Cited by 142

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Design of aging intervention studies: the NIA interventions testing program

Nadon, N. L., Strong, R., Miller, R. A., Nelson, J., Javors, M., Sharp, Z. D., Peralba, J. M., Harrison, D. E.·2008·AGE

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1007/s11357-008-9048-1

Cites

7 of 7 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The enteric coating increased the fraction of rapamycin that survived food preparation by 3- to 4-fold and protected the agent from digestion in the stomach.

    “This coating increased the fraction of rapamycin that survived the food preparation process by 3- to 4-fold, and protected the agent from digestion in the stomach16.”
  • The National Institute on Aging Interventions Testing Program (ITP) evaluates agents that may delay ageing and increase lifespan in genetically heterogeneous mice.

    “The National Institute on Aging Interventions Testing Program (ITP) evaluates agents that may delay ageing and increase lifespan in genetically heterogeneous mice15–17.”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 74

  1. Ahotupa M, Bereziat JC, Mantyla E, Bartsch H (1993) Dietary fat- and phenobarbital-induced alterations in hepatic antioxidant functions in mice. Carcinogenesis 14:1225–1228 · DOI
  2. Baur JA, Sinclair DA (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 5:493–506 · DOI · Paper page
  3. Bhimani RS, Troll W, Grunberger D, Frenkel K (1993) Inhibition of oxidative stress in HeLa cells by chemopreventive agents. Cancer Res 53:4528–4533
  4. Blackwell BN, Bucci TJ, Hart RW, Turturro A (1995) Longevity, body weight, and neoplasia in ad libitum-fed and diet-restricted C57BL/6 mice fed NIH-31 open formula diet. Toxicol Pathol 23:570–582 · DOI · Paper page
  5. Bonetti PO, Lerman LO, Napoli C, Lerman A (2003) Statin effects beyond lipid lowering—are they clinically relevant? Eur Heart J 24:225–248 · DOI
  6. Borrelli F, Maffia P, Pinto L, Ianaro A, Russo A, Capasso F, Ialenti A (2002) Phytochemical compounds involved in the anti-inflammatory effect of propolis extract. Fitoterapia 73(Suppl 1):S53–63 · DOI
  7. Bronson RT, Lipman RD (1991) Reduction in rate of occurrence of age related lesions in dietary restricted laboratory mice. Growth Dev Aging 55:169–184
  8. Brunelli S, Sciorati C, D’Antona G, Innocenzi A, Covarello D, Galvez BG, Perrotta C, Monopoli A, Sanvito F, Bottinelli R, Ongini E, Cossu G, Clementi E (2007) Nitric oxide release combined with nonsteroidal antiinflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy. Proc Natl Acad Sci USA 104:264–269 · DOI
  9. Buu-Hoi NP, Ratsimamanga AR (1959) Retarding action of nordihydroguiaiaretic acid on aging in the rat (in French). C R Seances Soc Biol 153:1180–1182
  10. Caballero F, Gerez E, Batlle A, Vazquez E (2000) Preventive aspirin treatment of streptozotocin induced diabetes: blockage of oxidative status and revertion of heme enzymes inhibition. Chemico-Biol Interac 126:215–225 · DOI
  11. Campen MJ, Tagaito Y, Jenkins TP, Smith PL, Schwartz AR, O’Donnell CP (2002) Phenotypic differences in the hemodynamic response during REM sleep in six strains of inbred mice. Physiol Genom 11:227–234 · DOI
  12. Carter CS, Cesari M, Justice JF, Hu N, Ambrosius W, Diz D, Oden S, Pahor M (2002) ACE inhibition, body composition and physical performance in aged rats. J Gerontol A Biol Sci Med Sci 57:B193–B197 · DOI · Paper page
  13. Chen Y, Tseng SH, Lai HS, Chen WJ (2004) Resveratrol-induced cellular apoptosis and cell cycle arrest in neuroblastoma cells and antitumor effects on neuroblastoma in mice. Surgery 136:57–66 · DOI
  14. de Cavanagh EM, Fraga CG, Ferder L, Inserra F (1997) Enalapril and captopril enhance antioxidant defenses in mouse tissues. Am J Physiol 272:R514–R518
  15. de Cavanagh EM, Ferder L, Carrasquedo F, Scrivo D, Wassermann A, Fraga CG, Inserra F (1999) Higher levels of antioxidant defenses in enalapril-treated versus non-enalapril-treated hemodialysis patients. Am J Kidney Dis 34:445–55 · DOI
