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MFG-E8 Regulates Microglial Phagocytosis of Apoptotic Neurons

Fuller, Abby D., Van Eldik, Linda J.·2008·Journal of Neuroimmune Pharmacology
DOI 10.1007/s11481-008-9118-2PMC PMC2832904
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Research works printed but not linked: 36

  1. Akakura S, Singh S, Spataro M, Akakura R, Kim JI, Albert ML et al (2004) The opsonin MFG-E8 is a ligand for the alphavbeta5 integrin and triggers DOCK180-dependent Rac1 activation for the phagocytosis of apoptotic cells. Exp Cell Res 292:403–416 doi: 10.1016/j.yexcr.2003.09.011 · DOI
  2. Albert ML, Kim JI, Birge RB (2000) alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells. Nat Cell Biol 2:899–905 doi: 10.1038/35046549 · DOI
  3. Asano K, Miwa M, Miwa K, Hanayama R, Nagase H, Nagata S et al (2004) Masking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice. J Exp Med 200:459–467 doi: 10.1084/jem.20040342 · DOI
  4. Blasi E, Barluzzi R, Bocchini V, Mazzolla R, Bistoni F (1990) Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus. J Neuroimmunol 27:229–237 doi: 10.1016/0165-5728(90)90073-V · DOI
  5. Boddaert J, Kinugawa K, Lambert JC, Boukhtouche F, Zoll J, Merval R et al (2007) Evidence of a role for lactadherin in Alzheimer's disease. Am J Pathol 170:921–929 doi: 10.2353/ajpath.2007.060664 · DOI
  6. Bu HF, Zuo XL, Wang X, Ensslin MA, Koti V, Hsueh W et al (2007) Milk fat globule-EGF factor 8/lactadherin plays a crucial role in maintenance and repair of murine intestinal epithelium. J Clin Invest 117:3673–3683
  7. Chen J, Carey K, Godowski PJ (1997) Identification of Gas6 as a ligand for Mer, a neural cell adhesion molecule related receptor tyrosine kinase implicated in cellular transformation. Oncogene 14:2033–2039 doi: 10.1038/sj.onc.1201039 · DOI
  8. Duan RS, Yang X, Chen ZG, Lu MO, Morris C, Winblad B et al (2008) Decreased fractalkine and increased IP-10 expression in aged brain of APP(swe) transgenic mice. Neurochem Res 33:1085–1089 doi: 10.1007/s11064-007-9554-z · DOI
  9. Erichsen D, Lopez AL, Peng H, Niemann D, Williams C, Bauer M et al (2003) Neuronal injury regulates fractalkine: relevance for HIV-1 associated dementia. J Neuroimmunol 138:144–155 doi: 10.1016/S0165-5728(03)00117-6 · DOI
  10. Fadok VA, Bratton DL, Rose DM, Pearson A, Ezekewitz RA, Henson PM (2000) A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 405:85–90 doi: 10.1038/35011084 · DOI
  11. Fens MH, Mastrobattista E, de Graaff AM, Flesch FM, Ultee A, Rasmussen JT et al (2008) Angiogenic endothelium shows lactadherin-dependent phagocytosis of aged erythrocytes and apoptotic cells. Blood 111:4542–4550 doi: 10.1182/blood-2007-06-094763 · DOI
  12. Garden GA, Moller T (2006) Microglia biology in health and disease. J Neuroimmune Pharmacol 1:127–137 doi: 10.1007/s11481-006-9015-5 · DOI
  13. Hanayama R, Miyasaka K, Nakaya M, Nagata S (2006) MFG-E8-dependent clearance of apoptotic cells, and autoimmunity caused by its failure. Curr Dir Autoimmun 9:162–172
  14. Harrison JK, Jiang Y, Chen S, Xia Y, Maciejewski D, McNamara RK et al (1998) Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia. Proc Natl Acad Sci USA 95:10896–10901 doi: 10.1073/pnas.95.18.10896 · DOI · Paper page
  15. Henson PM, Bratton DL, Fadok VA (2001) The phosphatidylserine receptor: a crucial molecular switch? Nat Rev Mol Cell Biol 2:627–633 doi: 10.1038/35085094 · DOI
  16. Hoffmann PR, deCathelineau AM, Ogden CA, Leverrier Y, Bratton DL, Daleke DL et al (2001) Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells. J Cell Biol 155:649–659 doi: 10.1083/jcb.200108080 · DOI
  17. Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S et al (1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274:99–102 doi: 10.1126/science.274.5284.99 · DOI · Paper page
  18. Ishimoto Y, Ohashi K, Mizuno K, Nakano T (2000) Promotion of the uptake of PS liposomes and apoptotic cells by a product of growth arrest-specific gene, gas6. J Biochem 127:411–417 · DOI
