Cited by 239Diet and metabolism studiesDietary Effects on HealthDiabetes Management and Research

The DOI matches its Crossref record; 77 of the 78 references it cites were found in a registry or an index.

Nutritional Ketosis for Weight Management and Reversal of Metabolic Syndrome

Open access

Gershuni, Victoria M., Yan, Stephanie L., Medici, Valentina·2018·Current Nutrition Reports

DOI 10.1007/s13668-018-0235-0PMC PMC6472268

Open this paper in CoChat — free account

Abstract

Purpose of review The goal of this paper is to review current literature on nutritional ketosis within the context of weight management and metabolic syndrome, namely, insulin resistance, lipid profile, cardiovascular disease risk, and development of non-alcoholic fatty liver disease. We provide background on the mechanism of ketogenesis and describe nutritional ketosis.Recent findings Nutritional ketosis has been found to improve metabolic and inflammatory markers, including lipids, HbA1c, high-sensitivity CRP, fasting insulin and glucose levels, and aid in weight management. We discuss these findings and elaborate on potential mechanisms of ketones for promoting weight loss, decreasing hunger, and increasing satiety. Humans have evolved with the capacity for metabolic flexibility and the ability to use ketones for fuel. During states of low dietary carbohydrate intake, insulin levels remain low and ketogenesis takes place. These conditions promote breakdown of excess fat stores, sparing of lean muscle, and improvement in insulin sensitivity.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1007/s13668-018-0235-0

Cites

77 of 77 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

1 retracted

A comprehensive review on metabolic syndrome
Kaur, J. (2014) · Cardiology Research and Practice · doi:10.1155/2014/943162 · Cited by 1,889
Retracted
The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
Randle, P. J., Garland, P. B., Hales, C. N., & Newsholme, E. A. (1963) · The Lancet · doi:10.1016/s0140-6736(63)91500-9 · Cited by 5,093
The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
Chalasani, N., Younossi, Z. M., Lavine, J. E., Diehl, A. M., Brunt, E. M., Cusi, K. J., Charlton, M., & Sanyal, A. J. (2012) · Hepatology · doi:10.1002/hep.25762 · Cited by 3,854
Metabolic Syndrome as a Precursor of Cardiovascular Disease and Type 2 Diabetes Mellitus
Wilson, P. W. F., D’Agostino, R. B., Parise, H., SULLIVAN, L. M., & Meigs, J. B. (2005) · Circulation · doi:10.1161/circulationaha.105.539528 · Cited by 2,050
Comparison of Weight-Loss Diets with Different Compositions of Fat, Protein, and Carbohydrates
Sacks, F. M., Bray, G. A., Carey, V. J., Smith, S. R., Ryan, D. H., Anton, S. D., McManus, K., Champagne, C. M., Bishop, L. M., Laranjo, N., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0804748 · Cited by 1,966
Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies
Hokanson, J. E., & Austin, M. A. (1996) · Journal of Cardiovascular Risk · doi:10.1097/00043798-199604000-00014 · Cited by 1,706
Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies
de Souza, R. J., Mente, A., Maroleanu, A., Cozma, A. I., Ha, V., Kishibe, T., Uleryk, E., Budylowski, P., Schünemann, H., Beyene, J., et al. (2015) · BMJ · doi:10.1136/bmj.h3978 · Cited by 1,424
Retinol-Binding Protein 4 and Insulin Resistance in Lean, Obese, and Diabetic Subjects
Graham, T. E., Yang, Q., Blüher, M., Hammarstedt, A., Ciaraldi, T. P., Henry, R. R., Wason, C. J., Oberbach, A., Jansson, P.-A., Smith, U., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa054862 · Cited by 1,319
A Low-Carbohydrate as Compared with a Low-Fat Diet in Severe Obesity
Samaha, F. F., Iqbal, N., Seshadri, P., Chicano, K. L., Daily, D. A., McGrory, J., Williams, T., Williams, M., Gracely, E. J., & Stern, L. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022637 · Cited by 1,267
Dietary carbohydrate restriction as the first approach in diabetes management: critical review and evidence base
Feinman, R. D., Pogozelski, W. K., Astrup, A., Bernstein, R. K., Fine, E. J., Westman, E. C., Accurso, A., Frassetto, L., Gower, B. A., McFarlane, S. I., et al. (2015) · Nutrition · doi:10.1016/j.nut.2014.06.011 · Cited by 912

Show all 78 references

Research works printed but not linked: 1

Obesity and Overweight Fact Sheet. Vol. 2018. World Health Organization; 2017.