  16. Edamatsu R, Mori A, Packer L (1995) The spin-trap N-tert-alpha-phenyl-butylnitrone prolongs the life span of the senescence accelerated mouse. Biochem Biophys Res Commun 211:847–849 · DOI
  17. Ferder L, Daccordi H, Martello M, Panzalis M, Inserra F (1992) Angiotensin converting enzyme inhibitors versus calcium antagonists in the treatment of diabetic hypertensive patients. Hypertension 19:II237–II242 · DOI
  18. Ferder L, Inserra F, Romano L, Ercole L, Pszenny V (1994) Decreased glomerulosclerosis in aging by angiotensin-converting enzyme inhibitors. J Am Soc Nephrol 5:1147–52 · DOI
  19. Fernandes G, Yunis EJ, Good RA (1976) Influence of diet on survival of mice. Proc Natl Acad Sci USA 73:1279–1283 · DOI
  20. Floyd RA (1990) Role of oxygen free radicals in carcinogenesis and brain ischemia. FASEB J 4:2587–2597 · DOI
  21. Floyd RA, Kotake Y, Hensley K, Nakae D, Konishi Y (2002) Reactive oxygen species in choline deficiency induced carcinogenesis and nitrone inhibition. Mol Cell Biochem 234-235(1–2):195–203 · DOI
  22. Frenkel K, Wei H, Bhimani RS, Ye J, Zadunaisky JA, Huang MT, Ferraro T, Conney AH, Grunberger D (1993) Inhibition of tumor promoter-mediated processes in mouse skin and bovine lens by caffeic acid phenethyl ester. Cancer Res 53:1255–1261
  23. Gambassi G, Lapane KL, Sgadari A, Carbonin P, Gatsonis C, Lipsitz LA, Mor V, Bernabei R (2000) Effects of angiotensin-converting enzyme inhibitors and digoxin on health outcomes of very old patients with heart failure. SAGE Study Group. Systematic Assessment of Geriatric drug use via Epidemiology. Arch Intern Med 160:53–60 · DOI
  24. Garber K (2001) Rapamycin’s resurrection: a new way to target the cancer cell cycle. J Natl Cancer Inst 93:1517–1519 · DOI · Paper page
  25. Goodrick CL, Ingram DK, Reynolds MA, Freeman JR, Cider N (1990) Effects of intermittent feeding upon body weight and lifespan in inbred mice: interaction of genotype and age. Mech Ageing Dev 55:69–87 · DOI · Paper page
  26. Guba M, von Breitenbuch P, Steinbauer M, Koehl G, Flegel S, Hornung M, Bruns CJ, Zuelke C, Farkas S, Anthuber MM, Jauch KW, Geissler EK (2002) Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. Nat Med 8:128–135 · DOI
  27. Harper JM, Galecki AT, Burke DT, Pinosky SL, Miller RA (2003) Quantitive trait loci for insulin-like growth factor I, leptin, thyroxine, and corticosterone in genetically heterogeneous mice. Physiol Gen 15:44–51 · DOI
  28. Harper JM, Galecki AT, Burke DT, Miller RA (2004) Body weight, hormones and T cell subsets as predictors of life span in genetically heterogeneous mice. Mech Ageing Dev 125:381–390 · DOI
  29. Harrison, D, Archer JR, Kent B (1991) Genes regulate effects of dietary restriction. In: Fishbein L (ed) Biological effects of dietary restriction. Springer, New York, pp 264–286 · DOI
  30. Ikeno Y, Hubbard GB, Lee S, Richardson A, Strong R, Diaz V, Nelson JF (2005) Housing density does not influence the longevity effect of calorie restriction. J Gerontol 60A:1510–1517 · DOI · Paper page
  31. Inserra F, Romano L, Ercole L, de Cavanagh EM, Ferder L (1995) Cardiovascular changes by long-term inhibition of the renin-angiotensin system in aging. Hypertension 25:437–42 · DOI
  32. Inserra F, Romano LA, de Cavanagh EM, Ercole L, Ferder LF, Gomez RA (1996) Renal interstitial sclerosis in aging: effects of enalapril and nifedipine. J Am Soc Nephrol 7:676–80 · DOI
  33. Jones RHV, Hothersall JS (1993) Increased susceptibility to metal catalysed oxidation of diabetic lens [beta]L crystallin: possible protection by dietary supplementation with acetylsalicylic acid. Exp Eye Res 57:783–790 · DOI
  34. Kim DH, dos Sarbassov D, Ali SM, Latek RR, Guntur KV, Erdjument-Bromage H, Tempst P, Sabatini DM (2003) GbL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell 11:895–904 · DOI
