Cited by 1,189Health Promotion and Cardiovascular PreventionCardiovascular Health and Risk FactorsLipoproteins and Cardiovascular Health

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

A general cardiovascular risk profile: The Framingham study

Kannel, William B., McGee, Daniel, Gordon, Tavia·1976·The American Journal of Cardiology

Abstract

Persons at high risk of cardiovascular disease can be effectively identified from a measurement of their serum cholesterol and blood pressure, a smoking history, an electrocardiogram and a determination of glucose intolerance. One general function for identifying persons at high risk of cardiovascular disease is also effective in identifying persons at risk for each of the specific diseases, coronary heart disease, atherothrombotic brain infarction, hypertensive heart disease and intermittent claudication, even though the variables used have a different impact on each particular disease. The 10 percent of persons identified with use of this function as at highest risk accounted for about one fifth of the 8 year incidence of coronary heart disease and about one third of the 8 year incidence of atherothrombotic brain infarction, hypertensive heart disease and intermittent claudication. Hence the function provides an economic and efficient method of identifying persons at high cardiovascular risk who need preventive treatment and persons at low risk who need not be alarmed about one moderately elevated risk characteristic.

Overview

Integrity signals

Registry

Crossref · 10.1016/0002-9149(76)90061-8

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

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Verification

Claims the paper makes

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Claims other papers make about this one

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  • The 10-year risk estimates in the 1998 Framingham score classified people as low, intermediate, or high risk for future coronary heart disease.

    “The 10-year risk estimates used in the 1998 score provided a convenient way to classify individuals as low, intermediate, or high risk for future coronary heart disease.”
  • The 1998 Wilson Framingham Risk Score for coronary heart disease became the basis of the risk calculator adopted by the Adult Treatment Panel of the National Cholesterol Education Program in the United States.

    “The best known risk profile is the Framingham Risk Score for coronary heart disease, published in 1998 by Wilson and colleagues.50 This function became the basis of the risk calculator adopted by the Adult Treatment Panel of the National Cholesterol Education Program in the United States.51”
  • The 1998 Framingham risk model used risk factor categories instead of continuous values, allowing clinicians to use lookup tables for risk estimates.

    “Compared with previously published functions, the 1998 model substituted risk factor categories in the place of continuous values, which enabled clinicians to use lookup tables to obtain risk estimates.”
  • The 1998 Framingham Risk Score, adopted by the National Cholesterol Education Program, contained both total and HDL cholesterol.

    “Notably, the 1998 version of the Framingham Risk Score, adopted by the National Cholesterol Education Program, contained both total and HDL cholesterol.50”

Citations

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Research works printed but not linked: 1

  1. 1970, Circulation, 42, A-55

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Metadata

Authors
Kannel, W. B., McGee, D., & Gordon, T.
Affiliations
National Institutes of Health (US)
Corresponding author
Kannel, William B.
Venue
The American Journal of Cardiology
Publisher
Elsevier BV
Published
1976-07
Volume
38
Issue
1
Pages
46-51
ISSN
0002-9149 (ISSN-L)
OpenAlex
W2031564429
Cited by
1,189
References
3
Citations by year
2026: 18 · 2025: 30 · 2024: 29 · 2023: 37 · 2022: 31 · 2021: 27 · 2020: 37 · 2019: 30 · 2018: 31 · 2017: 42 · 2016: 36 · 2015: 38 · 2014: 52 · 2013: 48 · 2012: 29
FWCI
21.77
Type
journal article
Language
en
Open access
closed
Locations
  • The American Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Keywords
cardiovascular risk profile, coronary artery disease, atherothrombotic brain infarction, hypertensive heart disease, intermittent claudication, serum cholesterol, blood pressure, smoking history, electrocardiogram, impaired glucose tolerance, risk function, disease incidence, prophylaxis
MeSH terms
Adult, Age Factors, Aged, Cardiovascular Diseases, Female, Cardiomegaly, Humans, Hypercholesterolemia, Hypertension, Life Style, Male, Massachusetts, Middle Aged, Obesity, Probability, Regression Analysis, Risk, Sex Factors, Smoking, Diabetes Complications

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