Sorted by citations

Items 101–200 of 238

Role of Haptoglobin as a Marker of Muscular Improvement in Patients with Multiple Sclerosis after Administration of Epigallocatechin Gallate and Increase of Beta-Hydroxybutyrate in the Blood: A Pilot Study
Ortí, J. E. D. L. R., Platero, J. L., Benlloch, M., Franco‐Martínez, L., Tvarijonaviciute, A., Escribá-Alepuz, J., & Sancho-Castillo, S. (2021) · Biomolecules · doi:10.3390/biom11050617 · Cited by 12
No Effect of a Ketone Monoester on Markers of Stress and Performance in a Live-Burn Search and Rescue in Firefighters
Waldman, H. S., Bryant, A. R., Shepherd, B. D., Egan, B., & McAllister, M. J. (2022) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000004194 · Cited by 12
Low Carbohydrate Diets for Diabetic Cardiomyopathy: A Hypothesis
Kleissl-Muir, S., Rasmussen, B., Owen, A. J., Zinn, C., & Driscoll, A. L. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.865489 · Cited by 12
Current perspectives in obesity management: unraveling the impact of different therapy approach in real life obesity care
Chokami, K. K., Chokami, A. K., Cammarata, G., Piras, G., Albertelli, M., Gatto, F., Vera, L., Ferone, D., & Boschetti, M. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05322-4 · Cited by 11
Exploring diet-induced ketosis with exogenous ketone supplementation as a potential intervention in post-traumatic stress disorder: a feasibility study
Edwards, M. G. P., Furuholmen-Jenssen, T., Søegaard, E. G. I., Thapa, S. B., & Andersen, J. R. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1406366 · Cited by 11
Therapeutic Potential of Ketogenic Interventions for Autosomal-Dominant Polycystic Kidney Disease: A Systematic Review
Li, D., Dawson, J., & Gunton, J. E. (2024) · Nutrients · doi:10.3390/nu17010145 · Cited by 12
Almond snacking modulates gut microbiome and metabolome in association with improved cardiometabolic and inflammatory markers
Park, G., Johnson, K., Miller, K., Kadyan, S., Singar, S., Patoine, C., Hao, F., Lee, Y., Patterson, A. D., Arjmandi, B. H., et al. (2025) · npj Science of Food · doi:10.1038/s41538-025-00403-0 · Cited by 12
Dietary ketone ester attenuates the accretion of adiposity and liver steatosis in mice fed a high-fat, high-sugar diet
Rushing, K. A., Bolyard, M. L., Kelty, T. J., Wieschhaus, N., Pavela, G., Rector, R. S., & Plaisance, E. P. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1165224 · Cited by 11
The role of ketogenesis in the migratory fattening of the northern wheatear Oenanthe oenanthe
Frias-Soler, R. C., Kelsey, N. A., Pildaín, L. V., Wink, M., & Bairlein, F. (2021) · Biology Letters · doi:10.1098/rsbl.2021.0195 · Cited by 11
Impact of an online multicomponent very-low-carbohydrate program in women with polycystic ovary syndrome: a pilot study
Missel, A. L., O’Brien, A., MASER, H., Kanwal, A., Bayandorian, H., Martin, S., Carrigan, P., McNamee, R., Daubenmier, J. J., Isaman, D. J. M., et al. (2021) · F&S Reports · doi:10.1016/j.xfre.2021.08.008 · Cited by 12
Helichrysum italicum (Roth) G. Don and Helichrysum arenarium (L.) Moench infusions in reversing the traits of metabolic syndrome: a double-blind randomized comparative trial
Kenig, S., Kramberger, K., Novak, K. Š., Karnjuš, I., Bandelj, D., Petelin, A., & Pražnikar, Z. J. (2022) · Food & Function · doi:10.1039/d2fo00880g · Cited by 14
Root Cause for Metabolic Syndrome and Type 2 Diabetes
Baskin, R. G., & Alfakara, D. (2022) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2022.10.007 · Cited by 11
Efficacy and safety of modified medium-chain triglyceride ketogenic diet in patients with drug-resistant epilepsy
Li, H., Wang, Y., Guo, J., Zhang, P., Xu, Z. Q., Peng, K., Dong, X., & Zhao, L. (2024) · Acta Epileptologica · doi:10.1186/s42494-024-00150-x · Cited by 10
Beta-Hydroxybutyrate: A Supplemental Molecule for Various Diseases
Shahtaghi, N. R., Soni, B., Bakrey, H., Bigdelitabar, S., & Jain, S. K. (2024) · Current Drug Targets · doi:10.2174/0113894501312168240821082224 · Cited by 10
Mapping the evolution and impact of ketogenic diet research on diabetes management: a comprehensive bibliometric analysis from 2005 to 2024
Li, Z., Li, A., Liu, P., Zhang, B., & Yan, Y. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1485642 · Cited by 10
Ketogenic diet ameliorates MASLD via balancing mitochondrial dynamics and improving mitochondrial dysfunction