  19. Jinushi M, Nakazaki Y, Dougan M, Carrasco DR, Mihm M, Dranoff G (2007) MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF. J Clin Invest 117:1902–1913 doi: 10.1172/JCI30966 · DOI
  20. Kim TS, Lim HK, Lee JY, Kim DJ, Park S, Lee C et al (2008) Changes in the levels of plasma soluble fractalkine in patients with mild cognitive impairment and Alzheimer's disease. Neurosci Lett 436:196–200 doi: 10.1016/j.neulet.2008.03.019 · DOI
  21. Leonardi-Essmann F, Emig M, Kitamura Y, Spanagel R, Gebicke-Haerter PJ (2005) Fractalkine-upregulated milk-fat globule EGF factor-8 protein in cultured rat microglia. J Neuroimmunol 160:92–101 doi: 10.1016/j.jneuroim.2004.11.012 · DOI
  22. Lindner MD, Hogan JB, Krause RG, Machet F, Bourin C, Hodges DB Jr et al (2006) Soluble Abeta and cognitive function in aged F-344 rats and Tg2576 mice. Behav Brain Res 173:62–75 doi: 10.1016/j.bbr.2006.06.003 · DOI
  23. Miksa M, Wu R, Dong W, Das P, Yang D, Wang P (2006) Dendritic cell-derived exosomes containing milk fat globule epidermal growth factor-factor VIII attenuate proinflammatory responses in sepsis. Shock 25:586–593 doi: 10.1097/01.shk.0000209533.22941.d0 · DOI
  24. Miksa M, Amin D, Wu R, Ravikumar TS, Wang P (2007) Fractalkine-induced MFG-E8 leads to enhanced apoptotic cell clearance by macrophages. Mol Med 13:553–560 doi: 10.2119/2007-00019.Miksa · DOI · Paper page
  25. Miyasaka K, Hanayama R, Tanaka M, Nagata S (2004) Expression of milk fat globule epidermal growth factor 8 in immature dendritic cells for engulfment of apoptotic cells. Eur J Immunol 34:1414–1422 doi: 10.1002/eji.200424930 · DOI
  26. Mochizuki H, Goto K, Mori H, Mizuno Y (1996) Histochemical detection of apoptosis in Parkinson's disease. J Neurol Sci 137:120–123 doi: 10.1016/0022-510X(95)00336-Z · DOI
  27. Petrova TV, Akama KT, Van Eldik LJ (1999) Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2. Proc Natl Acad Sci USA 96:4668–4673 doi: 10.1073/pnas.96.8.4668 · DOI
  28. Savill J, Fadok V (2000) Corpse clearance defines the meaning of cell death. Nature 407:784–788 doi: 10.1038/35037722 · DOI
  29. Stolzing A, Grune T (2004) Neuronal apoptotic bodies: phagocytosis and degradation by primary microglial cells. FASEB J 18:743–745 · DOI
  30. Su JH, Anderson AJ, Cummings BJ, Cotman CW (1994) Immunohistochemical evidence for apoptosis in Alzheimer's disease. Neuroreport 5:2529–2533 · DOI
  31. Thomas LB, Gates DJ, Richfield EK, O'Brien TF, Schweitzer JB, Steindler DA (1995) DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions. Exp Neurol 133:265–272 doi: 10.1006/exnr.1995.1029 · DOI
  32. Todt JC, Hu B, Curtis JL (2004) The receptor tyrosine kinase MerTK activates phospholipase C gamma2 during recognition of apoptotic thymocytes by murine macrophages. J Leukoc Biol 75:705–713 doi: 10.1189/jlb.0903439 · DOI
  33. Witting A, Muller P, Herrmann A, Kettenmann H, Nolte C (2000) Phagocytic clearance of apoptotic neurons by microglia/brain macrophages in vitro. Involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition. J Neurochem 75:1060–1070 doi: 10.1046/j.1471-4159.2000.0751060.x · DOI
  34. Wu Y, Tibrewal N, Birge RB (2006) Phosphatidylserine recognition by phagocytes: a view to a kill. Trends Cell Biol 16:189–197 doi: 10.1016/j.tcb.2006.02.003 · DOI
  35. Yamaguchi H, Takagi J, Miyamae T, Yokota S, Fujimoto T, Nakamura S et al (2008) Milk fat globule EGF factor 8 in the serum of human patients of systemic lupus erythematosus. J Leukoc Biol 83:1300–1307 doi: 10.1189/jlb.1107730 · DOI
  36. Zhang L, Kokkonen G, Roth GS (1995) Identification of neuronal programmed cell death in situ in the striatum of normal adult rat brain and its relationship to neuronal death during aging. Brain Res 677:177–179 doi: 10.1016/0006-8993(95)00197-X · DOI

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Metadata

Authors
Fuller, A. D., & Van Eldik, L. J.
Venue
Journal of Neuroimmune Pharmacology
Publisher
Springer Science and Business Media LLC
Published
2008-08-01
Volume
3
Issue
4
Pages
246-256
ISSN
  • 1557-1890
  • 1557-1904
DOI
10.1007/s11481-008-9118-2
PMC
PMC2832904
Cited by
130
References
9
Language
en

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