The DOI matches its Crossref record; 130 of the 131 references it cites were found in a registry or an index.
The Anabolic Response to Plant-Based Protein Ingestion
Open accessAbstract
There is a global trend of an increased interest in plant-based diets. This includes an increase in the consumption of plant-based proteins at the expense of animal-based proteins. Plant-derived proteins are now also frequently applied in sports nutrition. So far, we have learned that the ingestion of plant-derived proteins, such as soy and wheat protein, result in lower post-prandial muscle protein synthesis responses when compared with the ingestion of an equivalent amount of animal-based protein. The lesser anabolic properties of plant-based versus animal-derived proteins may be attributed to differences in their protein digestion and amino acid absorption kinetics, as well as to differences in amino acid composition between these protein sources. Most plant-based proteins have a low essential amino acid content and are often deficient in one or more specific amino acids, such as lysine and methionine. However, there are large differences in amino acid composition between various plant-derived proteins or plant-based protein sources. So far, only a few studies have directly compared the muscle protein synthetic response following the ingestion of a plant-derived protein versus a high(er) quality animal-derived protein. The proposed lower anabolic properties of plant- versus animal-derived proteins may be compensated for by (i) consuming a greater amount of the plant-derived protein or plant-based protein source to compensate for the lesser quality; (ii) using specific blends of plant-based proteins to create a more balanced amino acid profile; (iii) fortifying the plant-based protein (source) with the specific free amino acid(s) that is (are) deficient. Clinical studies are warranted to assess the anabolic properties of the various plant-derived proteins and their protein sources in vivo in humans and to identify the factors that may or may not compromise the capacity to stimulate post-prandial muscle protein synthesis rates. Such work is needed to determine whether the transition towards a more plant-based diet is accompanied by a transition towards greater dietary protein intake requirements.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Although the protein found in non–animal-derived sources may be equally digestible, plant sources frequently have lower total EAA contents, and leucine, methionine, and/or lysine in particular, which have been suggested to provide limitations for MPS at either the molecular signaling or substrate availability levels [83].”
From Nutritional Considerations for the Vegan Athlete (2023) · cites this paper as [83]
In the citing paper
“Blending plant-based protein sources is a suggested method to obviate EAA deficiencies [71,83].”
From Nutritional Considerations for the Vegan Athlete (2023) · cites this paper as [83]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
mTOR Signaling in Growth Control and Disease
Laplante, M., & Sabatini, D. M. (2012) · Cell · doi:10.1016/j.cell.2012.03.017 · Cited by 8,509
Protein and amino acid requirements in human nutrition.
(2007) · PubMed · Cited by 2,234
Edible insects: future prospects for food and feed security
van Huis, A., Itterbeeck, J. V., Klunder, H. C., Mertens, E., Halloran, A., Muir, G., & Vantomme, P. (2013) · Socio-Environmental Systems Modeling · Cited by 1,694
Slow and fast dietary proteins differently modulate postprandial protein accretion
Boirie, Y., Dangin, M., Gachon, P., Vasson, M.-P., Maubois, J.-L., & Beaufrère, B. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14930 · Cited by 1,453
WHO technical report series 200 (1960).
