The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Positive effects of resistance training in frail elderly patients with dementia after long-term physical restraint
Open accessAbstract
This study investigated the effects of a multicomponent exercise intervention on muscle strength, incidence of falls and functional outcomes in frail elderly patients with dementia after long-term physical restraint, followed by 24 weeks of training cessation. Eighteen frail elderly patients with mild dementia (88.1 ± 5.1 years) performed a multicomponent exercise program, which consisted of 4 weeks of walking, balance and cognitive exercises, followed by 4 weeks of resistance exercise performed twice weekly [8-12 repetitions at 20-50 % of the one-repetition maximum (1RM)], combined with walking, balance and cognitive exercises. Before and after training, as well as after 24 weeks of training cessation, strength outcomes, Barthel Index, balance, gait ability, rise from a chair ability, dual task performance, incidence of falls and Mini-Mental State Examination were assessed. After the first 4 weeks of training, there was a significant improvement only in the balance test, whereas no additional changes were observed. However, after the second part of the training, the participants required significantly less time for the time-up-and-go test (P < 0.05), and improved the isometric hand grip, hip flexion and knee extension strength, as well as the leg press 1RM (P < 0.01). A significant reduction was also observed in the incidence of falls (P < 0.01). After 24 weeks of training cessation, abrupt decreases were observed in nearly all of the physical outcomes (P < 0.05). The exercise intervention improved strength, balance and gait ability in frail elderly patients with dementia after long-term physical restraint, and these benefits were lost after training cessation.
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“Tailored multicomponent exercise training with a particular emphasis on lower load (30–50% of 1RM) and high-speed PRT may be a cornerstone for enhancing both physical and cognitive functions [109].”
From Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR) (2025) · cites this paper as [109]
In the citing paper
“In a 12-week multicomponent exercise intervention involving institutionalized frail nonagenarians, explosive resistance training improved the muscle cross-sectional area, muscle fat infiltration, maximal strength and power, balance, gait, and sit-to-stand ability, and reduced fall incidence [84,109].”
From Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR) (2025) · cites this paper as [109]
In the citing paper
“The studies provided evidence that both multicomponent exercise and PRT could effectively enhance the physical performance of institutionalized older adults, as measured by the Short Physical Performance Battery, 30-second Chair-Stand, Timed Up and Go tests, and gait ability [84,109,493], and potentially ameliorate frailty and reduce falls [84,109,240].”
From Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR) (2025) · cites this paper as [109]
In the citing paper
“and potentially ameliorate frailty and reduce falls [84,109,240].”
From Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR) (2025) · cites this paper as [109]
In the citing paper
“Research also indicates that PA benefits cognitive functions, mental health [109], and overall well-being [488], supporting its broad utility in improving the quality of life for nursing home residents.”
From Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR) (2025) · cites this paper as [109]
In the citing paper
“Tailored multicomponent exercise training with a particular emphasis on lower load (30–50% of 1RM) and high-speed PRT may be a cornerstone for enhancing both physical and cognitive functions [109].”
From Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR) (2025) · cites this paper as [109]
In the citing paper
“The studies provided evidence that both multicomponent exercise and PRT could effectively enhance the physical performance of institutionalized older adults, as measured by the Short Physical Performance Battery, 30-second Chair-Stand, Timed Up and Go tests, and gait ability [84,109,493], and potentially ameliorate frailty and reduce falls [84,109,240].”
From Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR) (2025) · cites this paper as [109]
In the citing paper
“Research also indicates that PA benefits cognitive functions, mental health [109], and overall well-being [488]”
From Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR) (2025) · cites this paper as [109]
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Cites
Frailty in Older Adults: Evidence for a Phenotype
Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907
The Clinical Dementia Rating (CDR): Current version and scoring rules
Morris, J. C. (1993) · Neurology · doi:10.1212/wnl.43.11.2412-a · Cited by 9,882
Frailty in relation to the accumulation of deficits
Rockwood, K., & Mitnitski, A. (2007) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/62.7.722 · Cited by 3,076
Heyn, P., Abreu, B. C., & Ottenbacher, K. J. (2004) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2004.03.019 · Cited by 1,223
Rodríguez‐Mañas, L., Féart, C., Mann, G. E., Viña, J., Chatterji, S., Chodzko-Zajko, W. J., Harmand, M. G., Bergman, H., Carcaillon‐Bentata, L., Nicholson, C., et al. (2012) · The Journals of Gerontology Series A · doi:10.1093/gerona/gls119 · Cited by 1,187
Frailty: An Emerging Research and Clinical Paradigm--Issues and Controversies
Bergman, H., Ferrucci, L., Guralnik, J., Hogan, D. B., Hummel, S., Karunananthan, S., & Wolfson, C. (2007) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/62.7.731 · Cited by 1,134
“Stops walking when talking” as a predictor of falls in elderly people
Lundin‐Olsson, L., Nyberg, L., & Gustafson, Y. (1997) · The Lancet · doi:10.1016/s0140-6736(97)24009-2 · Cited by 960
Frailty and cognitive impairment—A review of the evidence and causal mechanisms
Robertson, D. A., Savva, G. M., & Kenny, R. A. (2013) · Ageing Research Reviews · doi:10.1016/j.arr.2013.06.004 · Cited by 784
Unstable disability and the fluctuations of frailty
Campbell, A. J., & Büchner, D. M. (1997) · Age and Ageing · doi:10.1093/ageing/26.4.315 · Cited by 602
Boyle, P. A., Buchman, A. S., Wilson, R. S., Leurgans, S. E., & Bennett, D. A. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2009.02671.x · Cited by 510
Exercise comes of age: rationale and recommendations for a geriatric exercise prescription
Singh, M. A. F. (2002) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/57.5.m262 · Cited by 485
Stewart, R., Masaki, K., Xue, Q.-L., Peila, R., Petrovitch, H., White, L. R., & Launer, L. J. (2005) · Archives of Neurology · doi:10.1001/archneur.62.1.55 · Cited by 478
The Dialectics of Dementia: With Particular Reference to Alzheimer's Disease
Kitwood, T. M. (1990) · Ageing and Society · doi:10.1017/s0144686x00008060 · Cited by 432
Frailty is associated with incident Alzheimer's disease and cognitive decline in the elderly
Buchman, A. S., Boyle, P. A., Wilson, R. S., Tang, Y., & Bennett, D. A. (2007) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318068de1d · Cited by 420
Predictors of maintaining cognitive function in older adults: The Health ABC Study
Yaffe, K., Fiocco, A. J., Lindquist, K., Vittinghoff, E., Simonsick, E. M., Newman, A. B., Satterfield, S., Rosano, C., Rubin, S. M., Ayonayon, H. N., et al. (2009) · Neurology · doi:10.1212/wnl.0b013e3181a92c36 · Cited by 396
Montero‐Odasso, M., Muir, S. W., & Speechley, M. R. (2012) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2011.08.026 · Cited by 383
García‐García, F. J., Avila, G. G., Alfaro‐Acha, A., Andrés, M. S. A., Lanza, M. D. L. A. D. L. T., Aparicio, M. V. E., Aparicio, S. H., Zugasti, J. L. L., Reus, M. G.-S., Rodríguez‐Artalejo, F., et al. (2011) · The journal of nutrition health & aging · doi:10.1007/s12603-011-0075-8 · Cited by 308
Bottaro, M., Machado, S. N., Nogueira, W., Scales, R., & Veloso, J. (2007) · European Journal of Applied Physiology · doi:10.1007/s00421-006-0343-1 · Cited by 305
Executive Function, Memory, and Gait Speed Decline in Well-Functioning Older Adults
Watson, N. L., Rosano, C., Boudreau, R. M., Simonsick, E. M., Ferrucci, L., Sutton-Tyrrell, K., Hardy, S. E., Atkinson, H. H., Yaffe, K. S., Satterfield, S., et al. (2010) · The Journals of Gerontology Series A · doi:10.1093/gerona/glq111 · Cited by 289
Walston, J. D., & Fried, L. P. (1999) · Medical Clinics of North America · doi:10.1016/s0025-7125(05)70157-7 · Cited by 262
Why do we use physical restraints in the elderly?
