Psychological pain, depression, and suicide: Recent evidences and future directions
Abstract
Purpose of review The definition of psychological pain is complex. It is a lasting unpleasant and unsustainable feeling characterized by a perception of inability or deficiency of the self, as well as frustrated psychological needs and social disconnection. The aim of our review was to summarize the most recent and updated findings supporting the role of psychological pain in the pathophysiology of depression and suicidal behavior. We also explored the relationship between psychological and physical pain in depression and suicide.Recent findings Psychological pain is a prominent dimension of depressive disorder and has been associated with higher risk of suicidal ideation and suicidal behavior. Sensitivity to psychological and physical pain is increased in depression. Conversely, higher tolerance to physical pain is associated with suicidal behavior. A better understanding of the pathophysiology of pain processing in depression and suicide offers new therapeutic options for the treatment of depression through the use of analgesic drugs.
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Ketamine's rapid reduction in suicidal ideation might partially derive from its impact on psychological pain.
“Conejero et al. [52] noted that ketamine’s rapid reduction in suicidal ideation might partially derive from its impact on psychological pain.”
From Targeting Psychological Pain After a Suicide Attempt: Scoping Review and Intervention Protocol (2026) · cites this paper as [52]
The reviewed studies show that both psychological pain and suicidal ideation were reduced after intervention.
“The reviewed studies show that both psychological pain and suicidal ideation were reduced after intervention [38,39,40,43,50,52].”
From Targeting Psychological Pain After a Suicide Attempt: Scoping Review and Intervention Protocol (2026) · cites this paper as [52]
Cites
Diagnostic and Statistical Manual of Mental Disorders(DSM)
Leong, F. T. L. (2008) · Sage eBooks · doi:10.4135/9781412963978.n182 · Cited by 10,858 · see citing works
(1993) · Cited by 7,136 · see citing works
Baumeister, R. F. (1990) · Psychological Review · doi:10.1037/0033-295x.97.1.90 · Cited by 1,919 · see citing works
Williams, K. D. (2007) · Annual Review of Psychology · doi:10.1146/annurev.psych.58.110405.085641 · Cited by 1,828 · see citing works
(1979) · PubMed · Cited by 1,355 · see citing works
Chu, C., Buchman-Schmitt, J. M., Stanley, I. H., Hom, M. A., Tucker, R. P., Hagan, C. R., Rogers, M. L., Podlogar, M. C., Chiurliza, B., Ringer, F. B., et al. (2017) · Psychological Bulletin · doi:10.1037/bul0000123 · Cited by 1,231 · see citing works
Murrough, J. W., Iosifescu, D. V., Chang, L. C., Al Jurdi, R. K., Green, C. E., Perez, A. M., Iqbal, S., Pillemer, S., Foulkes, A., Shah, A., et al. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.13030392 · Cited by 1,205 · see citing works
Factor structure, reliability, and validity of the Pain Catastrophizing Scale
Osman, A., Barrios, F. X., Kopper, B. A., Hauptmann, W., Jones, J., & O'Neill, E. (1997) · Journal of Behavioral Medicine · doi:10.1023/a:1025570508954 · Cited by 881 · see citing works
Chang, L. J., Yarkoni, T., Khaw, M. W., & Sanfey, A. G. (2013) · Cerebral Cortex · doi:10.1093/cercor/bhs065 · Cited by 879 · see citing works
Nummenmaa, L., Glerean, E., Hari, R., & Hietanen, J. K. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1321664111 · Cited by 871 · see citing works
Joiner, T. E., Van Orden, K. A., Witte, T. K., Selby, E. A., Ribeiro, J. D., Lewis, R., & Rudd, M. D. (2009) · Journal of Abnormal Psychology · doi:10.1037/a0016500 · Cited by 814 · see citing works
Commentary: Suicide as Psychache
SHNEIDMAN, E. S. (1993) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199303000-00001 · Cited by 775 · see citing works
Social rejection shares somatosensory representations with physical pain
Kross, E., Berman, M. G., Mischel, W., Smith, E. E., & Wager, T. D. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1102693108 · Cited by 689 · see citing works
Emotional information processing in mood disorders: a review of behavioral and neuroimaging findings
Leppänen, J. M. (2006) · Current Opinion in Psychiatry · doi:10.1097/01.yco.0000191500.46411.00 · Cited by 632 · see citing works
Are there two qualitatively distinct forms of dissociation? A review and some clinical implications
Holmes, E. A., Brown, R. J., Mansell, W., Fearon, R. P., Hunter, E. C. M., Frasquilho, F., & Oakley, D. A. (2005) · Clinical Psychology Review · doi:10.1016/j.cpr.2004.08.006 · Cited by 619 · see citing works
Klein, D. F. (1974) · Archives of General Psychiatry · doi:10.1001/archpsyc.1974.01760160005001 · Cited by 601 · see citing works
The neural bases of social pain: Evidence for shared representations with physical pain
Eisenberger, N. I. (2012) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3182464dd1 · Cited by 492 · see citing works
Comorbid Chronic Pain and Depression: Who Is at Risk?