Pittman, M. (1974) · PubMed · Cited by 1,447
Sestrin2 is a leucine sensor for the mTORC1 pathway
Wolfson, R. L., Chantranupong, L., Saxton, R. A., Shen, K., Scaria, S. M., Cantor, J. R., & Sabatini, D. M. (2016) · Science · doi:10.1126/science.aab2674 · Cited by 1,306
Morton, R. W., Murphy, K. T., McKellar, S. R., Schoenfeld, B. J., Henselmans, M., Helms, E., Aragon, A. A., Devries, M. C., Banfield, L., Krieger, J. W., et al. (2018) · British Journal of Sports Medicine · doi:10.1136/bjsports-2017-097608 · Cited by 1,269
Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle
Cuthbertson, D., Smith, K., Babraj, J., Leese, G., Waddell, T., Atherton, P., Wackerhage, H., Taylor, P. M., & Rennie, M. J. (2005) · The FASEB Journal · doi:10.1096/fj.04-2640fje · Cited by 1,211
Protein content and amino acid composition of commercially available plant-based protein isolates
Gorissen, S. H. M., Crombag, J. J. R., Senden, J. M. G., Waterval, W. A. H., Bierau, J., Verdijk, L. B., & van Loon, L. J. C. (2018) · Amino Acids · doi:10.1007/s00726-018-2640-5 · Cited by 1,169
Mixed muscle protein synthesis and breakdown after resistance exercise in humans
Phillips, S. M., Tipton, K. D., Aarsland, A., Wolf, S. E., & Wolfe, R. R. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.273.1.e99 · Cited by 1,132
Flagged first, then by citations
1 of the 131 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 101–169 of 169
van Oppenraaij, S. L., Verlaan, S., & Weijs, P. J. M. (2026) · Current Developments in Nutrition · doi:10.1016/j.cdnut.2026.107641 · Cited by 3
Francisco, G. D., Couceiro, C., & Olmedo, R. H. (2026) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-026-04109-z · Cited by 3
Petkova, Y., Johnston, J. D., & Collins, A. L. (2026) · Food Science & Nutrition · doi:10.1002/fsn3.71485 · Cited by 3
Zupančič, Ž., Barnes, T. M., Deutz, M. T., Irwin, G. L., Zimring, J. E., Chen, C., Askow, A. T., ULANOV, A. V., Willard, J. W., van Loon, L. J. C., et al. (2026) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2026.101380 · Cited by 3
Cárcamo-Regla, R., Zapata‐Lamana, R., Ochoa‐Rosales, C., Martorell, M., Carrasco‐Marín, F., & Molina‐Recio, G. (2024) · Nutrients · doi:10.3390/nu16152539 · Cited by 3
Gueugneau, M., Capel, F., Monfoulet, L., & Polakof, S. (2022) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000908 · Cited by 3
Recovery after Exercise-Induced Muscle Damage in Subjects Following a Vegetarian or Mixed Diet
Presti, N., Rideout, T. C., Temple, J. L., Bratta, B., & Hostler, D. P. (2024) · Nutrients · doi:10.3390/nu16162711 · Cited by 2
Kotarsky, C. J., Frenett, M. L., Hoerle, W. F., Kim, J., Lockwood, J., Cryer, L., & Ives, S. J. (2024) · Nutrients · doi:10.3390/nu16203486 · Cited by 2
Safety‐relevant contaminants and nutritional quality of hazelnut skin and pumpkin seed proteins
Mehdizadehtapeh, L., Tekiner, İ. H., Gökşen, G., Ajal, E. A., Yılmazer, Y., Bajoub, A., Bostanci, F., & Ennahli, S. (2025) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.70391 · Cited by 2
Roberts, J., Lillis, J. B., Mercer, J., Mercer, H., Kostopoulos, I., Dopheide, L. H. J., Willmott, A. G. B., Tims, S., Furber, M., van Helvoort, A., et al. (2026) · Current Research in Food Science · doi:10.1016/j.crfs.2026.101359 · Cited by 3
van Kalkeren, C. A. J., Adam, T. C., & Blaak, E. E. (2026) · Advances in Nutrition · doi:10.1016/j.advnut.2026.100610 · Cited by 4
