Cited by 62Dermatology and Skin DiseasesAsthma and respiratory diseasesContact Dermatitis and Allergies

Comorbidities of Atopic Dermatitis: Beyond Rhinitis and Asthma

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Andersen, Yuki M.F., Egeberg, Alexander, Skov, Lone, Thyssen, Jacob P.·2017·Current Dermatology Reports

Abstract

Purpose of Review: In this review article, we summarize the current evidence about atopic dermatitis (AD)-associated comorbidities, beyond the traditional atopic and allergic conditions. Recent Findings: Patients with AD may have an increased risk of cardiovascular diseases, certain malignancies, autoimmune diseases, and neuropsychiatric diseases. The causes of these associations are likely multifactorial and may include genetic predispositions, systemic low-grade inflammation, environmental exposures, medication, and lifestyle and behavioral risk factors. There appears to be geographical variations in prevalence of comorbidities in patients with AD, indicating that differences in ethnicity and lifestyle factors may significantly influence the risk of certain comorbidities. Summary: The reported comorbidities in recent literature emphasize the burden of disease in patients with AD. Early appropriate AD therapy, in combination with reduction of risk factors, may help prevention of certain comorbidities. The reported observations may generate hypotheses for future investigations in underlying risk factors for AD-associated comorbidities.

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Authors
Andersen, Y. M. F., Egeberg, A., Skov, L., & Thyssen, J. P.
Affiliations
University of Copenhagen (DK)
Corresponding author
Thyssen, Jacob P.
Venue
Current Dermatology Reports
Published
2017-01-21
Volume
6
Issue
1
Pages
35-41
ISSN
2162-4933 (ISSN-L)
OpenAlex
W2578958269
Cited by
62
References
98
Citations by year
2026: 2 · 2025: 4 · 2024: 3 · 2023: 9 · 2022: 6 · 2021: 6 · 2020: 10 · 2019: 11 · 2018: 9 · 2017: 2
FWCI
1.57
Type
journal article
Language
en
Update notices
erratum (2017-08-24)
Open access
Locations
  • Current Dermatology Reports (publishedVersion, cc-by)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (publishedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
  • Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
  • Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
Keywords
atopic dermatitis, comorbidities, cardiovascular disease, cancer risk, autoimmune disease, neuropsychiatric disorders, low-grade inflammation, genetic susceptibility, environmental exposure, lifestyle risk factors, regional variation, disease burden

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