Evaluation of the Role of Probiotics As a New Strategy to Eliminate Microbial Toxins: A Review
Abstract
Probiotics are living microorganisms that have favorable effects on human and animal health. The most usual types of microorganisms recruited as probiotics are lactic acid bacteria (LAB) and bifidobacteria. To date, numerous utilizations of probiotics have been reported. In this paper, it is suggested that probiotic bacteria can be recruited to remove and degrade different types of toxins such as mycotoxins and algal toxins that damage host tissues and the immune system causing local and systemic infections. These microorganisms can remove toxins by disrupting, changing the permeability of the plasma membrane, producing metabolites, inhibiting the protein translation, hindering the binding to GTP binding proteins to GM1 receptors, or by preventing the interaction between toxins and adhesions. Here, we intend to review the mechanisms that probiotic bacteria use to eliminate and degrade microbial toxins.
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The ability of lactic acid bacteria to remove mycotoxins has been studied by other authors, including the mycotoxins analyzed in this work, Aflatoxin B1 and Ochratoxin.
“In addition, the ability of lactic acid bacteria to remove mycotoxins has been studied by other authors [58,59], including the mycotoxins analyzed in our work Aflatoxin B1 [60] and Ochratoxin [61].”
From Probiotic and Antifungal Attributes of Lactic Acid Bacteria Isolates from Naturally Fermented Brazilian Table Olives (2022) · cites this paper as [58]
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Effect of digestion and thermal processing on the stability of microbial cell-aflatoxin B1 complex
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Is Aflatoxin B1 A Biomarker for Pathogenic Potential of Aspergillus flavus?
Qureshi, H. (2014) · Journal of Cell Science & Therapy · doi:10.4172/2157-7013.1000188 · Cited by 7 · see citing works
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Simões, L., Fernandes, N., de Souza, A., dos Santos, L., Magnani, M., Abrunhosa, L., Teixeira, J., Schwan, R. F., & Dias, D. R. (2022) · Fermentation · doi:10.3390/fermentation8060277 · Cited by 23 · see citing works
- Authors
- Ghadaksaz, A., Nodoushan, S. M., Sedighian, H., Behzadi, E., & Fooladi, A. A. I.
- Affiliations
- Islamic Azad University, Tehran (IR)
- Baqiyatallah University of Medical Sciences (IR)
- Corresponding author
- Fooladi, Abbas Ali Imani
- Venue
- Probiotics and Antimicrobial Proteins
- Published
- 2022-01-14
- Volume
- 14
- Issue
- 2
- Pages
- 224-237
- ISSN
- 1867-1306 (ISSN-L)
- 1867-1314
- OpenAlex
- W4206177584
- Cited by
- 20
- References
- 109
- Citations by year
- 2026: 7 · 2025: 4 · 2024: 1 · 2023: 2 · 2022: 6
- FWCI
- 0.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Probiotics and Antimicrobial Proteins (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Mycotoxins in Agriculture and Food
- Life Sciences › Immunology and Microbiology › Immunology › Toxin Mechanisms and Immunotoxins
- Keywords
- probiotics, toxin removal, mycotoxins, algal toxins, lactic acid bacteria, Bifidobacterium, plasma membrane permeability, toxin binding inhibition, immune system damage
- MeSH terms
- Animals, Bacteria, Bifidobacterium, Immune System, Mycotoxins, Probiotics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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