You, Y., Ni, H., Ma, Q., Jiang, L., Cai, J., He, W., Lin, X., Li, K., Wang, Z., Yan, W., et al. (2025) · Nutrition and Diabetes · doi:10.1038/s41387-025-00391-w · Cited by 12
Intermittent fasting reduces mouse body fat while maintaining muscle mass by regulating protein synthesis and autophagy
Yoshii, R., Higashida, K., & Nakai, N. (2023) · Nutrition · doi:10.1016/j.nut.2023.112130 · Cited by 10
Ketosis Suppression and Ageing (KetoSAge) Part 2: The Effect of Suppressing Ketosis on Biomarkers Associated with Ageing, HOMA-IR, Leptin, Osteocalcin, and GLP-1, in Healthy Females
Cooper, I. D., Kyriakidou, Y., Petagine, L., Edwards, K., Soto-Mota, A., Brookler, K. H., & Elliott, B. (2024) · Biomedicines · doi:10.3390/biomedicines12071553 · Cited by 9
Taxifolin as a Therapeutic Potential for Weight Loss: A Retrospective Longitudinal Study
Hattori, Y., Nakaoku, Y., Ogata, S., Saitô, S., Nishimura, K., & Ihara, M. (2025) · Nutrients · doi:10.3390/nu17040706 · Cited by 9
Low-carbohydrate diet enriched with omega-3 and omega-9 fatty acids modulates inflammation and lipid metabolism in the liver and white adipose tissue of a mouse model of obesity
Santamarina, A. B., Moreira, R. G., Mennitti, L. V., Ferreira, Y. A. M., Jucá, A., Prado, C. M., & Pisani, L. P. (2025) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2025.103932 · Cited by 10
The ketogenic diet: a co-therapy in the treatment of mood disorders and obesity - a case report
Pieklik, A., Pawlaczyk, M., Róg, J., & Karakuła‐Juchnowicz, H. (2021) · Current Problems of Psychiatry · doi:10.2478/cpp-2021-0002 · Cited by 9
Impact of a high dietary fiber cereal meal intervention on body weight, adipose distribution, and cardiovascular risk among individuals with type 2 diabetes
Li, X., Shi, Y., Wei, D., Ni, W., Zhu, N., & Yan, X. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1283626 · Cited by 9
Methodological Challenges and Confounders in Research on the Effects of Ketogenic Diets: A Literature Review of Meta-Analyses
Szendi, K., Murányi, E., Hunter, N., & Németh, B. (2024) · Foods · doi:10.3390/foods13020248 · Cited by 12
Six-month effects of modified Atkins diet implementation on indices of cardiovascular disease risk in adults with epilepsy
McDonald, T. J. W., Diaz‐Arias, L. A., Vizthum, D., Henry-Barron, B. J., Schlechter, H., Kossoff, E. H., & Cervenka, M. C. (2021) · Nutritional Neuroscience · doi:10.1080/1028415x.2021.1875301 · Cited by 9
Ketogenic diets in chronic kidney disease patients: a review for skeptics by skeptics
D’Alessandro, C., Giannese, D., Piccoli, G. B., Panichi, V., & Cupisti, A. (2025) · Journal of Nephrology · doi:10.1007/s40620-025-02285-7 · Cited by 8
Glycemic biomarkers in children with drug‐resistant epilepsy on various types of ketogenic diet therapies: A cross‐sectional study
Teng, L., Lee, V. W. M., Murugesu, S., Lee, J., Ibrahim, N. S., Ishak, M. F., Mohamed, A. R., & Khoo, T. (2022) · Epilepsia · doi:10.1111/epi.17292 · Cited by 8
Macronutrient Proportions and Fat Type Impact Ketogenicity and Shape the Circulating Lipidome in Dogs
Jackson, M. I. (2022) · Metabolites · doi:10.3390/metabo12070591 · Cited by 10
The Impact of Time-Restricted Meal Intake on Glycemic Control and Weight Management in Type 2 Diabetes Mellitus Patients: An 18-Month Longitudinal Study
Rastogi, S., Verma, N., Raghuwanshi, G. S., Atam, V., & Verma, D. K. (2024) · Cureus · doi:10.7759/cureus.53680 · Cited by 9
Fasting Ketonuria and the Risk of Incident Nonalcoholic Fatty Liver Disease With and Without Liver Fibrosis in Nondiabetic Adults
Kim, Y., Chang, Y., Kwon, M., Hong, Y. S., Kim, M. K., Sohn, W., Cho, Y. K., Shin, H., Wild, S. H., Byrne, C. D., et al. (2021) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000001344 · Cited by 8
Adaptation to short-term extreme fat consumption alters intestinal lipid handling in male and female mice
Morrow, N. M., Locatelli, C. A. A., Trzaskalski, N. A., Klein, C. T., Hanson, A. A., Al-Hadi, H., Tripathi, I., Clément, A. C., Imran, S., Lorenzen‐Schmidt, I., et al. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2022.159208 · Cited by 8
Are the Modern Diets for the Treatment of Obesity Better than the Classical Ones?
Koliaki, C. C., & Katsilambros, N. L. (2022) · Endocrines · doi:10.3390/endocrines3040052 · Cited by 8
Beyond Weight Loss: Comparative Effects of Tirzepatide Plus Low-Energy Ketogenic Versus Low-Calorie Diet on Hepatic Steatosis and Stiffness in MASLD