Miller-Matero, L. R., & Caño, A. (2009) · Journal of Pain · doi:10.1016/j.jpain.2008.12.007 · Cited by 323 · see citing works
Impulsivity and suicidality: The mediating role of painful and provocative experiences
Bender, T. W., Gordon, K. H., Bresin, K., & Joiner, T. E. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.07.023 · Cited by 317 · see citing works
Yovell, Y., Bar, G., Mashiah, M., Baruch, Y., Briskman, I., Asherov, J., Lotan, A., Rigbi, A., & Panksepp, J. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2015.15040535 · Cited by 311 · see citing works
An experimental study of shared sensitivity to physical pain and social rejection
Eisenberger, N. I., Jarcho, J. M., Lieberman, M. D., & Naliboff, B. D. (2006) · Pain · doi:10.1016/j.pain.2006.06.024 · Cited by 304 · see citing works
Mental Pain and Suicide: A Systematic Review of the Literature
Verrocchio, M. C., Carrozzino, D., Marchetti, D., Andreasson, K., Fulcheri, M., & Bech, P. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00108 · Cited by 297 · see citing works
Bohus, M., Limberger, M. F., Ebner, U., Glocker, F. X., Schwarz, B., Wernz, M., & Lieb, K. (2000) · Psychiatry Research · doi:10.1016/s0165-1781(00)00179-7 · Cited by 270 · see citing works
Mental Pain: A Multidimensional Operationalization and Definition
Orbach, I., Mikulincer, M., Sirota, P., & Gilboa‐Schechtman, E. (2003) · Suicide and Life-Threatening Behavior · doi:10.1521/suli.33.3.219.23219 · Cited by 257 · see citing works
Meerwijk, E. L., Ford, J. M., & Weiss, S. J. (2012) · Brain Imaging and Behavior · doi:10.1007/s11682-012-9179-y · Cited by 227 · see citing works
Further Suicidal Behavior Among Medically Serious Suicide Attempters
Beautrais, A. L. (2004) · Suicide and Life-Threatening Behavior · doi:10.1521/suli.34.1.1.27772 · Cited by 226 · see citing works
Response of the μ-opioid system to social rejection and acceptance
Hsu, D. T., Sanford, B. J., Meyers, K. K., Love, T. M., Hazlett, K. E., Wang, H., Ni, L., Walker, S. J., Mickey, B. J., Korycinski, S. T., et al. (2013) · Molecular Psychiatry · doi:10.1038/mp.2013.96 · Cited by 225 · see citing works
The impact of physical pain on suicidal thoughts and behaviors: meta-analyses
Calati, R., Laglaoui Bakhiyi, C., Artero, S., Ilgen, M., & Courtet, P. (2015) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.09.004 · Cited by 216 · see citing works
Self-citationDepression and changed pain perception: Hints for a central disinhibition mechanism
Klauenberg, S., Maier, C., Assion, H., Hoffmann, A., Krumova, E. K., Magerl, W., Scherens, A., Treede, R., & Juckel, G. (2008) · Pain · doi:10.1016/j.pain.2008.09.003 · Cited by 210 · see citing works
Smith, P. N., Cukrowicz, K. C., Poindexter, E. K., Hobson, V., & Cohen, L. M. (2010) · Depression and Anxiety · doi:10.1002/da.20701 · Cited by 202 · see citing works
Smith, M. T., Edwards, R. R., Robinson, R. C., & Dworkin, R. H. (2004) · Pain · doi:10.1016/j.pain.2004.06.016 · Cited by 194 · see citing works
Thompson, T., Correll, C. U., Gallop, K., Vancampfort, D., & Stubbs, B. (2016) · Journal of Pain · doi:10.1016/j.jpain.2016.08.007 · Cited by 194 · see citing works
Clarifying the role of pain tolerance in suicidal capability
Franklin, J. C., Hessel, E. T., & Prinstein, M. J. (2011) · Psychiatry Research · doi:10.1016/j.psychres.2011.08.001 · Cited by 187 · see citing works
Functional connectivity of the human insular cortex during noxious and innocuous thermal stimulation
Peltz, E., Seifert, F., DeCol, R., Dörfler, A., Schwab, S., & Maihöfner, C. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2010.09.012 · Cited by 175 · see citing works
An fMRI study on mental pain and suicidal behavior
Reisch, T., Seifritz, E., Esposito, F., Wiest, R., Valach, L., & Michel, K. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.03.005 · Cited by 173 · see citing works
Ludäscher, P., Bohus, M., Lieb, K., Philipsen, A., Jochims, A., & Schmahl, C. (2007) · Psychiatry Research · doi:10.1016/j.psychres.2005.04.009 · Cited by 163 · see citing works
Insular cortex mediates increased pain tolerance in yoga practitioners
Villemure, C., eko, M., Cotton, V. A., & Bushnell, M. C. (2014) · Cerebral Cortex · doi:10.1093/cercor/bht124 · Cited by 163 · see citing works
Psychological Pain in Suicidality: A Meta-Analysis
Ducasse, D., Holden, R. R., Boyer, L., Artéro, S., Calati, R., Guillaume, S., Courtet, P., & Olié, E. (2018) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.16r10732 · Cited by 162 · see citing works
Self-citationPain perception threshold in major depression
Adler, G., & Gattaz, W. F. (1993) · Biological Psychiatry · doi:10.1016/0006-3223(93)90041-b · Cited by 156 · see citing works
Schier, A. R. D. M., Ribeiro, N. D. C. R., Coutinho, D. C. O., Machado, S. E. D. C., Arias-Carrión, Ó., Crippa, J. A. S., Zuardi, A. W., Nardi, A. E., & Silva, A. R. (2014) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527313666140612114838 · Cited by 154 · see citing works
Thresholds and tolerance of physical pain in suicidal and nonsuicidal adolescents
Orbach, I., Mikulincer, M., King, R., Cohen, D., & Stein, D. (1997) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.65.4.646 · Cited by 154 · see citing works
Thresholds and tolerance of physical pain in suicidal and nonsuicidal adolescents.
Orbach, I., Mikulincer, M., King, R. A., Cohen, D. J., & Stein, D. J. (1997) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.65.4.646 · Cited by 153 · see citing works
The link between dissociation and both suicide attempts and non-suicidal self-injury: Meta-analyses
Calati, R., Bensassi, I., & Courtet, P. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.01.035 · Cited by 138 · see citing works
Self-citationMonteleone, P., Bifulco, M., Maina, G., Tortorella, A. A. V., Gazzerro, P., Proto, M., Filippo, C. D., Monteleone, F., Canestrelli, B., & Buonerba, G. (2010) · Pharmacological Research · doi:10.1016/j.phrs.2010.01.002 · Cited by 137 · see citing works
Tossani, E. (2013) · Psychotherapy and Psychosomatics · doi:10.1159/000343003 · Cited by 137 · see citing works
Endocannabinoid system: Role in depression, reward and pain control (Review)
Huang, W., Chen, W., & Zhang, X. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5585 · Cited by 135 · see citing works
Perception of Social Participation in Borderline Personality Disorder
Renneberg, B., Herm, K., Hahn, A., Staebler, K., Lammers, C., & Roepke, S. (2012) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.772 · Cited by 134 · see citing works
Role of ketamine for analgesia in adults and children
Urman, R., Vadivelu, N., Schermer, E., Kodumudi, V., Belani, K. G., & Kaye, A. (2015) · Journal of Anaesthesiology Clinical Pharmacology · doi:10.4103/0970-9185.168149 · Cited by 128 · see citing works
Assessment of psychological pain in major depressive episodes
Mee, S., Bunney, B. G., Bunney, W. E., Hetrick, W. P., Potkin, S. G., & Reist, C. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.06.011 · Cited by 122 · see citing works
The functional neuroanatomy of mental pain in depression
van Heeringen, K., Van den Abbeele, D., Vervaet, M., Soenen, L., & Audenaert, K. (2010) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2009.07.011 · Cited by 113 · see citing works
O'Connor, R. C., Fraser, L., Whyte, M.-C., MacHale, S., & Masterton, G. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.01.008 · Cited by 111 · see citing works
Anestis, M. D., Pennings, S. M., Lavender, J. M., Tull, M. T., & Gratz, K. L. (2013) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2013.04.005 · Cited by 100 · see citing works
Orbach, I., Stein, D. J., Palgi, Y., Asherov, J., Har‐Even, D., & Elizur, A. (1996) · Journal of Psychiatric Research · doi:10.1016/0022-3956(96)00008-8 · Cited by 94 · see citing works
PAIN AND DEPRESSION: THE EGG AND THE CHICKEN STORY REVISITED
Gambassi, G. (2009) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2009.09.018 · Cited by 93 · see citing works
Meerwijk, E. L., Ford, J. M., & Weiss, S. J. (2015) · Biological Psychology · doi:10.1016/j.biopsycho.2015.01.003 · Cited by 84 · see citing works
Grounded Theory Analysis of Emotional Pain
