Computerized Cognitive Behavioral Therapy for Substance Use Disorders: A Summary of the Evidence and Potential Mechanisms of Behavior Change
Open accessAbstract
Cognitive-behavioral therapy (CBT) is one of the most evaluated behavioral interventions for substance use disorders, with considerable empirical evidence supporting its efficacy. However, despite CBT's strong support from efficacy trials, broad dissemination and implementation have been challenging. Furthermore, there remains limited understanding regarding CBT's mechanisms of behavior change; the theory-driven assumption that individuals acquire new skills for coping with triggers for substance use has notoriously lacked statistical support. The emergence of computer-delivered interventions has the potential to address dissemination and implementation challenges, as well as offer advantages toward understanding treatment mechanisms. This article will provide a summary of the current evidence supporting one particular computerized CBT program, CBT4CBT. Multiple clinical trials in different treatment settings have indicated CBT4CBT's efficacy at reducing rates of alcohol and drug use when provided as an add-on to standard addiction treatment, as well as when provided with minimal clinical monitoring (i.e., virtual stand-alone). These effects have also been relatively durable after treatment termination, consistent with findings of traditional CBT. It is important to note that the evaluation of individuals' cognitive and behavioral coping skills prior and following treatment has indicated the acquisition/improvement of these skills may be a mechanism of behavior change for those who engage with CBT4CBT. Thus, computerized delivery may be a strategy for enhancing individuals' learning of cognitive and behavioral skills for successfully avoiding substance use. Future work should aim to identify the optimal type of setting, clinician role, and patient characteristics for targeted dissemination and implementation.
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Studies found significant reductions in substance use and improved treatment retention with CBT4CBT relative to in-person CBT.
“studies have found significant reductions in substance use and improved retention in treatment using CBT4CBT relative to in-person CBT.81,83”
From The ASAM/AAAP Clinical Practice Guideline on the Management of Stimulant Use Disorder (2024) · cites this paper as [81]
The “Efficacy as a Virtual Stand-Alone Treatment” section reports that CBT4CBT had the best outcomes for retention and substance use in a trial that included therapist-delivered CBT. But it says the trial was not powered for a direct comparison between those treatments; the reported greater reduction in substance use was relative to treatment as usual, not in-person CBT. No page number is supplied in our copy. (LLM, conf=0.89)
Experimental — accuracy not yet measuredCBT4CBT has been shown effective as a standalone treatment in a few studies, but evidence is insufficient to recommend it as standalone.
“CBT4CBT has been shown to be effective as a standalone treatment in a few studies, but this is insufficient evidence to recommend it as a standalone treatment.81,83,92”
From The ASAM/AAAP Clinical Practice Guideline on the Management of Stimulant Use Disorder (2024) · cites this paper as [81]
The ‘Efficacy as a Virtual Stand-Alone Treatment’ section describes two trials in which CBT4CBT was the principal treatment, accompanied by brief weekly clinical monitoring. The Summary and Discussion calls this virtual stand-alone approach efficacious, but the paper does not say the evidence is insufficient to recommend it. Nor do the trials establish efficacy without monitoring. (LLM, conf=0.86)
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Computer-based training for cognitive behavioral therapy (CBT4CBT): A mixed methods investigation
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Self-citationA Systematic Review on the Effectiveness of Cognitive Behavioral Therapy in Substance Use Disorders
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- Authors
- Kiluk, B. D.
- Affiliations
- Yale University (US)
- Corresponding author
- Kiluk, Brian D.
- ORCID
- Kiluk, Brian D.
- Venue
- Perspectives on Behavior Science
- Published
- 2019-06-05
- Volume
- 42
- Issue
- 3
- Pages
- 465-478
- ISSN
- 2520-8969 (ISSN-L)
- 2520-8977
- PMC
- PMC6768920
- OpenAlex
- W2949037148
- Cited by
- 25
- References
- 86
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 4 · 2023: 5 · 2022: 5 · 2021: 1 · 2020: 1
- FWCI
- 1.33
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Perspectives on Behavior Science (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (R01AA024122)
- National Institute on Drug Abuse (P50DA09241)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- computerized cognitive behavioral therapy, substance use disorders, computer-based intervention, behavior change mechanisms, coping strategies, alcohol consumption, drug use, adjunctive therapy, dissemination and implementation, treatment durability
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