Schiavo, L., Santella, B., Mingo, M., Rossetti, G., Orio, M., & Pilone, V. (2025) · Nutrients · doi:10.3390/nu17152409 · Cited by 7
Fasting ketonuria is inversely associated with coronary artery calcification in non-diabetic individuals
Cho, I. Y., Chang, Y., Sung, E., Kim, Y., Kang, J., Shin, H. C., Wild, S. H., Byrne, C. D., & Ryu, S. (2022) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2022.03.018 · Cited by 7
Positive effects of ketogenic diet on weight control in children with obesity due to Prader–Willi syndrome
Kısa, P. T., Güzel, O., Arslan, N., & Demir, K. (2022) · Clinical Endocrinology · doi:10.1111/cen.14864 · Cited by 7
Association between Variation in Body Fat Mass Magnitude and Intake of Nutrients, including Carbohydrates, Fat, and B Vitamins, in a Cohort of Highly Trained Female Athletes
Baranauskas, M., Kupčiūnaitė, I., Lieponienė, J., & Stukas, R. (2023) · Foods · doi:10.3390/foods12224152 · Cited by 7
Adjuvant effect of low-carbohydrate diet on outcomes of patients with recurrent glioblastoma under intranasal perillyl alcohol therapy
dos Santos, J. G., de Faria, G. E., Cruz, W., Fontes, C. A. P., Schönthal, A. H., Quírico‐Santos, T., & da Fonseca, C. O. (2020) · Surgical Neurology International · doi:10.25259/sni_445_2020 · Cited by 7
The Effects of Eating a Traditional High Fat/High Carbohydrate or a Ketogenic Diet on Sensitivity of Female Rats to Morphine
Beltran, N. M., Parra, A. N., Serrano, A. P., Castillo, J. R., Castro, I. M., Elsey, M. K., Minervini, V., & Serafine, K. M. (2024) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.124.002188 · Cited by 6
Metabolic profiles associated with fat loss in Parkinson’s disease
Higashi, A., Mizutani, Y., Ohdake, R., Maeda, Y., Yoshimoto, J., Shima, S., Seino, Y., Ueda, A., Ito, M., Suzuki, A., et al. (2025) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2025-336929 · Cited by 6
Lifestyle Therapy for Obesity
Lambert, D. C., Kane, J., & Newberry, C. A. (2024) · Gastrointestinal Endoscopy Clinics of North America · doi:10.1016/j.giec.2024.03.003 · Cited by 7
Ketogenic diet and β-hydroxybutyrate in osteoporosis: current progress and controversy
Luo, C., Dai, Z., He, W., He, Y., Yang, P. C., Huang, M., Li, J., Xu, Y., & Huang, W. G. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1508695 · Cited by 7
Ketosis in patients undergoing medically supervised therapeutic fasting—results from an observational trial
Thaele-Franz, M.-A., Steckhan, N., Michalsen, A., & Stange, R. (2020) · European Journal of Clinical Nutrition · doi:10.1038/s41430-020-0694-4 · Cited by 7
Dissociation between Corneal and Cardiometabolic Changes in Response to a Time-Restricted Feeding of a High Fat Diet
Akowuah, P. K., Hargrave, A. C., Rumbaut, R. E., & Burns, A. R. (2021) · Nutrients · doi:10.3390/nu14010139 · Cited by 7
Using a Very Low Energy Diet to Achieve Substantial Preconception Weight Loss in Women with Obesity: A Review of the Safety and Efficacy
Price, S., & Sumithran, P. (2022) · Nutrients · doi:10.3390/nu14204423 · Cited by 9
Neuroregeneration Improved by Sodium-D,L-Beta-Hydroxybutyrate in Primary Neuronal Cultures
Ari, C., D’Agostino, D. P., & Cha, B. J. (2024) · Pharmaceuticals · doi:10.3390/ph17091160 · Cited by 6
Effects of intermittent fasting on quality of life tolerance of chemotherapy in patients with gynecological cancers: study protocol of a randomized-controlled multi-center trial
Schmidt, M. W., Brenner, W., Gebhard, S., Schmidt, M., Singer, S., Weidenbach, L., Hahn, H., Puzankova, D., Blau-Schneider, B., Lehnert, A., et al. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1222573 · Cited by 7
Navigating the Spectrum of 4 Evidence-Based Nutrition Options for Type 2 Diabetes Management
Baskin, R. G., & Karp, K. A. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgae646 · Cited by 5
Investigating the role of ketogenic diet and high-dose vitamin C in modulating doxorubicin toxicity in a murine breast cancer model
Al-Jada, D. N., Takruri, H. R., Talib, W. H., Hajeer, M., & Shahin, N. A. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.152311 · Cited by 5
Providing alternative fuel for the brain in anorexia nervosa: a review of the literature on ketones and their effects on metabolism and the brain