  35. Klebanov S, Harrison DE (2002) Optimizing detection of QTLs retarding aging: choice of statistical model and animal requirements. Mech Ageing Dev 123:131–44 · DOI
  36. Kuno A, Yamada T, Masuda K, Ogawa K, Sogawa M, Nakamura S Kuno A, Yamada T, Masuda K, Ogawa K, Sogawa M, Nakamura S, Nakazawa T, Ohara H, Nomura T, Joh T, Shirai T, Itoh M (2003) Angiotensin-converting enzyme inhibitor attenuates pancreatic inflammation and fibrosis in male Wistar Bonn/Kobori rats. Gastroenterology 124:1010–1019 · DOI
  37. LaMothe B, Baudry A, Desbois P, Lamotte L, Bucchini D, De Meyts P, Joshi RL (1998) Genetic engineering in mice: impact on insulin signaling and actiuon. Biochem J 335:193–204 · DOI
  38. Lembo G, Rockman HA, Hunter JJ, Steinmetz H, Koch WJ, Ma L, Prinz MP, Ross J, Chien KR, Powell-Braxton L (1996) Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency. J Clin Invest 98:2648–2655 · DOI
  39. Lerman I, Harrison BC, Freeman K, Hewett TE, Allen DL, Robbins J, Leinwand LA (2002) Genetic variability in forced and voluntary endurance performance in seven inbred mouse strains. J Appl Physiol 92:2245–2255 · DOI
  40. Lipman R, Galecki A, Burke DT, Miller RA (2004) Genetic loci that influence cause of death in a heterogeneous mouse stock. J Gerontol 59A:977–983 · DOI · Paper page
  41. Lorberg A, Hall MN (2004) TOR: the first 10 years. Curr Top Microbiol Immunol 279:1–18
  42. Manning BD, Cantley LC (2003) Rheb fills a GAP between TSC and TOR. Trends Biochem Sci 28:573–576 · DOI · Paper page
  43. McLin JP, Thompson LM, Steward O (2006) Differential susceptibility to striatal neurodegeneration induced by quinolinic acid and kainate in inbred, outbred and hybrid mouse strains. Eur J Neurosci 24:3134–3140 · DOI
  44. Miller R, Chrisp C, Jackson AU, Burke D (1998) Marker loci associated with lifespan in genetically heterogeneous mice. J Gerontol Med Sci 53A:M257–M263 · DOI
  45. Miller RA, Chrisp C (1999) Lifelong treatment with oral DHEA sulfate does not preserve immune function, prevent disease, or improve survival in genetically heterogeneous mice. J Am Geriatr Soc 47:960–966 · DOI
  46. Miller RA, Chrisp C, Jackson AU, Galecki AT, Burke DT (2002) Coordinated genetic control of neoplastic and nonneoplastic diseases in mice. J Gerontol 57A:B3–B8 · DOI
  47. Miller RA, Harrison DE, Astle CM, Floyd RA, Flurkey K, Hensley KL, Javors MA, Leeuwenburgh C, Nelson JF, Ongini E, Nadon NL, Warner HR, Strong R (2007) An aging interventions testing program: study design and an interim report. Aging Cell 6:565–575 · DOI · Paper page
  48. Nadon NL (2006) Exploiting the rodent model for studies on the pharmacology of lifespan extension. Aging Cell 5:9–15 · DOI
  49. Nakae D, Kishida H, Enami T, Konishi Y, Hensley KL, Floyd RA, Kotake Y (2003) Effects of phenyl N-tert-butyl nitrone and its derivatives on the early phase of hepatocarcinogenesis in rats fed a choline-deficient, l-amino acid-defined diet. Cancer Sci 94:26–31 · DOI
  50. Ongini E, Bolla M (2006) Nitric-oxide based nonsteroidal anti-inflammatory agents. Drug Discov Today 3:395–400 · DOI
  51. Pugh TD, Oberley TD, Weindruch R (1999) Dietary intervention at middle age: caloric restriction but not dehydroepiandrosterone sulfate increases lifespan and lifetime cancer incidence in mice. Cancer Res 59:1642–1648
  52. Rader JI, Wolnik KA, Gaston CM, Fricke FL, Fox MRS (1986) Purified reference diets for weanling rats: effects of biotin and cellulose. J Nutr 116:1777–1788 · DOI
  53. Sack CA, Socci DJ, Crandall BM, Arendash GW (1996) Antioxidant treatment with phenyl-alpha-tert-butyl nitrone (PBN) improves the cognitive performance and survival of aging rats. Neurosci Lett 205:181–184 · DOI
  54. Saito K, Yoshioka H, Cutler RG (1998) A spin trap, N-tert-butyl-alpha-phenylnitrone extends the life span of mice. Biosci Biotechnol Biochem 62:792–794 · DOI
  55. Shackelford RE, Alford PB, Xue Y, Thai SF, Adams DO, Pizzo S (1997) Aspirin inhibits tumor necrosis factor-alpha gene expression in murine tissue macrophages. Mol Pharmacol 52:421–429 · DOI
