Cited by 112Neuropeptides and Animal PhysiologyNeuroendocrine regulation and behaviorPain Mechanisms and Treatments

An immuno-electronmicroscopical study comparing vasopressin, oxytocin, substance P and enkephalin containing nerve terminals in the nucleus of the solitary tract of the rat

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Voorn, P., Buijs, R.M.·1983·Brain Research

Abstract

Vasopressin, oxytocin, substance P and enkephalin fibers were demonstrated to terminate synaptically in the nucleus of the solitary tract. The detergent Triton X-100 proved to be indispensable for the demonstration of vasopressin and oxytocin while enkephalin and substance P could be visualized very well without it. The differences with respect to morphology between these 4 peptides disappeared when Triton X-100 was used in both groups.

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Crossref · 10.1016/0006-8993(83)90809-0

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  • Electron microscopic analysis has revealed dense core vesicles containing AVP- and OT-ir in terminals located in synaptic regions of brain areas such as the habenula, lateral septum, amygdala, supraoptic nuclei, ventromedial hypothalamus, and the nucleus of the solitary tract.

    “For example, electron microscopic analysis has revealed dense core vesicles containing AVP- and OT-ir in terminals located in synaptic regions of brain areas such as the habenula, lateral septum, amygdala, supraoptic nuclei, ventromedial hypothalamus and the nucleus of the solitary tract [98; 99; 100; 101; 102; 103; 104].”

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Authors
Voorn, P., & Buijs, R. M.
Corresponding author
Buijs, R.M.
Venue
Brain Research
Publisher
Elsevier BV
Published
1983-06
Volume
270
Issue
1
Pages
169-173
ISSN
0006-8993 (ISSN-L)
OpenAlex
W1996774439
Cited by
112
References
19
Citations by year
2022: 1 · 2021: 3 · 2020: 3 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2014: 2
FWCI
2.77
Type
journal article
Language
en
Open access
Locations
  • Brain Research (publishedVersion)
  • PubMed (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
  • KNAW Research Portal (The Royal Netherlands Academy of Arts and Sciences) (submittedVersion)
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
  • Health Sciences › Medicine › Physiology › Pain Mechanisms and Treatments
Keywords
vasopressin, oxytocin, substance P, enkephalin, nucleus tractus solitarius, synaptic terminals, Triton X-100, rats
MeSH terms
Animals, Axons, Enkephalins, Immunoassay, Medulla Oblongata, Microscopy, Electron, Neurons, Oxytocin, Substance P, Vasopressins, Rats

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