Micali, N., Miletta, M. C., Clemmensen, C., Pappaianni, E., Lazeyras, F., Cuenoud, B. M., & Sandi, C. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03591-1 · Cited by 5
Metabolism Meets Epigenetics: β-Hydroxybutyrate–Driven Lysine β-Hydroxybutyrylation Bridging Energy Metabolism With Transcription and Protein Functional Remodeling
Cheng, S., Cheng, C., Zhou, J., Ji, Y. S., Liu, Y., Jiang, W., Liu, C., & Wang, H. (2025) · Nutrition Reviews · doi:10.1093/nutrit/nuaf258 · Cited by 7
Insulin Resistance as a Shared Pathophysiological Driver in Neurological Disorders: a Narrative Review
Atar, A., & Şahin, İ. N. (2026) · Current Nutrition Reports · doi:10.1007/s13668-026-00743-7 · Cited by 5
Role of Macronutrients and Suitability of Upcoming Dietary Trends for Asian Adults with Type 2 Diabetes
Krishnan, D., Manasa, V. S., Gayathri, R., Shobana, S., & Mohan, V. (2021) · Journal of Diabetology · doi:10.4103/jod.jod_50_21 · Cited by 5
Link between emotional and external eating behaviors, peripheral neuropeptide Y, and β-hydroxybutyrate in participants with obesity on 12-week ketogenic diet
Černelič-Bizjak, M., Kenig, S., Petelin, A., Pražnikar, Z. J., & Mohorko, N. (2023) · Nutrition and Health · doi:10.1177/02601060231154464 · Cited by 5
The Impact of the Ketogenic Diet on the Lipid Profile in Adults: A Comprehensive Review and Meta-Regression Analysis of Randomized Controlled Trials
Chang, C., Liu, Y., Rohani, P., Khodadadi, N., Prabahar, K., & Sohouli, M. H. (2026) · Endocrine Practice · doi:10.1016/j.eprac.2026.01.009 · Cited by 4
A retrospective evaluation of an online group ketogenic metabolic therapy intervention on mental health outcomes
Bellamy, E. L. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1751564 · Cited by 4
The Role of Gut Microbiome in Obesity and Weight Management: A Review of Current Evidence and Future Directions
Rehman, A., Ali, N., Tariq, M. R., Ali, S. W., Mushtaq, A., Safdar, W., & Yusuf, A. M. (2026) · Food Science & Nutrition · doi:10.1002/fsn3.71801 · Cited by 5
The glucose ketone index: a proposed quantitative biomarker to support cancer and chronic disease prevention and management
Lee, D. C., Duraj, T., Cooper, I. D., Maroon, J. C., Smith, K., Abdel-Hadi, W., Omene, E., Athanasios, E., & Seyfried, T. N. (2026) · Frontiers in Science · doi:10.3389/fsci.2026.1763395 · Cited by 4
Effects of a two meals-a-day ketogenic diet on newly diagnosed obese patients with type 2 diabetes mellitus: A retrospective observational study
Li, S., Yuan, S., Lin, G., & Zhang, J. (2023) · Medicine · doi:10.1097/md.0000000000035753 · Cited by 5
Effects of 1-Month Very-Low-Calorie Ketogenic Diet on 24-Hour Energy Metabolism and Body Composition in Women With Obesity
Basolo, A., Piaggi, P., Angeli, V., Fierabracci, P., Bologna, C., Vignali, E., Troiani, D., Jaccheri, R., Pelosini, C., Paoli, M., et al. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaf196 · Cited by 5
In silico dietary interventions using whole-body metabolic models reveal sex-specific and differential dietary risk profiles for metabolic syndrome
Alessi, D., McCreery, C. V., & Zomorrodi, A. R. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1586750 · Cited by 5
Dietary Intervention on Overweight and Obesity after Confinement by COVID-19
Ramírez‐Manent, J. I., Tomás-Gil, P., Martí-Lliteras, P., Villalonga, J. L. C., Rifá, E. M.-A., & López‐González, Á. A. (2023) · Nutrients · doi:10.3390/nu15040912 · Cited by 8
Dietary Carbohydrate as Glycemic Load, Not Fat, Coupled with Genetic Permissiveness Favoring Rapid Growth and Extra Calories, Dictate Metabolic Syndrome and Diabetes Induction in Nile Rats (Arvicanthis niloticus)
Subramaniam, A., Park, B.-J., Raphael, D., Landstrom, M., & Hayes, K. C. (2022) · Nutrients · doi:10.3390/nu14153064 · Cited by 4
Low-Carbohydrate (Ketogenic) Diet in Children with Obesity: Part 1—Diet Impact on Anthropometric Indicators and Indicators of Metabolic Syndrome and Insulin Resistance
Paskaleva, I. N., Kaleva, N., Dimcheva, T., Markova, P. P., & Ivanov, I. S. (2025) · Diseases · doi:10.3390/diseases13040094 · Cited by 4
Effects of the ketogenic diet on skin—potential benefits and risks
Chylińska, N., & Maciejczyk, M. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1686056 · Cited by 3
The Ketogenic Diet Effect on Organ Chemistries
Hwaiz, R. A., Mostafa, M., Talaat, S. M., & Merza, M. (2023) · Polytechnic Journal · doi:10.59341/2707-7799.1718 · Cited by 3
