child Health Journal
Publisher: Springer Science and Business Media LLC
Published: 2013-06-22
Volume: 18
Issue: 4
Pages: 873-881
ISSN: 1092-7875 (ISSN-L)
1573-6628
DOI: 10.1007/s10995-013-1313-y
PMC: PMC3871944
OpenAlex: W1974464317
Cited by: 142
References: 40
Citations by year: 2026: 8 · 2025: 6 · 2024: 14 · 2023: 18 · 2022: 18 · 2021: 25 · 2020: 13 · 2019: 9 · 2018: 11 · 2017: 8 · 2016: 7 · 2015: 3 · 2014: 2
FWCI: 4.09
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.springer.com/tdm (tdm)
Locations: Maternal and Child Health Journal (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (UL1TR001079, UL1TR000424)
National Center for Research Resources (UL1RR025005)
National Center for Advancing Translational Sciences
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords: perinatal depression, depression prevention, home visits, low-income pregnant women, cognitive-behavioral intervention, group intervention, maternal mental health, socioeconomic status, maternal depression
MeSH terms: Adolescent, Adult, Female, Follow-Up Studies, House Calls, Humans, Infant, Infant, Newborn, Male, Maternal Age, Postnatal Care, Poverty, Pregnancy, Severity of Illness Index, Time Factors, Urban Population, Cognitive Behavioral Therapy, Linear Models, Treatment Outcome, Risk Assessment, Home Care Agencies, Depression, Postpartum, Young Adult

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Six-Month Outcomes from a Randomized Controlled Trial to Prevent Perinatal Depression in Low-Income Home Visiting Clients

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