Bolger, E. A. (1999) · Psychotherapy Research · doi:10.1093/ptr/9.3.342 · Cited by 84 · see citing works
Slavich, G. M., Tartter, M. A., Brennan, P. A., & Hammen, C. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2014.07.009 · Cited by 83 · see citing works
Edwards, R. R., Magyar‐Russell, G., Thombs, B. D., Smith, M. T., Holavanahalli, R. K., Patterson, D. R., Blakeney, P., Lezotte, D. C., Haythornthwaite, J. A., & Fauerbach, J. A. (2007) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2007.05.031 · Cited by 79 · see citing works
Tolerance for physical pain in suicidal subjects
Orbach, I., Palgi, Y., Stein, D. J., Har‐Even, D., Lotem‐Peleg, M., Asherov, J., & Elizur, A. (1996) · Death Studies · doi:10.1080/07481189608252786 · Cited by 69 · see citing works
Minocci, D., Massei, J., Martino, A., Milianti, M., Piz, L., Bello, D. D., Sbrana, A., Martinotti, E., Rossi, A. M., & Nieri, P. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.05.023 · Cited by 61 · see citing works
Spectroscopy markers of suicidal risk and mental pain in depressed patients
Jollant, F., Near, J., Turecki, G., & Richard-Devantoy, S. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.10.005 · Cited by 61 · see citing works
Campos, R. C., & Holden, R. R. (2015) · Journal of Clinical Psychology · doi:10.1002/jclp.22196 · Cited by 57 · see citing works
A Neural Basis for the Acquired Capability for Suicide
Deshpande, G., Baxi, M., Witte, T. K., & Robinson, J. L. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00125 · Cited by 53 · see citing works
Toward a Unifying Definition: Response to ‘The Concept of Mental Pain'
Meerwijk, E. L., & Weiss, S. J. (2013) · Psychotherapy and Psychosomatics · doi:10.1159/000348869 · Cited by 52 · see citing works
Pain perception in major depressive disorder: A neurophysiological case–control study
Marsala, S. Z., Pistacchi, M., Tocco, P., Gioulis, M., Fabris, F., Brigo, F., & Tinazzi, M. (2015) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2015.06.051 · Cited by 51 · see citing works
Grounded Theory Analysis of Emotional Pain
Bolger, E. A. (1999) · Psychotherapy Research · doi:10.1080/10503309912331332801 · Cited by 44 · see citing works
Physical and Social Pains in Borderline Disorder and Neuroanatomical Correlates: A Systematic Review
Ducasse, D., Courtet, P., & Olié, É. (2014) · Current Psychiatry Reports · doi:10.1007/s11920-014-0443-2 · Cited by 40 · see citing works
Self-citationFertuck, E. A., Karan, E., & Stanley, B. (2016) · Borderline Personality Disorder and Emotion Dysregulation · doi:10.1186/s40479-016-0036-2 · Cited by 40 · see citing works
Differential processing of physical and psychological pain during acute suicidality
Cáceda, R., Kordsmeier, N. C., Golden, E., Gibbs, H. M., & Delgado, P. L. (2017) · Psychotherapy and Psychosomatics · doi:10.1159/000450713 · Cited by 39 · see citing works
Brain mechanisms in manic depression
Carroll, B. J. (1994) · Clinical Chemistry · doi:10.1093/clinchem/40.2.303 · Cited by 33 · see citing works
Psychology and psychoanalysis*
Sandler, J. (1962) · British Journal of Medical Psychology · doi:10.1111/j.2044-8341.1962.tb00507.x · Cited by 31 · see citing works
History of Suicidal Behaviour and Analgesic Use in Community-Dwelling Elderly
Olié, É., Courtet, P., Poulain, V., Guillaume, S., Ritchie, K. A., & Artéro, S. (2013) · Psychotherapy and Psychosomatics · doi:10.1159/000350504 · Cited by 31 · see citing works
Self-citationLevi‐Belz, Y., Gvion, Y., Grisaru, S., & Apter, A. (2017) · Archives of Suicide Research · doi:10.1080/13811118.2017.1355288 · Cited by 28 · see citing works
Meerwijk, E. L., Chesla, C. A., & Weiss, S. J. (2014) · Psychophysiology · doi:10.1111/psyp.12175 · Cited by 25 · see citing works
Jacob, L., Haro, J. M., & Koyanagi, A. (2017) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2017.12.007 · Cited by 23 · see citing works
Psychache, Depression, and Personality
Lester, D. (2000) · Psychological Reports · doi:10.2466/pr0.2000.87.3.940 · Cited by 22 · see citing works
Can the functional MRI responses to physical pain really tell us why social rejection “hurts”?