The effectiveness of diet intervention in improving the metabolism of overweight and obese women: a systematic review and meta-analysis.
Chen, M., Chen, Q., Liu, W., Tong, H., & Wu, Y. (2022) · PubMed Central · Cited by 3
Can low-carbohydrate diets be recommended for reducing cardiovascular risk?
Berger, A., & Thorn, E. (2022) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000750 · Cited by 4
The effect of the modified Atkins diet and anti-seizure medications on lipid marker levels in adults with epilepsy
Muller, A. L., Diaz‐Arias, L. A., Cervenka, M. C., & McDonald, T. J. W. (2024) · Nutritional Neuroscience · doi:10.1080/1028415x.2024.2397624 · Cited by 3
The challenges associated with a ketogenic diet: a narrative review
Qi, X., & Tester, R. F. (2025) · Exploration of Foods and Foodomics · doi:10.37349/eff.2025.101065 · Cited by 4
Is the very low carbohydrate diet safe for individuals with chronic kidney disease?
Colledge, B. S., Schofield, E. C., Clarke, B. B., Popovic, G. C., Vattekad, M., & Figtree, P. E. (2025) · Journal of Metabolic Health · doi:10.4102/jmh.v8i1.115 · Cited by 3
"Formulating Nutritionally Adequate Low- Carbohydrate Diets: An Analysis of the Australian Food Composition Database"
Turton, J. L. (2022) · Biomedical Journal of Scientific & Technical Research · doi:10.26717/bjstr.2022.44.006991 · Cited by 3
Metabolic dysfunction in youth with major mood disorders: Implications for prevention and early intervention.Preprint
McKenna, S., Carpenter, J., Shin, M., Park, S. H., Crouse, J. J., Scott, E. M., & Hickie, I. B. (2024) · doi:10.33774/coe-2024-xbjwz · Cited by 2
Multi-modal atlas of lifestyle interventions reveals malleability of ageing-linked molecular featuresPreprint
Herzog, C. M. S., Vavourakis, C. D., Redl, E., Hagen, M., Knoll, G., Watschinger, C., Kumar, U., Theeuwes, B., Gasser, J., Zollner-Kiechl, S., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.30.673115 · Cited by 3
The effect of the keto diet on lipid profile with type two diabetic patients
Ghassan, F., Mohammed, A., & Kazim, Z. (2024) · Drug development & registration · doi:10.33380/2305-2066-2024-13-4-1820 · Cited by 2
The effects of initiating a 24-hour fast with a low versus a high carbohydrate shake on glycemic control in older adults: a randomized crossover study
Gipson, E. Z., Deru, L. S., Graves, P. G., Jacobsen, C. G., Peterson, N. E., & Bailey, B. W. (2025) · Nutrition & Metabolism · doi:10.1186/s12986-025-00920-5 · Cited by 3
Exploring the potential of the ketogenic diet in managing metabolic syndrome: mechanisms, strategies, and future research directions
Chen, J., & Yao, J. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1658691 · Cited by 2
Bibliometric analysis of ketogenic diet for pain based on dual databases: global trends and research hotspots from the Web of Science Core Collection and Scopus (2006–2025)
Liao, M., Cheng, X., Liu, F., XIONG, X., & Yu, Y. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1717096 · Cited by 2
Carnivore and Animal-Based Diets in Sport: A Critical Evaluation of Current Evidence and Future Perspectives for Precision Nutrition
Waśkiewicz‬, Z. (2026) · Nutrients · doi:10.3390/nu18060998 · Cited by 2
The Effect of Exogenous Ketones on Signs and Symptoms of Schizophrenia Spectrum and Bipolar Disorders: Study Protocol for a Triple-Blind, Randomized, Controlled Crossover Pilot Study
Dielemans, D. A. M., Yurtkap, Y., van der Pluijm, M., Soeters, M. R., Oranje, B., Smit, D. J. A., Ziermans, T. B., van Tricht, M. J., Muthukumar, S., Prasad, S., et al. (2025) · Current Developments in Nutrition · doi:10.1016/j.cdnut.2025.107480 · Cited by 2
The Prevalence of Ketogenic Diet among Adults with Chronic Disease in Saudi Arabia
Al-Gamdi, K., Alsaud, S. H. A., Alghubaini, G. B., Alsaggaf, M. M., Altalhi, I. A., Asali, J. S., Abyad, S. M., & Alzahrani, K. T. (2021) · International Journal of Innovative Research in Medical Science · doi:10.23958/ijirms/vol06-i01/1061 · Cited by 2
Metabolism
Saghiv, M. S., & Sagiv, M. S. (2020) · Springer eBooks · doi:10.1007/978-3-030-48806-2_2 · Cited by 2
Efek Diet Ketogenik Pada Diabetes Mellitus Tipe 2: Scoping Review
Putri, M. N. H., Dewi, M. A., & Handayani, D. (2022) · Amerta Nutrition · doi:10.20473/amnt.v6i3.2022.326-341 · Cited by 2
Cardiovascular disease and its association with insulin resistance and cholesterol
