Cited by 20Probiotics and Fermented FoodsMycotoxins in Agriculture and FoodToxin Mechanisms and Immunotoxins

Evaluation of the Role of Probiotics As a New Strategy to Eliminate Microbial Toxins: A Review

Ghadaksaz, Abdolamir, Nodoushan, Somayeh Mousavi, Sedighian, Hamid, Behzadi, Elham, Fooladi, Abbas Ali Imani·2022·Probiotics and Antimicrobial Proteins

Abstract

Probiotics are living microorganisms that have favorable effects on human and animal health. The most usual types of microorganisms recruited as probiotics are lactic acid bacteria (LAB) and bifidobacteria. To date, numerous utilizations of probiotics have been reported. In this paper, it is suggested that probiotic bacteria can be recruited to remove and degrade different types of toxins such as mycotoxins and algal toxins that damage host tissues and the immune system causing local and systemic infections. These microorganisms can remove toxins by disrupting, changing the permeability of the plasma membrane, producing metabolites, inhibiting the protein translation, hindering the binding to GTP binding proteins to GM1 receptors, or by preventing the interaction between toxins and adhesions. Here, we intend to review the mechanisms that probiotic bacteria use to eliminate and degrade microbial toxins.

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Crossref · 10.1007/s12602-021-09893-2

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Authors
Ghadaksaz, A., Nodoushan, S. M., Sedighian, H., Behzadi, E., & Fooladi, A. A. I.
Affiliations
  • Islamic Azad University, Tehran (IR)
  • Baqiyatallah University of Medical Sciences (IR)
Corresponding author
Fooladi, Abbas Ali Imani
Venue
Probiotics and Antimicrobial Proteins
Published
2022-01-14
Volume
14
Issue
2
Pages
224-237
ISSN
  • 1867-1306 (ISSN-L)
  • 1867-1314
OpenAlex
W4206177584
Cited by
20
References
109
Citations by year
2026: 7 · 2025: 4 · 2024: 1 · 2023: 2 · 2022: 6
FWCI
0.30
Type
journal article
Language
en
Open access
closed
Locations
  • Probiotics and Antimicrobial Proteins (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Mycotoxins in Agriculture and Food
  • Life Sciences › Immunology and Microbiology › Immunology › Toxin Mechanisms and Immunotoxins
Keywords
probiotics, toxin removal, mycotoxins, algal toxins, lactic acid bacteria, Bifidobacterium, plasma membrane permeability, toxin binding inhibition, immune system damage
MeSH terms
Animals, Bacteria, Bifidobacterium, Immune System, Mycotoxins, Probiotics

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