Griffen, C., Renshaw, D. W., Duncan, M., Dallaway, A., Randeva, H. S., Weickert, M. O., & Hattersley, J. G. (2026) · Experimental Gerontology · doi:10.1016/j.exger.2026.113101 · Cited by 2
McClements, D. J. (2023) · Copernicus books · doi:10.1007/978-3-031-23961-8_4 · Cited by 2
van Lieshout, G. A. A., Trommelen, J., Hendriks, F. K., Nyakayiru, J., van Kranenburg, J. M. X., Senden, J. M., Goessens, J. P. B., Verdijk, L. B., Bragt, M. C. E., & van Loon, L. J. C. (2025) · Journal of Nutrition · doi:10.1016/j.tjnut.2025.05.032 · Cited by 2
Meatless Muscle Growth: Building Muscle Size and Strength on a Mycoprotein-Rich Vegan Diet
Hannaian, S. J., & Churchward‐Venne, T. A. (2023) · Journal of Nutrition · doi:10.1016/j.tjnut.2023.04.011 · Cited by 3
Tran, V., Tieland, M., Tan, S., Fyfe, J. J., Feros, S. A., Snipe, R. M. J., Allsopp, G. L., Bruce, C. R., Kowalski, G. M., Mason, S. A., et al. (2025) · Nutrition Journal · doi:10.1186/s12937-025-01226-1 · Cited by 1
Boot, N., Hermans, W. J. H., Warnke, I., Overman, A., van Kranenburg, J. M. X., Senden, J. M., Verdijk, L. B., & van Loon, L. J. C. (2025) · Amino Acids · doi:10.1007/s00726-025-03482-1 · Cited by 1
Valizadeh, S., Mirzapour‐Kouhdasht, A., Lasciers, M., & Tahergorabi, R. (2025) · Food Chemistry X · doi:10.1016/j.fochx.2025.103257 · Cited by 1
Meat in the diet of athletes and active adults
Egan, B. (2025) · Meat Science · doi:10.1016/j.meatsci.2025.110005 · Cited by 1
Influence of Drying Adjuvants on Seriguela (Spondias Purpurea L.) Pulp Powders
Silva, R. D. S., Lima, A. C. D. S., Rodrigues, S., de Aquino, A. C., Neto, J. R. D. V., Silva, L. A. N. D., do Nascimento, R. F., & Afonso, M. R. A. (2025) · Food Biophysics · doi:10.1007/s11483-025-10089-2 · Cited by 1
van Bree, M. A., Kruizenga, H. M., Kühne, R., Schouten, B. C., & Soeters, M. R. (2025) · Clinical Nutrition · doi:10.1016/j.clnu.2025.106553 · Cited by 1
de Stefano, M. I., Monda, A., Maio, G. D., Casillo, M., Messina, A., Monda, V., Moscatelli, F., Monda, M., Polito, R., & Messina, G. (2026) · Sport Sciences for Health · doi:10.1007/s11332-025-01600-w · Cited by 1
Soh, B. X. P., Vignes, M., Smith, N. W., von Hurst, P. R., & McNabb, W. C. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1752697 · Cited by 1
Interactions Between Plant Proteins and Gut Microbiota as Determinants of Intestinal Health
Szydłowska, A., Sionek, B., & Kołożyn‐Krajewska, D. (2026) · Microorganisms · doi:10.3390/microorganisms14030540 · Cited by 5
Rheological and Textural Studies in 3D Printed Meat Analogs From Pea Protein Isolate: A Review
Noh, T. U., & Khalid, N. I. (2026) · Journal of Texture Studies · doi:10.1111/jtxs.70075 · Cited by 1
Wang, S.-N., Liu, Y.-X., Sun, G.-Y., Liu, X., Sun, Y., Ma, Y.-X., Ning, S.-Y., & Shi, Y. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1805807 · Cited by 1
Clemente‐Suárez, V. J., Sancho-Haro, E. S., Yáñez-Sepúlveda, R., Tornero-Aguilera, J. F., & Martín-Rodríguez, A. (2026) · Nutrients · doi:10.3390/nu18142291 · Cited by 1
Domić, J., Grootswagers, P., Pinckaers, P. J., Melchers, M., van Loon, L. J. C., & de Groot, C. P. G. M. (2026) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2026.101416 · Cited by 1
Quaresma, M. V. L. D. S., de Melo, C. M., & Ribeiro, S. M. L. (2022) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2022.07.001 · Cited by 1
Vejetaryen Sporcu Olmak; Besin Tüketimi Nasıl Şekillenmeli?