Ali, N. M., Diamond, D. M., & Rice, S. M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-821617-0.00016-4 · Cited by 2
The ketogenic diet and MetSyn in Parkinson’s disease – Symptoms, biomarkers, depression and anxiety: A case study
Tidman, M. M. (2024) · Journal of Metabolic Health · doi:10.4102/jmh.v7i1.93 · Cited by 2
Following a Low Carbohydrate, High Fat Diet Compared to Reduced Calorie, High Carbohydrate Diet as a Nutritional Intervention in Type Two Diabetes Mellitus Patients: A Systematic Review
Lewis, J., & Haubrick, K. (2020) · Journal of Food Studies · doi:10.5296/jfs.v9i1.17045 · Cited by 3
One size does not fit all
Kloss, K. A., Funnell, M. M., Piatt, G., & Nwankwo, R. B. (2020) · Nursing · doi:10.1097/01.nurse.0000684176.14404.ff · Cited by 2
Systemic multi-omic remodelling underlies health benefits of intermittent fastingPreprint
Herzog, C. M. S., Vavourakis, C. D., Theeuwes, B., Redl, E., Watschinger, C., Knoll, G., Hagen, M., Haider, A., Platzer, H.-P., Kumar, U., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.30.673138 · Cited by 3
A ketogenic diet reduces body weight gain and alters insulin sensitivity and gut microbiota in a mouse model of diet-induced obesity
Heo, S., & Yang, S. J. (2023) · Journal of Nutrition and Health · doi:10.4163/jnh.2023.56.4.349 · Cited by 1
Nutrition and Aging Biology: Summary of a Research Centers Collaborative Network Workshop and Research Needs
Shea, M. K., Lynch, S. D., Brinkley, T. E., & Kritchevsky, S. B. (2025) · Current Developments in Nutrition · doi:10.1016/j.cdnut.2025.107485 · Cited by 2
A randomized controlled trial comparing a very low-calorie low-fat ketogenic diet with a standard hypocaloric diet in adults with class I obesity
Nachón-García, F. J., Saldaña-Dávila, G. E., Valencia, M., & Martinez, C. O. (2025) · Obesity Medicine · doi:10.1016/j.obmed.2025.100642 · Cited by 2
Ketogenic diets: Opportunities and limitations in practical application (LITERATURE REVIEW)
Tyminski, G. (2019) · Archiv Euromedica · doi:10.35630/2199-885x/2019/9/2/22 · Cited by 2
Obesity
Wilcox, C. E. (2021) · Springer eBooks · doi:10.1007/978-3-030-83078-6_2 · Cited by 1
KETOJENİK BESLENME VE SAĞLIK
Ozsoz, C. F., Yıldız, E., & Gürbüz, O. (2022) · Izmir Democracy University Health Sciences Journal · doi:10.52538/iduhes.1093564 · Cited by 6
Novel Secondary Metabolites in Tea and Their Biological Role in Communicable and Noncommunicable Human Diseases
Thirugnanasambantham, K., Nisha, S. N., & Mandal, A. K. A. (2023) · Food bioactive ingredients · doi:10.1007/978-3-031-35221-8_13 · Cited by 1
The effectiveness and health impact of fad diets on obese patients: a literature review
Kraszkiewicz, A., Zaliwska, D., Paduszyńska, N., Dąbrowska, A., Gonciarz, M. J., Czach, M., Strojny, A. A., Adamiec, D. K., Kamińska, M. A., & Do, M. K. (2024) · Quality in Sport · doi:10.12775/qs.2024.16.52872 · Cited by 1
Oral Administration of a Novel, Synthetic Ketogenic Compound Elevates Blood β-Hydroxybutyrate Levels in Mice in Both Fasted and Fed Conditions
Soliven, M. A., Rogers, C. Q., Williams, M. S., Thomas, N. N., Turos, E., & D’Agostino, D. P. (2024) · Nutrients · doi:10.3390/nu16203526 · Cited by 1
Sodium glucose co-transporter 2 inhibitors mediated ketogenesis in patients with metabolic syndrome: clear benefit or anticipated fear?
Patoulias, D. (2019) · Archives of Medical Science - Atherosclerotic Diseases · doi:10.5114/amsad.2019.83302 · Cited by 1
Progress in the Study of Coronary Atherosclerosis and Prevention of Acute Myocardial Infarction
Xu, Q. (2023) · Open Access Journal of Cardiology · doi:10.23880/oajc-16000191 · Cited by 1
Integrating Nutrition, Culinary Medicine, and Agriculture in a Longitudinal, Case-Based Medical Education CurriculumPreprint
Fragomen, F. R., Reigel, C., Dhaliwal, O., Miller, M. G., & Sapola, A. (2023) · Preprints.org · doi:10.20944/preprints202309.0406.v1
A Bibliometric Analysis of Research Hotspots and Frontiers in Diabetes and Cardiovascular Disease Comorbidity from 2005 to 2024Preprint
Wang, J., su, T., Li, Y., Su, Y., & Li, Y. (2024) · medRxiv · doi:10.1101/2024.09.29.24314577 · Cited by 1
Avaliação metabólica e reprodutiva do jejum intermitente em modelo animal de síndrome dos ovários policísticos
Neves, L. P. P. (2019) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.5.2019.tde-13022019-155317

