Comorbidities of Atopic Dermatitis: Beyond Rhinitis and Asthma
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Purpose of Review: In this review article, we summarize the current evidence about atopic dermatitis (AD)-associated comorbidities, beyond the traditional atopic and allergic conditions. Recent Findings: Patients with AD may have an increased risk of cardiovascular diseases, certain malignancies, autoimmune diseases, and neuropsychiatric diseases. The causes of these associations are likely multifactorial and may include genetic predispositions, systemic low-grade inflammation, environmental exposures, medication, and lifestyle and behavioral risk factors. There appears to be geographical variations in prevalence of comorbidities in patients with AD, indicating that differences in ethnicity and lifestyle factors may significantly influence the risk of certain comorbidities. Summary: The reported comorbidities in recent literature emphasize the burden of disease in patients with AD. Early appropriate AD therapy, in combination with reduction of risk factors, may help prevention of certain comorbidities. The reported observations may generate hypotheses for future investigations in underlying risk factors for AD-associated comorbidities.
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Atopic dermatitis: an expanding therapeutic pipeline for a complex disease
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He, H., Li, R., Choi, S., Zhou, L., Pavel, A. B., Estrada, Y. D., Krueger, J. G., & Guttman‐Yassky, E. (2019) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2019.10.013 · Cited by 87 · see citing works
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Atopic dermatitis is associated with increased prevalence of multiple ocular comorbidities
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Histoire naturelle de la dermatite atopique
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Additional file 1 of Effects of variations in access to care for children with atopic dermatitis
Siegfried, E. C., Paller, A. S., Mina‐Osorio, P., Vekeman, F., Kaur, M., Mallya, U. G., Héroux, J., Miao, R., & Gadkari, A. S. (2020) · Figshare · doi:10.6084/m9.figshare.13467561
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An, Y., Zhou, H., & Ma, L. (2026) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2026.1903179
- Authors
- Andersen, Y. M. F., Egeberg, A., Skov, L., & Thyssen, J. P.
- Affiliations
- University of Copenhagen (DK)
- Corresponding author
- Thyssen, Jacob P.
- Venue
- Current Dermatology Reports
- Published
- 2017-01-21
- Volume
- 6
- Issue
- 1
- Pages
- 35-41
- ISSN
- 2162-4933 (ISSN-L)
- PMC
- PMC5556128
- OpenAlex
- W2578958269
- Cited by
- 62
- References
- 98
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 3 · 2023: 9 · 2022: 6 · 2021: 6 · 2020: 10 · 2019: 11 · 2018: 9 · 2017: 2
- FWCI
- 1.57
- Type
- journal article
- Language
- en
- Update notices
- erratum (2017-08-24)
- Open access
- hybrid
- doi.org
- Locations
- Current Dermatology Reports (publishedVersion, cc-by)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (publishedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
- Keywords
- atopic dermatitis, comorbidities, cardiovascular disease, cancer risk, autoimmune disease, neuropsychiatric disorders, low-grade inflammation, genetic susceptibility, environmental exposure, lifestyle risk factors, regional variation, disease burden
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