Zeynep, M. E. T. E., Ersoy, N., & Ersoy, G. (2022) · Sağlık Bilimlerinde Değer · doi:10.33631/sabd.1063256 · Cited by 1
Pratt, J., Acheson, J., Lazaratou, A., Greenhalgh, E. K., Witard, O. C., Sale, C., Hannaian, S. J., Gritsas, A., Churchward‐Venne, T. A., Hearris, M. A., et al. (2025) · The Journal of Nutritional Physiology · doi:10.1016/j.jnphys.2025.100001 · Cited by 1
Insights into Nutritional Properties of Plant Proteins for Health Benefits
Prasad, S., Singh, R., Singh, A., Pandey, A., & Misra, S. (2025) · Springer eBooks · doi:10.1007/978-981-96-4190-1_2 · Cited by 1
Spriet, L. L. (2021) · Sports Medicine · doi:10.1007/s40279-021-01517-7 · Cited by 1
Córdova, L. R. Á., Arteaga-Pazmiño, C. L., Martínez, D. M. S., Quintana, J. V. A., Sánchez-Briones, M., Pérez, D. M. F., & Frías-Toral, E. (2022) · Revista de Nutrición Clínica y Metabolismo · doi:10.35454/rncm.v5n1.366 · Cited by 2
Plant proteins: from processing to digestion
del Rio, A. R. (2022) · doi:10.18174/564000
Sustainable Nutrition and Sport
Vanderstraeten, R. (2022) · Kompass Nutrition & Dietetics · doi:10.1159/000526954
Mendes, A. P., Pereira, F., & Teixeira, V. H. (2023) · Springer eBooks · doi:10.1007/978-3-031-33867-0_5
ANALYSIS OF THE DIET OF FREESTYLE WRESTLERS IN DIFFERENT SEASONS OF THE YEAR
Pastukhova, V. A., Malysheva, T. A., & Buka, G. Y. (2024) · Bulletin of Problems Biology and Medicine · doi:10.29254/2077-4214-2024-4-175-629-639
Presti, N., Rideout, T. C., Temple, J. L., Bratta, B., & Hostler, D. P. (2025) · Nutrients · doi:10.3390/nu17061046
Sukawati, C. I. M. D., & Harimawan, A. I. W. (2025) · Bali Journal of Anesthesiology · doi:10.4103/bjoa.bjoa_71_25
Top 5 Dietary Supplements for Bodybuilders
Haubenstricker, J. E., & Roberts, B. M. (2025) · Strength and conditioning journal · doi:10.1519/ssc.0000000000000925
Fortification of Meat Burger with Protein Isolate Extracted from Local Pumpkin Seeds
Al-Karaquly, I. O. G., & Bayar, A. H. (2025) · Research Journal of Pharmacy and Technology · doi:10.52711/0974-360x.2025.00443
Santini, M. H., Leitão, A. E., Mazzolani, B. C., Smaira, F. I., de Souza, M. A., Santamaria, A., Gualano, B., & Roschel, H. (2025) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2025.2568047 · Cited by 2
Boot, N., Hermans, W. J. H., Kuin, L. M. E., Malowany, J. M., Hendriks, F. K., Warnke, I., Senden, J. M., Overman, A., Goessens, J. P. B., Zorenc, A. H. G., et al. (2025) · Journal of Nutrition · doi:10.1016/j.tjnut.2025.10.018
管, 宇. (2025) · Advances in Clinical Medicine · doi:10.12677/acm.2025.15102906
Guney-Coskun, M., Ersoy, N., & Ersoy, G. (2025) · Research Square · doi:10.21203/rs.3.rs-7534127/v1 · Cited by 1
Ramakrishna, R., Qi, X., & Deng, L. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-91725-4.00013-8
Cárcamo-Regla, R., Alcaide-Leyva, J. M., Zapata-Lamana, R., Martorell, M., Carrasco-Marín, F., & Molina‐Recio, G. (2025) · Nutrition · doi:10.1016/j.nut.2025.113047
Benoit, B., Defois-Fraysse, C., Jalabert, A., Pesenti, S., Brunet, L., Beau, A., Loizon, E., Pinteur, C., Bendridi, N., Nawrot, M., et al. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107175
Sustainability of novel plant proteins in terms of their cost and other functional properties
Tavassoli, M., Madanifar, F., Zarshenas, A., & Hamidi, M. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-32976-0.00012-6
Sustaining Muscle, Cardiovascular Health, and the Environment: Is Plant-Based Protein the Key?
Cannito, T., Ivetac, A., Fiotti, N., Mearelli, F., Bella, S. D., Girolamo, F. G. D., & Biolo, G. (2026) · Nutrients · doi:10.3390/nu18091446 · Cited by 1
Addressing undernutrition in older adults with plant-based products
Horner, K. M., Corish, C. A., & Quinn, A. (2026) · Proceedings of The Nutrition Society · doi:10.1017/s0029665126103000
Comparison of bioelectrical impedance – derived phase angle in vegan and omnivorous exercisers
Sganzerla, G., Hernandes, P. H., Oshiro, B. D. O., Ravagnani, F. C. D. P., Gobbo, L. A., & Coelho‐Ravagnani, C. D. F. (2026) · Brazilian Journal of Kinanthropometry and Human Performance · doi:10.1590/1980-0037.2026v28e109764
Protein Adequacy across Meals in Dutch Elite and Sub-Elite AthletesPreprint
Riccò, A., Grootswagers, P., Mensink, M., & Wardenaar, F. C. (2026) · Research Square · doi:10.21203/rs.3.rs-9640801/v1
Xu, M., Liu, Y., (26302), Z. L., Yang, L., Liu, G., & Xiao, Y. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.6881207
Development of a blueprint for plant-derived hospital meals: a multidisciplinary co-creative study
van Bree, M. A., Kruizenga, H. M., Schouten, B. C., & Soeters, M. R. (2026) · European Journal of Nutrition · doi:10.1007/s00394-026-04040-5
de Vries, J., Singh‐Povel, C. M., Oudhuis, L. A. A. C. M., de Vos, P., & Akkerman, R. (2026) · Nutrients · doi:10.3390/nu18132127
Hossain, M. F., SEZIMOVÁ, K., Mráz, J., Gebauer, R., Zábranský, Ľ., & Roy, K. (2026) · Reviews in Aquaculture · doi:10.1111/raq.70195
Kuin, L. M. E., Hermans, W. J. H., Boot, N., Fuchs, C. J., Senden, J. M., Zorenc, A. H. G., Overman, A., van Kranenburg, J. M. X., Goessens, J. P. B., Verdijk, L. B., et al. (2026) · Journal of Nutrition · doi:10.1016/j.tjnut.2026.101789
Contrasting selective pressures shape human pepsinogen A gene copy-number variation across EurasiaPreprint
Chen, Q., Wang, F., Liu, A., Zhu, Z., Wang, H., Li, X., Wu, D., & Zhang, G. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.08.17.745382
Does protein source influence ageing muscle? A contemporary physiological perspective
Apicella, M. C. A., Korzepa, M., & Breen, L. (2026) · The Journal of Nutritional Physiology · doi:10.1016/j.jnphys.2026.100043
Physiological Adaptation to Plant-Based Diets: A Homeostatic Framework for Sustained Dietary Change
López‐Moreno, M., Nagra, M., Jiménez, M. D. C. F.-F., Gomez-Herrera, G. P., & Kahleová, H. (2026) · Biology · doi:10.3390/biology15171520
UCI Sports Nutrition Project: Position Statement on Nutrition for Cycling
Burke, L. M., Dolan, E., Gonzalez, J. T., Mujika, I., Jeukendrup, A. E., Redegeld, M. I., Martins, G., Valenzuela, P. L., Leo, P. D., Mateo‐March, M., et al. (2026) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2026-0135
van Oppenraaij, S. L., Weijs, P. J. M., & Verlaan, S. (2026) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2026.101533
Xu, M., Liu, Y., Li, Z., Yang, L., Liu, G., & Xiao, Y. (2026) · LWT · doi:10.1016/j.lwt.2026.120033
Riccò, A., Grootswagers, P., Mensink, M., & Wardenaar, F. C. (2026) · Performance Nutrition · doi:10.1186/s44410-026-00031-z
Muñoz‐Pardeza, J., Álvarez-Rodríguez, P., Sepulveda, R. A. Y., Miño, C., Quiroz-Cárdenas, F., Quiroz-Cárdenas, D., Ridgell, L., Yon, D. K., López‐Moreno, M., & López-Gil, J. F. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1961324
Metadata
- Authors
- Pinckaers, P. J. M., Trommelen, J., Snijders, T., & van Loon, L. J. C.
- Affiliations
- Maastricht University Medical Centre (NL)
- Venue
- Sports Medicine
- Published
- 2021-09
- Volume
- 51
- Issue
- S1
- Pages
- 59-74
- ISSN
- 0112-1642 (ISSN-L)
- 1179-2035
- PMC
- PMC8566416
- OpenAlex
- W3200956314
- Cited by
- 170
- References
- 131
- Citations by year
- 2026: 38 · 2025: 44 · 2024: 37 · 2023: 23 · 2022: 22 · 2021: 6
- FWCI
- 2.78
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Sports Medicine (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Research Publications (Maastricht University) (publishedVersion, cc-by)
- VUBIR (Vrije Universiteit Brussel) (submittedVersion)
- Research Publications (Maastricht University) (submittedVersion, cc-by)
- Funders
- Gran Sasso Science Institute
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Life Sciences › Agricultural and Biological Sciences › Food Science › Proteins in Food Systems
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Keywords
- plant proteins, muscle protein synthesis, anabolic response, soy protein, wheat proteins, amino acid composition, essential amino acids, lysine, methionine, protein digestion, sports nutrition, protein requirements, plant-based diet
- MeSH terms
- Amino Acids, Essential, Animals, Dietary Proteins, Eating, Humans, Muscle Proteins, Muscle, Skeletal
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review