Cited by 130Child Abuse and TraumaStress Responses and CortisolIntimate Partner and Family Violence

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Childhood Abuse and Inflammatory Responses to Daily Stressors

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Gouin, Jean-Philippe, Glaser, Ronald, Malarkey, William B., Beversdorf, David, Kiecolt-Glaser, Janice K.·2012·Annals of Behavioral Medicine

DOI 10.1007/s12160-012-9386-1PMC PMC3699690

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Abstract

BACKGROUND: Childhood abuse leads to greater morbidity and mortality in adulthood. Dysregulated physiological stress responses may underlie the greater health risk among abused individuals. PURPOSE: This study evaluated the impact of childhood abuse on inflammatory responses to naturalistically occurring daily stressors. METHODS: In this cross-sectional study of 130 older adults, recent daily stressors and childhood abuse history were evaluated using the Daily Inventory of Stressful Events and the Childhood Trauma Questionnaire. Blood samples provided data on circulating interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and C-reactive protein (CRP). RESULTS: Childhood abuse history moderated IL-6 levels but not TNF-α and CRP responses to daily stressors. Individuals with a childhood abuse history who experienced multiple stressors in the past 24 h had IL-6 levels 2.35 times greater than those of participants who reported multiple daily stressors but no early abuse history. CONCLUSION: Childhood abuse substantially enhances IL-6 responses to daily stressors in adulthood.

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Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267
The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research
Buysse, D. J., Reynolds, C. F., Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90047-4 · Cited by 35,234
An inventory for measuring clinical anxiety: Psychometric properties.
Beck, A. T., Epstein, N., Brown, G., & Steer, R. A. (1988) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.56.6.893 · Cited by 14,407
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Stewart, A. L., Mills, K. M., King, A. C., Haskell, W. L., Gillis, D., & Ritter, P. L. (2001) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200107000-00010 · Cited by 1,274
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Danese, A., Pariante, C. M., Caspi, A., Taylor, A., & Poulton, R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610362104 · Cited by 1,264
The Development, Validity, and Reliability of the Oars Multidimensional Functional Assessment Questionnaire
Fillenbaum, G. G., & Smyer, M. A. (1981) · Journal of Gerontology · doi:10.1093/geronj/36.4.428 · Cited by 1,127

Show all 28 references

Research works printed but not linked: 1

Bernstein DP, Fink L. Childhood trauma questionnaire: A retrospective self-report. San Antonio: The Psychological Corporation; 1998.

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Pasteuning, J., Broeder, C., Broeders, T. A. A., Busby, R. M., Gathier, A. W., Kuzminskaite, E., Linsen, F., Souama, C., Verhoeven, J. E., Sep, M. S. C., et al. (2025) · Neurobiology of Stress · doi:10.1016/j.ynstr.2025.100737 · Cited by 20
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Authors: Gouin, J.-P., Glaser, R., Malarkey, W. B., Beversdorf, D., & Kiecolt-Glaser, J. K.
Affiliations: Concordia University (CA)
The Ohio State University (US)
University of Missouri (US)
Corresponding author: Gouin, Jean-Philippe
ORCID: Gouin, Jean-Philippe
Malarkey, William B.
Beversdorf, David
Venue: Annals of Behavioral Medicine
Publisher: Oxford University Press (OUP)
Published: 2012-06-20
Volume: 44
Issue: 2
Pages: 287-292
ISSN: 0742-5554 (ISSN-L)
0883-6612
1532-4796
DOI: 10.1007/s12160-012-9386-1
PMC: PMC3699690
OpenAlex: W2077730504
Cited by: 130
References: 28
Citations by year: 2026: 1 · 2025: 6 · 2024: 3 · 2023: 11 · 2022: 11 · 2021: 10 · 2020: 19 · 2019: 8 · 2018: 12 · 2017: 11 · 2016: 8 · 2015: 13 · 2014: 9 · 2013: 6 · 2012: 2
FWCI: 10.88
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Annals of Behavioral Medicine (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: Ohio State University (CA16058, UL1RR025755)
National Institutes of Health (CA‐16058)
National Institute on Aging (AG025732, R21AG025732)
National Cancer Institute (CA16058, P30CA016058)
National Center for Research Resources (UL1RR025755)
Topics: Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Social Sciences › Health › Intimate Partner and Family Violence
Keywords: childhood abuse, childhood trauma, daily hassles, inflammation, interleukin-6, TNF-α, C-reactive protein, physiological stress response, older adults
MeSH terms: Aged, Aged, 80 and over, C-Reactive Protein, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Surveys and Questionnaires, Stress, Psychological, Tumor Necrosis Factor-alpha, Interleukin-6, Adult Survivors of Child Abuse

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Childhood Abuse and Inflammatory Responses to Daily Stressors

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