Hamers, J. P. H., & Huizing, A. R. (2005) · Zeitschrift für Gerontologie und Geriatrie · doi:10.1007/s00391-005-0286-x · Cited by 221
Physical Training Improves Motor Performance in People with Dementia: A Randomized Controlled Trial
Hauer, K. A., Schwenk, M., Zieschang, T., Essig, M., Becker, C., & Oster, P. (2011) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2011.03778.x · Cited by 209
Heyn, P. C., Johnsons, K. E., & Kramer, A. F. (2008) · The journal of nutrition health & aging · doi:10.1007/bf02982674 · Cited by 164
Maquet, D., Lekeu, F., Warzee, E., Gillain, S., Wojtasik, V., Salmon, É., Pétermans, J., & Croisier, J. (2009) · Clinical Physiology and Functional Imaging · doi:10.1111/j.1475-097x.2009.00903.x · Cited by 160
Morie, M., Reid, K. F., Miciek, R., Lajevardi, N., Choong, K., Krasnoff, J. B., Storer, T. W., Fielding, R. A., Bhasin, S., & LeBrasseur, N. K. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.03012.x · Cited by 156
Effects of high-speed power training on functional capacity and muscle performance in older women
Pereira, A., Izquierdo, M., Silva, A. J., Costa, A. M., Bastos, E., González-Badillo, J. J., & Marques, M. C. (2012) · Experimental Gerontology · doi:10.1016/j.exger.2011.12.010 · Cited by 146
Self-citationDeaths Due to Physical Restraint
Berzlanovich, A. M., Schöpfer, J., & Keil, W. (2012) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2012.0027 · Cited by 142
Zech, A., Drey, M., Freiberger, E., Hentschke, C., Bauer, J. M., Sieber, C. C., & Pfeifer, K. (2012) · BMC Geriatrics · doi:10.1186/1471-2318-12-68 · Cited by 141
DETRAINING AND TAPERING EFFECTS ON HORMONAL RESPONSES AND STRENGTH PERFORMANCE
Izquierdo, M., Courel‐Ibáñez, J., González‐Badillo, J. J., Ratamess, N. A., Kraemer, W. J., HÄKKINEN, K., Bonnabau, H., Granados, C., French, D. N., & Gorostiaga, E. M. (2007) · The Journal of Strength and Conditioning Research · doi:10.1519/r-21136.1 · Cited by 126
Self-citationHenwood, T. R., & Taaffe, D. R. (2008) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/63.7.751 · Cited by 113
Casas-Herrero, A., Cadore, E. L., Zambom-Ferraresi, F., Idoate, F., Millor, N., Martínez-Ramirez, A., Gómez, M., Rodriguez-Mañas, L., Marcellán, T., de Gordoa, A. R., et al. (2013) · Rejuvenation Research · doi:10.1089/rej.2013.1438 · Cited by 105
Self-citation3 Different Types of Strength Training in Older Women
Correa, C., LaRoche, D., Cadore, E., Reischak-Oliveira, A., Bottaro, M., Kruel, L. F., Tartaruga, M., Radaelli, R., Wilhelm, E., Lacerda, F., et al. (2012) · International Journal of Sports Medicine · doi:10.1055/s-0032-1312648 · Cited by 95
Self-citationEffect of strength training on muscle function in elderly hospitalized patients
Suetta, C., Magnusson, S. P., Beyer, N., & Kjær, M. (2007) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.2007.00712.x · Cited by 88
Thomas, V. S., & Hageman, P. A. (2002) · International Psychogeriatrics · doi:10.1017/s1041610202008244 · Cited by 75
Pereira, A., Izquierdo, M., Silva, A. J., Costa, A. M., González‐Badillo, J. J., & Marques, M. C. (2012) · Experimental Gerontology · doi:10.1016/j.exger.2012.05.014 · Cited by 71
Self-citationFrailty and Quality of Life for People With Alzheimer’s Dementia and Mild Cognitive Impairment
Mhaoláin, A. M. N., Gallagher, D., Crosby, L., Ryan, D., Lacey, L. A., Coen, R. F., Coakley, D., Walsh, J. B., Cunningham, C. J., & LAWLOR, B. A. (2012) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317511435661 · Cited by 54
Physical Restraint: a descriptive study in swiss nursing homes
Hantikainen, V. (1998) · Nursing Ethics · doi:10.1177/096973309800500406 · Cited by 53
Daily muscle activity and quiescence in non-frail, pre-frail, and frail older women
Theou, O., Jones, G. R., Vandervoort, A. A., & Jakobi, J. M. (2010) · Experimental Gerontology · doi:10.1016/j.exger.2010.08.008 · Cited by 49
Zwijsen, S. A., Smalbrugge, M., Zuidema, S. U., Koopmans, R. T. C. M., Bosmans, J. E., van Tulder, M. W., Eefsting, J. A., Gerritsen, D. L., & Pot, A. M. (2011) · BMC Health Services Research · doi:10.1186/1472-6963-11-41 · Cited by 41
Belt restraint reduction in nursing homes: design of a quasi-experimental study
Gulpers, M. J. M., Bleijlevens, M. H. C., van Rossum, E., Capezuti, E., & Hamers, J. P. H. (2010) · BMC Geriatrics · doi:10.1186/1471-2318-10-11 · Cited by 33
Designing studies on the effectiveness of physical training in patients with cognitive impairment
Hauer, K. A., Hüger, D., Zieschang, T., Schwenk, M., Oster, P., Becker, C., & Hauer, K. A. (2008) · Zeitschrift für Gerontologie und Geriatrie · doi:10.1007/s00391-008-0529-8 · Cited by 31
Deterioro cognitivo y riesgo de caída en el anciano
Herrero, Á. C., Martínez‐Velilla, N., & Renedo, F. J. A. (2011) · Revista Española de Geriatría y Gerontología · doi:10.1016/j.regg.2011.05.006 · Cited by 14
Young, F. E. (1982) · Research Management · doi:10.1080/00345334.1982.11756739 · Cited by 11
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Self-citation
Metadata
- Authors
- Cadore, E. L., Moneo, A. B. B., Mensat, M. M., Muñoz, A. R., Casas-Herrero, A., Rodriguez-Mañas, L., & Izquierdo, M.
- Affiliations
- Universidad Pública de Navarra (UPNA) (ES)
- Venue
- AGE
- Published
- 2013-11-16
- Volume
- 36
- Issue
- 2
- Pages
- 801-811
- ISSN
- 0161-9152 (ISSN-L)
- 1574-4647
- PMC
- PMC4039260
- OpenAlex
- W2099800551
- Cited by
- 151
- References
- 43
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 20 · 2023: 19 · 2022: 9 · 2021: 14 · 2020: 14 · 2019: 15 · 2018: 15 · 2017: 15 · 2016: 11 · 2015: 3 · 2014: 5
- FWCI
- 16.46
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- AGE (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- European Commission (278803)
- Topics
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
- Keywords
- resistance training, frail elderly, dementia, physical restraint, multicomponent exercise, muscle strength, balance, gait, falls, detraining, functional outcome, cognitive exercises, walking
- MeSH terms
- Accidental Falls, Aged, Aged, 80 and over, Dementia, Postural Balance, Female, Follow-Up Studies, Gait, Humans, Male, Restraint, Physical, Time Factors, Exercise, Walking, Frail Elderly, Treatment Outcome, Muscle Strength, Resistance Training
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