Authors: Gershuni, V. M., Yan, S. L., & Medici, V.
Affiliations: Hospital of the University of Pennsylvania (US)
University of California, Davis (US)
Corresponding author: Gershuni, Victoria M.
ORCID: Gershuni, Victoria M.
Yan, Stephanie L.
Medici, Valentina
Venue: Current Nutrition Reports
Publisher: Springer Science and Business Media LLC
Published: 2018-08-20
Volume: 7
Issue: 3
Pages: 97-106
ISSN: 2161-3311 (ISSN-L)
DOI: 10.1007/s13668-018-0235-0
PMC: PMC6472268
OpenAlex: W2888188466
Cited by: 239
References: 78
Citations by year: 2026: 15 · 2025: 37 · 2024: 40 · 2023: 40 · 2022: 33 · 2021: 34 · 2020: 32 · 2019: 8
FWCI: 2.43
Type: journal article
Language: en
Update notices: correction (2025-03-03)
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.springernature.com/gp/researchers/text-and-data-mining (tdm)
www.springernature.com/gp/researchers/text-and-data-mining (vor)
Locations: Current Nutrition Reports (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
eScholarship (California Digital Library) (submittedVersion)
Funders: National Institutes of Health (TL1TR001880)
National Center for Advancing Translational Sciences
Topics: Health Sciences › Medicine › Physiology (medical) › Diet and metabolism studies
Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Keywords: nutritional ketosis, weight management, weight loss, metabolic syndrome, insulin resistance, ketogenesis, lipid profile, cardiovascular risk, non-alcoholic fatty liver disease, HbA1c, C-reactive protein, satiety, hunger, metabolic flexibility, low-carbohydrate diet, fat oxidation
MeSH terms: Humans, Obesity, Weight Loss, Metabolic Syndrome, Diet, Ketogenic

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Nutritional Ketosis for Weight Management and Reversal of Metabolic Syndrome

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks