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Cited by 494Maternal Mental Health During Pregnancy and PostpartumMaternal and Neonatal HealthcareMaternal and Perinatal Health Interventions

Interventions to Prevent Perinatal Depression: US Preventive Services Task Force Recommendation Statement

US Preventive Services Task Force, Curry, Susan J., Krist, Alex H., Owens, Douglas K., Barry, Michael J., Caughey, Aaron B., Davidson, Karina W., Doubeni, Chyke A. +10 more·2019·JAMA
DOI 10.1001/jama.2019.0007
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Abstract

Importance: Perinatal depression, which is the occurrence of a depressive disorder during pregnancy or following childbirth, affects as many as 1 in 7 women and is one of the most common complications of pregnancy and the postpartum period. It is well established that perinatal depression can result in adverse short- and long-term effects on both the woman and child. Objective: To issue a new US Preventive Services Task Force (USPSTF) recommendation on interventions to prevent perinatal depression. Evidence Review: The USPSTF reviewed the evidence on the benefits and harms of preventive interventions for perinatal depression in pregnant or postpartum women or their children. The USPSTF reviewed contextual information on the accuracy of tools used to identify women at increased risk of perinatal depression and the most effective timing for preventive interventions. Interventions reviewed included counseling, health system interventions, physical activity, education, supportive interventions, and other behavioral interventions, such as infant sleep training and expressive writing. Pharmacological approaches included the use of nortriptyline, sertraline, and omega-3 fatty acids. Findings: The USPSTF found convincing evidence that counseling interventions, such as cognitive behavioral therapy and interpersonal therapy, are effective in preventing perinatal depression. Women with a history of depression, current depressive symptoms, or certain socioeconomic risk factors (eg, low income or young or single parenthood) would benefit from counseling interventions and could be considered at increased risk. The USPSTF found adequate evidence to bound the potential harms of counseling interventions as no greater than small, based on the nature of the intervention and the low likelihood of serious harms. The USPSTF found inadequate evidence to assess the benefits and harms of other noncounseling interventions. The USPSTF concludes with moderate certainty that providing or referring pregnant or postpartum women at increased risk to counseling interventions has a moderate net benefit in preventing perinatal depression. Conclusions and Recommendation: The USPSTF recommends that clinicians provide or refer pregnant and postpartum persons who are at increased risk of perinatal depression to counseling interventions. (B recommendation).

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Authors
US Preventive Services Task Force, Curry, S. J., Krist, A. H., Owens, D. K., Barry, M. J., Caughey, A. B., Davidson, K. W., Doubeni, C. A., Epling, J. W., Grossman, D. C., Kemper, A. R., Kubik, M., Landefeld, C. S., Mangione, C. M., Silverstein, M., Simon, M. A., Tseng, C.-W., & Wong, J. B.
Affiliations
  • University of Iowa (US)
  • Virginia Commonwealth University (US)
  • Harvard University (US)
  • Northwell Health (US)
  • Carilion Clinic (US)
  • Kaiser Permanente Washington Health Research Institute (US)
  • Nationwide Children's Hospital (US)
  • University of Alabama at Birmingham (US)
  • University of California, Los Angeles (US)
  • Boston University (US)
  • Northwestern University (US)
  • University of Hawaiʻi at Mānoa (US)
  • Tufts University (US)
Corresponding author
Curry, Susan J.
ORCID
Venue
JAMA
Publisher
American Medical Association (AMA)
Published
2019-02-12
Volume
321
Issue
6
Pages
580
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
DOI
10.1001/jama.2019.0007
OpenAlex
W2912060701
Cited by
494
References
54
Citations by year
2026: 50 · 2025: 66 · 2024: 72 · 2023: 65 · 2022: 68 · 2021: 78 · 2020: 66 · 2019: 29
FWCI
55.46
Type
journal article
Language
en
Open access
closed
Locations
  • JAMA (publishedVersion)
  • PubMed (publishedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
  • Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
  • Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
Keywords
perinatal depression, depression prevention, pregnancy, postpartum period, counseling intervention, cognitive behavioral therapy, interpersonal psychotherapy, risk assessment tools, nortriptyline, sertraline, omega-3 fatty acids, infant sleep training, expressive writing, physical activity, maternal mental health
MeSH terms
Antidepressive Agents, Counseling, Depression, Female, Humans, Pregnancy, Pregnancy Complications, Referral and Consultation, Risk Factors, Cognitive Behavioral Therapy, Risk Assessment, Depression, Postpartum

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