The association between air pollutants and autism spectrum disorders
Abstract
Autism spectrum disorders are a member of the pervasive developmental disorders (PDDs) that have been increasing dramatically since described by Leo Kanner in 1943. In the past decade, the number of epidemiological publications addressing air pollution exposures and autism has grown correspondingly, but the association is still unclear. Whether air pollutants play a causal role and which substances are related with autism requires further study. We systematically reviewed the literature from 2005 to 2016 in MEDLINE (National Library of Medicine), Web of Science, and PubMed and summarized the association between different air pollutants and autism. Furthermore, we further discussed the exposure time window and potential confounders that should be considered in the association analysis studies. Our objective is to summarize the association between different air pollutants and autism with literature, which has been published since 2005, and explore whether the exposure time window and potential confounders have influence on this association. These results could provide more comprehensive information about the association between air pollutants and autism and be helpful towards further validation study. Graphical abstract ᅟ.
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There is a growing body of literature documenting an association between airborne pollutants and ASD, summarized in several reviews.
“There is a growing body of literature documenting the association between airborne pollutants and ASD, with epidemiological studies undertaken during the last decade recently summarized in several reviews [185, 186].”
From The contribution of environmental exposure to the etiology of autism spectrum disorder (2019) · cites this paper as [186]
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- Authors
- Yang, C., Zhao, W., Deng, K., Zhou, V., Zhou, X., & Hou, Y.
- Affiliations
- Harbin Medical University (CN)
- University of Washington (US)
- Corresponding author
- Hou, Yan
- Venue
- Environmental Science and Pollution Research
- Published
- 2017-05-24
- Volume
- 24
- Issue
- 19
- Pages
- 15949-15958
- ISSN
- 0944-1344 (ISSN-L)
- 1614-7499
- OpenAlex
- W2619660526
- Cited by
- 32
- References
- 63
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 4 · 2023: 2 · 2022: 4 · 2021: 6 · 2020: 2 · 2019: 4 · 2018: 7
- FWCI
- 2.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Environmental Science and Pollution Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- the National Natural Science Foundation of China (81573256)
- The Youth Innovation Training Program of Heilongjiang province (UNPYSCT-2016048)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Health, Environment, Cognitive Aging
- Keywords
- autism spectrum disorder, air pollution, environmental exposure, exposure time window, confounding factors, prenatal exposure, pervasive developmental disorders, environmental risk factors
- MeSH terms
- Autism Spectrum Disorder, Air Pollutants, Air Pollution, Female, Humans, Pregnancy, Prenatal Exposure Delayed Effects
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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