  56. Shi X, Min D, Zigang D, Fei C, Jiangping Y, Suwei W, Leonard SS, Vince C, Val V (1999) Antioxidant properties of aspirin: characterization of the ability of aspirin to inhibit silica-induced lipid peroxidation, DNA damage, NF-κB activation, and TNF-α production. Mol Cell Biochem 199:93–102 · DOI
  57. Sud’ina GF, Mirzoeva OK, Pushkareva MA, Korshunova GA, Sumbatyan NV, Varfolomeev SD (1993) Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties. FEBS Lett 329:21–24 · DOI
  58. Talan MI, Ingram DK (1985) Effect of intermittent feeding on thermoregulatory abilities in young and aged C57BL/6J mice. Arch Gerontol Geriatr 4:251–259 · DOI
  59. Tatar M, Bartke A, Antebi A (2003) The endocrine regulation of aging by insulin-like signals. Science 299:1346–1351 · DOI
  60. Turturro A, Witt WW, Lewis S, Hass BS, Lipman RD, Hart RW (1999) Growth curves and survival characteristics of the animals used in the biomarkers of aging program. J Gerontol 54A:B492–B501 · DOI
  61. Valenzano DR, Terzibasi E, Genade T, Cattaneo A, Domenici L, Cellerino A (2006) Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate. Curr Biol 16:296–300 · DOI
  62. Van GT, Kadish I (2005) Transgenic AD model mice, effects of potential anti-AD treatments on inflammation and pathology. Brain Res Brain Res Rev 48:370–378 · DOI
  63. Vane SJ (2000) Aspirin and other anti-inflammatory drugs. Thorax 55:3S–9 · DOI
  64. Volkman SK, Galecki AT, Burke DT, Paczas MR, Moalli MR, Miller RA, Goldstein SA (2003) Quantitative trait loci for femoral size and shape in a genetically heterogeneous mouse population. J Bone Miner Res 18:1497–1505 · DOI
  65. Wang C, Li Q, Redden DT, Weindruch R, Allison DB (2004) Statistical methods for testing effects on “maximum lifespan". Mech Ageing Dev 125:629–632 · DOI · Paper page
  66. Warner HR, Ingram D, Miller RA, Nadon NL, Richardson AG (2000) Meeting Report: Program for testing biological interventions to promote healthy aging. Mech Aging Dev 115:199–208 · DOI
  67. Weber C, Erl W, Pietsch A, Weber PC (1995) Aspirin inhibits nuclear factor kappa B mobilization and monocyte adhesion in stimulated human endothelial cells. Circulation 91:1914–1917 · DOI
  68. Weissmann G (1991) Aspirin. Sci Am 264:84–90 · DOI
  69. West M, Mhatre M, Ceballos A, Floyd RA, Grammas P, Gabbita SP, Hamdheydari L Mai T, Mou S, Pye QN, Stewart C, West S, Williamson KS, Zemlan F, Hensley K (2004) The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice. J Neurochem 91:133–134 · DOI
  70. Wisser KC, Schauerte JA, Burke DT, Galecki A, Chen S, Miller RA, Gafni A (2004) Mapping tissue-specific genes correlated with age-dependent changes in protein stability and function. Arch Biochem Biophys 432:58–70 · DOI
  71. Wolf N, Galecki A, Lipman R, Chen S, Smith-Wheelock M, Burke D, Miller R (2004) Quantitative trait locus mapping for age-related cataract severity and synechia prevalence using four-way cross mice. Invest Ophthalmol Vis Sci 45:1922–1929 · DOI
  72. Zenner L (1999) Pathology, diagnosis and epidemiology of the rodent Helicobacter infection. Comp Immunol Microbiol Infect Dis 22:41–61 · DOI
  73. Zhao Q, Pahlmark K, Smith ML, Siesjo BK (1994) Delayed treatment with the spin trap alpha-phenyl-N-tert-butyl nitrone (PBN) reduces infarct size following transient middle cerebral artery occlusion in rats. Acta Physiol Scand 152:349–350 · DOI
  74. Zraika S, Aston-Mourney K, Laybutt DR, Kebede M, Dunlop ME, Proietto J, Andrikopoulos S (2006) The influence of genetic background on the induction of oxidative stress and impaired insulin secretion in mouse islets. Diabetologia 49:1254–1263 · DOI

Cited by

Sorted by citations

Metadata

Authors
Nadon, N. L., Strong, R., Miller, R. A., Nelson, J., Javors, M., Sharp, Z. D., Peralba, J. M., & Harrison, D. E.
Venue
AGE
Published
2008-04-18
Volume
30
Issue
4
Pages
187-199
ISSN
  • 0161-9152
  • 1574-4647
Cited by
142
References
7
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review