Iannetti, G. D., & Mouraux, A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1105451108 · Cited by 19 · see citing works
Headache Disability, Suicidality and Pain Catastrophization - Are They Related
Rathod, H. (2016) · JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH · doi:10.7860/jcdr/2016/22636.8772 · Cited by 18 · see citing works
Calati, R., Olié, É., Ritchie, K. A., Artéro, S., & Courtet, P. (2017) · Psychotherapy and Psychosomatics · doi:10.1159/000478021 · Cited by 18 · see citing works
Self-citationCampos, R. C., Holden, R. R., & Santos, S. (2017) · Journal of Clinical Psychology · doi:10.1002/jclp.22518 · Cited by 13 · see citing works
956 – History Of Suicidal Behavior And Analgesic Use In Community-dwelling Elderly
Olié, É., Courtet, P., Poulain, V., et al. (2013) · European Psychiatry · doi:10.1016/s0924-9338(13)76102-9 · Cited by 5 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Unveiling the interoception impairment in various major depressive disorder stages
Zhou, H., Liu, J., Wu, Y., Huang, Z., Wang, W., Ma, Y., Zhu, H., Zhou, Z., Wang, J., & Jiang, C. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14923 · Cited by 13 · see citing works
Lengvenyte, A., Strumila, R., Courtet, P., Kim, S. Y. H., & Olié, E. (2020) · The Canadian Journal of Psychiatry · doi:10.1177/0706743720931237 · Cited by 13 · see citing works
Self-citationChen, S.-Y., Bian, C., Cheng, Y., Zhao, W.-W., Yan, S.-R., & Zhang, Y.-H. (2023) · BMC Nursing · doi:10.1186/s12912-023-01252-6 · Cited by 6 · see citing works
Let’s Move Towards Precision Suicidology
Courtet, P., & Saiz, P. A. (2025) · Current Psychiatry Reports · doi:10.1007/s11920-025-01605-9 · Cited by 7 · see citing works
Self-citationTargeting Psychological Pain After a Suicide Attempt: Scoping Review and Intervention Protocol
Comendador, L., Palao, D. J., Sanz, A., Andreo-Jover, J., Baca-García, E., Barrigón, M. L., Bobes-Bascarán, M. T., Botí, M. Á., Diaz-Marsá, M., Elices, M., et al. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15083124 · Cited by 2 · see citing works
“Conejero et al. [52] noted that ketamine’s rapid reduction in suicidal ideation might partially derive from its impact on psychological pain.”
- Authors
- Conejero, I., Olié, E., Calati, R., Ducasse, D., & Courtet, P.
- Affiliations
- Université de Montpellier (FR)
- Corresponding author
- Courtet, Philippe
- Venue
- Current Psychiatry Reports
- Published
- 2018-04-05
- Volume
- 20
- Issue
- 5
- Pages
- 33-33
- ISSN
- 1523-3812 (ISSN-L)
- 1535-1645
- OpenAlex
- W2795647682
- Semantic Scholar
- 3bdf307433fc0ec407c15af6b43df3fa9703ee6d
- Cited by
- 206
- References
- 81
- Citations by year
- 2026: 19 · 2025: 41 · 2024: 40 · 2023: 42 · 2022: 27 · 2021: 18 · 2020: 12 · 2019: 5 · 2018: 1
- FWCI
- 1.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Current Psychiatry Reports (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- BOA (University of Milano-Bicocca) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- psychological suffering, depression, suicide, suicidal ideation, pain processing, pain tolerance, pain sensitivity, analgesics, social disconnection, depression pathophysiology
- MeSH terms
- Depression, Depressive Disorder, Humans, Pain, Stress, Psychological, Suicide, Suicide, Attempted, Suicidal Ideation
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